Adolescents’ mental health and well-being is a public health concern. We examined gender differences in stress, psychological distress and well-being and predictors of distress and well-being in adolescent boys and girls. A cross-sectional study with a sample of 954 Spanish adolescents aged between 13 and 17 years was conducted. All participants were assessed through questionnaires that measure psychological distress, eudaimonic well-being, life satisfaction, stress, coping styles, masculine/instrumental and feminine/expressive traits, self-esteem and social support. We find that girls scored higher than boys in psychological distress, chronic stress, minor daily hassles, social support, eudaimonic well-being and in feminine-expressive trait whereas boys scored higher than girls in detachment coping style and in masculine-instrumental trait. Hierarchical multiple regression analysis revealed that the most relevant variable in the psychological distress of both girls and boys was higher emotional coping style, followed by higher number of life events during the previous year. The most relevant variables in boys’ and girls’ psychological well-being were higher self-esteem and social support. Higher scores in rational coping style and in masculine/instrumental trait were also important predictors of eudaimonic well-being in adolescent boys and girls. Furthermore, in boys, older age was associated with greater distress and lower well-being and life satisfaction, while, as for the girls, a smaller number of life events and greater emotional coping style were associated with lower eudaimonic well-being and life satisfaction. Results are relevant for the design of policies and programs aimed at promoting mental health and well-being in adolescence.
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