This study aims to determine the effect of physiography based on slope and land cover for water control in Kali Lamong watershed. The data used in this research are DEM data and Landsat 8 imagery data. The process of processing slope data is through conversion coordinates system, DEM clip, create slope, reclassify, dissolve shapefile, and slope classification analysis. Landsat 8 data processing goes through a process through conversion coordinates system, composite band, crop composite, extent shapefile, sharpen band, unsupervised classification, and land cover classification analysis. Slope classification maps and land cover classification maps are used for flow coefficient classification for physiographic analysis based on slope and land cover for water control in Kali Lamong watershed. On the land cover classification map, five land classifications were obtained, namely agriculture (158413000 m2), settlements (72701400 m2), industrial land (11571600 m2), plantations (46017800 m2), and waters (15268500 m2). On the slope classification map obtained 5 classifications, as flat with a slope of 0-8% (288469544 m2), as slope with a slope of 8-15% (7656738 m2), as rather steep with a slope of 15-25% (1905360 m2), as steep with a slope of 25-45 (526614 m2), and as very steep with a slope of more than 45% (32148 m2). From the combination of Landsat 8 image data and slope data, flow coefficient analysis was carried out. The flow coefficient is influenced by land cover and slope. From this research, the classification of low flow coefficient is less than 0.25, medium flow coefficient is 0.25-0.5, and high flow coefficient is more than 0.75. The average flow coefficient of Kali Lamong watershed is 0.49 with a moderate flow coefficient classification value. This shows that 49% of the runoff water is in Kali Lamong watershed. The higher the flow coefficient value, the water runs off the surface. So that it can be used as an initial study for the technical planning of Kali Lamong hydrology and the development, improvement, utilization, and control of water flow in Kali Lamong.