History Of Intermittent Bleeding Research Articles

Pyogenic granuloma of the glans penis after angioembolisation procedure

A 8-year-old male child was referred to the Dermatologic clinic for a protruding growth on the glans penis that had appeared and started growing rapidly over a period of past 7 days since the child underwent the angioembolisation procedure for Penile Arteriovenous (AV) malformation. There was a history of intermittent bleeding from the well-established lesion. Clinical examination revealed a single, well-defined, rounded, sessile, fleshy red, vascular, polypoidal growth of size 3.5 x 3 cm present circumferentially around the urethral opening on the glans penis (Figure 1). The patient’s clinical course and a physical examination for glans penis lesion was suggestive of a Pyogenic Granuloma (PG). Histopathological examination of the mucosal biopsy from the lesion confirmed the diagnosis showing proliferating vessels surrounded by a mixed inflammatory infiltrate comprising lymphocytes, plasma cells, neutrophils, and eosinophils. After the confirmation of the diagnosis, the lesion was completely excised under local anaesthesia. During the postoperative follow-up, there was no recurrence six months after the surgery.

Gestational trophoblastic tumor after medical abortion

Background Nonmetastatic gestational trophoblastic tumor occurring after early elective medical abortion using mifepristone and misoprostol is unusual. Case A young woman at 6 to 7 weeks’ gestation presented with brown spotting requesting medical abortion. Pretreatment ultrasound was consistent with an abnormal pregnancy. Passage of tissue ensued after mifepristone–misoprostol administration. Recovery was normal, with a postabortion ultrasound on day 16 showing a reduction in intracavitary contents. The patient declined surveillance with serial β–human chorionic gonadotropin (β-hCG) levels and was lost to follow-up. Sixty days after initial treatment, she presented to a hospital with a history of intermittent bleeding and underwent curettage, revealing a complete hydatidiform mole. Chemotherapy was instituted when levels of hCG plateaued. Complete hCG regression occurred after three weekly injections of methotrexate, and postmolar surveillance is uneventful to date. Conclusion Gestational trophoblastic tumor may occur after early medical abortion.