Higher Quality Of Life Scores Research Articles

Effect of Rehabilitation Nursing Intervention on the Quality of Life of Neurological Patients with Cerebral Hemorrhage Sequelae

Objective: To analyze the effect of rehabilitation nursing intervention on the quality of life of neurological patients with sequelae of cerebral hemorrhage. Methods: 70 patients with cerebral hemorrhage and sequelae who were admitted to the hospital from February 2022 to February 2024 were randomly divided into the observation group and the control group, and were subjected to conventional nursing measures and rehabilitation nursing intervention modes respectively to analyze the effects of the interventions in the two groups. Results: After the intervention, the observation group had lower nerve damage, stronger independent self-care ability, and better recovery of limb function, P < 0.05. After the intervention, the observation group had higher quality of life scores, and lower probability of complications, P < 0.05. Conclusion: the neurology department involves relatively more patients with cardiovascular and cerebrovascular diseases, and the presence of cerebral hemorrhage in the patients may lead to several sequelae, which will affect the daily lives of the patients. The implementation of rehabilitation nursing interventions can improve the recovery rate of patients’ neurological function and limb function, improve patients’ self-care ability, and maintain patients’ quality of life.

An evidence-based nursing practice affects stress state, coagulation, complications and quality of life in patients with upper gastrointestinal bleeding in the emergency department: a retrospective observational study

BackgroundAcute gastrointestinal bleeding (GIB) is a common surgical emergency digestive system disorder with high morbidity and mortality.AimThis study sought to explore effects of evidence-based nursing practice (ENP) procedures on stress state, coagulation function, complications in patients with upper GIB (UGIB) and quantify of life in emergency department.MethodsThis study was a retrospective analysis and a total of 120 patients with UGIB were enrolled and divided into an experimental group with ENP interventions and a reference group with traditional nursing according to different nursing programs. The physiological stress indicators (epinephrine, norepinephrine, plasma cortisol), psychological stress indicators [anxiety self-assessment scale (SAS), depression self-assessment scale (SDS)], coagulation function indicators [prothrombin time (PT), prothrombin time (TT), D-dimer (D-D), fibrinogen (FIB)], complication rate and quality of life were analyzed.ResultsAfter nursing intervention, epinephrine, norepinephrine and plasma cortisol, SDS and SAS scores were decreased in the experimental group relative to the reference group (all P < 0.001). After nursing intervention, the levels of PT, TT and D-D in both groups were lower and the FIB was higher than before intervention (all P < 0.001), and the improvement of coagulation function indexes in experimental group after nursing was better than that in reference group (P < 0.001). The incidence of complications in the experimental group was lower than that in the reference group (P = 0.04). The higher quality of life scores after nursing intervention was validated in the experimental group relative to the reference group (P < 0.001).ConclusionENP improved stress response, coagulation function, quality of life, and reduced incidence of complications in UGIB patients, indicating potential for clinical application.

Restless legs syndrome in multiple sclerosis: uncovering prevalence and clinical aspects.

The aim of the study is to determine the prevalence of restless legs syndrome (RLS) in patients with relapsing-remitting multiple sclerosis (RRMS) and explore its associations with sleep quality, comorbidities and quality of life. RLS and RRMS diagnosis were made using the latest criteria the International Classification of Sleep Disorders-3 (ICSD-3) criteria and 2017 McDonald criteria. A total of 210 individuals, including 105 patients diagnosed with RRMS and 105 healthy volunteers were included into the study. Data of demographical and disease characteristics and RLS properties were collected. Several scales to assess anxiety, depression, fatigue, sleep quality and quality of life scales were used. RLS prevalence was found in 21.9% of RRMS patients and 12.4%of healthy volunteers. RRMS patients with RLS exhibit significantly higher anxiety and depression scores in sleep quality, fatigue and quality of life compared to the patients without RLS. This study highlights a higher prevalence of RLS in patients with RRMS compared to healthy individuals. RRMS patients with RLS exhibited distinct characteristics, including lower sleep quality and higher quality of life scores while RLS was nod significantly associated with demographic or clinical variables. Recognizing RLS in patients with RRMS is important for the treatment and improving their overall well-being.

Parenting with nutrition education and unconditional cash reduce maternal depressive symptoms and improve quality of life: findings from a cluster randomised controlled trial in urban Bangladesh

ABSTRACT Background Maternal post-natal depression is a global public health problem. Parenting interventions targeting children’s development may also bring benefits to mothers, but few parenting interventions have been studied thoroughly. Objectives The study aimed to measure the effect of a parenting intervention using culturally appropriate and locally made toys, along with nutrition education and unconditional cash, on maternal depressive symptoms (MDS) and quality of life (QoL). Methods The study was a cluster randomised controlled trial with two arms: i) intervention: parenting with nutrition education and unconditional cash and ii) comparison: unconditional cash in an urban setting in Bangladesh. Twenty clusters were randomised to either the intervention or control group. Community Health Workers (CHWs) delivered parenting and nutrition education sessions fortnightly in households for one year. The participants were mother-child (6–16 months) dyads. The MDS and QoL were measured using the Self-Reporting Questionnaire-20 and a brief version of the QoL questionnaire. Linear regression analysis was used to assess the treatment effects. Results After one year of intervention, 547 mothers (93%) completed the study. The mothers in the intervention group had lower MDS [Regression coefficient (β)=-1.53, Confidence interval (95% CI)=-2.28, −0.80] and higher QoL scores in physical health [β = 4.21 (95% CI = 1.71, 6.73)], psychological health [β = 3.14 (95% CI = 1.10, 5.19)], social relationships [β = 3.21 (95% CI = 0.76, 5.66)] and environment [β = 3.40 (95% CI = 1.37, 5.44)] compared with the comparison group. Conclusion Parenting interventions including nutrition education and unconditional cash, aimed at improving children’s development, resulted in a reduction in maternal depressive symptoms and improvement in quality of life.

Patient-Reported Outcomes after Surgical, Endoscopic, or Radiological Techniques for Nutritional Support in Esophageal Cancer Patients: A Systematic Review.

Several techniques exist to maintain oral and/or enteral feeding among esophageal cancer (EC) patients, but their impact on patient-reported outcomes (PROs) remains unclear. This systematic review aimed to assess the impact of nutritional support techniques on PROs in EC patients. We searched Medline, Web of Science, and CINAHL Complete from inception to 3 April 2024. Eligible studies included those evaluating EC patients, reporting PROs using standardized measures, and providing data on different nutritional support techniques or comparing them to no intervention. The reference lists of the included studies were also screened for additional eligible articles. The Mixed Methods Appraisal Tool was used to evaluate the quality of the included studies. Of the 694 articles identified from databases and 224 from backward citation, 11 studies met the inclusion criteria. Nine studies evaluated the overall quality of life (QoL), four assessed pain, and one evaluated depression. Among those submitted to esophagectomy, jejunostomy may be associated with higher QoL scores and less postoperative pain, compared to a nasojejunal tube, but no significant differences were found when compared to no intervention. For patients undergoing chemotherapy or receiving palliative/symptomatic treatment, expandable metal stents (SEMSs) were associated with higher levels of emotional functioning when compared with laparoscopic gastrostomy. Moreover, percutaneous endoscopic gastrostomy or SEMSs were associated with a higher QoL compared with nasogastric tubes. This review underscores the importance of considering PRO measures when evaluating nutritional support techniques in cancer patients, though further robust evidence is needed to fully understand these associations.

Menopause and its impact on the effectiveness of fremanezumab for migraine prophylaxis: post-hoc analysis of a prospective, real-world Greek registry

ABSTRACT Objective This post-hoc analysis of data extracted from a prospective study aimed to explore for the first time if the efficacy of fremanezumab in preventing difficult-to-treat migraine, according to ICHD-III, would differ between pre-menopausal and post-menopausal women. Methods A total of 171 (aged 18–70 years) fremanezumab-treated female migraine patients for six consecutive months were classified to those at pre-menopausal (n = 82) or post-menopausal (n = 89). Monthly headache days (MHD), disability, and quality of life (QOL) outcomes were assessed at baseline and at week 24 post-fremanezumab within subgroups and were then compared between them. Safety and tolerability were also assessed. Results In both groups, fremanezumab demonstrated significant reductions in MHDs, reduced disability, and higher QOL scores at week 24 post-treatment, compared to baseline. However, the between-subgroup comparison documented that pre-menopausal women and those at post-menopausal comparably benefited with significant reductions in overall MHDs (p = 0.883). Less disability, according to MIDAS (p = 0.696) and HIT-6 scores (p = 0.912), as well as higher QOL scores at week 24 post-fremanezumab, were also comparably evident in both groups. Safety was excellent across both subgroups. Conclusion Fremanezumab can be considered a very effective treatment option for preventing migraines in difficult-to-treat women, aged 18–70 years, regardless of their menopausal status.

Association between meeting 24-hour movement behavior guidelines and quality of life in adolescents with idiopathic scoliosis

BackgroundMeeting the 24-hour movement behavior (24-HMB) guideline helps enhance quality of life (QOL) of adolescents. This study aimed to assess the associations between the 24-HMB (physical activity, screen time, sleep) and QOL among adolescents with idiopathic scoliosis.MethodsA cross-sectional study was conducted between September 2021 and September 2023. 24-HMB, QOL and demographic variables were collected through a self-reported questionnaire. Linear regression models and stratified analyses were used to explore statistical associations between the 24-HMB and QOL.ResultsA total of 1073 participants aged 10–18 years with a spinal Cobb angle between 10° and 40° were included. Overall, 20 participants (1.9%) met all three behavioral guidelines, and 272 participants (25.3%) met none. Compared to those who did not meet any of the guidelines, adolescents meeting both screen time and sleep duration (β = 4.10, 95% CI: 2.02–6.18, P < 0.001) and all 3 guidelines (β = 4.39, 95% CI: 0.27–8.51, P = 0.037) had higher QOL scores. Stratified analyses showed that the above associations were more pronounced in adolescents without back pain or with good self-image.ConclusionsThese findings highlight the importance of adopting and maintaining healthy behavioral habits in order to improve QOL among adolescents with idiopathic scoliosis, especially in those without back pain or with good self-image.

The impact of cancer diagnosis on employment status in a working population

The aim of this study was to investigate the status of return to work and the influencing factors in patients with common cancers referring to three medical centers during the years 2020 to 2022. Material and Methods. In the present study (a retrospective cohort), all patients who visited three medical centers during the years 2020–2022 and were diagnosed with common cancers (non-Hodgkin’s lymphoma, Hodgkin’s lymphoma, gastrointestinal cancers and sarcoma), were included in the study. Work ability index (WAI) was assessed based on selected questions from the WAI questionnaire. Hospital Anxiety and Depression Scale (HADS) was used to assess depression and anxiety, and Multidimensional Fatigue Inventory (MFI-20) was used to assess the level of fatigue. Then, the data obtained from individuals who returned to work were compared with those who did not return. Results. Out of 750 eligible patients, 135 individuals were enrolled in the study. 114 patients were male (84.4 %). The mean age of individuals was 50.2 ± 10.4 years. The most of individuals were diagnosed with gastric cancer (n=66, 48.9 %). After treatment, 36 (26.7 %) individuals returned to work, with the majority (24 individuals: 66.6 %) reporting a decrease in physical ability to do work. Sixty-six (73.3 %) patients did not return to work, with the most common reason being physical inability to work in 60 (66.6 %) individuals. Higher quality of life score was reported in individuals who returned to work. Conclusion. The rate of return to work was approximately 27 %. The return to work rate was highest among individuals with non-Hodgkin’s lymphoma and lowest among individuals with oesophageal cancer and Hodgkin’s lymphoma. The most influential factors affecting the return to work include disease recurrence and quality of life.

Quality of Life, Coping Strategies, and Psychosocial Support Status of Caregivers Having Children With Neurodevelopmental Disabilities: A Cross-Sectional Study From Bangladesh.

Background Although caregiving is considered a normal phenomenon for parents, delivering care to a child with neurodevelopmental disabilities can be taxing and disastrously impact parents' quality of life (QoL). This study explored the relationship between QoL, coping strategies, and psychosocial support status of caregivers of children with neurodevelopmental disabilities. Methodology This cross-sectional study included 906 caregivers of children having neurodevelopmental disabilities utilizing the World Health Organization Quality of Life Brief and Perceived Stress Scale. A tailored questionnaire gauged coping strategies and psychosocial support. Linear regression was used to identify significant contributors. Results Most caregivers (78.8%) experienced a moderate level of stress, and their QoL scores were 14.4 (SD = 2.5) for physical health, 12.0 (SD = 2.4) for psychological health, 14.6 (SD = 1.9) for social relationships, and 12.1 (SD = 2.1) for the environment. Mothers had the lowest QoL of all caregivers. Negative influences on QoL encompassed caregiver and child age, perceived stress, and lower socioeconomic status. A higher coping score positively predicted a high health-related QoL score. Gender differences were observed in psychosocial support sources. Conclusions The study underscores the need for policymaking considering findings to develop psychosocial intervention programs for enhancing the QoL of caregivers of children with neurodevelopmental disabilities.

Telemedicine in Pediatric Respiratory Care: Benefits, Challenges, and Future Directions

This study explores the impact of telemedicine on pediatric respiratory care, focusing on its benefits, challenges, and future directions. A mixed-methods approach was employed, involving 150 pediatric patients with chronic respiratory conditions such as asthma and cystic fibrosis, who were randomly assigned to either telemedicine or traditional care groups. The telemedicine group used a digital platform for video consultations, remote monitoring, and health management over a 12-month period. Quantitative data on clinical outcomes, including emergency department visits and hospitalizations, were collected from electronic health records, while patient-reported outcomes were assessed through surveys. Qualitative data were gathered via semi-structured interviews with patients and caregivers. Results indicated that the telemedicine group experienced significantly fewer emergency visits and hospitalizations, higher quality of life scores, better treatment adherence, and greater patient satisfaction compared to the traditional care group. Average oxygen saturation and peak flow rates were also higher in the telemedicine group, and more frequent monitoring alerts were noted.

Information-motivation-behavioral guided nursing for stroke patients with pulmonary dysfunction: A randomized controlled trial

BACKGROUND Patients with stroke frequently experience pulmonary dysfunction. AIM To explore the effects of information-motivation-behavioral (IMB) skills model-based nursing care on pulmonary function, blood gas indices, complication rates, and quality of life (QoL) in stroke patients with pulmonary dysfunction. METHODS We conducted a controlled study involving 120 stroke patients with pulmonary dysfunction. The control group received routine care, whereas the intervention group received IMB-model-based nursing care. Various parameters including pulmonary function, blood gas indices, complication rates, and QoL were assessed before and after the intervention. RESULTS Baseline data of the control and intervention groups were comparable. Post-intervention, the IMB model-based care group showed significant improvements in pulmonary function indicators, forced expiratory volume in 1 sec, forced vital capacity, and peak expiratory flow compared with the control group. Blood gas indices, such as arterial oxygen pressure and arterial oxygen saturation, increased significantly, and arterial carbon dioxide partial. pressure decreased significantly in the IMB model-based care group compared with the control group. The intervention group also had a lower complication rate (6.67% vs 23.33%) and higher QoL scores across all domains than the control group. CONCLUSION IMB model-based nursing care significantly enhanced pulmonary function, improved blood gas indices, reduced complication rates, and improved the QoL of stroke patients with pulmonary dysfunction. Further research is needed to validate these results and to assess the long-term efficacy and broader applicability of the model.

Living the Dream-Housing Perceptions and Quality of Life of Older People Living in Manufactured Home Villages

This study aimed to examine the quality of life (QoL) of manufactured home village (MHV) residents and their perceptions of village life. Surveys of 259 residents aged ≥60 years living in two MHV communities in New South Wales, Australia was undertaken. QoL scores were like that of older people in Australia generally. Residents mostly reported positive perceptions of village life. Higher QoL scores were associated with living with someone and perceptions that village supports were available. Given the housing crisis in Australia and elsewhere, MHVs may be an affordable housing option where older people can enjoy a good QoL.

Effect of information-motivation-behavioral skills model based perioperative nursing on pain in patients with gallstones.

The incidence of cholecystolithiasis is on the rise. Use of information, motivation, and behavioral skills can play a positive role in promoting changes in individual health behaviors. However, reports on the effects of information-motivation-behavioral (IMB) skills model based high-quality nursing as a perioperative nursing intervention for patients with gallstones are nonexistent. To explore the application of IMB skills model based high-quality nursing in patients with gallstones. Two hundred and sixteen patients with cholecystolithiasis treated at our hospital from January 2022 to January 2023 were enrolled and divided into a control, high-quality, and combined nursing groups, with 72 patients in each group. The control, high-quality, and combination groups received conventional, high-quality, and IMB skills model based perioperative nursing services, respectively. Differences in clinical indicators, stress levels, degree of pain, emotional state, and quality of life were observed, and complications and nursing satisfaction among the three groups were evaluated. After nursing, the time to recovery of gastrointestinal function in the high-quality and combined nursing groups was significantly shorter than that of the control group, with the recovery of gastrointestinal function being the fastest in the combined nursing group (P < 0.05). After nursing intervention, cortisol and norepinephrine levels in the high-quality and combined nursing groups were closer to normal than those of the control group 24 h after surgery, with the combined nursing group having the closest to normal levels (P < 0.05). After 3 and 7 d of intervention, the patients' pain significantly improved, which was more prominent in the high-quality and combination groups. Meanwhile, the pain score in the combination group was significantly lower than those of the control and high-quality nursing groups (P < 0.05). After nursing intervention, the emotional states of all patients improved, and the scores of patients in the combination group were significantly lower than those of the control and high-quality nursing groups. The quality of life of patients in the high-quality and combined nursing groups significantly improved after nursing intervention compared to that of the control group, with the combined nursing group having the highest quality of life score. After intervention, the incidence of complications in the high-quality and combination groups was significantly lower than that of the control group (P < 0.05), but the difference between the combination and high-quality nursing groups was not significant. Nursing satisfaction of patients in the high-quality and combination groups was significantly higher than that of the control group, with the nursing satisfaction being the highest in the combination group (P < 0.05). IMB skills model based nursing can improve surgical stress levels, degrees of pain, emotional state, quality of life, and nursing satisfaction of patients with gallstones and reduce the incidence of complications.

Resilience after severe critical illness: a prospective, multicentre, observational study (RESIREA)

BackgroundCritical-illness survivors may experience post-traumatic stress disorder (PTSD) and quality-of-life impairments. Resilience may protect against psychological trauma but has not been adequately studied after critical illness. We assessed resilience and its associations with PTSD and quality of life, and also identified factors associated with greater resilience.MethodsThis prospective, multicentre, study in patients recruited at 41 French ICUs was done in parallel with the NUTRIREA-3 trial in patients given mechanical ventilation and vasoactive amines for shock. Three months to one year after intensive-care-unit admission, survivors completed the Connor-Davidson Resilience Scale (CD-RISC-25), Impact of Event-Revised scale for PTSD symptoms (IES-R), SF-36 quality-of-life scale, Multidimensional Scale of Perceived Social Support (MSPSS), and Brief Illness Perception Questionnaire (B-IPQ).ResultsOf the 382 included patients, 203 (53.1%) had normal or high resilience (CD-RISC-25 ≥ 68). Of these resilient patients, 26 (12.8%) had moderate to severe PTSD symptoms (IES-R ≥ 24) vs. 45 (25.4%) patients with low resilience (p = 0.002). Resilient patients had higher SF-36 scores. Factors independently associated with higher CD-RISC-25 scores were higher MSPSS score indicating stronger social support (OR, 1.027; 95%CI 1.008–1.047; p = 0.005) and lower B-IPQ scores indicating a more threatening perception of the illness (OR, 0.973; 95%CI 0.950–0.996; p = 0.02).ConclusionsResilient patients had a lower prevalence of PTSD symptoms and higher quality of life scores, compared to patients with low resilience. Higher scores for social support and illness perception were independently associated with greater resilience. Thus, our findings suggest that interventions to strengthen social support and improve illness perception may help to improve resilience. Such interventions should be evaluated in trials with PTSD mitigation and quality-of-life improvement as the target outcomes.

NURSING STUDENTS’ POST COVID-19 PANDEMIC QUALITY OF LIFE BASED ON DEMOGRAPHIC CHARACTERISTIC

Introduction: Post Covid-19 pandemic, there was a change in nursing student habits that needed adaptability and it is important to pay attention to their quality of life. The aim of this research is to describe the Quality of Life of Post-Covid-19 Nursing Students Based on Individual Demographic Characteristics. Method: A quantitative descriptive design with a proportional stratified sampling technique to 276 of 892 nursing students was conducted in April 2023. Data were collected using the WHOQOL-BREF questionnaire to measure quality of life. This study used descriptive analysis for numerical data displayed in cross tables. Results: it was found that the quality of life of respondents tended to be good in the physical (68.25+11.27), psychological (59.78+13.62), social (68.18+15.78), and environmental (66.42+12.68) Based on the total of quality of life domains, male respondents had a higher average score than female respondents. Based on education level, it was found that respondents who were in professional programs had a higher quality of life score than those in Undergraduate Nursing Study Programs, while for history of exposure, it was found that in total, people who had been exposed had a higher quality of life than those who had not been exposed to COVID-19. Conclusions: The quality of life for nursing students after the Covid-19 pandemic has tended to be the highest level of well-being. It is necessary to identify students’ barriers in maintaining and improving their quality of life, especially in the psychological domain identified as the lowest domain.

Vision-Related Quality of Life Among Diabetic Retinopathy Patients in a Hospital-Based Population in the Sultanate of Oman.

The global prevalence of diabetic retinopathy (DR) among individuals with diabetes is 22.27%. This highlights the likelihood of developing burden of retinopathy within the at risk population and can have a detrimental impact on an individual's quality of life (QoL). The aim of this study is to assess the vision-related QoL in individuals with (DR) in a hospital-based population in the Al-Buraimi governorate, Sultanate of Oman. The study was conducted in the Ophthalmology Outpatient Department of Al Buraimi Hospital and Polyclinic. This study enrolled 218 patients (114 males, 104 females) diagnosed with DR. The NEI-VFQ-25 questionnaire was adopted in this study. The patients were classified into different groups according to their type of diabetes and other relevant demographic information. A total of 218 patients responded to the NEI-VFQ-25 questionnaire. The mean age of the participants was 57.49 ± 12.3 years, 52.3% were male, and 47.7% were female. The overall QoL score was 41.53± 20.8. Patients aged more than 75 years had the lowest QoL scores compared with the other age groups (p = 0.02). The results showed that the duration of diabetes had no significant impact on the overall QoL scores (p = 0.06). A higher QoL score was observed among patients with type II diabetes mellitus (DM) than with type I diabetes mellitus (p = 0.01). Patients diagnosed with proliferative DR (PDR) had a significantly lower QoL score than those diagnosed at other stages (p < 0.001). The QoL of the population with DR is negatively affected by various factors, including demographics, disease severity, and in patients with DM type II. It is important to consider these factors to enhance QoL in patients with DR. Regular evaluation of an individual's QoL is beneficial for both physicians and healthcare teams.

The quality of life impacting factors in malnourished patients with gastric cancer.

Malnutrition is prevalent among individuals with gastric cancer and notably decreases their quality of life (QOL). However, the factors impacting QOL are yet to be clearly defined. This study aimed to identify essential factors impacting QOL in malnourished patients suffering from gastric cancer. By using the Patient-Generated Subjective Global Assessment (PG-SGA) to assess the nutritional status (≥4 defined malnutrition) of hospitalized cancer patients, 4,586 gastric cancer patients were ultimately defined as malnourished. Spearman method was used to calculate the relationship between clinical features and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Then, univariate and multivariate logistic regression were used to observe which factors affected QOL, and subgroup analysis was performed in young and old population respectively. In addition, we used univariate and multivariate logistic regression to explore whether and how self-reported frequent symptoms in the last 2 weeks of the PG-SGA score affected QOL. In multivariate logistic regression analysis of clinical features of patients with malnourished gastric cancer, women, stage II, stage IV, WL had an independent correlation with a low global QOL scores. However, BMI, secondary education, higher education, surgery, chemotherapy, HGS had an independent correlation with a high global QOL scores. In multivariate logistic regression analysis of symptoms in self-reported PG-SGA scores in patients with malnourished gastric cancer, having no problem eating had an independent correlation with a high global QOL scores. However, they have no appetite, nausea, vomiting, constipation and pain had an independent correlation with a lower global QOL scores. The p values of the above statistical results are both < 0.05. This study demonstrates that QOL in malnourished patients with gastric cancer is determined by female sex, stage II, stage IV, BMI, secondary and higher education or above, surgery, chemotherapy, WL, and HGS. Patients' self-reported symptoms of nearly 2 weeks, obtained by using PG-SGA, are also further predictive of malnourished gastric cancer patients. Detecting preliminary indicators of low QOL could aid in identifying patients who might benefit from an early referral to palliative care and assisted nursing.

Profile of Anemia and the Relationship between Hemoglobin Levels and Quality of Life in End-Stage Chronic Kidney Disease Patients undergoing Chronic Hemodialysis at Hasan Sadikin Hospital 2021-2022

Background: Anemia is a common complication of Chronic Kidney Disease (CKD). The severity of anemia has implications for patients' quality of life. Objective: This study aims to determine the profile of Anemia and the relationship between Hemoglobin (Hb) levels and the quality of life of end-stage CKD patients undergoing chronic Hemodialysis. Methods: This study is analytical observational research with a cross-sectional design approach to explore the correlation between Hb levels and the quality of life of routine Hemodialysis patients at Hasan Sadikin Hospital, Bandung, throughout 2021-2022. Hb levels were continuous data. The quality of life of CKD patients was measured using the Indonesian version of the KDQOL questionnaire based on eight components. The obtained data were statistically analyzed using Spearman's Rank correlation. Results: This study had 150 subjects, 75 male (50.0%) and an average age of 45. The most common etiology of CKD was hypertensive nephrosclerosis (52.7%). The average Hb level was 9 g/dL. The highest quality of life score was 68, and the lowest was 41.28, with a median of 50.99. The correlation analysis results showed an r of -0.157 and p of 0.057, indicating a very weak negative correlation that is not statistically significant. Conclusion: The study's conclusion indicates no relationship between Hb levels and the quality of life of end-stage CKD patients undergoing chronic Hemodialysis.

Analysis of the Quality of Life of Patients with Morbid Obesity after Mini-Gastric Bypass

Background. The problem of obesity is becoming more and more urgent every year. Because of this, bariatric surgery is becoming increasingly popular. Objective: to assess the quality of life of obese patients after mini-gastric surgery with a biliopancreatic loop length of 150 and 180 cm. Materials and methods. Patients after mini-gastric surgery were divided into two groups depending on the length of the biliopancreatic loop. Bariatric surgery was assessed according to BAROS. Results. For the first component of BAROS, the average score in group I was 2.15 and 2.13 in group II of patients. The average score for the 2nd component of BAROS was 2.16 points in group I and 2.05 in group II of patients. The average score for the third component in group I was 2.42 versus 2.02 points in group II of patients. Conclusions. Thus, when comparing the results for the three components of the BAROS bariatric analysis reporting and evaluation system, a higher quality of life score was obtained in the group of patients who underwent mini-gastric bypass with a biliopancreatic loop length of 150 cm.

System of psychotherapy for patients with schizotypal disorder

Background. A review of the specialized literature gives an idea of the dissociation between the significant prevalence of polymorphic forms of schizotypal disorder and the lack of scientific development of psychotherapy methods for these conditions. Purpose. To develop and test the effectiveness of the system of psychotherapy of affective disorders in patients with schizotypal disorder. Materials and Methods. According to the results of preliminary clinical anamnestic, clinical, psychopathological and psychodiagnostic studies of a contingent of 100 patients with schizotypal disorder with affective disorders of various spectrums, a system of psychotherapy for the phenomena under study was developed. To evaluate the effectiveness of the developed therapeutic measures, we used SF-36 questionnaire for determining quality of life indicators. Results. The developed system of psychotherapy is implemented in two consecutive stages: the first one is aimed at affective manifestations directly, and the second one is aimed at the second stage is aimed at developing patients’ skills of perception of subjective signs of deterioration of the underlying disease. According to the results of the analysis, it was found that patients who received psychotherapeutic treatment within the developed system had significantly (p≤0.001) higher quality of life scores 3 months after the treatment treatment compared to patients who did not receive such support: the total score was 63.83±0.35 and 60.98±0.39 points, respectively. Significant differences were found between the study groups in such components of quality of life as «Life activity», «Social activity», «Social functioning» and «Mental health». Conclusions. A two-stage system of psychotherapy of affective disorders has been developed in patients with schizotypal disorder, based on the principles of personalized medicine, the first stage of which is aimed at the direct reduction of affective disorders, the second – on the acquisition of new skills of self-analysis and detection of indirect signs of deterioration of their condition, which, in combination with adequate psychopharmacologic support allowed to improve their quality of life.