ABSTRACT Botero’s Della Ragion di Stato has a monarchical character that has been overlooked or taken for granted. This is due to the successful reception of the reason of state formula, which justifies any kind of political regime, including principalities, republics, and monarchies, regardless of the author’s preferences. However, there is a clear distinction between monarchy and reason of state that requires further discussion. Botero not only uses Machiavellian language when referring to a political community (as res publica) or the prince (as a metaphor for centralized monarchies), but also reappropriates it. In addition, he goes beyond this to explain a non-legal path to absolute sovereignty, which differs from Jean Bodin’s (1530–96) idea of the king as being above the law and Thomas Hobbes’ (1588–1679) theory of authorization and the social contract. This paper argues that Botero’s concept of reason of state can be understood as a complex process of reduction to unity, similar to God’s creation and the functioning of the natural world. Despite its contradictions and limitations, it grants the prince an unusual supremacy and control over society.