This study evaluates flood susceptibility and risk on Bulk Supply Points in the Greater Accra region (GAR) using a Frequency Ratio model based on 15 flood conditioning factors. The model explores the influence of natural, meteorological and anthropogenic factors on flooding occurrences under the Shared Socioeconomic Pathway (SSP) scenarios and assesses flood risks at Bulk Supply Points (BSPs). Flood susceptibility mapping was conducted for both current and future periods under various SSP scenarios. Results reveal that elevation, slope, soil type, distance from urban areas, and SPI are the most influential factors contributing to flooding susceptibility in the region. The current flood map, about 37% of the total area of GAR categorized under the moderate flood-susceptible zone category followed by about 30% categorized under the low flood-vulnerable zone. However, about 16% was categorized under the very high flood-vulnerable zone. The study projects increasing flood susceptibility under the SSP scenarios with intensification under SSP2 and SSP3 scenarios. For instance, the areas categorized as high and very high flood susceptibility zones are projected to expand to approximately 32% and 26% each by 2055 under SSP3. The study also assesses flood risks at Bulk Supply Points (BSPs), highlighting the escalating susceptibility of power assets to flooding under different scenarios. For instance, in the very high scenario, flooding is estimated to reach 640 h in 2045 and exceed 800 h in 2055—more than double the 2020 baseline. The analysis shows the bulk supply points face increasing flood susceptibility, with risks escalating most sharply under the severe climate change SSP3 and SSP5 scenarios. Over 75% of BSPs are expected to fall in the low- to medium-risk categories across SSPs while more than 50% of BSPs are within medium- to high-risk categories in all scenarios except SSP1, reflecting the impact of climate change. SSP3 and SSP5 stand out with over 60% of BSPs facing high or very high flooding risks by 2055. It indicates moderate resilience with proper adaptation but highlights potential disruptions in critical infrastructure, such as BSPs, during persistent flooding. The findings of the study are expected to inform Ghana’s contributions towards addressing Sustainable Development Goals (SDGs) 7, 11 and 13 in Ghana.