Higher Depression Scale Scores Research Articles

Incidence and multidimensional predictors of occasional and recurrent falls among Malaysian community\u2010dwelling older persons

BackgroundFalls incidence rate and comprehensive data on factors that predict occasional and repeated falls from large population-based studies are scarce. In this study, we aimed to determine the incidence of falls and identify predictors of occasional and recurrent falls. This was done in the social, medical, physical, nutritional, biochemical, cognitive dimensions among community-dwelling older Malaysians.Methods Data from 1,763 Malaysian community-dwelling older persons aged ≥ 60 years were obtained from the LRGS-TUA longitudinal study. Participants were categorized into three groups according to the presence of a single fall (occasional fallers), ≥two falls (recurrent fallers), or absence of falls (non-fallers) at an 18-month follow-up.ResultsThree hundred and nine (17.53 %) participants reported fall occurrences at an 18-month follow-up, of whom 85 (27.51 %) had two or more falls. The incidence rate for occasional and recurrent falls was 8.47 and 3.21 per 100 person-years, respectively. Following multifactorial adjustments, being female (OR: 1.57; 95 % CI: 1.04–2.36), being single (OR: 5.31; 95 % CI: 3.36–37.48), having history of fall (OR: 1.86; 95 % CI: 1.19–2.92) higher depression scale score (OR: 1.10; 95 % CI: 1.02–1.20), lower hemoglobin levels (OR: 0.90; 95 % CI: 0.81-1.00) and lower chair stand test score (OR: 0.93; 95 % CI: 0.87-1.00) remained independent predictors of occasional falls. While, having history of falls (OR: 2.74; 95 % CI: 1.45–5.19), being a stroke survivor (OR: 8.57; 95 % CI: 2.12–34.65), higher percentage of body fat (OR: 1.04; 95 % CI: 1.01–1.08) and lower chair stand test score (OR: 0.87; 95 % CI: 0.77–0.97) appeared as recurrent falls predictors.ConclusionsHaving history of falls and lower muscle strength were predictors for both occasional and recurrent falls among Malaysian community-dwelling older persons. Modifying these predictors may be beneficial in falls prevention and management strategies among older persons.

Periodontal disease and emotional disorders: A meta-analysis.

The objective of this study was to evaluate the relationship of periodontal disease with depression and anxiety via a systematic review and meta-analysis. We systematically searched the EMBASE, PubMed, Web of Science, PsycINFO, and SinoMed databases (until August 4, 2019) with language restricted to English and Chinese. Case-control, cross-sectional, and cohort studies that calculated the risk ratio (RR), odds ratio (OR)/prevalence OR (POR), and hazard ratio (HR) of depression/anxiety with periodontal disease or the OR/POR/RR/HR of periodontal disease caused by depression/anxiety were included. Observational studies that reported the depression/anxiety scale score of patients with periodontal disease and healthy periodontal subjects aged ≥14years were also included. We used the standard format to extract the following information from each included study: author/s, survey year, study design, age of participants, periodontal disease definition, depression/anxiety measurement, and summary of results. The Newcastle-Ottawa scale was used to ascertain the quality of the included citations. After screening, 40 studies were included. A meta-analysis of the case-control studies showed that periodontal disease was positively associated with depression (OR=1.70, 95% confidence interval [CI] =1.01-2.83). A meta-analysis of 12 studies showed that periodontal disease was significantly correlated with anxiety (OR=1.36, 95% CI=1.11-1.66). A meta-analysis of 18 studies showed that subjects with periodontal disease had higher depression scale score (standardized mean difference [SMD]=1.05, 95% CI=0.68-1.41) and anxiety scale score (SMD=0.70, 95% CI=0.44-0.96). Periodontal disease is associated with emotional disorders. However, the high degree of heterogeneity among studies should be considered. More high-quality prospective studies are required to confirm the relationship.

Alterations in internetwork functional connectivity in patients with chronic migraine within the boundaries of the Triple Network Model

AbstractBackgroundAlterations in large‐scale functional connectivity have widely been used to understand migraine pathophysiology and to find any imaging markers. The successful use of the Triple Network Model for many mental and neurological diseases has prompted us to consider chronic migraine under the prism of this model for the first time in the literature.AimTo evaluate alterations in functional connectivity between large‐scale networks using resting‐state fMRI in chronic migraine patients and their correlation with clinical features within the boundaries of the Triple Network Model.MethodsTwenty‐five chronic migraine patients underwent 1,5T resting‐state functional magnetic resonance imaging (RS‐fMRI) scanning during the interictal phase and were compared to a group of 25 healthy controls. Functional connectivity was assessed using region‐of‐interest to region‐of‐interest (ROI‐to‐ROI) analysis between 8 networks and 15 subcortical areas, conventionally assigned to salience network.ResultsCompare to healthy controls, patients had increased functional connectivity between salience network (SN) and sensorimotor network (SMN) and dorsal attention network (DAN), between nucleus accumbens and default mode network (DMN) and within DMN and also between thalamus and DAN. Decreased functional connectivity was registered between nucleus accumbens and DAN, and also within DAN. A higher depression scale score was positively correlated with an increase in FC within DMN.ConclusionTaken together, our results show that patients with chronic migraine could be characterized by specific dysfunctional interactions between the SN, SMN, DAN, and DMN during resting state.

A Cross-Sectional Study Assessing Depression and Associated Healthcare Barriers among Urban Pakistani Women

Background: Few studies have assessed depression amongst Pakistani women, particularly in more upscale communities where many traditional risk factors for depression and associated treatment are greatly reduced. Therefore, this study sought to examine depression prevalence in a highly developed sector of Islamabad, factors associated with depression, and the association between depression and barriers to accessing healthcare. Subjects and Method: In 2016, a cross-sectional pilot study was conducted in Islamabad using convenience sampling. The survey design was based on the Pakistan Demographic Health Survey and included the Center for Epidemiological Studies Depression (CESD) scale. 93 women filled out the entire questionnaire. Results: The prevalence of depression was unanticipated at 78%; 53% of these women sampled had major depression. 22% of women reported ever having spoken to a provider about their mental health. 41% of women further reported that their mental health negatively impacted their decision to receive care. The only independent risk factor for depression was the diagnosis of another disease. Indicators of poor-socioeconomic status, however, were consistently associated with higher depression likelihood. A robust multivariable regression analysis showed an association between a higher number of self-reported barriers to accessing care and higher depression scale scores (p<0.05). Conclusion: A high burden of untreated depression likely exists amongst Pakistani women from urban regions despite a relatively higher prevalence of healthcare resources. Improving mental health disparities in urban settings throughout Southwest and South Asia will require not only increased screening and treatment of patients, but also removal of physical and psychological barriers faced in accessing care. Keywords: mental health, access barrier, women’s health, health equity Correspondence: Marina Haque. Office for Health Equity and Inclusion at the School of Medicine and Department of Health Management and Policy at the School of Public Health, University of Michigan 5101 Medical Sciences I Building 22535 Fuller Drive, Novi, MI 48374 USA. Email: Marinaha@umich.edu. Mobile: + 1 (248) 767 3096. Journal of Epidemiology and Public Health (2020), 05(02): 168-181 https://doi.org/10.26911/jepublichealth.2020.05.02.05

Psychopathological and sociodemographic features in treatment-resistant unipolar depression versus bipolar depression: a comparative study

BackgroundSome authors have hypothesized that Treatment-Resistant Unipolar Depression (TRD-UP) should be considered within the bipolar spectrum disorders and that hidden bipolarity may be a risk factor for TRD-UP. However, there are neither studies comparing clinical and sociodemographic data of patients with TRD-UP versus Bipolar (BP) disorders nor are there any examining differences versus Bipolar type I (BP-I) and Bipolar type II (BP-II).MethodsCharts analysis was conducted on 194 patients followed at the Mood Disorders Clinic of the McGill University Health Center. Sociodemographic, clinical features and depression scales were collected from patients meeting DSM-IV criteria for TRD-UP (n = 100) and BP (n = 94). Binary logistic regression analysis was conducted to examine clinical predictors independently associated with the two disorders.ResultsCompared to BP, TRD-UP patients exhibited greater severity of depression, prevalence of anxiety and panic disorders, melancholic features, Cluster-C personality disorders, later onset of depression and fewer hospitalizations. Binary logistic regression indicated that higher comorbidity with anxiety disorders, higher depression scale scores and lower global assessment of functioning (GAF) scores, and lower number of hospitalizations and psychotherapies differentiated TRD-UP from BP patients. We also found that the rate of unemployment and the number of hospitalizations for depression was higher in BP-I than in BP-II, while the rate of suicide attempts was lower in BP-I than in BP-II depressed patients.ConclusionsThese results suggest that TRD-UP constitutes a distinct psychopathological condition and not necessarily a prodromal state of BP depression.

Tobacco product use and mental health status among young adults

BackgroundIndividuals with mental health conditions represent a priority population for tobacco control. This population smokes cigarettes at disproportionately higher rates than the general population, but less is known about the relationship between non-cigarette tobacco use and mental health status. MethodIn 2013, 2370 young adults recruited from 11 colleges in North Carolina and Virginia completed an online survey on tobacco use. We compared past 6-month self-reported mental health diagnosis, past 30-day depression score, and past 7-day stress score to past 30-day cigarette, e-cigarette, waterpipe, cigar, and smokeless tobacco use. Models adjusted for age, gender, race, ethnicity, and mother's education. Non-cigarette products were also adjusted for past 30-day cigarette use. ResultsAmong participants, 249 (10.5%) reported a mental health diagnosis, most commonly depression (5.5%), ADHD/ADD (4.5%), and anxiety (0.8%). Those who reported a mental health diagnosis had greater odds of using cigarettes (AOR=1.55; CI=1.01, 2.27). Mean stress score was 16.0 (SD=6.9) of possible 40. Higher stress scale score was associated with increased odds of e-cigarette (AOR=1.03; CI=1.01, 1.05), waterpipe (AOR=1.04; CI=1.01, 1.06), and cigarette (AOR=1.02; CI=1.00, 1.04) use. Mean depression score was 7.2 (SD=5.6) of possible 33. Higher depression scale score was associated with increased odds for e-cigarette (AOR=1.04; CI=1.01, 1.08) and cigarette (AOR=1.03; CI=1.01, 1.06) use. ConclusionFindings in this study provide further evidence of a potential relationship between non-cigarette tobacco products and mental health status. Tobacco control efforts aimed at reducing tobacco use disparities among mental health populations should focus on non-cigarette tobacco products in addition to cigarettes.

Stress-related hemodynamic response in healthy young individuals with Type D personality

Aim. To investigate the association between the stress-related hemodynamic response during the mental calculation test (MCT) and the presence of Type D personality in healthy young individuals. Material and methods. The study included 80 healthy individuals (19 men and 61 women; mean age 18,8±0,2 years). Psychological status examination included the DS-14 scale, depression scale, and Spielberger-Khanin scale. MCT was performed with simultaneous assessment of hemodynamic response. Results. Type D personality (distressed type) was observed in 32,5% of the participants. Among young students, Type D personality was associated with higher levels of trait and state anxiety (TA and SA), as well as higher depression scale scores, compared to students without Type D personality. Type D personality was also linked to a more pronounced response of systolic blood pressure (SBP) during MCT (p=0,05). There was a strong correlation between social inhibition levels and maximal heart rate (HR) during MCT (r=-0,238; p=0,034). Young men demonstrated a moderate correlation between Type D personality and HR response (r=-0,508; p=0,026), as well as between negative affectivity levels and HR response during MCT (r=0,469; p=0,043). Conclusion. Distressed personality type was observed in one-third of healthy young participants of the study. Type D personality and its subscales correlated with the hemodynamic response during MCT, with some gender-specific features observed. These findings clarify potential mechanisms of Type D personality effects on the development and prognosis of cardiovascular disease.

1206 Sustained viral response during HCV treatment is associated with higher depression scale scores

1206 Sustained viral response during HCV treatment is associated with higher depression scale scores

Predictors of Patient Inability to Cooperate during Intraoperative Language Mapping

We examined the demographic, seizure history, personality, and intellectual variables in seizure surgery patients who underwent intraoperative language mapping to identify variables that may help predict inability to cooperate with intraoperative mapping. Of 26 patients who had intraoperative language testing during left hemisphere lobectomy, 9 were unable to cooperate with language mapping procedures. Mapping “failure” consisted of an inability to conform to task demands due to anxiety, inattention, immaturity, or confusion that necessitated changing from local to general endotracheal anesthesia. Patients who were unable to cooperate with intraoperative mapping had significantly lower IQs, lower educational attainment, and higher Depression scale scores on the Minnesota Multiphasic Personality Inventory (MMPI) relative to cooperative patients. There were no statistically significant differences between groups with respect to age, handedness, sex, age of onset of habitual seizures, seizure type, site of seizure focus, presence of a lesion, or previous psychiatric history.