High Pressure Levels Research Articles

Feasibility of a custom-tailored, evidence-based, theory-informed, intervention to prevent burnout and reduce stress for healthcare professionals: protocol for a single-arm trial

BackgroundHealthcare professionals face high levels of occupational stress, time pressure, workload, and poor organizational support. This makes them particularly vulnerable to burnout. The COVID-19 pandemic has further exacerbated this situation. This single-arm, multicenter, mixed-methods feasibility study pilots the LAGOM program: A tailored, evidence-based intervention to prevent burnout and reduce stress among healthcare professionals.MethodsParticipants will include healthcare professionals (N = 30) working at Charité–Universitätsmedizin Berlin and Immanuel Hospital, Berlin. LAGOM focuses on support for individual behavior change and personal resources and also addresses the organizational level. The intervention´s feasibility will be evaluated through a non-randomized feasibility trial with a mixed methods process evaluation. The exploratory primary study aims are to assess the acceptability and feasibility of the (1) evaluation procedures and of the (2) intervention content and structure using study records, standardized questionnaires, protocol checklists, and diaries. Exploratory effectiveness analysis will take place as well. Further, semi-structured interviews (n = 3 to 6) and electrophysiological measurements (n = 20) will be conducted.DiscussionCustom-tailored, well-implemented multi-level interventions are needed to prevent burnout and reduce stress among healthcare professionals. Long-term strategies are warranted to sustainably implement effective programs. This feasibility study helps to refine trial procedures and content of the LAGOM program for a randomized controlled trial to evaluate the intervention’s effectiveness.Trial registrationGerman Clinical Trials Register: DRKS00032014, registered 17th October 2023.

The effect of sleep effectiveness on examination scores of first year osteopathic medical students

Medical students frequently encounter high levels of stress and pressure, which can negatively affect their mental health and sleep quality, a key determinant of cognitive function and academic success. This study assesses the relationship between sleep effectiveness and academic performance among medical students. An observational, cross-sectional survey took place at A.T. Still University - School of Osteopathic Medicine in Arizona (ATSU-SOMA), involving participants from the 2027 cohort. The Pittsburgh Sleep Quality Index (PSQI) questionnaire was used and exam scores from the second exam of the fourth block were analyzed. For the purpose of our inquiry, the “Sleep Effectiveness” component score of the PSQI was used for our analysis. The results indicated a significant inverse relationship between sleep effectiveness and exam performance (R² = 0.087, p =0.000262), demonstrating that increased sleep effectiveness was associated with lower exam performance. The study highlights the sheer amounts of confounding variables in the preconceived notion that “,Sleep is the key for academic success.” This research suggests that academic performance is best explained by multiple variables rather than simply one. Future studies should investigate the long-term effects of sleep deprivation and explore interventions beyond sleep hygiene, including stress and time management strategies. Understanding the broader impact of sleep on medical education is essential for fostering better outcomes for students in both academic and clinical settings.

Suicide in young and middle-aged individuals: lessons from a psychosocial autopsy study

Abstract Background Sociodemographic characteristics of suicides are available from Statistics Netherlands. To improve suicide prevention, it is not only necessary to know who dies but also why people die. A psychosocial autopsy was conducted in the Netherlands to investigate differences in psychosocial characteristics and precipitating factors of suicides of young (<30) and middle-aged (40-70) suicide decedents. Methods Data were collected from bereaved individuals. A questionnaire detailed sociodemographic and psychosocial characteristics of the decedents. We reconstructed the suicidal process in the months preceding the suicide in an interview. Findings from the questionnaire and interview were integrated. An independent expert committee formulated recommendations for suicide prevention. Results 162 suicides were investigated. Young decedents showed high levels of substance use and academic pressure. Young adults with developmental disorders were vulnerable in the transition to adulthood. Young males reached out less to support and care. By contrast, suicides of young females were distinguished by comorbidity of psychiatric disorders, frequent suicidal behaviours, high levels of care use, wait lists and a loss of (treatment) perspective, harmful social media use and bullying. Work and financial problems were common in middle-aged decedents. Physical disability and pain were frequently mentioned for middle-aged females. Suicide in middle-aged males was characterized by financial distress, interpersonal conflicts such as divorce, high levels of binge drinking and addiction. Conclusions Our data provide a topology of the needs of individuals at risk for suicide. Suicide prevention strategies can be improved by better transition support and explicit suicide monitoring in young adults with a developmental disorder, active waitlist policies in mental healthcare, and improved collaboration between debt counsellors and mental care professionals based on shared accountability. Key messages • Bereaved individuals elucidated a wide range of psychosocial problems in suicide decedents. • Suicide prevention should adhere to a needs-based approach.

Effects of Window Green View Index on Stress Recovery of College Students from Psychological and Physiological Aspects

Students often experience high levels of daily academic pressure, spending extended periods within indoor classroom environments. Windows, as a medium of proximity to nature, play an important role in relieving stress. However, the broader implications of the Window Green View Index (WGVI) on individual well-being remain underexplored. This study aims to assess the effects of WGVI on stress recovery in college students by utilizing virtual reality technology to create five classroom environments with varying WGVI levels: 0%, 25%, 50%, 75%, and 100%. Twenty-four participants were subjected to the Trier Social Stress Test before engaging with the different WGVI scenarios for stress recovery. Both subjective assessments and objective physiological indicators were evaluated. Results indicated that participants exhibited the lowest Profile of Mood States (POMS) score (−4.50) and significantly improved systolic blood pressure recovery at a 25% WGVI level. The examination of EEG data revealed that the O2 channel in the occipital region exhibited the highest level of activity in the alpha frequency range during the experiment. Additionally, a significant association was observed between the EEG measurements and the subjective rating of stress. This study underscores the significance of incorporating WGVI into the design and planning of college buildings to promote mental health and well-being among students.

Metabolic adaptations of Shewanella eurypsychrophilus YLB-09 for survival in the high-pressure environment of the deep sea.

Elucidation of the adaptation mechanisms and survival strategies of deep-sea microorganisms to extreme environments could provide a theoretical basis for the industrial development of extreme enzymes. There is currently a lack of understanding of the metabolic adaptation mechanisms of deep-sea microorganisms to high-pressure environments. The objective of this study was to investigate the metabolic regulatory mechanisms enabling a strain of the deep-sea bacterium Shewanella eurypsychrophilus to thrive under high-pressure conditions. To achieve this, we used nuclear magnetic resonance-based metabolomic and RNA sequencing-based transcriptomic analyses of S. eurypsychrophilus strain YLB-09, which was previously isolated by our research group and shown to be capable of tolerating high pressure levels and low temperatures. We found that high-pressure conditions had pronounced impacts on the metabolic pattern of YLB-09, as evidenced by alterations in energy, amino acid, and glycerolipid metabolism, among other processes. YLB-09 adapted to the high-pressure conditions of the deep sea by switching from aerobic intracellular energy metabolism to trimethylamine N-oxide respiration, altering the amino acid profile, and regulating the composition and the fluidity of cell membrane. The findings of our study demonstrate the capacity of microorganisms to alter their metabolism in response to elevated pressure, thereby establishing a foundation for a more profound understanding of the survival mechanisms of life in high-pressure environments.

High hydrostatic pressure processing of whole buckwheat grains to obtain functional gluten-free ingredients: Effect of pressure and holding time

High Hydrostatic pressure (HHP) represents an environmental-friendly and efficient non-thermal technology capable of inducing changes that can lead to functional improvements on starchy materials preserving the nutritional value of the original flours. The development of gluten-free (GF) flours and ingredients remain a challenge due to the need to improve the nutritional and techno-functional aspects of these commodities. Pre-soaked whole buckwheat (BW) grains were subjected to HHP treatment under different processing conditions: two pressure levels (300–600 MPa) and three holding times (0-5-15 min) to evaluate the techno-functional and nutritional response of the resulting flours. Significant (p < 0.05) increases in water absorption capacity and swelling capacity were observed in the flours resulting from longer treatment times (5–15 min) and the highest-pressure level (600 MPa). Higher thermal stability was also observed in the pasting profiles obtained for these flours. Flours resulting from HHP treatments at 600 MPa for 15 min also showed higher antioxidant capacity (DPPH and ORAC). The resulting flour from these processing conditions was used at different concentrations (15, 30, 50, and 70 %) in a GF bread formulation. An increase in the elastic modulus values of the doughs, the specific volume of the resulting bread and a reduction in the crumb firmness were observed in the formulations containing the BW-modified flour compared to the counterparts made with a native flour. Therefore, it can be concluded that the HHP treatment of whole buckwheat grains represents an interesting alternative for the development of ingredients with suitable technological and nutritional properties for gluten-free bakery formulations.

Nonlinear biomechanical behaviour of extracranial carotid artery aneurysms in the framework of Windkessel effect via FSI technique

Extracranial carotid artery aneurysms (ECCA) lead to rupture and neurologic symptoms from embolisation, with potentially fatal outcomes. Investigating the biomechanical behaviour of EECA with blood flow dynamics is crucial for identifying regions more susceptible to rupture. A coupled three-dimensional (3D) Windkessel-framework and hyperelastic fluid-structure interaction (FSI) analysis of ECCAs with patient-specific geometries, was developed in this paper with a particular focus on hemodynamic parameters and the arterial wall's biomechanical response. The blood flow has been modelled as non-Newtonian, pulsatile, and turbulent. The biomechanical characteristics of the aneurysm and artery are characterised employing a 5-parameter Mooney-Rivlin hyperelasticity model. The Windkessel effect is also considered to efficiently simulate pressure profile of the outlets and to capture the dynamic changes over the cardiac cycle. The study found the aneurysm carotid artery exhibited the high levels of pressure, wall shear stress (WSS), oscillatory shear index (OSI), and relative residence time (RRT) compared to the healthy one. The deformation of the arterial wall and the corresponding von Mises (VM) stress were found significantly increased in aneurysm cases, in comparison to that of no aneurysm cases, which strongly correlated with the hemodynamic characteristics of the blood flow and the geometric features of the aneurysms. This escalation would intensify the risk of aneurysm wall rupture. These findings have critical implications for enhancing treatment strategies for patients with extracranial aneurysms.

Investigation of Sonication Parameters for Large-Volume Focused Ultrasound-Mediated Blood-Brain Barrier Permeability Enhancement Using a Clinical-Prototype Hemispherical Phased Array.

Background/Objectives: Focused ultrasound (FUS) and microbubble (MB) exposure is a promising technique for targeted drug delivery to the brain; however, refinement of protocols suitable for large-volume treatments in a clinical setting remains underexplored. Methods: Here, the impacts of various sonication parameters on blood-brain barrier (BBB) permeability enhancement and tissue damage were explored in rabbits using a clinical-prototype hemispherical phased array developed in-house, with real-time 3D MB cavitation imaging for exposure calibration. Initial experiments revealed that continuous manual agitation of MBs during infusion resulted in greater gadolinium (Gd) extravasation compared to gravity drip infusion. Subsequent experiments used low-dose MB infusion with continuous agitation and a low burst repetition frequency (0.2 Hz) to mimic conditions amenable to long-duration clinical treatments. Results: Key sonication parameters-target level (proportional to peak negative pressure), number of bursts, and burst length-significantly affected BBB permeability enhancement, with all parameters displaying a positive relationship with relative Gd contrast enhancement (p < 0.01). Even at high levels of BBB permeability enhancement, tissue damage was minimal, with low occurrences of hypointensities on T2*-weighted MRI. When accounting for relative Gd contrast enhancement, burst length had a significant impact on red blood cell extravasation detected in histological sections, with 1 ms bursts producing significantly greater levels compared to 10 ms bursts (p = 0.03), potentially due to the higher pressure levels required to generate equal levels of BBB permeability enhancement. Additionally, albumin and IgG extravasation correlated strongly with relative Gd contrast enhancement across sonication parameters, suggesting that protein extravasation can be predicted from non-invasive imaging. Conclusions: These findings contribute to the development of safer and more effective clinical protocols for FUS + MB exposure, potentially improving the efficacy of the approach.

Beyond delinquency and drug use: Links of peer pressure to long-term adolescent psychosocial development.

This study examined the predictors and sequelae of exposure to peer pressure from close friends in adolescence. Adolescents (99 female; 85 male) were followed from age 13 to 24 utilizing peer, parent, and romantic partner reports and observational data. Participants who were exposed to high levels of peer pressure as teens were more likely to experience higher levels of coercive behavior from romantic partners (as reported by those partners), as well as lower levels of parent-reported functional independence. All findings held even after accounting for baseline levels of teen assertiveness. Adolescents at risk for increasing exposure to peer pressure were characterized by poor-quality parent and peer relationships, as well as baseline deficits in ability to assert autonomy. Results suggest that exposure to peer pressure, aside from its potential effects on deviant or risky behavior, may reflect a powerful threat to the autonomy development process as adolescents transition from parents to peers as primary sources of support and interaction.

Elucidating the separation role of C3N slit-pore on N2/CH4 in coalbed methane

A hybrid approach integrating molecular dynamics (MD) and Grand Canonical Monte Carlo (GCMC) simulations was employed to investigate the separation efficacy of N2/CH4 across various C3N slit apertures. MD simulations enabled the determination of separation selectivity and diffusion coefficients of N2/CH4, thereby aiding in the elucidation of the separation mechanism. On the other hand, GCMC simulations provided insights into the adsorption isotherms and isosteric heats of N2 and CH4 within the C3N slit. These findings reveal that the highest selectivity of N2 over CH4 occurs at the zigzag-edge C3N with a pore size of 6.2 Å. However, this selectivity is accompanied by the smallest diffusion coefficient, attributable to size sieving effects. As the pore diameter increases, more gas molecules can permeate into the pores, leading to a rise in both the maximum adsorption capacity and the isosteric heat of methane adsorption. With increasing pressure, gas molecules tend to reach saturation at higher pressure levels. Our study primarily centers on examining the separation of N2/CH4 across various C3N slit-pores, encompassing both adsorption and diffusion phenomena. These findings offer theoretical insights and comprehension for the experimental separation of coalbed methane utilizing cheaper carbon-based materials.

Factors of Positive Leadership Affecting Optimistic Attitude toward Self-Efficacy in Clinic Staff in Universities

Nursing department workers are the largest group in a school clinic. They are also the most important of the human resources. The emotional burden of witnessing the stages of life is accompanied by the heavy work that creates an extremely high level of pressure. This is also an obstacle to a good doctor-patient relationship. Therefore, it emerges as an important research topic that can help to improve the situation as well as promote psychological health and self-efficacy of the school clinic staff. In order to fill in this research gap, school clinic staff of universities in Guangxi Zhuang autonomous region were selected as the research participants. A total of 450 copies of the questionnaire were distributed to the potential respondents. After removing the invalid and incomplete ones, 364 valid copies were retrieved, with a retrieval rate of 81%. The collected data were tested using Amos to understand the relationships among positive leadership, optimistic attitude, and self-efficacy. As a result of the analyses, it was found out that when they have a positive attitude, leaders of the clinic staff in universities can improve the attachment and self-confidence of the school clinic staff. This encourages them to have a higher level of willingness to contribute to the development of the institution. Another finding of the study was that a university leader should adopt a hands-on, positive paradigm to enable continuous development and create a positive working environment. Finally, it was found out that if a university leader builds a positive energy network, he can improve the coherence among the staff and encourage them to be willing to contribute by modelling other workers. According to the results, it is expected that this study will help clinic staff to generate optimistic attitude which promotes self-efficacy.

End Connectors Stress Analysis for Horizontal Pressure Vessel

The gas and oil industry extensively utilizes horizontal pressure vessels to store its primary sources. These vessels are designed to withstand high levels of pressure and to release contents in a controlled manner. Although the sphere-shaped storage container is widely regarded as a better-engineered structure, the ease of manufacturing makes horizontal pressure vessels the preferred choice. This paper presents an in-depth analysis of stress distribution in horizontal pressure vessels with various end connections, including hemispherical, ellipsoidal, flat head, and tori-spherical configurations. The study involves analytical and finite element analysis (FEA) to compare the stress distribution across these above-mentioned end connections. Key vessel dimensions, such as internal diameter, vessel thickness, and end connections, have been determined through analytical design. A detailed structural analysis aided in determining which among the different end connectors is best suitable for industry usage.

Selection of the method for determination of ignition delay of hypergolic propellants

Ignition delay is one of the most important parameters characterising hypergolic propellants. This parameter has a strong im-pact on thruster operation, especially during the cold start. Ignition delay influences the intensity of pressure rise and its peak values during the start of a thruster. High-pressure levels cause stress inside the chamber wall, which directly affects durability and safety. One of two measurement techniques is usually chosen to determine the ignition delay: visual and pressure-based methods. Visual methods are based on high-speed imaging and subsequent image analysis. In the pressure-based method, the pressure trace is analysed. In this study, both techniques were used together and compared in terms of ignition delay determination of hypergolic propellants igniting during the drop tests. The advantages and disadvantages of both techniques were indicated and described. In the setup used in the study, the visual method was found to be more accurate and reliable.

Exploring the State of Mental Well-Being Among B40 Women

The solution projects under The All-Party Parliamentary Group Malaysia on the Sustainable Development Goals (APPGM-SDG) have played a significant role in empowering the local communities, particularly women through Income Generation (IG) and Community Learning Center (CLC) projects. The initiative consists of twelve modules on entrepreneurship skills and handholding, with a minimum of 10 to 25 beneficiaries from the B40 category who are mentored by the Solution Provider (SP) throughout the following three to four months. Each project was awarded a RM40,000 grant to provide the beneficiaries with skills and knowledge that will allow them to be independent entrepreneurs. It was discovered through the four case studies that adhered to SDG 1 (No Poverty) and SDG 3 (Good Health and Well-Being) that certain female beneficiaries were experiencing such high levels of life pressure that negatively impacted their mental health due to a lack of necessary coping strategies to manage the stress and uncomfortable emotions. The reasons vary, ranging from personal issues and societal pressures to the inherent challenges of entrepreneurship. The finding shows that the project’s method of group activities or social groups enhances the beneficiaries’ mental health by providing them with encouragement, hope, and drive to succeed in life. It is also highly recommended to provide mental health awareness as one of the compulsory modules in the solution projects to equip women with appropriate coping techniques for overall success.

Inertial flow-induced fluid pressurization enhances the reactivation of rate-and-state faults

We reveal that inertial flow can introduce additional pressure perturbations which accelerate the instability of critically stressed faults. We integrate a poroelastic spring-slider model with rate-and-state friction (RSF), a nonlinear flow model characterized by the improved Izbash equation, and a universal visco-inertial permeability model. The effect of inertial flow depends on the fracture network properties, proximity to faults, and injection parameters. Significant inertial flow results in higher pressure magnitudes and pressurization rates, causing notable differences in predictions between linear and nonlinear flow models, as well as aging and slip laws. The impact of inertial flow is particularly pronounced within a specific permeability range and is enhanced by high-rate injections. The fault reactivation is delayed due to fault strengthening with RSF in response to increased pressurization rates. Conversely, the presence of inertial flow enhances fault reactivation and promotes unstable slip behaviors. Furthermore, the results demonstrate that cyclic injection increases the critical stiffness of faults without an adequate release of pore pressure in each cycle. The time interval of the cyclic injection is prolonged as inertial flow generates higher pressure levels. This study highlights the importance of inertial flow in the stability analysis of critically stressed faults.

Integrated metabolomics analysis of chill-stored rose shrimp (Parapenaeus longirostris) treated with different pressure levels of high hydrostatic pressure by 1H-NMR spectroscopy.

The antimicrobial effects of high hydrostatic pressure (HHP) treatments on chill-stored seafood are well-documented, while their impact on the metabolic profile of seafood, especially the metabolome of fish flesh, and remains underexplored. Addressing this gap, this study investigates the effects of HHP on the metabolome of chill-stored rose shrimp by conducting multivariate data analysis based on untargeted proton nuclear magnetic resonance observations. Vacuum-packed rose shrimp samples were subjected to HHP at 0, 400, 500, and 600MPa for 10 min and then stored at 2-4°C. The microorganism analysis and metabolic analysis were carried out on days 1 and 14. HHP treatment effectively deactivated Lactobacillus spp., Escherichia coli, Pseudomonas spp., total Coliforms, and sulfite-reducing anaerobic bacteria. Consequently, HHP treatment significantly reduced the formation rate of decay-related metabolites, such as hypoxanthine, trimethylamine, and biogenic amines, which exhibited significant accumulation in untreated samples. Multivariate unsupervised analyses provided insights into the overall changes in the metabolite profile induced by HHP. Metabolic pathway analysis revealed several pathways underlying spoilage, including pyruvate metabolism, valine, leucine, and isoleucine biosynthesis, purine metabolism, methane metabolism, glycine, serine, and threonine metabolism, citrate cycle (TCA cycle), glycolysis/gluconeogenesis, alanine, aspartate, and glutamate metabolism, sulfur metabolism, pantothenate and CoA biosynthesis, glutathione metabolism, and glyoxylate and dicarboxylate metabolism. Importantly, these pathways underwent alterations due to the application of HHP, particularly at high-pressure levels. In summary, the results unveil the potential mechanisms of HHP effects on chill-stored rose shrimps.

Modelling the Relationship between Water Jetting Parameters and Material Failure in Heat Exchanger Tubes

The Zeeland-Flemish region has a robust process industry where heat exchangers (HEX) are essential for managing heat transfer. However, Fouling in HEX occurs when deposits of contaminants form on surfaces affecting heat transfer. HEX maintenance/cleaning can harm the material of construction (MoC). This study explores how altering Water Jetting (WJ) parameters affects MoC failure mechanisms. This knowledge can optimize processes to prevent unwanted MoC failure while achieving desired fouling control. In this study, a three-factorial experiment was designed to investigate how increased water pressure and flow rates impact the structural health of copper used in HEX tubes during WJ cleaning. Then, we compared these results with experiments using steel as the MoC. Statistical and mathematical analysis were employed to understand the effect of process parameters on damage mechanisms and identify the most influential parameter. For copper samples, we observed that higher water pressure consistently increased damage across all flow rates, following a linear trend of α_p =0.001(gm loss/gm sample. Kpsi). Flow rate's impact on damage exhibited logarithmic behavior, which can be split into two ranges. At low to medium flow levels, increased flow rates raised damage at a rate of α_f =0.007(gm loss/gm sample. gpm). However, at high flow rates, the increase in flow had no effect on the damage as it was attributed solely to pressure. Comparing steel and copper at high pressure levels, it was found that steel experienced a lower linear increase in damage, β_f =0.0036(gm loss/gm sample. gpm), compared to α_f for copper. These results offer insights for optimizing water jetting cleaning processes to minimize material damage during HEX maintenance, enhancing overall efficiency.

Characterization of high-pressure-treated Bacillus subtilis spore populations using flow cytometry — Shedding light on spore superdormancy at 550 MPa

Mild spore inactivation can be challenging in industry because of the remarkable resistance of bacterial spores. High pressure (HP) can trigger spore germination, which reduces the spore's resistance, and thereby allows mild spore inactivation. However, spore germination is heterogenous. Some slowly germinating or non-germinating spores called superdormant spores remain resistant and can survive. Therefore, superdormant spores need to be characterized to understand the causes of their germination deficiency.Bacillus subtilis spores were pressurized for 50 s – 6 min at a very high pressure (vHP) level of 550 MPa and 60 °C in buffer to trigger germination. For a rapid quantification of the remaining ungerminated superdormant spores, flow cytometry (FCM) analysis was validated using single cell sorting and growth analysis. FCM based on propidium iodide (PI) and SYTO16 can be used for 550 MPa-superdormant spores after short vHP treatments of ≤1 min and post-HP incubation at 37 °C or 60 °C. The need for a post-HP incubation is particular for vHP treatments. The incubation was successful to separate FCM signals from superdormant and germinated spores, thus allowing superdormant spore quantification. The SYTO16 and PI fluorescence levels did not necessarily indicate superdormancy or apparent viability. This highlights the general need for FCM validation for different HP treatment conditions.The ∼7 % of ungerminated, i.e., superdormant, spores were isolated after a vHP treatment (550 MPa, 60 °C, 43–52 s). This allowed the characterization of vHP superdormant spores for the first time. The superdormant spores had a similar dipicolinic acid content as spores of the initial dormant population. Descendants of superdormant spores had a normal vHP germination capacity. The causes of vHP superdormancy were thus unlikely linked to the dipicolinic acid content or a permanent genetic change. Isolated superdormant spores germinated better in a second vHP treatment compared to the initial spore population. This has not been observed for other germination stimuli so far. In addition, the germination capacity of the initial spore population was time-dependent. A vHP germination deficiency can therefore be lost over time and seems to be caused by transient factors. Permanent cellular properties played a minor role as causes of superdormancy under chosen HP treatment conditions.The study gained new fundamental insights in vHP superdormancy which are of applied interest. Understanding superdormancy helps to efficiently develop a strategy to avoid superdormant spores and hence to inactivate all spores. The development of a mild HP spore germination-inactivation process aims at better preserving the food quality.

Subacute behavior of glucose and blood pressure of type 1 diabetic people after strength exercise session: Study protocol

Background: Type 1 Diabetes Mellitus (DM1) is characterized as a severe insulin deficiency resulting from the destruction of beta cells in the pancreas, associated with autoimmunity. The clinical picture of a patient with DM1 includes symptoms such as abnormal thirst, dry mouth, sudden weight loss, frequent urination, lack of energy, tiredness, constant hunger and blurred vision. Systemic arterial hypertension (SAH) is characterized by high levels of pressure in the arteries, being associated with risk factors for coronary artery disease; cerebrovascular accident (CVA); myocardial infarction; heart failure and kidney failure. Regular physical activity in these patients is associated with a reduced risk of future cardiovascular disease, better long-term glycemic control, better cardiovascular fitness, better quality of life, reduced daily insulin requirements and better weight control. Furthermore, it plays an important role in the primary and secondary prevention of diabetes cardiovascular disease, improving general health and well-being. Objective: The present study aims to evaluate the effects of strength training on glycemic parameters after an exercise session, in adult type 1 diabetic individuals, through a randomized controlled clinical trial. Methodology: The sample will be made up of 30 participants with DM1, made up of men and women based on the inclusion/exclusion criteria. Discussion: Practicing physical activity reduces the need for hypoglycemic drugs, also improves metabolic control and helps obese patients lose weight, reducing the risk of cardiovascular diseases and improving the quality of life of these patients. The practice of strength and aerobic training as a non-drug treatment is systematically found in the literature as a fundamental strategy for reducing systemic arterial hypertension and maintaining the cardiovascular system. Both resistance exercise and Pilates are effective for individuals with type 1 diabetes, improving metabolic and clinical control, especially when combined with adequate nutrition and amino acid supplementation. Physical activities reduce the need for hypoglycemic medications, help with weight loss and reduce the risk of cardiovascular diseases. Regular exercise, especially intermittent, significantly reduces the risk of acute hypoglycemia. Furthermore, it improves HDL and LDL levels, essential for reducing cardiovascular risks. Strength and aerobic training are essential for controlling high blood pressure and improving quality of life, with three weekly sessions being recommended for satisfactory results.

Predictive Ability of Self-Care and Psychological Flow in Occupational Stress Among Nurses

Background The nursing workforce is crucial in healthcare systems worldwide and contributes to community well-being. also, Nurses experience numerous psychological, social, emotional, and behavioral shocks and challenges in their work. In Jordan, 43% of doctors and nurses suffer from high levels of burnout, around 55% experience high levels of emotional exhaustion, and 33% of doctors and nurses suffer from high levels of psychological pressure and job stress. Others found that 70% of nurses experience stress. these issues can be reduced by practicing self-care and psychological flow which impact in work-related tasks which are important in effectively addressing occupational stress healthily and soundly. This study aims to determine predictive ability of self-care and psychological flow in occupational stress among nurses Methods This study follows the quantitative technique. sample consisting of 476 nurses in Amman Jordan was chosen. Three scales were developed to meet the study objectives: Occupational stress scale, Self-care scale, and psychological flow scale. Results The study results indicate that self-care and psychological flow levels were low, while the occupational stress level was high. Also, there are a predictive ability of self-care and psychological flow in occupational stress among nurses. Conclusions This study shows that of self-care and psychological flow predict occupational stress among nurses, which helps us to manage the occupational stress among them by giving them self-care and psychological flow practices and healing time.