Background and aims: Diabetes is a metabolic disorder associated with many complications; caregivers’ self-efficacy is essential for sustained home management. The study aimed to find out the effects of nursing intervention programs on caregivers’ self-efficacy regarding adhering to home-based management of child to type1 diabetes mellitus. Methods: A quasi‐experimental study design on home-based nursing intervention was conducted and recruited 60 caregivers who took homecare for their diabetes type 1. The systematic sampling method was used to select the participants Who were divided into two groups (30 in an intervention group and 30 in a control group) and who were registered at the Gulan General Hospital in Akre / Duhok city of Iraqi Kurdistan region. Verbal consent was obtained. starting from 3rd of January to the end of 5th September 2022.The home-based lesions were adopted for 5 months, Mann-Whitney U test, and T-Test ware used to identify the comparison between the variables. A p-value of ≤ 0.05, considered statistically significant. Results: There is no significant association between the control and study groups at the pretest before conducting the intervention program, while after conducting a home-based program for the intervention group, the results show that there was a highly significant difference between the pre and post test, the result reflects and successful program to change the self-efficacy of the caregivers from intervention, and it means a provided compared with the control group ( non-intervention group), at a p-value of ≤ 0.05. Conclusion: The results show that the caregivers who participated in the program (Intervention group), were successfully adapted to the self-efficacy program. Applying the program to a wider range of caregivers, to adhere to the caregivers and improve their self -efficacy toward home-based management of type 1 diabetes mellitus.