High Level Research Articles

The DEP1 Mutation Improves Stem Lodging Resistance and Biomass Saccharification by Affecting Cell Wall Biosynthesis in Rice.

Plant cell walls have evolved precise plasticity in response to environmental stimuli. The plant heterotrimeric G protein complexes could sense and transmit extracellular signals to intracellular signaling systems, and activate a series of downstream responses. dep1 (Dense and Erect Panicles 1), the gain-of-function mutation of DEP1 encoding a G protein γ subunit, confers rice multiple improved agronomic traits. However, the effects of DEP1 on cell wall biosynthesis and wall-related agronomic traits remain largely unknown. In this study, we showed that the DEP1 mutation affects cell wall biosynthesis, leading to improved lodging resistance and biomass saccharification. The DEP1 is ubiquitously expressed with a relatively higher expression level in tissues rich in cell walls. The CRISPR/Cas9 editing mutants of DEP1 (dep1-cs) displayed a significant enhancement in stem mechanical properties relative to the wild-type, leading to a substantial improvement in lodging resistance. Cell wall analyses showed that the DEP1 mutation increased the contents of cellulose, hemicelluloses, and pectin, and reduced lignin content and cellulose crystallinity (CrI). Additionally, the dep1-cs seedlings exhibited higher sensitivity to cellulose biosynthesis inhibitors, 2,6-Dichlorobenzonitrile (DCB) and isoxaben, compared with the wild-type, confirming the role of DEP1 in cellulose deposition. Moreover, the DEP1 mutation-mediated alterations of cell walls lead to increased enzymatic saccharification of biomass after the alkali pretreatment. Furthermore, the comparative transcriptome analysis revealed that the DEP1 mutation substantially altered expression of genes involved in carbohydrate metabolism, and cell wall biosynthesis. Our findings revealed the roles of DEP1 in cell wall biosynthesis, lodging resistance, and biomass saccharification in rice and suggested genetic modification of DEP1 as a potential strategy to develop energy rice varieties with high lodging resistance.

Flipped classroom approach for trauma education: Attitudes of participants towards pre-course assignments before the advanced trauma life supports (ATLS) instructor course

A flipped classroom approach in principle, denotes pre-course engagement for an upcoming educational course. Although never used in trauma education, other educational literature is resplendent with the beneficial effects of pre-course engagement on the learning outcomes of the course itself. In this article we share the attitudes and perspectives of prospective Advanced Trauma Life Supports Instructors towards pre-course assignments to see whether this works in the field of trauma education.After an online pre-course session, we administered a validated questionnaire to 100 participants. The questionnaire had 4 categories - the first dealing with participants’ characteristics and the rest with their attitude and perspectives towards the pre-course sessions. The last category included three open ended questions for qualitative analysis to explain the attitudes of the participants.The participants showed a significantly positive attitude (p<0.029) towards this flipped classroom approach. The reasons cited were “effective sensitization”, “adequate feedback”, “peer learning” “user friendly platform” “enjoyable” and “relevance”. A significantly higher level of agreement with the questionnaire statements was seen amongst the private sector doctors as compared to those working in public sector medical colleges (p = 0.004). Same was observed amongst clinical specialists as compared to pre or para clinical specialists (p = 0.001). The Questionnaire had a Cronbach’s alpha of 0.86.The study concludes that a flipped classroom approach can work well in trauma education. A tailored approach, depending upon participant characteristics, may be needed to enhance the relevance of a flipped classroom approach.

Necessity of assessment and how it affects students' psyche and desire to learn: innovative digital technologies for assessment of art and music teaching in China

ABSTRACT This paper studies the use of innovative digital technologies to assess art and music creative works in China. The authors of the paper conducted an experimental study of the influence of various types of assessment, such as formative and summative, on the academic motivation and mental health of artists and musicians. The study involved second-year students from Xihua University (N = 548). The researchers used the Academic Motivation Scale (AMS) and the Depression, Anxiety and Stress Scale (DASS) as psychometric tools of the standardized methods. Summarizing the results obtained, they can conclude that summative assessment stimulates external motivation, while formative assessment contributes to the development of internal motivation of students. These results allow teachers to offer different types of assessment to strengthen a certain type of students’ motivation. The researchers also found that summative assessment could result in a higher level of amotivation. However, they did not confirm the assumption about the negative impact of summative assessment on the mental state of students.

Predicting the association of different levels of physical activity on postoperative pulmonary complications using the international physical activity questionnaire in patients undergoing thoracoscopic lung surgery under general anaesthesia: protocol for a prospective cohort study

IntroductionPostoperative pulmonary complications (PPCs) occur frequently in patients undergoing lung surgery under general anaesthesia and are strongly associated with longer postoperative hospital stays and increased mortality. The existing literature has...

The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective observational cohort study.

A significant number of patients with axial spondyloarthritis (axSpA) do not respond to biological therapy. Therefore, we decided to investigate the specificity of this group of patients and, in particular, whether haptoglobin (Hp), its polymorphism and zonulin, in addition to other clinical features, are predictors of poor response to biological treatment. 48 patients with axSpA who were unsuccessfully treated with standard drugs were converted to biological treatment, and from this time on, a 12-week follow-up was started to assess the failure of biological treatment (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) decrease < 2 points). Predictors of treatment failure were identified using logistic regression analysis. 21% of subjects had biological treatment failure. Patients who had a higher zonulin level, a history of frequent infections, were older, had inflammatory bowel disease (IBD), had a lower Hp level at the time of inclusion in biological therapy showed an increased risk of treatment failure. The results of the study support the hypothesis that the effectiveness of biological treatment of axSpA is limited by changed microbiota and intestinal epithelial barrier dysfunction, as an increased risk of biological treatment failure was observed in patients who were older, had higher zonulinlevel, IBD and repeated courses of antibiotics due to frequent infections. Therefore, starting biological treatment should be followed by reducing intestinal permeability and regulating the disturbed gut microbiome.

Association of serum total IgE and allergen-specific IgE with insulin resistance in adolescents: an analysis of the NHANES database

BackgroundRecent studies have found that total immunoglobulin E (IgE) and allergen-specific IgE were associated with some metabolic diseases. However, the role of IgE in metabolism among adolescents is still unclear. Herein, this study aims to investigate the associations of serum total IgE and allergen-specific IgE with insulin resistance (IR) in adolescents, in order to provide some reference for the prevention and treatment of metabolic diseases in a young age.MethodsData of 870 adolescents were extracted from the National Health and Nutrition Examination Survey (NHANES) database in 2005–2006 in this cross-sectional study. Weighted univariate and multivariate logistic regression analyses were utilized to screen covariates and explore the relationships of serum total IgE and allergen-specific IgE with IR. The evaluation indexes were odds ratios (ORs) and 95% confidence intervals (CIs). In addition, these relationships were also assessed in subgroups of allergy history, asthma history, and number of allergens.ResultsAmong eligible adolescents, 168 had IR. No significant association between serum total IgE level and IR was found. However, adolescents with higher level of allergen-specific IgE to rye grass [OR = 0.47, 95%CI: (0.25–0.91)], white oak [OR = 0.57, 95%CI: (0.37–0.88)], or peanut [OR = 0.38, 95%CI: (0.15–0.97)] seemed to have lower odds of IR, whereas those had higher level of shrimp-specific IgE [OR = 2.65, 95%CI: (1.21–5.84)] have increased odds of IR. In addition, these associations between allergen-specific IgE and IR were also discovered in adolescents who had allergy history or asthma history, or had different numbers of allergens.ConclusionPaying attention to different allergens in adolescents may be important in the early identification of IR among this high-risk population. The study results relatively provided some reference for further exploration on IR prevention.

Climate change disclosure performance and audit fees: evidence from Australia

Purpose This study aims to examine the relationship between climate change disclosure performance (CCDP) and audit pricing. The moderating effect of corporate governance characteristics on that relationship is also investigated. Design/methodology/approach Using a sample of top 300 Australian Securities Exchange listed non-financial firms over the period 2008–2019, this study investigates the association between CCDP and audit fees. The findings are robust to a difference-in-difference test thereby alleviating potential endogeneity concerns. Findings CCDP is found to be significantly positively related to external auditor fees. Research limitations/implications The findings show some important implications for firm management, regulators, investors and auditors. This study presents empirical evidence that climate change, as a factor of external risk, influences audit fees. Practical implications Firms with governance structures characterized by larger more independent boards, larger audit committees and audit committees with a higher level of independence significantly moderate the relationship between CCDP and audit fees. Social implications Investors’ demand for firm transparency and disclosure of information regarding the risks of climate change, effects and opportunities has increased significantly over the past decade, as these factors could have a significant effect on valuation and investment decisions. Originality/value Importantly, stakeholders need to be aware of the costs of climate change, the quantification of climate change impacts and how firms address climate change in their business risk management processes. This study quantifies the impact of CCDP on auditor risk assessments via audit fees.

Cumulative costs of severe traffic injuries in Finland: a 2-year retrospective observational study of 252 patients

Road traffic injuries cause considerable financial strain on health care systems worldwide. We retrospectively analyzed injury-related costs of 252 severely injured (New Injury Severity Score, NISS ≥ 16) patients treated at Tampere University Hospital (TAUH) between 2013 and 2017, with 2-year follow-up. The costs were divided into direct treatment, indirect costs, and other costs. We analyzed various injury- and patient-related factors with costs. The total costs during the 2-year study period were 20 million euros. Median cost was 41,202 euros (Q1 23,409 euros, Q3 97,726 euros), ranging from 2,753 euros to 549,787 euros. The majority of costs (69.1%) were direct treatment costs, followed by indirect costs (28.4%). Other costs were small (5.4%). Treatment costs increased with the severity of the injury or when the injury affected the lower extremities or the face. Indirect costs were higher in working age patients and in patients with a higher level of education. The relative proportions of direct and indirect costs were constant regardless of the amount of the total costs. The largest share of costs was caused by a relatively small proportion of high-cost patients during the 1st year after injury. Combined, this makes planning of resource use challenging and calls for further studies to further identify factors for highest costs.

AZ31-calcium-deficient hydroxyapatite (CDHA) composites produced by friction stir processing: controlling the degradation by enhancing the biomineralisation

ABSTRACT In the present work, calcium deficient hydroxyapatite (CDHA) was dispersed into the surface of AZ31 Mg alloy within the solid state by friction stir processing and the role of the refined microstructure and the presence of nano-CDHA on biomineralization and corrosion performance was investigated. Fine grains (1.6 ± 2.1 µm) have been produced in AZ31-CDHA composite compared with base alloy (41 ± 6.1 µm) and nano-CDHA was observed as reinforced into AZ31 matrix. X-ray diffraction analysis confirms the texture change due to FSP in the composite. Wettability studies carried out by measuring contact angles on the surface of the composites indicated increased surface energy (37.27 ± 5.1 mJ/m2) compared with the base alloy (20.55 ± 3.4 mJ/m2) . From the potentiodynamic polarization studies, lower corrosion current density (1.69 ± 1.13 × 10-5 A/cm2) was observed for the composite. From the immersion studies in simulated body fluids, higher level of biomineralization on the composite helped to decrease the degradation rate as reflected from the lower weight loss (7.5 ± 1.1 %) compared with the base alloy (12.1 ± 1.3 %). The results demonstrate the promising role of enhanced biomineralization on controlling the degradation of AZ31-CDHA composite..

How and when illegitimate tasks lead to cyberloafing: The role of meaningful work and appreciative leadership

This study examined how and when illegitimate tasks are related to employee cyberloafing with meaningful work and appreciative leadership. Participants were 289 employees of a Chinese energy firm (female = 59.5%; bachelor’s degree = 75.8%; mean age = 30.86 years, SD = 6.99 years). Employees completed the following surveys: Bern Illegitimate Task Scale, The Work and Meaning Inventory, Personal Recognition Scale, and the Cyberloafing scale. Following a moderated mediating model, results revealed that a higher level of illegitimate tasks were associated with more cyberloafing, but that meaningful work mediated the relationship and led to less cyberloafing. Appreciative leadership served as a moderator of the association between illegitimate tasks and meaningful work, which suggests that employees with a low level of appreciation from their supervisors perceive less meaning in their work when faced with illegitimate tasks, and so tend to engage in more non-workrelated cyber activities. The results of this study contribute to the evidence on work productivity strategies for reducing workplace illegitimate tasks and cyberloafing, offering valuable insights that can guide managers in mitigating employee cyberloafing behaviour.

Methods and associations of suicidality in Kenyan high school students: clinical and public health implications.

Most evidence on suicidal thoughts, plans and attempts comes from Western countries; prevalence rates may differ in other parts of the world. This study determined the prevalence of suicidal thoughts, plans and attempts in high school students in three different regional settings in Kenya. This was a cross-sectional study of 2652 high school students. We asked structured questions to determine the prevalence of various types of suicidality, the methods planned or effected, and participants' gender, age and form (grade level). We provided descriptive statistics, testing significant differences by chi-squared and Fisher's exact tests, and used logistic regression to identify relationships among different variables and their associations with suicidality. The prevalence rates of suicidal thoughts, plans and attempts were 26.8, 14.9 and 15.7%, respectively. These rates are higher than those reported for Western countries. Some 6.7% of suicide attempts were not associated with plans. The most common method used in suicide attempts was drinking chemicals/poison (18.8%). Rates of suicidal thoughts and plans were higher for older students and students in urban rather than rural locations, and attempts were associated with female gender and higher grade level - especially the final year of high school, when exam performance affects future education and career prospects. Suicidal thoughts, plans and attempts are prevalent in Kenyan high school students. There is a need for future studies to determine the different starting points to suicidal attempts, particularly for the significant number whose attempts are not preceded by thoughts and plans.

Out Of Pocket Expenditure Of End Stage Renal Disease Patients For Maintenance Haemodialysis.

Background: End stage renal disease (ESRD) is a major and growing public health problem in Bangladesh. It is linked to higher hospitalization rates, lost productivity, illness, and early death, and it is a major cost on people, health care systems, and societies. Haemodialysis as a life saving measure can save patients but out-of-pocket expenditure of Haemodialysis in Bangladesh is high in comparison to their monthly family income. Therefore, it places a significant financial strain on the families of the disease victims. The aim of this study was to find out the out-of-pocket expenditure of ESRD patients for maintenance haemodialysis. Methods: This descriptive cross sectional study was carried out among 160 ESRD patients getting haemodialysis at Dialysis centre of a selected tertiary government hospital in Dhaka during the period of January to December 2022. Simple random sampling technique was followed. Data were collected by face to face interview with a semi-structured questionnaire and by check list reviewing medical documents. Results: The mean (±SD) age of the respondents was 49.28 ±12.706 years. Majority (60.6%) were male and 39.4% were female. Majority (29.4%) had secondary followed by 21.9% who had higher secondary level of education. About three fourths (71.9%) were from urban, 18.8% from rural, 8.1% from semi-urban areas and 1.3% were slum dwellers. The median of monthly family income was Tk. 20000 (interquartile range 15750). The median (IQR) total direct cost was Tk. 15983 (7203). The mean (±SD) total indirect cost was Tk. 5431.25±1128.17. The mean (±SD) total haemodialysis cost was Tk. 24205.59 ±17164.580. Conclusion: Out-of-pocket expenditure of Haemodialysis in Bangladesh is high in comparison to monthly family income and it poses huge financial burden to the families of the victims of end stage renal disease. The study recommended cost effective measures like subsidized or free of cost treatment of ESRD and free of cost haemodialysis of patients to reduce the financial burden of the families. Bangladesh Armed Forces Med J Vol 56 No (1) June 2023, pp 28-34

Electroacoustic evaluation of the bone conduction transducer B250 for vestibular and hearing diagnostics in comparison with Radioear B71 and B81

Objective The objective is to evaluate the electroacoustic performance of the B250 transducer and to compare it with the two most widely used audiometric transducers B71 and B81. Design The electroacoustic performance was evaluated in terms of sensitivity level, distortion, maximum hearing level and electrical impedance. Study sample Six B250 prototype transducers were evaluated and compared with published data of B71 and B81 together with complementary measurements of maximum hearing level at 125 Hz and phase of electrical impedance. Differences in reference equivalent threshold vibratory force levels were estimated by comparing hearing threshold measurements of 60 healthy ears using B81 and B250. Results B250 has approximately 27 dB higher sensitivity levels than both B71 and B81 at 250 Hz and can generate higher maximum hearing level at low frequencies: 11.8 to 35.8 dB (125–1000 Hz) higher than B71, and 1.4 to 18.6 dB (125–750 Hz) higher than B81. The maximum average difference in reference threshold force levels was 13.5 ± 8.7 dB higher for B250 at 250 Hz compared to B81. Conclusions B250 can produce higher output force with less distortion than B71 and B81, especially at 125 and 250 Hz, which could possibly improve low frequency investigations of the audio-vestibular system.

“Swipe &amp; slice”: decoding digital struggles with non-suicidal self-injuries among youngsters

IntroductionNonsuicidal-self-injury (NSSI)-related content recently emerged on social networking sites (SNS), despite its relationship with NSSI conducts is still unclear.MethodsHence, the current population-based cross-sectional study investigated the interplay between SNS use, NSSI content engagement, risky social media challenges (RSMCs), in a sample of 404 young adults (aged 18–24), focusing on the influence of problematic social media use (PSMU) and fear of missing out (FoMO).ResultsAround 51.5% of the samplewas engaged inNSSI-related contents on SNS, being mostly females (p&amp;lt;0.001), younger (p=0.005), transgender people and nonbinary people (p=0.030) and those who displayed higher PSMU (p&amp;lt;0.001) or FoMO (p=0.031). Around 66.2% of the sample currently practice NSSIs, predominantly among females (p&amp;lt;0.001), those using BeReal (p=0.012), actively looking for NSSIrelated contents on SNS (p&amp;lt;0.001) to be part of a group (p=0.0025) or learn how to practice NSSI (p=0.025). PSMU (p&amp;lt;0.001) and FoMO (p&amp;lt;0.001) emerged as significant predictors of NSSI content engagement, particularly among active seekers. NSSI conducts were significantly predicted by FoMO (p&amp;lt;0.001) and Snapchat (p=0.044), while negatively predicted by male sex (p&amp;lt;0.001), higher educational level (p=0.019) and age at which NSSI-related contents were firstly looked for (p=0.028).DiscussionThese findings underline the need to implement preventivepolicies and targeted interventions to monitor NSSI-related contents on SNS, the impact of PSMU and FoMO on NSSI, particularly among youngsters.

Policing neighborhood boundaries and the racialized social control of spaces

Abstract Prior scholarship has established that controlling space is central to policing, while highlighting various ways in which this form of social control can be racialized. Extending this work, we advance a theory on the racialized control of space that predicts a higher level of police stops and lower standards of suspicion along neighborhood racial boundaries, the areas where racial composition changes between adjacent neighborhoods. Our theoretical argument sheds light on the selective enforcement of law and order in these transitional spaces, which is a form of racialized spatial social control. Integrating data from New York City’s Stop, Question, and Frisk program from 2008 to 2012 with extensive neighborhood measures, our analyses reveal that White neighborhoods along boundaries experienced substantially elevated levels of police stops even after conditioning on a wide array of potential confounders. This relationship is partially mediated by elevated crime along neighborhood racial boundaries. Still, a sizable direct effect persists, indicative of the racialized social control of spaces. Further, the police tended to require less suspicion before deciding to conduct stops in White neighborhoods along racial boundaries, but only for Black and Hispanic suspects. Implications for the study of race and policing, law and society, and urban and racial inequality are discussed.

The Valorization of Spanish Minority Grapevine Varieties—The Volatile Profile of Their Wines as a Characterization Feature

Despite the large number of existing varieties of Vitis vinifera L., only few occupy a large niche in today’s highly globalized wine market. The increasing consumer demand for diversified products, as well as the changing climatic conditions, make establishing a process of varietal diversification essential to achieve both challenges. It is for this reason that the study of minority varieties, which have a higher level of adaptation to each area of origin, is of particular interest. With the main objective of achieving an in-depth knowledge of minority varieties in Spain, the national research project ‘Valorization of Minority Grapevine Varieties for their Potential for Wine Diversification and Resilience to Climate Change’ (MINORVIN), has been proposed. Within this extensive project, the present study describes the aroma profiles of 60 single-variety wines, corresponding with 44 different varieties, with 12 of these varieties being studied at the same time in several Spanish regions. Volatile compounds were determined through three consecutive vintages using gas chromatography-mass spectrometry (GC-MS) and gas chromatography–flame ionization detector (GC-FID). Compounds were grouped into major compounds, including alcohols, C6 compounds, esters, acetates, acids, carbonyl compounds, and other type of compounds, and minor compounds, including lactones, terpenes, and C13-norisoprenoids, according to their concentration in the wines being analyzed. Among this last group of compounds, lactones were quantitatively the most abundant, followed by terpenes. This study reflects that minority variety wines show distinctive aromatic profiles, supporting the importance of valuing and promoting the autochthonous minority grapevine varieties for the Spanish winemaking industry.

The effect of justice sensitivity on malevolent creativity: the mediating role of anger and the moderating role of emotion regulation strategies

Backgroundthe AMORAL model emphasizes the close connection of individuals’ belief system and malevolent creativity. Belief in a just world theory (BJW) states that people have a basic need to believe that the world they live in is just, and everyone gets what they deserve. Therefore, justice matters to all people. Justice sensitivity, as one of individual trait, has been found associated with negative goals. However, relevant studies have not tested whether justice sensitivity can affect malevolent creativity and its psychological mechanisms. Additionally, researchers have found that both anger and emotion regulation linked with justice sensitivity and malevolent creativity, but their contribution to the relationship between justice sensitivity and malevolent creativity remained unclear. The current study aims to explore the influence of justice sensitivity on malevolent creativity, the mediating effect of trait anger/state anger on the relationship between justice sensitivity and malevolent creativity, and the moderating effect of emotion regulation on this mediating effect.MethodsA moderated mediating model was constructed to test the relationship between justice sensitivity and malevolent creativity. A sample of 395 Chinese college students were enrolled to complete the questionnaire survey.ResultsJustice sensitivity positively correlated with malevolent creativity, both trait anger and state anger partly mediated the connection between justice sensitivity and malevolent creativity. Moreover, emotion regulation moderated the indirect effect of the mediation model. The indirect effect of justice sensitivity on malevolent creativity through trait anger/state anger increased as the level of emotion regulation increased. The results indicated that justice sensitivity can affect malevolent creativity directly and indirectly through the anger. The level of emotion regulation differentiated the indirect paths of justice sensitivity on malevolent creativity.ConclusionsJustice sensitivity and malevolent creativity was mediated by trait anger/state anger. The higher sensitivity to justice, the higher level of trait anger/state anger, which in turn boosted the tendency of malevolent creativity. This indirect connection was moderated by emotion regulation, individuals with high emotion regulation are better able to buffer anger from justice sensitivity.

The use of artificial neural networks and decision trees: Implications for health-care research

Abstract The use of decision trees and artificial neural networks (ANNs) in health-care research is widespread, as they enable health-care providers with the tools they need to make better medical decisions with their patients. ANNs specifically are extremely helpful in predictive research as they can provide investigators with knowledge about future trends and patterns. However, a major downside to ANNs is their lack of interpretability. Understandability of the model is important as it ensures the outcomes are true to the dataset’s original labels and are not impacted by algorithmic bias. In comparison, decision trees map out their entire process before providing the results, which leads to a higher level of trust in the model and the conclusions it supplies the investigators with. This is essential as many historical datasets lack equal and fair representation of all races and sexes, which might directly correlate to a lesser treatment given to females and individuals in minority groups. Here, we review existing work around the differences and connections between ANNs and decision trees with implications for research in health care.

A Study of Grade Eleven Student's Representations of Electricity Through Model-Based Inquiry

The COVID-19 pandemic forced schools to close and transition online. The authors are interested in whether students have a higher level of representation after learning via an online learning platform through the Model-Based Inquiry (MBI) method and how they can be supported. This study took place in a school in a western province of Thailand, with thirty-two students studying in grade eleven. The study was conducted in an online classroom, implementing an action research strategy with two action research loops. The first loop consisted of three lessons, followed by another three lessons in the second loop, all aimed at improving the students' representations. To collect data, a representation test was used after both loop one and loop two implementations. The students' representations were then interpreted and grouped into five levels. The quality of each answer was assessed using criteria which included fair, good, and very good categories. The results demonstrated that students' representations were enhanced through model-based inquiry. There was a noticeable improvement in the students' representations from loop 1 to loop 2 of the action research at all three levels, consisting of the macroscopic level, microscopic level, and symbolic level.

Predictors of family-focused practices among mental health workers in Quebec

ContextEngaging family members in the ongoing care of individuals with mental illness is a practice known to bolster the client’s recovery journey and enhance the overall wellbeing of both children and families involved. Despite its potential benefits, there remains a dearth of understanding surrounding the implementation of family-focused practices (FFP) by mental health professionals serving adults, as well as the factors that could either promote or hinder such practices. This knowledge gap is particularly pronounced within North American settings.GoalThe goal of this study was to identify potential hindering and enabling factors of FFP used in adult mental health services.MethodsA sample of 512 professionals working with adult mental health clients, from all regions of Quebec, Canada, with a variety of disciplinary backgrounds and working in different work settings, completed the Family Focused Mental Health Practice Questionnaire (FFMHPQ). Multinominal logistic regression analysis was performed to assess the impact of several factors – organizational, professional, and personal – on the degree of family-based practices of mental health workers.Results and discussionFindings of this study show that the strongest predictors for the adoption of higher FFP levels among adult mental health professionals in Quebec, are being employed on a full-time basis, perceiving a higher level of skills, knowledge, and confidence toward FFP, and having a supportive workplace environment. Results underscore the need to address both organizational and worker-related aspects to effectively promote better FFP in mental health services.