The present study has been conducted with the purpose to investigate the effect of life skills based education on the adjustment of generation z adolescent learners. The present study is experimental type in which pre- test and post- test design were used. Total 640 students were selected, 340 in experimental group and 340 in control group as Sample for the current study. The tool used for this study was Adjustment Inventory of School Students (Prof.A.K.P.Sinha and Prof.R.P.Singh). 2x2x2x2 ANCOVA was used to analyze the data. Findings showed that Life Skill Based Education has higher positive impact on the adjustment of experimental group than control group. It showed that teacher should integrate life skills in the routine class while teaching.