This paper reports the findings from a three-dimensional direct numerical simulation conducted to investigate the turbulent flame behaviors of premixed high-hydrogen content syngas (with 50% hydrogen on a per mole basis) and air mixtures. To accomplish this, a laminar flame front is placed in a homogeneous isotropic decaying turbulence field composed of a syngas–air mixture at an equivalence ratio of 0.7 and allowed to evolve for 1.4 eddy turnover times. Homogeneous isotropic turbulence is generated using a helical forcing function in a cubic domain with a grid size of 256 × 256 × 256. The Reynolds number based on the Taylor microscale, Reλ, is 57 for the generated turbulence field. The laminar flame front is placed at the center of the domain. The premixture enters the domain at a velocity of 8 m/s and at an initial temperature of 800 K. The pressure remains constant at 1 atm. In addition to quantifying the spatial and temporal evolution of turbulent characteristics and flame structure, the study also focuses on identifying turbulence/flame interactions, specifically, the impact of these interactions on flame thickness. Energy transfer from small to large scales, i.e., a reverse cascade is observed as a result of energy release due to chemical reactions at the small scales that is transferred to larger scales. The increase in turbulent intensities due to chemical reactions correlates with flame thickening.