Supply chain characteristics are an important driving force for innovation at the focal firm. Previous research has separately examined the impact of structural, relational, and capability dimensions of the supply chain on firm innovation. Relying on the structure-relationship-capability framework, this study explores the configurational impact of geographical distance, business concentration, and partner innovation of both the supplier-base and the customer-base on firm innovation. Necessary causality analysis (NCA) and fuzzy-set qualitative comparative analysis (fsQCA) are employed. Based on a dataset of 123 Chinese listed firms in high-tech manufacturing sectors, we provide novel insights on the antecedent configurations of the partner characteristics in both ends of supply chains for facilitating firm innovation. Our findings indicate that there are no necessary conditions for high firm innovation performance. We identify three distinct paths - namely, innovation-driven, customer-dominated, and relationship-driven configurations - that consistently lead to high firm innovation performance. From a configurational perspective, this research contributes to the innovation and supply chain literature and provides practical implications for managers to facilitate firm innovation.