High Flow Research Articles

Microbial communities change along the 300 km length of the Grand River for extreme high- and low-flow regimes.

The Grand River watershed is the largest catchment in southern Ontario. The river's northern and southern sections are influenced by agriculture, whereas central regions receive wastewater effluent and urban runoff. To characterize in-river microbial communities, as they relate to spatial and environmental factors, we conducted two same-day sampling events along the entire 300 km length of the river, representing contrasting flow seasons (high flow spring melt and low flow end of summer). Through high-throughput sequencing of 16S rRNA genes, we assessed the relationship between river microbiota and spatial and physicochemical variables. Flow season had a greater impact on communities than spatial or diel effects and profiles diverged with distance between sites under both flow conditions, but low-flow profiles exhibited higher beta diversity. High-flow profiles showed greater species richness and increased presence of soil and sediment taxa, which may relate to increased input from terrestrial sources. Total suspended solids, dissolved inorganic carbon, and distance from headwaters significantly explained microbial community variation during the low-flow event, whereas conductivity, sulfate, and nitrite were significant explanatory factors for spring melt. This study establishes a baseline for the Grand River's microbial community, serving as a foundation for modeling the microbiology of anthropogenically impacted freshwater systems affected by lotic processes.

Heated humidified high-flow nasal cannula: a new conservative approach for neonatal nasal stenosis.

The aim of this study is to evaluate the efficacy of heated humidified high flow nasal cannula (HFNC) therapy as a conservative treatment option for newborns suffering from nasal stenosis, a condition that often leads to respiratory distress and feeding difficulties. Given the increasing utilization of HFNC in various upper and lower respiratory tract indications, characterized by its flow-based mechanism and minimal mucosal damage, we seek to investigate its potential benefits in this specific patient population. A retrospective chart review of newborns with congenital nasal stenosis treated with HFNC for respiratory distress or feeding difficulties in a pediatric tertiary center between 2014 and 2022. Data were collected for demographic characteristics, clinical presentation and ventilatory requirements, pre and post HFNC application. Six infants with nasal stenosis were included in the study cohort. Five were diagnosed with congenital pyriform aperture stenosis, three of whom had additional midnasal stenosis. One patient had nasal synechiae. Two patients had failed surgical treatment and all patients failed conservative treatment prior to HFNC treatment. Following HFNC use, improvement was noted in oxygen saturations, heart and respiratory rates, meal volumes and weight. None of the patients required any additional sinonasal surgical treatment. No complications were observed. In this case series, we present the first documented use of HFNC treatment for nasal stenosis, showing favorable results. Further studies with a larger cohort, wider range of conditions and extended follow-up periods are needed to establish the risks and benefits of HFNC for neonatal nasal stenosis.

Evolution and genetic characterization of Seoul virus in wild rats Rattus norvegicus from an urban park in Lyon, France 2020-2022.

Seoul virus (SEOV) is an orthohantavirus primarily carried by rats. In humans, it may cause hemorrhagic fever with renal syndrome (HFRS). Its incidence is likely underestimated and given the expansion of urban areas, a better knowledge of SEOV circulation in rat populations is called for. Beyond the need to improve human case detection, we need to deepen our comprehension of the ecological, epidemiological, and evolutionary processes involved in the transmission of SEOV. We performed a comprehensive serological and molecular characterization of SEOV in Rattus norvegicus in a popular urban park within a large city (Lyon, France) to provide essential information to design surveillance strategies regarding SEOV. We sampled rats within the urban park of 'La Tête d'Or' in Lyon city from 2020 to 2022. We combined rat population genetics, immunofluorescence assays, SEOV high-throughput sequencing (S, M, and L segments), and phylogenetic analyses. We found low structuring of wild rat populations within Lyon city. Only one sampling site within the park (building created in 2021) showed high genetic differentiation and deserves further attention. We confirmed the circulation of SEOV in rats from the park with high seroprevalence (17.2%) and high genetic similarity with the strain previously described in 2011 in Lyon city. This study confirms the continuous circulation of SEOV in a popular urban park where the risk for SEOV transmission to humans is present. Implementing a surveillance of this virus could provide an efficient early warning system and help prepare risk-based interventions. As we reveal high gene flow between rat populations from the park and the rest of the city, we advocate for SEOV surveillance to be conducted at the scale of the entire city.

A Performance Analysis of a Two Way Stop Control (TWSC) Intersection under Mixed Traffic Conditions

Intersections are road traffic infrastructure on highways installed to help settle directional movement that could result in conflict while vehicular trips are made. Evaluation of the challenges faced by different automobile users at the Araromi junction (A three Leg at-grade Intersection) located in Akure is the main objective of this paper. To achieve this objective, traffic flow data were collected on the spot by video recording and then the data were manually counted. While, the highway Capacity manual 2010 methodology was adopted to analyse The entry flow rates, Potential Capacities, Movement Capacities, Movement Control Delay, Approach Intersection Control and 95th Percentile Quene Length of the intersection. Findings shows that an average entry flow rate of 357 pc/h occurs for all the legs of the intersection, the North bound left turning movement of the intersection was not within the allowable limit, the average potential capacity by lane for the intersection is 445 pc/h, and the average movement capacity by lane 473 Pc/h, the various legs of the intersection has a level of service of ‘A’ and ‘C’ except the left turning minor street movement that has an ‘F’ LOS. Due to the influence of high traffic flow around the intersection, the analysis of the real-time traffic flow results reveals the need to diverge the high right turning movement into other route to cater for low left turning movement causing delay and poor LOS and a need to introduce Signal on the intersection in other to improve on her functionality.

Benthic macroinvertebrate response to estuarine emergent marsh restoration across a delta-wide environmental gradient

Benthic invertebrates play vital roles in estuarine ecosystems, but like other taxa they have been excluded from former marshlands by diking and land use conversion. Dike removal is one way of restoring marsh, but the response of benthic invertebrates has been little studied. Also understudied is variation in benthic invertebrate communities across entire deltas, particularly in the Pacific Northwest of North America where deltas receive high flows and sediment loads for their size. Our goals were to evaluate invertebrate response to large-scale dike removal on the Nisqually River Delta in Puget Sound, Washington, U.S.A., characterize delta-wide invertebrate community variation, and relate invertebrate response and spatial variation to environmental conditions. We sampled invertebrates annually from one year before to three years after dike removal in restoring marsh, previously restored marsh, undisturbed reference marsh, and adjacent tidal flats. Marine taxa immediately colonized the area recently restored to tidal inundation and population size grew exponentially thereafter for several of them. Community composition and diversity recovered completely, and density and biomass were approaching recovery three years later. Invertebrate communities converged between restoring and pre-existing marsh (previously restored and reference), suggesting an influence of reestablished connectivity. Just offshore from the dike line, invertebrates declined one year after dike removal but then rebounded indicating resilience to short-term disturbance. Dike removal effects were not detected farther offshore. Near the offshore edge of the delta, invertebrate biomass and body size were greater than elsewhere and a diverse assemblage of crustaceans, polychaetes, and bivalves was present. Farther inshore, tidal flats were dominated by a few species of small-bodied polychaetes and had higher density but lower biomass and diversity. Facultative detritivores, which can also filter feed, were the dominant feeding guild everywhere on the tidal flats. Density, biomass, diversity, and community composition on the marsh were more similar to the inner than outer tidal flats. Environmental variables most associated with invertebrate community variation were elevation, salinity, and sediment grain size and organic content. Our results are relevant to assessing performance and setting expectations for future restorations and have broad implications for the role of benthic invertebrates in estuarine ecosystems.

Evaluation of various obturation techniques with bioceramic sealers in 3D-printed C-shaped canals

This in vitro study compared various obturation techniques with bioceramic sealers for filling C-shaped 3D-printed replicas. A mandibular molar with a C-shaped root canal with a C1 configuration was obtained. After instrumenting with M3 Pro Gold files (United Dental, Shanghai, China) up to size #30/0.04, a CBCT scan of the tooth was taken. Sixty 3D-printed replicas of the tooth were created. The samples were obturated with EndoSeal TCS sealer (E. TCS; Maruchi, Wonju, Korea) or EndoSeal MTA (E. MTA; Maruchi, Wonju, Korea) (n = 30). The samples in each group were obturated with the following techniques (n = 10): (1) single-cone technique (SC), (2) SC with ultrasonic activation (UA), and (3) cold hydraulic compaction (CHC). Following incubation, the replicas’ apical, middle, and coronal thirds were inspected under a digital microscope, and the proportion of filling material and void were calculated. Also, the obturation time and sealer extrusion were recorded. Data were analyzed using ANOVA, LSD post-hoc, and the chi-square tests (α = 0.05). The results indicated that in the apical third, E. TCS-SC, E. TCS-UA, and E. MTA-UA had the lowest void percentage among groups (p < 0.05). In the middle thirds, samples obturated with E. TCS-UA showed a significantly lower void percentage among all groups (p < 0.05). However, in the coronal third, E. TCS-CHC showed the least void percentage (p < 0.05), followed by E. TCS-UA and E. MTA-CHC. The E. TCS-SC and E. TCS-UA were the least time-consuming methods (p < 0.05). Sealer extrusion significantly differed among the groups, with E. MTA-UA and E. TCS-UA showing higher incidence (p = 0.019). It was concluded that E. TCS-UA was the most convenient obturation technique. However, care must be taken when obturating the canals with high flow and ultrasonic activation near the vital anatomical landmarks.

Long‐term environmental flows restore benthic invertebrate communities in a highly regulated river

The construction of dams and other in‐stream structures for human use has altered river ecosystems worldwide. Dams degrade rivers, and environmental flow releases aim to mitigate flow alterations and restore rivers downstream of dams by returning elements of the pre‐regulation flow regime, resulting in an ecosystem that resembles a more natural state. We examined the responses of benthic invertebrate communities in riffles and pool‐edge habitats to an environmental flow regime (EFR) in the highly regulated Snowy River over 17 years (2000–2016). Benthic invertebrate communities significantly changed in response to prolonged increases in the magnitude of all components of the flow regime. The composition of the benthos in the regulated river became more dissimilar to pre‐EFR communities and more closely resembled those of nearby unregulated rivers. These changes were apparent in both riffle and pool‐edge habitats and were most pronounced when flow magnitudes were highest. Scrapers increased as flows increased, and in contrast, the relative abundances of gatherers declined with prolonged high flows and could be attributed to increased daily flows and high flow events mobilizing fine sediment and scouring benthic substrates. These results indicated that the EFR altered abiotic conditions or resources that previously limited invertebrate abundances, facilitating changes to the benthic community. Community changes we observed were in response to a flow regime that remained drastically lower than natural, demonstrating that restoration targets can be achieved with small flow increases that mimic natural flow patterns.

Role of High Flow Nasal Cannula as a Novel Therapy for Treatment of Severe Obstructive Sleep Apnea in a Child With Neuroendocrine Hyperplasia of Infancy: A Case Report and Review of Literature

Role of High Flow Nasal Cannula as a Novel Therapy for Treatment of Severe Obstructive Sleep Apnea in a Child With Neuroendocrine Hyperplasia of Infancy: A Case Report and Review of Literature

Refining ICESAT-2 ATL13 Altimetry Data for Improving Water Surface Elevation Accuracy on Rivers

The application of ICESAT-2 altimetry data in river hydrology critically depends on the accuracy of the mean water surface elevation (WSE) at a virtual station (VS) where satellite observations intersect solely with water. It is acknowledged that the ATL13 product has noise elevations of the adjacent land, resulting in biased high mean WSEs at VSs. Earlier studies have relied on human intervention or water masks to resolve this. Both approaches are unsatisfactory solutions for large river basins where the issue becomes pronounced due to many tributaries and meanders. There is no automated procedure to partition the truly representative water height from the totality of the along-track ICESAT-2 photon segments (portions of photon points along a beam) for increasing precision of the mean WSE at VSs. We have developed an automated approach called “auto-segmentation”. The accuracy of our method was assessed by comparing the ATL13-derived WSEs with direct water level observations at 10 different gauging stations on 37 different dates along the Lower Murray River, Australia. The concordance between the two datasets is significantly high and without detectable bias. In addition, we evaluated the effects of four methods for calculating the mean WSEs at VSs after auto-segmentation processing. Our results reveal that all methods perform almost equally well, with the same R2 value (0.998) and only subtle variations in RMSE (0.181–0.189 m) and MAE (0.130–0.142 m). We also found that the R2, RMSE and MAE are better under the high flow condition (0.999, 0.124 and 0.111 m) than those under the normal-low flow condition (0.997, 0.208 and 0.160 m). Overall, our auto-segmentation method is an effective and efficient approach for deriving accurate mean WSEs at river VSs. It will contribute to the improvement of ICESAT-2 ATL13 altimetry data utility on rivers.

Curie point depth, thermal gradient and heat flow along the Ethiopia Rift System and adjacent plateaus using spectral evaluation approach: implications for geothermal resources

The Ethiopia Rift System (ERS) is a section of the East African Rift System within Ethiopia extending from the Afar in the northeast to the Kenya border in the southwest. It is apparent that magmatism and magmatic intrusions influence the crustal shape in the ERS resulting in its thinning and the shallowing of magmatic sources at various locations within it. As a consequence, more than 31 volcanoes hosting hydrothermal structures with a conceivable potential to generate massive quantities of geothermal energy have been identified along the ERS. In this study, we map the Curie Point Depth (CDP) over the ERS based on the analysis of aeromagnetic data extracted from the World Digital Magnetic Anomaly Map. Spectral evaluation method was used to estimate the boundaries (top and bottom) of the magnetized crust. Reduced-to-pole (RTP) aeromagnetic records have been divided into 105 (50% overlap) square blocks of 200 × 200 km size. The Curie temperature (580 °C) of magnetite was used to determine the thermal gradient and the heat drift in the area. The depths obtained for the bottom of the magnetized crust are assumed to correspond to the Curie Depths, where the magnetic layer loses all its magnetization. The determined values of Curie Point Depth, geothermal gradient and heat flow for the 50% overlapped 105 blocks, respectively, range from 8.85 to 55.85 km, 10.38 to 65.54 °C/km and 25.96 to 163.84 mW/m2. Lower CPD (< 20 km) in the ERS was obtained between Mille and Gewane (southwest Afar), between Adama (Nazret) and Yerer (NMER) and between Wendo Genet and Koti (SMER) localities. These areas, showing low CPD, exhibit excessive geothermal gradient and high heat flow all of which indicate the presence of significant geothermal potential.

Does online high-volume hemodiafiltration offer greater efficiency and sustainability compared to high-flux hemodialysis? A detailed simulation analysis anchored in real-world data

Abstract Recent findings, including the CONVINCE study report, suggests the superiority of high-volume hemodiafiltration over high-flux hemodialysis in improving patients’ outcomes. Despite positive patient outcomes, concerns have arisen about the potential negative environmental impact of high-volume hemodiafiltration, as it may lead to increased water and dialysis fluid consumption and higher waste production. In this manuscript, we address the environmental impact of high-volume HDF, focusing on three key factors: water treatment consumption, dialysis fluid consumption, and solute efficiency markers of HD and HDF. By optimizing HDF prescription through adjustments in operational capabilities, such as reducing the QD/QB ratio to 1,2 rather than 1,5 and incorporating automated ultrafiltration and substitution control, it has been demonstrated that HDF delivers a higher dialysis dose for small and middle-molecule uremic compounds with the same dialysis fluid consumption and at equal dialysis doses dialysis fluid consumption is reduced. This finding is supported by real-world data from 26 031 patients who underwent high-volume postdilution hemodiafiltration at a reduced dialysis flow (550 ml/min) and achieved an effective OCMKt/V of 1.70. In addition, simulation modeling calculations, using blood extraction coefficient, dialysate saturation coefficient, and solute clearances with urea (small MW) and ß2M (middle MW), consistently show postdilution HDF's superiority to HD. This holds true even with a significant reduction in dialysis flow down to 440 ml/min reflecting QD/QB ratio of 1,2. Postdilution HDF generates high ultrafiltrate flow (up to 35% of blood flow), delivering saturated ultrafiltrate to the lower solute concentration containing effluent dialysate, thus enhancing solute clearance which opens the way to reduce the dialysis flow. In conclusion, our analysis, combining simulation and real-world data, suggests that postdilution HDF could be a more environmentally friendly treatment option compared to conventional hemodialysis. Additionally, automated user-friendly functions that minimize dialysis fluid use, can further strengthen this environmental benefit while enhancing efficiency.

Frequency curves of high and low flows in intermittent river basins for hydrological analysis and hydraulic design

AbstractUpper and lower percentiles of Flow Duration Curves (FDCs) of daily streamflow data were investigated to develop frequency curves. Upper percentiles with exceedance probability of 1, 5 and 10% (Q1, Q5, Q10) were used for high flows, and lower percentiles with non-exceedance probability of 10, 5 and 1% (Q90, Q95, Q99) for low flows. Median value (Q50) was covered to represent the average conditions of streamflow. A mixed frequency analysis based on the total probability theorem taking zero values into account was applied for the lower percentiles of FDC. Case studies were performed for three intermittent Streamflow Gauging Stations (SGSs) from Kucuk Menderes River Basin in western Turkey. An overall assessment of results shows that the best-fit probability distribution function does not change from one SGS to another considerably for low flows while each SGS has its own probability distribution function for high flows. Upper and lower percentiles, and median value were calculated at various return periods by using the identified probability distribution functions. The calculated values were plotted in the form of frequency curves of high flow percentiles and low flow percentiles. The frequency curves have a practically significant potential use in hydrological analysis, water resources management and hydraulic design under high and low flow conditions. They are yet open to further development for regionalization and their applicability can be extended to ungauged sites in river basins.

Drifting along: using diatoms to track the contribution of microbial mats to particulate organic matter transport in a glacial meltwater stream in the McMurdo Dry Valleys, Antarctica

Flow pulses mobilize particulate organic matter (POM) in streams from the surrounding landscape and streambed. This POM serves as a source of energy and nutrients, as well as a means for organismal dispersal, to downstream communities. In the barren terrestrial landscape of the McMurdo Dry Valleys (MDV) of Antarctica, benthic microbial mats occupying different in-stream habitat types are the dominant POM source in the many glacier-fed streams. Many of these streams experience daily flow peaks that mobilize POM, and diatoms recovered from underlying stream sediments suggest that mat-derived diatoms in the POM are retained there through hyporheic exchange. Yet, ‘how much’ and ‘when’ different in-stream habitat types contribute to POM diatom assemblages is unknown. To quantify the contribution of different in-stream habitat types to POM diatom assemblages, we collected time-integrated POM samples over four diel experiments, which spanned a gradient of flow conditions over three summers. Diatoms from POM samples were identified, quantified, and compared with dominant habitat types (i.e., benthic ‘orange’ mats, marginal ‘black’ mats, and bare sediments). Like bulk POM, diatom cell concentrations followed a clockwise hysteresis pattern with stream discharge over the daily flow cycles, indicating supply limitation. Diatom community analyses showed that different habitat types harbor distinct diatom communities, and mixing models revealed that a substantial proportion of POM diatoms originated from bare sediments during baseflow conditions. Meanwhile, orange and black mats contribute diatoms to POM primarily during daily flow peaks when both cell concentrations and discharge are highest, making mats the most important contributors to POM diatom assemblages at high flows. These observations may help explain the presence of mat-derived diatoms in hyporheic sediments. Our results thus indicate a varying importance of different in-stream habitats to POM generation and export on daily to seasonal timescales, with implications for biogeochemical cycling and the local diatom metacommunity.

Effects of acute carbon monoxide posioning on liver damage and comparisons of related oxygen therapies in a rat model

Acute carbon monoxide (CO) poisoning may cause liver damage and liver dysfunction. Therefore, in this study, we aimed to compare the efficiency of normobaric (NBO) and high flow nasal cannula oxygen (HFNCO) treatments on liver injury. For that purpose, twenty-eight male Wistar albino rats were divided into four groups (Control, CO, CO + NBO, CO + HFNCO). The control group was allowed to breath room air for 30 min. Acute CO poisoning in CO, CO + NBO, CO + HFNCO was induced by CO exposure for 30 min. Thereafter, NBO group received 100% normobaric oxygen with reservoir mask for 30 min. HFNCO group received high-flow oxygen through nasal cannula for 30 min. At the end of the experiment, all animals were sacrificed by cardiac puncture under anesthasia. Serum liver function tests were measured. Liver tissue TAS, TOS and OSI levels, tissue histomorphology and immunoexpression levels of Bax, Caspase 3, TNF-α, IL-1β, and NF-κB were also examined. Our observations indicated that acute CO poisoning caused significant increases in blood COHb, serum AST, ALT, ALP, total protein, albumin, globulin levels but a decrease in albumin to globulin ratio (all, p < 0.05). Furthermore, acute CO poisoning significantly increased the OSI value, and the immunoexpresssion of Bax, Caspase 3, TNF-α, IL-1β, and NF-κB in liver tissue (all, p < 0.05). These pathological changes in serum and liver tissue were alleviated through both of the treatment methods. In conclussion, both the NBO and HFNCO treatments were beneficial to alleviate the acute CO poisoning associated with liver injury and dysfunction.

A one-dimensional model of air-cooled proton exchange membrane fuel cell stack integrating fan arrangement and operational characteristics

Air-cooled proton exchange membrane fuel cell stack’s performance can be greatly affected by the arrangement and operational characteristics of the fans that generate the air flow. However, the influence mechanisms are complex and poorly understood. In this study, a one-dimensional analytical model specifically for air-cooled stacks integrating important fan features is developed to quickly (e.g. within 5 min for a 100-cell stack) and accurately predict the water and thermal states inside stacks and stack performance under various fan arrangements and operational characteristics. The model accuracy was validated against the experimental results of a 95-cell air-cooled stack, including the stack polarization curves, temperature distribution and air flow rates at different fan’s duty cycles. The model results showed that for high air flow resistance stacks, the air flow rate and maximum net power for fans arrangement in series are higher than those in parallel by about 10% and 0.5%, respectively. Moreover, integrating a single large fan can be better than two small fans as the former induces a higher air flow rate and static pressure. On the other hand, altering the air flow channel length or depth changes the air flow resistance in stacks, leading to a shift of the working point for a fixed fan at a certain duty cycle and greatly influencing stack performance. This one-dimensional air-cooled stack model can be a powerful tool to facilitate stack design and optimization.

Design and Characterization of Highly Diffusive Turbine Vanes Suitable for Transonic Rotating Detonation Combustors

In rotating detonation engines the turbine inlet conditions may be transonic with unprecedented unsteady fluctuations. To ensure an acceptable engine performance, the turbine passages must be suited to these conditions. This article focuses on designing and characterizing highly diffusive turbine vanes to operate at any inlet Mach number up to Mach 1. First, the effect of pressure loss on the starting limit is presented. Afterward, a multi-objective optimization with steady RANS simulations, including the endwall and 3D vane design is performed. Compared to previous research, significant reductions in pressure loss and stator-induced rotor forcing are obtained, with an extended operating range and preserving high flow turning. Finally, the influence of the inlet boundary layer thickness on the vane performance is evaluated, inducing remarkable increases in pressure loss and downstream pressure distortion. Employing an optimization with a thicker inlet boundary layer, specific endwall design recommendations are found, providing a notable improvement in both objective functions.

An Analytic Element Model for Seepage Forces in Fractured Media

AbstractThere are many situations where groundwater flow has high flow rates, causing large seepage forces. Examples are flows around highly conductive fractures and tunnels. We present a new analytic element for a tunnel in an elastic medium. We combined the analytic element method for groundwater flow with that for linear elasticity, and include the seepage force as a body force in the linearly elastic model. We represent tunnels and fractures as analytic elements. The solution for the case considered is limited to steady state flow and fluid-to-solid coupling. We present examples of the computed seepage forces around a tunnel and a fracture as well as a comparison with another numerical model.

Broadleaf afforestation impacts on terrestrial hydrology insignificant compared to climate change in Great Britain

Abstract. Widespread afforestation has been proposed internationally to reduce atmospheric carbon dioxide; however, the specific hydrological consequences and benefits of such large-scale afforestation (e.g. natural flood management) are poorly understood. We use a high-resolution land surface model, the Joint UK Land Environment Simulator (JULES), with realistic potential afforestation scenarios to quantify possible hydrological change across Great Britain in both present and projected climate. We assess whether proposed afforestation produces significantly different regional responses across regions; whether hydrological fluxes, stores and events are significantly altered by afforestation relative to climate; and how future hydrological processes may be altered up to 2050. Additionally, this enables determination of the relative sensitivity of land surface process representation in JULES compared to climate changes. For these three aims we run simulations using (i) past climate with proposed land cover changes and known floods and drought events; (ii) past climate with independent changes in precipitation, temperature, and CO2; and (iii) a potential future climate (2020–2050). We find the proposed scale of afforestation is unlikely to significantly alter regional hydrology; however, it can noticeably decrease low flows whilst not reducing high flows. The afforestation levels minimally impact hydrological processes compared to changes in precipitation, temperature, and CO2. Warming average temperatures (+3 °C) decreases streamflow, while rising precipitation (130 %) and CO2 (600 ppm) increase streamflow. Changes in high flow are generated because of evaporative parameterizations, whereas low flows are controlled by runoff model parameterizations. In this study, land surface parameters within a land surface model do not substantially alter hydrological processes when compared to climate.

A Grid-based Framework for Managing Autonomous Vehicles' Movement at Intersections

With a full fleet of autonomous vehicles (AV) in the future, the concept of signal-free intersections has attracted transportation researchers. Multiple studies have investigated different methods and protocols to facilitate vehicle decision-making at intersections. Most of these methods have relied on strong centralized or inter-vehicle communications. This research aims to develop a new protocol for managing vehicle movement at four-leg intersections assuming a fully automated fleet. The main concept of the proposed protocol is to maintain a continuous movement of vehicles entering the intersection, without stopping in queues, by controlling their sequence of movements. In the methodology a dynamic occupancy grid (DOG) approach is applied by initially dividing the intersection into dynamic grids (i.e. cells). The cells are in a virtual movement, emanating away from each lane-group without overlapping, like a gear machine. Each vehicle sits on a specific cell to traverse the intersection safely at a predetermined time. In other words, vehicles approaching an intersection must register their speed and position by certain sensors, and in return receive the appropriate acceleration and speed to finally be allocated to the suitable moving grids. The efficiency of the applied protocol was demonstrated by a practical example that presented a higher intersection capacity value exceeding the ideal saturation flow rate in some cases. This reflects the efficiency of the implemented protocol and its applicability to different low to high traffic flows. Moreover, the protocol shows more flexibility in dealing with different weather, geometric and traffic conditions.

Surgical management of omega deformity in a patient with neurofibromatosis type 1: a case report.

To describe the surgical treatment in a patient with a partial omega deformity in the thoracic spine with neurofibromatosis type 1. The patient was a 55-year-old man with an omega deformity, which is defined as a curvature in which the end vertebra is positioned at the level of, above, or below the apical vertebra (i.e., a horizontal line bisecting it). We performed halo gravity traction (HGT) for 7weeks, followed by posterior spinal instrumented nearly equal in situ fusion from T2-L5 with three femoral head allografts and a local bone autograft. We avoided reconstruction of the thoracic anterior spine because of his severe pulmonary dysfunction. HGT improved the % vital capacity from 32.5 to 43.5%, and improved the Cobb angle of the kyphosis from > 180° before traction to 144° after traction. The Cobb angle of kyphosis and scoliosis changed from > 180° preoperatively to 155° and 146°, respectively, postoperatively, and 167° and 156°, respectively, at final follow-up. His postoperative respiratory function deteriorated transiently due to bilateral pleural effusions and compressive atelectasis, which was successfully treated with a frequent change of position and nasal high flow for 1week. At final follow-up, his pulmonary function improved from 0.86 to 1.04L in VC, and from 32.5 to 37.9% in %VC. However, there was no overall improvement in preoperative distress following surgery, although his modified Borg scale improved from 3 preoperatively to 0.5 postoperatively. One month after discharge, he felt worsening respiratory distress (SpO2:75%) and was readmitted for pulmonary hypertension for 2months. He was improved by non-invasive positive pressure ventilation (biphasic positive airway pressure) for 1week, medication and daily lung physiotherapy. Thereafter, he has been receiving permanent daytime (0.5L/min) and nighttime (2L/min) oxygen therapy at home. A solid arthrodesis through the fusion area was confirmed on computed tomography. However, the kyphosis correction loss was 12° (i.e., 155°-167°), while the scoliosis correction loss was 10° (i.e., 146°-156°) at 2years of recovery. We suggest that nearly equal in situ fusion is a valid option for preventing further deformity deterioration and avoiding fatal complications.