Introduction: Sierra Leone faces significant healthcare challenges, including a shortage of healthcare professionals and concerns over the competence and ethical behaviour of nurses. Understanding the role of nurse educators in shaping the next generation of nurses is essential for addressing these challenges and improving healthcare delivery. Aim: To examine the impact of Nurse Educators’ attitudes on Nursing Students' academic performance and Ethical Growth at the Department of Nursing, Eastern Technical University of Sierra Leone. Methods: The study was a descriptive cross-sectional mixed-methods design, incorporating both quantitative and qualitative approaches, and utilised a stratified random sampling method to survey students between August and October 2023. The sample size was determined using an online Raosoft sample size calculator and the WallStreetMojo formula, ensuring a 5% margin of error at a 95% confidence interval. Data collection involved a self-designed 5-point Likert scale questionnaire, assessed for reliability and internal consistency using Cronbach's alpha, with analysis conducted through descriptive statistics, factor analysis, and the chi-square test of independence, maintaining a significance level of p ≤ 0.05. Result: Findings that emerged include the positive influence of educators' attitudes, commitment, and effective teaching methods, underscoring their crucial role in cultivating a conducive learning environment. Similarly, negative findings reveal apprehensions regarding clinical preparation, student participation, and the perceived influence of educators' behaviour on academic progress and motivation. Statistical analyses, including chi-square tests, reveal the statistical significance of the relationships between nurse educators' attitudes and students’ academic performance and ethical growth. Qualitative themes, including respect, fairness, and equality emerged, highlighting the intricate nature of professional relationships between educators and students. Conclusion: The study sheds light on nurse educators' influence on students' academic performance and ethical growth, emphasising the importance of addressing both positive aspects and areas of concern for a holistic learning environment. The qualitative responses emphasised a collective desire for a supportive and respectful atmosphere and implementing the study's recommendations is seen as vital for enhancing professional relationships in nursing education.