Background: COVID-19 impacted higher education (HE) students studying health degrees with an embedded placement in a unique way. At the height of the pandemic AHPRA declared that health students completing placements were required to be vaccinated against COVID-19 and be competent at providing advice and information about the COVID-19 vaccine to the public. It is yet to be determined if there is hesitancy amongst students studying health degrees. This study aimed to determine if offering an evidence-based targeted educational intervention changes health student knowledge, attitudes, and willingness to have the vaccine. Methods: An evidence-based educational intervention was developed and delivered to students studying health. A purpose developed survey was designed to assess health students’ knowledge, and willingness to have the COVID-19 vaccine, before and after this targeted educational intervention. Results: A total of 290 students from eight health disciplines completed the intervention and pre- and post-surveys. Analyses demonstrated a statistically significant increase in participants’ willingness to receive the COVID-19 vaccine, and how confident participants felt about explaining Covid vaccines and their safety, with an increase in accuracy of knowledge about professional responsibility. Conclusion: This study shows that targeted educational intervention can positively influence HE health care students. Increasing the knowledge and confidence of our trainee health professionals is paramount to enable them to be sources of accurate information and advice in relation to Covid vaccination.