High Ambient Humidity Research Articles

The Efficacy of Nutritional Strategies and Ergogenic Aids on Acute Responses and Chronic Adaptations to Exertional-Heat Exposure: A Narrative Review

Global warming is attributed to an increased frequency of high ambient temperatures and humidity, elevating the prevalence of high-temperature-related illness and death. Evidence over recent decades highlights that tailored nutritional strategies are essential to improve performance and optimise health during acute and chronic exertional-heat exposure. Therefore, the purpose of this review is to discuss the efficacy of various nutritional strategies and ergogenic aids on responses during and following acute and chronic exertional-heat exposure. An outline is provided surrounding the application of various nutritional practices (e.g., carbohydrate loading, fluid replacement strategies) and ergogenic aids (e.g., caffeine, creatine, nitrate, tyrosine) to improve physiological, cognitive, and recovery responses to acute exertional-heat exposure. Additionally, this review will evaluate if the magnitude and time course of chronic heat adaptations can be modified with tailored supplementation practices. This review highlights that there is robust evidence for the use of certain ergogenic aids and nutritional strategies to improve performance and health outcomes during exertional-heat exposure. However, equivocal findings across studies appear dependent on factors such as exercise testing modality, duration, and intensity; outcome measures in relation to the ergogenic aid’s proposed mechanism of action; and sex-specific responses. Collectively, this review provides evidence-based recommendations and highlights areas for future research that have the potential to assist with prescribing specific nutritional strategies and ergogenic aids in populations frequently exercising in the heat. Future research is required to establish dose-, sex-, and exercise-modality-specific responses to various nutritional practices and ergogenic aid use for acute and chronic exertional-heat exposure.

Sustainable commercially-scaled greenhouse building cooling solution: Integrating PCM storage, desiccant wheels, and absorption chillers powered by dual-source solar/biomass energy

This research aims to address the critical need for sustainable cooling systems in greenhouses, particularly relevant in mitigating global warming impacts and enhancing food security worldwide. The urgency becomes more pronounced in locations experiencing high ambient temperature and humidity. The study introduces an innovative cooling system integrating Phase Change Material, a desiccant wheel, and an absorption chiller, powered by solar and biomass energy. This novel system aims to efficiently regulate temperature and humidity in greenhouse environments. The performance of this system is examined in Abu Dhabi, Doha, and Riyadh during the summer months, utilizing TRNSYS software for a medium-scale greenhouse model. Additionally, a comprehensive Life Cycle Assessment is carried out to quantify the environmental impacts of the proposed system. Results indicate that in Abu Dhabi, the system yields a Coefficient of Performance (COP) of 1.108, effectively maintaining indoor climate conditions. Similarly, Doha and Riyadh exhibit COPs of 1.015 and 0.827, respectively. In terms of solar energy utilization, Abu Dhabi demonstrates a solar fraction of 40.4, corresponding to the lowest Global Warming Potential (GWP) at 0.106 kg CO2eq per 1 kW of provided cooling capacity. Conversely, Riyadh records the highest GWP at 0.149 kg CO2eq, followed by Doha at 0.118 kg CO2eq. The Energy Payback Time (EPBT) for the system in Abu Dhabi is calculated to be 3.96 years, the shortest among the examined cities. In comparison, Doha and Riyadh present longer EPBTs of 4.48 and 5.83 years, respectively. These findings suggest that the proposed system offers a viable and environmentally friendly alternative to conventional greenhouse cooling approaches.

Exacerbation of Hepatic Damage in Endothelial Aquaporin 1 Transgenic Mice after Experimental Heatstroke.

Heatstroke induces fluid loss and electrolyte abnormalities owing to high ambient temperature (AT) and relative humidity (RH). Aquaporin 1 (AQP1) is a key protein for water homeostasis; however, its role in heatstroke remains unclear. This study examines endothelial AQP1 in Tie2-Cre/LNL-AQP1 double transgenic (dTG) mice with upregulated Aqp1 in endothelial cells. For experimental heatstroke, mice were exposed to 41 °C AT and >99% RH. Blood, brain, kidney, and liver samples were collected 24 h later. Blood was analyzed for electrolytes and tissue damage markers, and organs were examined using morphological and immunohistological staining for 3-nitrotyrosine (3-NT), AQP1, and Iba-1. No difference in Aqp1 expression was observed in the whole brain; however, it was detected in dTG mice after capillary deprivation. AQP1 immunostaining revealed immunoreaction in blood vessels. After heat exposure, wild-type and dTG mice showed electrolyte abnormalities compared with non-heatstroke wild-type mice. Hepatic damage markers were significantly higher in dTG mice than in wild-type mice. Hematoxylin-eosin staining and 3-NT immunoreactivity in the liver indicated hepatic damage. The number of Iba-1-positive cells adherent to hepatic vasculature was significantly higher in dTG mice than in wild-type mice. This study is the first to suggest that endothelial AQP1 contributes to hepatic damage after heatstroke.

Effects of High Temperature and High Humidity on the Degree of Ocular Damage Caused by 60 GHz Millimeter Wave Exposure.

Millimeter waves (MMW) are pervasive in society; however, studies on the biological effects of MMW exposure are usually performed in laboratory settings not reflecting global environmental diversity. We investigated the effects of a 6-min exposure to 60 GHz MMW (wavelength, 5.0 mm) at incident power densities of 200 and 300 mW cm-2 in eyes (exposed right eyes vs. unexposed left eyes) under various ambient temperature/relative humidity environments (24 °C/50%, 45 °C/20%, and 45 °C/80%) using an in vivo rabbit model. Correlations were examined with adverse ocular events, including corneal epithelial damage (assessed using fluorescein staining), corneal opacity (evaluated by slit-lamp microscopy), and corneal thickness (measured via optical coherence tomography). Our findings indicate that higher temperatures and humidity tend to exacerbate MMW-induced ocular damage, albeit not significantly in the present study. Further research with a larger sample size is warranted. Incident power density emerged as a factor that was directly linked to the ocular damage threshold. High ambient temperature and humidity tended to exacerbate ocular damage from MMW exposure, although the effect was secondary. Ocular damage in a high-temperature (45 °C), high-humidity (80%) environment was increased to the same extent as that by incident power density increased by approximately 100 mW cm-2 in an ocular damage model in a standard environment (24 °C, 50%). In a high-humidity environment, the internal ocular tissue temperature increased at a high ambient temperature of 45 °C, suggesting that the eyeball may respond differently compared to other tissues.

Ultra-low temperature selective catalytic reduction of NOx into N2 by micron spherical CeMnOx in high-humidity atmospheres containing SO2

The solvothermal synthesis of optimized micron-sized spherical Ce1Mn7Ox-350 yields remarkable results in ultra-low temperature NH3-SCR of NOx, with over 91 % NOx conversion achieved between 59 and 255 ℃. Notably, under 5 vol% H2O and 50 ppm SO2, the Ce1Mn7Ox maintains NOx conversion >99 % at 127 ℃ for extended periods, surpassing current ultra-low temperature deNOx standards. This superior performance is attributed to the material's unique characteristics: the regular and porous surface morphology enhances exposure to active sites, particularly Mn3O4(112) facets crucial for ultra-low temperature deNOx, while the rough and loose surface and high Mn2O3(222) exposure mitigate water vapor and SO2 poisoning. Furthermore, the thermal storage effect of the Mn2O3/Mn3O4 system within Ce1Mn7Ox facilitates rapid thermal dissipation and ammonium sulfite decomposition. This process is further augmented by the pores, which aid in the confinement of deNOx reaction heat and facilitate the flushing of flowing flue gas, thereby impeding the formation of ammonium bisulfate.

Light drives nitrogen fixation in tropical montane cloud forests in Costa Rica

Tropical montane cloud forests are high altitude ecosystems characterized by very high ambient humidity, which favors organisms that depend on the environment for their water status, such as bryophytes and their nitrogen-fixing symbionts. Bryophyte-associated N2 fixation is a major source of new N in several northern environments, but their contributions to the N cycle in other ecosystems is still poorly understood. In this work, we evaluated N2 fixation rates associated with epiphytic bryophytes growing along the stems of pumpwood trees (Cecropia sp.) as well as in surrounding litter and soil from a primary and a secondary cloud forests in the Talamanca Mountain Range, Costa Rica. Nitrogen fixation was significantly higher in substrates from the secondary forest compared to those from the primary forest. Overall, N2 fixation rates associated with epiphytic bryophytes were 57 times those of litter and 270 times what was measured in soil. Further, light intensity was the major factor influencing N2 fixation rates in all substrates. Increased access to light in disturbed cloud forests may therefore favor bryophyte-associated N2 fixation, potentially contributing to the recovery of these ecosystems.

Coprecipitation Strategy for Halide-Based Solid-State Electrolytes and Atmospheric-Dependent In Situ Analysis.

In the continuous pursuit of an energy-efficient alternative to the energy-intensive mechanochemical process, we developed a coprecipitation strategy for synthesizing halide-based solid-state electrolytes that warrant both structural control and commercial scalability. In this study, we propose a new coprecipitation approach to synthesized Li3InCl6, exhibiting both structural and electrochemical performance stability, with a high ionic conductivity of 1.42 × 10-3 S cm-1, comparable to that of traditionally prepared counterparts. Through the in situ synchrotron X-ray diffraction technique, we unveil the stability mechanisms and rapid chemical reactions of Li3InCl6 under dry Ar, dry O2, and high-humidity atmosphere, which were not previously reported. Furthermore, the fast reversibility capability of moisture-exposed Li3InCl6 was tracked under vacuum, revealing the optimal recovery conditions at low temperatures (150-200 °C). This work addresses the critical challenges in structural engineering and sustainable mass production and provides insights into chemical reactions under real-world conditions.

Study on desorption characteristics of water vapor in fly ash concrete materials

In this paper, water vapor desorption tests are carried out on water-saturated concrete materials with different water-binder ratios and fly ash content. The desorption parameters are analyzed using the adsorption curve analysis method, which enables the acquisition of desorption characteristics for concrete materials. By utilizing the desorption isothermal curve, the desorption rate is calculated and further analysis is conducted on the influence of water-binder ratio and fly ash content on this rate. The results indicate that the desorption and activation energy for water vapor desorption in concrete materials is higher than the adsorption energy at the first layer, suggesting that removing water vapor from inner pore walls is more challenging than its adsorption. The amount of water vapor released from concrete materials follows a power function over time, as does the rate of desorption. Under conditions of relatively low ambient humidity, an increase in the water-binder ratio leads to a decrease in the rate of desorption. Conversely, under relatively high ambient humidity, an increase in the water-binder ratio results in an increased rate of desorption.

The Antioxidant and Anti-Inflammatory Properties of Wild Bilberry Fruit Extracts Embedded in Mesoporous Silica-Type Supports: A Stability Study.

Polyphenolic extracts from wild bilberries (Vaccinium myrtillus L.) have shown antioxidant and anti-inflammatory effects, but they are prone to degradation when exposed to environmental factors, limiting their use in biomedical applications. To overcome this issue, this study proposed the embedding of wild bilberry fruit ethanolic extracts in pristine mesoporous silica functionalized with organic groups (mercaptopropyl and propionic acid), as well as coated with fucoidan, a biopolymer. Herein, we report a stability study of free and incorporated extracts in mesoporous silica-type supports in high-humidity atmospheres at 40 °C up to 28 days, using HPLC analysis, thermal analysis, and radical scavenging activity determination. Better chemical and thermal stability over time was observed when the extracts were incorporated in mesoporous silica-type supports. After 12 months of storage, higher values of antioxidant activity were determined for the extract embedded in the supports, silica modified with mercaptopropyl groups (MCM-SH), and fucoidan-coated silica (MCM-SH-Fuc) than that of the free extract due to a synergistic activity between the support and extract. All encapsulated extracts demonstrated remarkable effects in reducing NO production in LPS-stimulated RAW 264.7 cells. The treatment with extract embedded in MCM-SH-Fuc in a dose of 10 μg/mL surpassed the effect of free extract in the same concentration. For the extract encapsulated in an MCM-SH support, a lower IC50 value (0.69 μg/mL) towards COX-2 was obtained, comparable with that of Indomethacin (0.6 μg/mL). Also, this sample showed a higher selectivity index (2.71) for COX-2 than the reference anti-inflammatory drug (0.98). The developed formulations with antioxidant and anti-inflammatory properties could be further used in nutraceuticals.

Observations and modelling of mosquito prevalence within urban areas – A case study from Uppsala, Sweden

Urban green–blue infrastructure (GBI) can provide important benefits to urban residents but may also affect mosquito abundance, with associated negative nuisance and infection transmission impacts. This study addresses important knowledge and quantification gaps for the relationships between mosquito prevalence and GBI features within cities. This is done for the city of Uppsala in Sweden as an urban case example, where mosquitos were captured and ambient air temperature and humidity were observed at seven different locations in the summer of 2022. A weighted multi-critera analysis (WMCA) model was developed based on relevant open data and open tools for resolving the mosquito (Culex pipiens) variations based on geographical variables, such as land cover/use, leaf area index, and building and green (vegetation) area fractions, within the city. The results show a clear relationship between mosquito prevalence and green-area fraction (of grass and trees), indicating that urban GBI extension can enhance mosquito prevalence, with possible associated negative impacts. This relationship is supported directly by data, showing significantly higher mosquito prevalence with higher ambient humidity, which in turn is related to larger green-area fraction. The developed WMCA model emerges as a promising tool, e.g., for urban development planning that needs to account for and seek relevant trade-off balances between positive and negative effects of urban GBI changes.

A green solvent engineering process for synthesizing perovskite films in high humidity atmospheres for efficient solar cells

High quality perovskite films processed using only green solvents in a high humidity atmosphere.

Formation of atmospheric molecular clusters containing nitric acid with ammonia, methylamine, and dimethylamine.

This study investigates the formation of atmospheric molecular clusters containing ammonia (NH3, A), methylamine (CH3NH2, MA), or dimethylamine (CH3NHCH3, DMA) with nitric acid (HNO3, NA) using quantum mechanics. The Atmospheric Cluster Dynamic Code (ACDC) was employed to simulate the total evaporation rate, formation rate, and growth pathways of three types of clusters under dry and hydrated conditions. This study evaluates the enhancing potential of A/MA/DMA for NA-based new particle formation (NPF) at parts per trillion (ppt) levels. The results indicate that A/MA/DMA can enhance NA-based NPF at high nitric acid concentrations and low temperatures in the atmosphere. The enhancing potential of MA is weaker than that of DMA but stronger than that of A. Cluster growth predominantly follows the lowest free energy pathways on the acid-base grid, with the formation of initial acid-base dimers (NA)(A), (NA)(MA), and (NA)(DMA) being crucial. Hydration influences the evaporation rate and formation rate of clusters, especially for initial clusters. When the humidity is at 100%, the formation rate for NA-A, NA-MA, and NA-DMA clusters can increase by approximately 109, 107, and 104-fold compared to the corresponding unhydrated clusters, respectively. These results highlight the significance of nitric acid nucleation in NPF events in low-temperature, high-humidity atmospheres, particularly in regions like China with significant automobile exhaust pollution.

On the Chemical Composition and Hygroscopicity of Aerosols Deposited on the Insulators of Italian Power Lines

The reliability of the national power grid is a key issue in modern society. Atmospheric aerosols are the main cause of the reduction in the performance of insulators and the increase in the possibility of flashovers, resulting in power line failures. Under high ambient humidity, the water-soluble compounds of atmospheric aerosols collected on the insulators’ surface can dissociate in ions and form a conductive layer, which may lead to flashover events. With a view to investigating the processes that drive these phenomena, the chemical composition of aerosol deposits on insulators in Italy was determined by ion chromatography analysis and thermos-optical and X-ray techniques. In addition, a synthetic aerosol with the same analyzed chemical composition was generated in a laboratory and deposited on PTFE filters and glass specimens allowing us to determine the deliquescence and crystallization relative humidity and the conductive effect in an aerosol exposure chamber. The results evidenced the presence of a hazardous inorganic ion layer, which generates a sharp phase transition of the aerosol deposit as a function of the ambient relative humidity; this layer poses a dangerous threat to the reliability of the power grid, increasing the probability of flashover events where the conductive layer facilitates the flow of electrical current across the insulator surface, potentially causing power outages or damage to the power lines.

Comparison of hermetic and conventional bags for maize seed preservation in Azad Kashmir, Pakistan

Maize (Zea mays L.) is a major cereal crop used as a staple food worldwide for decades. Farmers store their produce in porous polypropylene bags under humid conditions which negatively affects their quality. In this study, maize seeds were stored in hermetic and conventional bags with an initial seed moisture content of 13.5% (wet basis) and 96.3% germination for 8 months at four major maize growing districts (Athmuqam, Hattian Bala, Muzaffarabad and Rawlakot) of Azad Jammu and Kashmir, Pakistan. Due to high ambient relative humidity conditions (>80%), an increase in moisture was observed in seeds stored in porous conventional bags (14. 7%). This increase was because of high initial relative humidity conditions (79–85%) in conventional bags. Seed moisture content remained unchanged in hermetic bags and internal humidity was 59–60%. As a result of hermetic conditions, germination and seed integrity were maintained in hermetic bags compared to conventional woven bags. Germination drastically decreased in conventional bags and fell to 9 % (Athmuqam), 13 % (Hattian Bala), 11 % (Muzaffarabad) and 12 % (Rawlakot). Higher physical quality losses of maize in conventional bags were because of infestation activity of live insect pest populations (S. zeamais, R. dominica and T. castaneum) that initiated 21.7–23.7 % weight loss in polypropylene bags. Hermetic bags protected seeds from insect pest attack and maintained seed quality. Higher contamination of aflatoxin B1, G1, B2 and G2 (ppb) was recorded in seeds stored in conventional bags as compared to hermetic bags. Aflatoxin B1 was maximum in conventional bag at Hattian Bala (8.93 ppb) followed by Muzaffarabad (6.68 ppb), Athmuqam (5.02 ppb) and Rawlakot (0.71 ppb). In conclusion, the use of hermetic dry chain storage preserves maize seed quality and thus can have a significant impact on the livelihoods of smallholder farmers of humid areas.

On the influence of humidity on the breakdown strength of air—with a case study on the PDIV of contacting enameled wire pairs

The partial discharge inception voltage (PDIV) in contacting enameled wire pairs exhibits a marked decrease with increased air humidity. While existing literature mentions several potential mechanisms for this reduction, a comprehensive quantitative assessment of the associated effects is lacking. This research paper addresses this knowledge gap by providing a quantitative estimation of the combined impact of water on the gas’s ionization yield (effective ionization coefficient) and the modification of the gap electric field caused by water absorption into the bulk of the insulating coating and the associated microscopic and macroscopic polarization processes (dielectric permittivity). However, a comparison of the theoretical predictions with experimental data reveals that these factors alone cannot fully account for the observed reduction in PDIV. Therefore, the study explores additional mechanisms mentioned in the literature, with particular focus on the development of a semi-conductive layer on the insulation coating in humid atmospheres. The numerical simulations of the surface charge dynamics within this layer suggests that the frequency-dependent decrease in PDIV under high-humidity atmospheres can indeed be attributed to the modification of the gap electric field due to the accumulation of surface charge in the semi-conductive layer.

Impedance Measurement and Demonstrator Tests of Developed Thermally Sprayed and Sealed Coating Systems for Bearing Applications

To avoid early stage failure of rolling bearings as components of train drives of electrical engines, the bearings must be protected. As state of the art, alumina coatings are applied by atmospheric plasma spraying and subsequently an organic sealer is used to enhance the service life of these bearings under harsh conditions. This includes high applied frequencies and high ambient air humidity. For further improvement, mullite coatings and a newly developed an epoxy‐ and silicon‐based sealer applied by different sealing techniques are investigated to further enhance the electrical insulation of the bearing coatings. Impedance measurements under dry and wet conditions are conducted to analyze the capacitive behavior of the coatings. X‐ray diffraction measurements are used to correlate the influence of the present crystallographic phases of the ceramic coating on the capacitive behavior. In a following step, selected coating systems are applied onto bearings and tested in demonstrator tests. For higher currents of roughly IBearing ≥ 0.6 A, all newly developed coatings exhibit a decreased number of electrical breakdowns compared to the reference. Consequently, choosing this coating system as electrical protection coating for bearings in electrical engines can reduce the damage occurring from electrical current breakdowns.

MoO2 Pump-Enhanced Flexible TiO2 Nanojungle-Based Chemiresistors for Rapid Room-Temperature Detection of H2S at Parts-per-Billion Levels.

In this study, we developed a gas sensing platform that can sensitively and specifically detect trace H2S in a high-humidity atmosphere at RT. Upon integrating a carbon nitride (C3N4) nanofilm and molybdenum dioxide (MoO2) nanosheets onto nanojungle-like TiO2 nanotube arrays (TiNTs), the fabricated chemiresistor showed rapid response (38 s)/recovery (58 s) abilities and remarkable detection sensitivity for H2S at concentrations down to 2 ppb, with an estimated detection limit of 1.13 ppb at RT and room-environmental light (REL). Importantly, the gas sensor exhibited satisfactory H2S sensing performance even in dark conditions with a response of 1.9 at 200 ppb. In this design, apart from the architectural advantages of the nanojungle-like TiNTs for accelerating the gas flow efficiency and the abundant sensing sites provided by the C3N4 film, the MoO2 nanosheets act as the essential electron pump not only for the H2S response but also for the subsequent recovery process in air. After employing the MoO2 pump onto C3N4/TiNTs, the response time and recovery time of the system are shortened to ∼35 and ∼11%, respectively. Moreover, we demonstrated the good performance of the flexible gas sensor in detecting trace H2S in human exhaled breath with good humidity resistance. These results highlight the possibility of designing chemiresistors operating in RT and REL conditions and to use these environmentally friendly TiO2-based sensors in real applications.

An update on high temperature tantalum capacitor technology

Developments and improvements in the materials, design and manufacturing of tantalum bulk capacitors have resulted in new case sizes, improved ESR, higher operating voltages and temperatures. This work discusses the basic design and manufacture of hermetic tantalum and wet tantalum capacitors and the resulting high temperature performance offered by each technology. Specifically, hermetic sealed tantalum capacitors offer a novel set of design options for the high temperature designer. This technology, exhibits superior stability when exposed to high temperatures, high humidity, and ambient atmosphere. The device is impervious to the typical capacitance drop common to high temperature capacitor operation. Thus they enable potentially significant size reductions, lower component counts, and reliability improvements in extremely high temperature applications, such as downhole oil drilling. Both electrical and physical comparisons are made between the characteristics of bulk stacked ceramic capacitors, hermetic tantalum and wet tantalum devices across an operating range of -55°C to +230°C. Lifespan and recommended de-ratings are presented.

Enhancing Gas Turbine Power Plant Performance in Tropical Climates by Using Inlet Air Cooling with Desiccant Dehumidification and Evaporative Cooling

Abstract Gas turbine power plants play a crucial role in meeting the growing demand for electrical energy. However, their performance can be hindered by high ambient temperatures and humidity levels in tropical climates, leading to a drop in power output. This study investigates the potential benefits of using inlet air cooling with desiccant dehumidification and evaporative cooling to improve the performance of gas turbine power plants in tropical regions. The results show that this inlet air cooling method, integrating evaporative cooling, desiccant wheel, and Maisotsenko cooler, is a viable alternative for mitigating the performance decrease of gas turbines in hot tropical conditions. Furthermore, the compressor inlet temperature can be reduced on average by 11.5 °C by using turbine exhaust gases to heat the regeneration air utilized in the desiccant wheel for dehumidification. Additionally, the power requirement of the inlet air cooling system amounts to around 0.9 MW compared with an improvement of more than 2 MW in power output at peak temperature. Further research is needed to understand and quantify other benefits related to inlet air cooling, such as reducing emissions of harmful pollutants and operating at higher turbine inlet temperatures.

The burden, risk factors and unique etiologies of stroke in South-East Asia Region (SEAR).

The World Health Organization (WHO) South East Asia Region (SEAR) comprises 11 countries, which are one of the most culturally, topographically, and socially diverse areas worldwide, undergoing an epidemiological transition towards non-communicable diseases, including stroke and other cardiovascular diseases (CVDs). This region accounts for over 40% of the global stroke mortality. Few well-designed population-based epidemiological studies on stroke are available from SEAR countries, with considerable variations among them. Ischemic stroke, a common stroke subtype, has higher frequencies of intracerebral hemorrhage in many countries. Along with an aging population, the increased prevalence of risk factors such as hypertension, diabetes mellitus, tobacco and alcohol consumption, lack of physical activity, high ambient pollution, heat, and humidity contribute to the high burden of stroke in this region. SEAR's many unique and uncommon stroke etiologies include cerebral venous thrombosis, tuberculosis, dengue, scrub typhus, falciparum malaria, snake bite, scorpion sting, etc. Current data on stroke burden and risk factors is lacking, compelling an urgent need for high-quality hospital-level and population-level data in all SEAR countries. Strategies towards a consolidated approach for implementing improved stroke prevention measures, stroke surveillance, and established stroke systems of care are the path to bridging the gaps in stroke care.