High Stability Research Articles

Designing Artificial Laccase Catalysts by Introducing Substrate Oxidation Metals into Oxygen-Reducing Metal-Organic Frameworks: Cu-doped ZIF-67.

Laccase, a multi-copper oxidase, is limited by its optimal temperature range and isolation costs. To overcome these challenges, we synthesized copper-doped zeolitic imidazolate framework-67 (Cu-ZIF-67) with 16 mol% Cu as an artificial laccase catalyst. The introduced Cu site acts as the phenol oxidation site, and Co-based ZIF-67 is the four-electron oxygen reduction site. Laccase also employs this division of oxidation and reduction sites. Cu-doped ZIF-67 demonstrated significant catalytic activity, superior to natural laccase, especially at elevated temperatures, and maintained stability across multiple reaction cycles. These findings suggest that Cu-doped ZIF-67 is a robust, reusable alternative for industrial applications requiring high thermal stability and efficient catalysis.

Ternary π-π Stacking Complexes by Allosteric Regulation in Multilayer Nanographenes.

Construction of π-π stacking supramolecular complexes with more than two different components is challenging due to the weak and directionless nature of dispersion interactions. Here, we report ternary complexes of a ditopic nanographene tetraimide (1), α-substituted phthalocyanine (Pc), and polyaromatic hydrocarbons (PAHs) in solution and the crystalline state via allosteric regulation. Binding of one Pc gives rise to significant distortion and conformational changes in 1 that in turn lead to the inhibition of the second binding of Pc. The conformational changes associated with first binding allowed an allosteric binding of a third component (PAHs) to form ternary complexes in solution. 1H NMR titration revealed moderately high thermodynamic stability for the ternary complexes in CDCl3. Competition between allosterically regulated ternary complexes ([Pc·1·PAH]) and 1:2 stoichiometric binary complexes of 1 with PAHs ([PAH·1·PAH]) was elucidated. Further, the selective formation of ternary complexes in solution led to the generation of ternary cocrystals from a 1:1:1 mixture of three components in solution. Our work shows that large π-conjugated nanographenes designed with allosteric recognition sites allow the construction of multilayer ternary complexes in solution and the solid state even with dispersive π-π interactions.

Synthesis of novel indazole derivatives as inhibitors of diabetics II along with molecular docking and simulation study

In the light of the pharmacological significance of the indazole and 1, 3, 4-thiadiazole scaffold, hybrid analogs of indazole and 1, 3, 4-thiadiazole (1–14) were synthesized, identified using HREI-MS, 1H, and 13CNMR, and their capability for inhibition of α-amylase and α-glucosidase enzymes was evaluated. Generally, most of the synthesized derivatives of the series exhibited good inhibition activity in comparison to the reference drug acarbose with IC50 value of 10.30 ± 0.20 for α-amylase, and 9.80 ± 0.20 for α-glucosidase. Amongst the synthesized derivatives, fluoro substituted analog 10 appeared to be the most potent inhibitor having IC50 value of 9.90 ± 0.30 for α-amylase and 9.20 ± 0.30 for α-glucosidase. A structure activity relationship (SAR) for the series was established based on electronic effects and the positions of various groups on the phenyl ring. To comprehend the chemicals' binding interactions, molecular docking along with simulation study were also carried out. Compound 10 was ranked top in the series based on docking score and interactions with receptors. Compound 10 establish more H-bond contacts with the active site's residue of alpha-amylase and α-glucosidase as compared to all other compounds. Furthermore, 10 was found to be highly stable throughout 50 ns MD simulation. As compared to the control drug, 10 revealed high stability with both α-amylase and α-glucosidase enzymes during molecular dynamics simulation.

Zr-Doped High-Voltage Spinel LiNi0.5Mn1.5O4 Manufactured via the Coprecipitation Method.

Lithium nickel manganese oxide (LiNi0.5Mn1.5O4, LNMO) provides an elevated operating potential of 4.7 V and a theoretical capacity of 147 mAh g-1, without the need for expensive cobalt. Zr-doped LNMO was synthesized using the coprecipitation technique with Couette-Taylor flow. FE-SEM images and TEM SAED patterns revealed that Zr-doped LNMO formed truncated octahedral structures with exposed (100) crystal facets. When compared to undoped LNMO, Zr-doped LNMO exhibited superior electrochemical performance. Electrochemical evaluations showed that Zr0.1-LNMO achieved 85.9% rate capability at 10 C, significantly outperforming the 69.1% of bare LNMO. In addition, Zr0.1-LNMO exhibited high stability, maintaining 76.8% of the discharge capacity even after 100 cycles.

The Identification of Microstructural Changes in High-Temperature Superconducting Tapes for Superconducting Fault Current Limiters

HTS 2G tapes used in Superconducting Fault Current Limiters (SFCLs) have properties that allow for the effective limitation of short-circuit currents; however, due to the specificity of the device operation, they should be characterized by the high stability of the parameters when repeatedly leaving the superconducting state. During the operation of SFCLs, a situation may occur in which the parameters of the HTS tapes used will change several times as a result of the action of short-circuit currents that exceed the critical current IC of the superconductor of the tape used. This paper presents the results of microstructural tests of 2G HTS tapes intended for SFCLs, subjected to surge currents corresponding to prospective short-circuit currents with values higher than their critical currents IC and for which IC changes were observed. The HTS tapes were examined using a JEOL 7600F field emission scanning electron microscope (SEM), and their chemical composition was analyzed using Energy-Dispersive X-ray Spectroscopy (EDS). The test results indicate the possibility of micro-damage in the form of cracks in the superconductor layer, as well as the interruption of the buffer layers and the oxidation of the silver layers. The analysis of the chemical composition of the HTS tape layers may indicate the occurrence of diffusion processes.

Incorporation of enzyme-mimic species in porous materials for the construction of porous biomimetic catalysts.

The unique catalytic properties of natural enzymes have inspired chemists to develop biomimetic catalyst platforms for the intention of retaining the unique functions and solving the application limitations of enzymes, such as high costs, instability and unrecyclable ability. Porous materials possess unique advantages for the construction of biomimetic catalysts, such as high surface areas, thermal stability, permanent porosity and tunability. These characteristics make them ideal porous matrices for the construction of biomimetic catalysts by immobilizing enzyme-mimic active sites inside porous materials. The developed porous biomimetic catalysts demonstrate high activity, selectivity and stability. In this feature article, we categorize and discuss the recently developed strategies for introducing enzyme-mimic active species inside porous materials, which are based on the type of employed porous materials, including metal-organic frameworks (MOFs), covalent organic frameworks (COFs), molecular sieves, porous metal silicate (PMS) materials and porous carbon materials. The advantages and limitations of these porous materials-based biomimetic catalysts are discussed, and the challenges and future directions in this field are also highlighted.

Molecular recognition of peptides and proteins by cucurbit[n]urils: systems and applications.

The development of methodology for attaching ligand binding sites to proteins of interest has accelerated biomedical science. Such protein tags have widespread applications as well as properties that significantly limit their utility. This review describes the mechanisms and applications of supramolecular systems comprising the synthetic receptors cucurbit[7]uril (Q7) or cucurbit[8]uril (Q8) and their polypeptide ligands. Molecular recognition of peptides and proteins occurs at sites of 1-3 amino acids with high selectivity and affinity via several distinct mechanisms, which are supported by extensive thermodynamic and structural studies in aqueous media. The commercial availability, low cost, high stability, and biocompatibility of these synthetic receptors has led to the development of myriad applications. This comprehensive review compiles the molecular recognition studies and the resulting applications with the goals of providing a valuable resource to the community and inspiring the next generation of innovation.

Therapeutic effect of Micro-Implant Anchorage in orthodontics

Objective: Micro implant anchorage (MIA), as a new orthodontic treatment technique, has the characteristics of simple operation, light trauma, and high stability, and has been widely used in clinical practice. This study compared the therapeutic effects of MIA and the traditional straight wire appliance (SWA) in orthodontic practice. Methods: Clinical data of 119 patients who underwent orthodontic treatment in Yulin First Hospital from January 2022 to January 2023 were retrospectively analyzed. According to the treatment records, 61 patients received MIA orthodontic treatment (MIA group), and 58 patients received traditional straight wire appliance (SWA) orthodontic treatment (SWA group). Treatment effect, periodontal index, and levels of osteoprotegerin (OPG), interleukin-6 (IL6) and high-sensitivity C-reactive protein (hsCRP) of the two groups were compared. Results: The total efficacy of MIA group was significantly higher than that of SWA group (P<0.05). After the treatment, bleeding index (BI), plaque index (PLI), probing depth (PD) and looseness in the MIA group were significantly lower than those in the SWA group (P<0.05). After the treatment, levels of OPG were significantly higher, while IL6 and hsCRP levels were significantly lower in the MIA compared to the SWA group (P<0.05). MIA was associated with significantly lower complication rate compared to the SWA (P<0.05). Conclusions: Compared with SWA, MIA is associated with better orthodontic effect. This mode of treatment can increase OPG levels, reduce inflammation, and lower the risk of complications. doi: https://doi.org/10.12669/pjms.40.10.10442 How to cite this: Shi Y, Mi L, Liu J, Liu X, Hao Y. Therapeutic effect of Micro-Implant Anchorage in orthodontics. Pak J Med Sci. 2024;40(10):2293-2298. doi: https://doi.org/10.12669/pjms.40.10.10442 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Identification and Analysis of Potential Biomarkers Associated with Neutrophil Extracellular Traps in Cervicitis.

Early diagnosis of cervicitis is important. Previous studies have found that neutrophil extracellular traps (NETs) play pro-inflammatory and anti-inflammatory roles in many diseases, suggesting that they may be involved in the inflammation of the uterine cervix and NETs-related genes may serve as biomarkers of cervicitis. However, what NETs-related genes are associated with cervicitis remains to be determined. Transcriptome analysis was performed using samples of exfoliated cervical cells from 15 patients with cervicitis and 15 patients without cervicitis as the control group. First, the intersection of differentially expressed genes (DEGs) and neutrophil extracellular trap-related genes (NETRGs) were taken to obtain genes, followed by functional enrichment analysis. We obtained hub genes through two machine learning algorithms. We then performed Artificial Neural Network (ANN) and nomogram construction, confusion matrix, receiver operating characteristic (ROC), gene set enrichment analysis (GSEA), and immune cell infiltration analysis. Moreover, we constructed ceRNA network, mRNA-transcription factor (TF) network, and hub genes-drug network. We obtained 19 intersecting genes by intersecting 1398 DEGs and 136 NETRGs. 5 hub genes were obtained through 2 machine learning algorithms, namely PKM, ATG7, CTSG, RIPK3, and ENO1. Confusion matrix and ROC curve evaluation ANN model showed high accuracy and stability. A nomogram containing the 5 hub genes was established to assess the disease rate in patients. The correlation analysis revealed that the expression of ATG7 was synergistic with RIPK3. The GSEA showed that most of the hub genes were related to ECM receptor interactions. It was predicted that the ceRNA network contained 2 hub genes, 3 targeted miRNAs, and 27 targeted lnRNAs, and that 5 mRNAs were regulated by 28 TFs. In addition, 36 small molecule drugs that target hub genes may improve the treatment of cervicitis. In this study, five hub genes (PKM, ATG7, CTSG, RIPK3, ENO1) provided new directions for the diagnosis and treatment of patients with cervicitis.

Heterointerface of Monodispersed Ultrathin-MnO2@Amorphous Carbon to Attain Durable Lattice Oxygen Redox Chemistry through Creation of Dual Lattice Oxygens.

Lattice oxygen (OL) redox chemistry is a key to alleviating the energy and environmental crisis, but it faces challenges in activating the OL while ensuring structural stability. We disclosed herein that engineering a heterogeneous interface between ultrathin oxide and amorphous carbon can attain the durable OL redox chemistry without introducing catalytically impure sites. To this end, we proposed a green strategy to grow ∼3.9 nm-thickness wrinkled δ-MnO2 nanosheets that are rich in defects and are vertically aligned on amorphous carbon spheres. Experiments and calculations reveal that the electrons can easily migrate from the amorphous carbon to MnO2 at the δ-MnO2@C heterointerface. The heterogeneous interfaces can not only regulate the Mn-O bond and create oxygen defects in δ-MnO2 but also introduce lattice oxygen with varying reactivities. Specifically, the δ-MnO2@C structure carries more activated lattice oxygen that contributes to the enhanced activity on catalytic oxidation of bioderived 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA), with a high FDCA formation rate of 1759 μmol gcat-1 h-1 and a high selectivity of 95%. The heterogeneous interface of MnO2@C also brings inert lattice oxygen, so that it manifests high structural stability during the oxidation reactions. This work deepens the fundamental understandings in the engineering of lattice oxygen for durable lattice oxygen redox chemistry and showcases an effective interface technique in creating advanced catalysts for clean sustainable energy.

Ionized Phenanthroline Derivatives Suppressing Interface Chemical Interactions with Active Layer for High-efficiency Organic Solar Cells with Exceptional Device Stability.

The contact interface between the charge transport interlayer and the active layer is crucial for the non-fullerene organic solar cells (NF OSCs) to achieve high efficiency and long-term stability. In this study, two novel phenanthroline (Phen) derivatives, tbp-Phen and tbp-PhenBr, are developed as efficient cathode interfacial materials (CIMs). The larger steric hindrance substituents and the ionization of nitrogen atoms on the Phen framework jointly enable the tbp-PhenBr CIM with a stable film morphology and immensely suppress the detrimental interface chemical interactions with the NF active layer. Consequently, tbp-PhenBr-based OSC achieves a higher efficiency (PCE=16.34%) than bathocuproine (BCP)-based control device (PCE=13.70%) using PM6:Y6 as the active layer. More importantly, the tbp-PhenBr-based device maintains 80% of its initial efficiency (T80) for 3264 h in dark conditions and 220 h after being heated at 85°C, significantly outperforming the BCP-based device. The tbp-PhenBr CIM also shows broad applicability across various binary and ternary active layer systems, affording a notable PCE of 19.49%. Additionally, the tbp-PhenBr CIM can be processed via a thermal evaporation technique and the prepared devices exhibit high reproducibility. This work provides innovative insights into the molecular design of the CIMs for stable and efficient NF OSCs.

PEDOT:PSS Nanoparticle Membranes for Organic Solvent Nanofiltration.

Recycling of valuable solutes and recovery of organic solvents via organic solvent nanofiltration (OSN) are important for sustainable development. However, the trade-off between solvent permeability and solute rejection hampers the application of OSN membranes. To address this issue, the poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) nanoparticle membrane with hierarchical pores is constructed for OSN via vacuum filtration. The small pores (the free volume of the polymer chain) charge for the solute rejection (high rejection efficiency for low molecule weight solute) and allow solvent passing while the large pores (the void between two PEDOT:PSS nanoparticles) promote the solvent transport. Owing to the lack of connectivity among the large pores, the fabricated PEDOT:PSS nanoparticle membrane enhanced solvent permeance while maintaining a high solute rejection efficiency. The optimized PEDOT:PSS membrane affords a MeOH permeance of 7.2 L m-2 h-1 bar-1 with over 90% rejection of organic dyes, food additives, and photocatalysts. Moreover, the rigidity of PEDOT endows the membrane with distinctive stability under high-pressure conditions. The membrane is used to recycle the valuable catalysts in a methanol solution for 150h, maintaining good separation performance. Considering its high separation performance and stability, the proposed PEDOT:PSS membrane has great potential for industrial applications.

Infiltration of glass nanofiber-reinforced polylactic acid into delignified hardwood toward photoluminescent and mechanically reliable smart windows

Ultraviolet-protective, mechanically reliable, and photoresponsive wood that can switch color under ultraviolet light was developed. A combination of alkaline earth-doped strontium aluminate (ASA) as a photoluminescent pigment and glass nanofiber-supported polylactic acid as a hosting agent was infused into a delignified wood, producing transparent wood with photochromic activity. The ASA phosphor has proven high thermal stability and photostability. A typical process for producing colorless photoluminescent wood includes the well-dispersion of ASA in glass nanofiber-supported polylactic acid without agglomeration. As proven by the coloration measurements, the current photoluminescent wood becomes green under ultraviolet light and remains transparent under daylight. Transmission electron microscopy (TEM) and scanning electron microscope (SEM) were employed to determine the morphology of the phosphor particles and glass fibers, demonstrating sizes of 12–21 nm and 50–125 nm, respectively. The luminescent wooden samples were studied by numerous microscopic and spectroscopic techniques, including SEM, X-ray fluorescence (XRF), and energy-dispersive X-ray (EDX). Upon excitation at 365 nm, the luminescence wood demonstrated an emission peak at 518 nm. When increasing the ASA concentration, the photoluminescent hardwoods displayed improved ultraviolet protection and better water resistance. The responsiveness of the luminescent wood to UV irradiation was fast and reversible.

Improved Faster R-CNN Based on Multi-Scale Module for Detecting Weak Ground Targets in Remote Sensing Images

In order to optimize the detection capability of small and weak ground targets in remote sensing images, a remote sensing image ground weak target detection method based on multi-scale module improved Faster R-CNN is proposed. By adjusting the Region Proposal Network (RPN) and Region of Interest (RoI) pooling layers, the model is better suited for feature extraction and classification of small targets. Generate feature maps at multiple scales by introducing additional convolutional layers to process inputs at different resolutions, with each layer focusing on targets within a specific size range. These multi-scale features are integrated and input into RPN to provide richer target proposal characteristics. By using image transformation techniques such as scaling, cropping, and rotation, the training dataset is expanded to simulate different small target scenes, enhancing the model’s adaptability to changes in target size, direction, and environment. The experimental results show that the proposed method not only outperforms other models in accuracy, recall, and F1 score, but also maintains high consistency and stability across different datasets. Its significant advantage in mean accuracy (MAP) further proves its reliability and effectiveness in remote sensing applications.

A preliminary investigation of banana pseudo-stem (Musa cavendish) for pulp and paper production: morphology, chemical composition, FTIR, XRD and thermogravimetric analysis

Abstract In today’s world, the use of paper and cardboard increasing but the availability of raw materials and the environmental impact on the paper industry is a big concern. To address these concerns, researchers are exploring the potential of agricultural waste products as raw materials for pulp production. This study uses morphological, chemical composition, FTIR, XRD, and thermogravimetric analysis to examine the potential of banana pseudo-stem as a raw material for paper pulp to address environmental concerns and raw material shortages in the paper industry. The study reveals favorable characteristics for papermaking, including long fiber length (1750 μm), thin cell wall thickness (9.7 μm), and large lumen diameter (22.15 μm). The chemical composition of banana pseudo-stem contains cellulose (44.93 %), hemicellulose (23.7 %), and Klason lignin (11.1) showing its suitability for pulp production. FTIR analysis highlights the functional groups present on the banana pseudo-stem. The XRD analysis shows that it has a similar cellulosic peak and crystallinity index with common raw materials used in pulp production. The thermogravimetric analysis shows that the banana pseudo-stem has high thermal stability. The findings demonstrate that banana pseudo-stem, both by itself and in combination with other raw materials, might be a potential raw material for the pulp production.

High-Performance Flexible PLA/BTO-Based Pressure Sensor for Motion Monitoring and Human-Computer Interaction.

Flexible electronics show wide application prospects in electronic skin, health monitoring, and human-machine interfacing. As an essential part of flexible electronics, flexible pressure sensors have become a compelling subject of academic research. There is an urgent need to develop piezoelectric sensors with high sensitivity and stability. In this work, the high flexibility of polylactic acid (PLA) film and the excellent ferroelectric properties and high dielectric constant of tetragonal barium titanate (BTO) led to their use as filling materials to fabricate flexible piezoelectric composite films by spinning coating. PLA is used to produce flexible binding substrates, and BTO is added to the composite to enhance its electrical output by improving its piezoelectric performance. The peak output voltage of the PLA/BTO tetragonal piezoelectric film is 22.57 V, and the maximum short-circuit current was 3041 nA. Durability tests showed that during 40,000 s of continuous operation, in the range of 15~120 kPa, the linear relationship between pressure and the film was excellent, the sensitivity for the output voltage is 0.176 V/kPa, and the output current is 27.77 nA/kPa. The piezoelectric pressure sensor (PPS) also enables accurate motion detection, and the extensive capabilities of the PENG highlight its potential in advancing motion sensing and human-computer interactions.

Construction of all-solid-state ion-selective sensors using electrolyte-containing polymers.

All-solid-state NO3-, K+, NH4+, Na+, and Ca2+ ion-selective sensors (ISEs) were prepared using polyvinyl butyral (S-LEC®K KX-5). In the present case, polyvinyl butyral was used as a porous material to keep the internal solution of the respective ISE. All sensors exhibited near-Nernst responses in the concentration region between approximately 10-5 and 0.1moldm-3. To avoid the influence of KCl as interfering ions, MgSO4 was used as an electrolyte within the salt bridge. Although the liquid junction potential was generated, the potential difference was stabilized within about few minutes. The NO3--ISE showed high stability with no potential drift during 12h of continuous measurements and maintained high sensitivity even after 3weeks of storage in ultrapure water. Solidification of the internal solution is expected to make the sensor smaller and increase its mechanical strength. As an actual measurement, the sodium concentration in plasma samples using the Na+-ISE was measured to confirm agreement with literature values.

Garnet-Type Zinc Hexacyanoferrates as Lithium, Sodium, and Potassium Solid Electrolytes

Sodium-ion batteries offer an attractive alternative to lithium-based chemistries due to the lower cost and abundance of sodium compared to lithium. Using solid electrolytes instead of liquid ones in such batteries may help improve safety and energy density, but they need to combine easy processing with high stability toward the electrodes. Herein, we describe a new class of solid electrolytes that are accessible by room-temperature, aqueous synthesis. The materials exhibit a garnet-type zinc hexacyanoferrate framework with large diffusion channels for alkaline ions. Specifically, they show superionic behavior and allow for facile processing into pellets. We compare the structure, stability, and transport properties of lithium-, sodium-, and potassium-containing zinc hexacyanoferrates and find that Na2Zn3[Fe(CN)6]2 achieves the highest ionic conductivity of up to 0.21 mS/cm at room temperature. In addition, the electrochemical performance and stability of the latter solid electrolyte are examined in solid-state sodium-ion batteries.

Covalent Lysozyme Immobilization on Enzymatic Cellulose Nanocrystals.

Nanostructured materials represent promising substrates for biocatalyst immobilization and activation. Cellulose nanocrystals (CNCs), accessible from waste and/or renewable sources, are sustainable and biodegradable, show high specific surface area for anchoring a high number of enzymatic units, and high thermal and mechanical stability. In this work, we present a holistic enzyme-based approach to functional antibacterial materials by bioconjugation between the lysozyme from chicken egg white and enzymatic cellulose nanocrystals. The neutral CNCs were prepared by endoglucanase hydrolysis from Avicel. We explore the covalent immobilization of lysozyme on enzymatic CNCs and on their TEMPO oxidized derivatives (TO-CNCs), comparing immobilization yields, material properties, and enzymatic activities. The materials were characterized by X-ray diffractometry (XRD), attenuated total reflectance Fourier Transform infrared spectroscopy (ATR-FTIR), bicinchoninic acid (BCA) assay, field-emission scanning electron microscopy (FE-SEM) and dynamic light scattering (DLS). We demonstrate the higher overall efficiency of the immobilization process carried out on TO-CNCs, based on the success of covalent bonding and on the stability of the isolated bioconjugates.

Toward a green economy: Lignin-based hybrid materials as functional additives in flame-retardant polymer coatings

This study describes the combination of unique properties of lignin with TiO2 as an innovative and effective preparation method for high-performance flame-retardant additives that may be utilized as polymer coatings. The use of lignin resulted in numerous advantages including an increased number of functional groups, satisfactory biocompatibility, low toxicity, and high carbon content. The major benefit of lignin is associated with the reduced carbon footprint of the manufactured product. Lignin can be classified as a natural flame-retardant agent owing to the high amount of char formed during combustion. In turn, TiO2 exhibits high chemical stability and low operating costs and is considered a non-toxic and environmentally friendly material. During the experiments, commercial TiO2 in anatase crystallographic form, TiO2 synthesized from titanyl sulfate hydrate, and kraft lignin as well as organic–inorganic hybrid materials composed of these materials were evaluated as functional additives in epoxy-resin-based polymer coatings (Epidian 601) and their properties were investigated in detail. The cone colorimetry test confirmed that the obtained hybrids are effective flame-retardant additives for polymer coatings, with a notable fire hazard reduction observed for samples containing a synergistic system of titanium oxide and lignin. The coating with lignin was the most effective in fire suppression processes. The conducted thermal and mechanical investigations confirmed good performance properties of the coatings indicating thermal resistance up to 360 °C and Shore D hardness in a range of 80.36–86.28°Sh, accordingly. Optical profilometry investigations show that the lignin/TiO2 hybrids exhibit a stable topological surface shape as well as good dispersion and uniformity in the polymer matrix. All the conducted tests allowed confirmation that the presence of functional additives in polymer coatings in the form of lignin and TiO2 can be a promising alternative to non-biodegradable synthetic materials which improve flame-retardant properties.