The observed rest-UV luminosity function at cosmic dawn (z ∼ 8–14) measured by JWST revealed an excess of UV-luminous galaxies relative to many prelaunch theoretical predictions. A high star formation efficiency (SFE) and a top-heavy initial mass function (IMF) are among the mechanisms proposed for explaining this excess. Although a top-heavy IMF has been proposed for its ability to increase the light-to-mass ratio (ΨUV), the resulting enhanced radiative pressure from young stars could decrease the SFE, potentially driving galaxy luminosities back down. In this Letter, we use idealized radiation hydrodynamic simulations of star cluster formation to explore the effects of a top-heavy IMF on the SFE of clouds typical of the high-pressure conditions found at these redshifts. We find that the SFE in star clusters with solar-neighborhood-like dust abundance decreases with increasingly top-heavy IMFs—by ∼20% for an increase of a factor of 4 in ΨUV and by 50% for a factor of ∼10 in ΨUV. However, we find that an expected decrease in the dust-to-gas ratio (∼0.01 × solar) at these redshifts can completely compensate for the enhanced light output. This leads to a (cloud-scale; ∼10 pc) SFE that is ≳70% even for a factor of 10 increase in ΨUV, implying that highly efficient star formation is unavoidable for high surface density and low-metallicity conditions. Our results suggest that a top-heavy IMF, if present, likely coexists with efficient star formation in these galaxies.