High Cognitive Demand Research Articles

The Contribution of Sustained Attention and Response Inhibition to Reading Comprehension Among Japanese Adolescents.

Previous studies demonstrated the influential role of sustained attention in the reading comprehension of alphabetic writing systems. However, there is limited understanding of how these cognitive functions contribute to reading comprehension in non-alphabetic systems, such as Japanese. This study seeks to explore this gap, focusing on how sustained attention and response inhibition function in a writing system where some of the characters represent meanings rather than sounds, introducing another layer of difficulty in the complex process of reading; Methods: Seventy-five Japanese 9th grade students performed a task to assess sustained attention and response inhibition. The cognitive test was carried out using tablets to enable feasible parallel group administration while maintaining high comparability with ecological classroom settings. Reading comprehension was measured using an exam that the participants took as part of their educational routine; Results: Our results indicate that both sustained attention and response inhibition significantly contributed to the reading comprehension of Japanese 9th grade students; Conclusions: These results replicate and expand previous studies documenting the contribution of sustained attention on the reading comprehension of alphabetic writing systems to a non-alphabetic system. Moreover, our findings unravel another important cognitive factor, namely response inhibition in reading comprehension. We suggest that response inhibition may play a crucial role in reading non-alphabetic writing systems that pose high cognitive demands, such as Japanese.

Advances in VNS efficiency and mechanisms of action on cognitive functions.

This systematic review aims to comprehensively analyze the efficacy and underlying mechanisms of vagus nerve stimulation (VNS) in enhancing cognitive functions and its therapeutic potential for various cognitive impairments. The review focuses on the impact of VNS on emotional processing, executive functions, learning, memory, and its clinical applications in conditions such as epilepsy, depression, Alzheimer's disease, and other neurological disorders. A systematic search of electronic databases (PubMed, Scopus, Web of Science) was conducted using the keywords "vagus nerve stimulation," "cognitive enhancement," "emotional processing," "executive function," "learning and memory," "epilepsy," "depression," "Alzheimer's disease," "neurological disorders," "attention-deficit/hyperactivity disorder," "sleep disorders," and "long COVID." The inclusion criteria encompassed controlled trials, longitudinal studies, and meta-analyses published in English between 2000 and July 2024. A comprehensive review of 100 articles highlighted the cognitive effects of Vagus Nerve Stimulation (VNS). Studies show that VNS, especially through transcutaneous auricular VNS (taVNS), enhances emotional recognition, particularly for facial expressions, and improves selective attention under high cognitive demands. Additionally, VNS enhances learning and memory, including associative memory and spatial working memory tasks. In clinical applications, VNS exhibits promising benefits for improving cognitive functions in treatment-resistant epilepsy, depression, and Alzheimer's disease. VNS represents a promising therapeutic approach for enhancing cognitive function across diverse patient populations. The reviewed evidence highlights its efficacy in modulating cognitive domains in healthy individuals and improving cognition in neurological conditions. However, the comparative effectiveness of different VNS modalities and the differential effects of online versus offline VNS on cognitive psychology require further investigation. Future research should focus on optimizing VNS protocols and elucidating specific cognitive domains that benefit most from VNS interventions. This ongoing exploration is essential for maximizing the therapeutic potential of VNS in clinical practice.

Comparative effects of open-skill and closed-skill sports on executive function in university students: a 16-week quasi-experimental study.

Previous reviews have often concluded that open-skill sports are more effective at enhancing executive function (EF) than closed-skill sports. However, this conclusion may not hold for closed-skill sports with high cognitive demands, such as golf. This study aimed to compare the effects of football (open-skill) and golf (closed-skill) training on enhancing EF in university students. Using a quasi-experimental, pre-post test design, 63 male participants were assigned to three groups: football (n = 21), golf (n = 21), and a sedentary control group (n = 21). Over 16 weeks of training, the intervention groups engaged in four 90-min training sessions per week, while the control group attended one 80-min physical education class per week. Assessments were conducted before and after the intervention. EFs, including inhibition control and working memory, were assessed using the Flanker task and Corsi-block tapping task, respectively. Cardiovascular fitness (CRF) was measured by the multi-stage fitness test. The golf group showed significant improvements in inhibition control from pre- to post-intervention (p = 0.02, d = 0.26), while the football and control groups did not exhibit significant changes. Post-intervention comparisons indicated no significant differences in EF performance between the golf and football groups; however, both outperformed the control group (golf, p = 0.002, d = 0.99; football, p = 0.01, d = 0.67). No significant improvement was observed in working memory for any group. Additionally, changes in CRF were not significantly correlated with EF performance. This study provides preliminary evidence that golf, a closed-skill sport with high cognitive demands, can effectively improve inhibitory control after 16 weeks of training. This improvement is comparable to that observed in football, an open-skill sport. The findings also suggest that the cognitive demands of the sports, rather than improvements in physical fitness, may be primarily responsible for the enhancements in EF.

An examination of the cognitive demand levels posed by problems in the middle grades mathematics textbooks

This research investigated the cognitive demand levels of mathematics tasks within the middle school mathematics textbooks endorsed by the Ministry of National Education for the academic year of the 2023-2024. To achieve this, a qualitative research method was utilized, and document analysis was performed. In this direction, the textbooks were analyzed using descriptive analysis. The tasks within the textbooks were examined through the lens of Smith and Stein’s (1998) theoretical framework. The findings indicate that the majority of mathematics tasks in middle school mathematics textbooks exhibit a low level of cognitive demand. It was found that over 80% of the tasks fell into the categories of memorization and procedures without connections levels. It has been revealed that tasks at the levels of procedures with connections and doing mathematics, which are high cognitive demand levels, are uncommon. This shows that textbooks do not sufficiently support the potential of students to develop mathematical thinking and problem-solving skills. Based on these results, various suggestions have been made for textbooks. The most important of these suggestions include ensuring that students are cognitively exposed to higher level tasks and increasing the number of tasks that will improve their mathematical thinking skills. Thus, it will be possible for students to have a more effective learning process by deepening their mathematical understanding.

A new injury prevention program ‘FUNBALL’ improves cognitive performance of young football (soccer) players: A cluster randomized controlled trial

The youth football injury prevention program ‘FUNBALL’ contains exercises requiring high cognitive demands, which are performed concurrently to the training of the respective motor task. This study evaluates whether the program increases cognitive performances of young football players.1253 football players (aged 13–19 years old) were randomly assigned to either a control (CON) or an intervention (INT) group. The INT group performed the ‘FUNBALL’ program at least twice per week in their training sessions for one season (9 months). The CON group continued their training routine. From the total sample, the cognitive performance of 304 players (n = 135 CON; n = 169 INT) was assessed at the beginning and the end of the season using the Cogstate® Brief Battery, with the following subtests: One Back test (accuracy), Two Back test (accuracy), One Card Learning test (accuracy), Chase Test (correct moves per second), Set Shifting (accuracy), Identification test (speed), Detection test (speed), Groton Maze Learning Test (accuracy), and Groton Maze Learning Test Delayed Recall (accuracy).A multivariate analysis of variance (MANOVA) on the cognitive performance improvements from pre-to posttest showed that the INT group improved their performances more strongly than the CON group for all cognitive tests, namely for working memory, visual learning, visual motor control, attention, psychomotor function, memory, and executive function.The present study indicates that the exercise-based injury prevention program ‘FUNBALL’ may improve the cognitive performance of young football players. Future research should include an active control group, and should investigate whether the improvement in cognition also has beneficial effects on in-game performance. Trial registration numberAsPredicted (https://aspredicted.org/2kb3b.pdf).

Measuring the Effects of Cognitive Capacity on Sentence Comprehension: Evidence From Elementary School-Age Children.

Our aim was to (a) develop a sentence comprehension measure that distinguished between cognitive capacity and syntactic knowledge in school-age children and (b) examine the relationship between comprehension performance and cognitive variables (working memory capacity and retrieval from long-term memory). We developed and administered a picture selection sentence comprehension task to 122 school-age children representing varied cognitive abilities. We evaluated comprehension accuracy and response time in two syntactically identical conditions but with different cognitive demands incorporated in picture foils-one with low demand using superfluous adjectives and another with high demand using contrastive adjectives. Children also completed tasks measuring working memory capacity and long-term memory retrieval. Comprehension accuracy was significantly lower, and response times were longer in the high-cognitive demand condition compared to the low-demand condition. Errors frequently involved incorrect attribute selection in the high-demand condition that included contrastive adjectives in picture foils, while reversal errors prevailed in the low-demand condition, which included superfluous adjectives. Accuracy correlated positively with the memory variables. Hierarchical regression analysis showed that after adjusting for comprehension in the low-cognitive demand condition (38.60% variance), memory variables accounted for 4.50% additional variance in the high-demand condition with only working memory capacity as the unique predictor. The significant role of working memory capacity in comprehending sentences with high cognitive demand indicated the recruitment of active attention and verbal rehearsal. Data support the newly developed measure's potential for assessing cognitive skills integral to sentence comprehension in school-age children. https://doi.org/10.23641/asha.26767063.

A - 27 Case Study Approach to Initial Exploration of Adaptations of Cognitive Behavioral Therapy (CBT) for Non-Epileptic Seizures (NES) in the Context of Cognitive Impairment

Abstract Objective The following case study seeks to review implementation of CBT for NES, discuss psychotherapeutic adaptations and outcomes while balancing treatment fidelity, and offer preliminary recommendations for expansion of psychotherapeutic modalities for individuals with cognitive impairment. Methods 49-year-old Hispanic male with a history of mixed epileptic (non-lesional frontal lobe medically refractory) and non-epileptic events. Neurological workup included video EEG, which captured seven events without EEG correlate and an unremarkable brain MRI. Neuropsychological evaluation indicated mild cognitive impairment due to epilepsy with deficits in processing speed, executive functioning, and confrontation naming with borderline to low average core visual and verbal abilities. The patient participated in manualized CBT for PNES. Results Treatment adaptations included extending treatment sessions from 12–19 sessions and including the patient’s sister. They read the chapters together and practiced strategies outside of session. She participated in helping him notice patterns of manifestations of fear and anger and their influence on somatic symptoms. Omission of treatment elements with higher cognitive demand (i.e., thought chart). Outcomes included increased awareness of emotions, triggers, and warnings but not episode reduction in the context of increased epileptic seizures. Conclusions Feasibility of treatment may be limited for individuals with mixed epileptic and NES episodes, particularly if there is cognitive impairment and difficulty differentiating between the two. Psychotherapeutic techniques that are concrete and behaviorally based will = be beneficial for individuals with cognitive impairment. Episode reduction in isolation is likely reductionistic when considering treatment effectiveness. Ability to self-manage episodes, quality of life, functional status, and self-efficacy are valuable markers of improvement.

Disrupted cognitive network revealed by task-induced brain entropy in schizophrenia.

Brain entropy (BEN), which measures the amount of information in brain activity, provides a novel perspective for evaluating brain function. Recent studies using resting-state functional magnetic resonance imaging (fMRI) have shown that BEN during rest can help characterize brain function alterations in schizophrenia (SCZ). However, there is a lack of research on BEN using task-evoked fMRI to explore task-dependent cognitive deficits in SCZ. In this study, we evaluate whether the reduced working memory (WM) capacity in SCZ is possibly associated with dynamic changes in task BEN during tasks with high cognitive demands. We analyzed data from 15 patients with SCZ and 15 healthy controls (HC), calculating task BEN from their N-back task fMRI scans. We then examined correlations between task BEN values, clinical symptoms, 2-back task performance, and neuropsychological test scores. Patients with SCZ exhibited significantly reduced task BEN in the cerebellum, hippocampus, parahippocampal gyrus, thalamus, and the middle and superior frontal gyrus (MFG and SFG) compared to HC. In HC, significant positive correlations were observed between task BEN and 2-back accuracy in several brain regions, including the MFG and SFG; such correlations were absent in patients with SCZ. Additionally, task BEN was negatively associated with scores for both positive and negative symptoms in areas including the parahippocampal gyrus among patients with SCZ. In conclusion, our findings indicate that a reduction in BEN within prefrontal and hippocampal regions during cognitively demanding tasks may serve as a neuroimaging marker for SCZ.

Exercise and Acute Cognitive Enhancement.

Substantial research has explored the effects of a single session of exercise on cognitive performance. Meta-analytic reviews provide summary statistics relative to these effects when the cognitive task is performed while exercising and when performed after exercise. When performed concomitantly the effects of exercise are typically small or negative with the exception of moderate effects for speed of cognitive performance during moderate intensity exercise. When cognitive performance is assessed following the cessation of exercise, the effects are typically positive. When considering the effects following exercise, most studies have focused on executive function and episodic memory as the cognitive outcomes of interest with meta-analyses supporting small-to-moderate benefits. When potential moderators related to exercise parameters or participants characteristics are examined, results suggest that 20 minutes of moderate to vigorous intensity exercise consistently benefits performance with larger effects evident for executive function tasks with higher cognitive demands, for long-term memory tasks when exercise is performed prior to information encoding, and when considering individuals with lower initial cognitive performance levels. These observed benefits are likely due to the impacts acute exercise can have on physiological arousal, brain function, and brain neurotrophic factors. Advancements in our understanding of the potential of a single session of exercise to benefit cognitive performance are important for exercise prescription and to inform chronic exercise programs designed to benefit cognition.

Lost at sea: Impact of an ocean survival experience on psychological, physiological and cognitive abilities (RAD'LÔ)

Survival in an extreme environment places high physiological and cognitive demands on the individual. These environments are characterized by specific stimuli, including unusual sensory stimulation and uncertainty, which induce intense stress. Thus, the aims of this study are: i) to evaluate the impact of a five-day survival at sea simulation on human adaptive capacities, based on the assessment of psychological, cognitive, physiological, and sensorial measures; and ii) to assess recovery. Twenty-one healthy participants were enrolled in a 5-day simulation onboard a lifeboat or an inflatable raft. Psychological, physiological, sensory, and cognitive measurements were recorded before leaving (baseline), at the end of the experiment (post) and during the week that followed (recovery). Our results are unequivocal. The harshness of the environment affected the majority of the organism's responses. On the cognitive level, performance significantly deteriorated. On the psychological level, there was low mood, a decrease in subjective exteroceptive acuity and sleep disorders, increased energy, and less perceived stress. On the physiological level, a decline was recorded with respect to autonomous nervous system measurements. On the sensory level, we observed a state of hypervigilance and hypersensitivity to stimuli from the external environment. Proprioception was deeply impacted. Moreover, at recovery, many individuals did not fully recover or deteriorated further, especially regarding sleep, interoceptive abilities and sensory distortion. It appears that participants entered a state of psychological hibernation, associated with increased physical and cognitive load, and sensory hypervigilance. These results raise the question of the risks that may be incurred during future long-term space missions, as astronauts will have to maintain their cognitive performance at a high level to be able to respond to environmental demands and remain alive. It is essential to continue to explore countermeasures that will support adaptation in future spacecraft crew.

Driven to distraction: A systematic literature review on the role of the driving context in mobile phone use

Mobile phone use is one of the most frequent causes of distraction among drivers. While there have been a significant number of studies that have examined individuals’ intentions to use a mobile phone while driving, the influence of individuals’ in-situ judgement of driving conditions has received considerably less attention. The aim of this investigation was to provide a systematic understanding of how factors associated with the driving context and environment influence a driver’s decision to engage in mobile phone use while driving. Following a systematic classification scheme, 41 research articles from the years 2011 to 2020 were reviewed and synthesised to identify the contextual determinants of mobile phone distraction. Overall, the findings provided support for the role that contextual features play in influencing individuals’ mobile phone use engagement. This finding was particularly the case in instances where mobile phone tasks required relatively high cognitive and physical demands on an individual, such as texting and/or reading mails. The findings also indicated that as contextual complexity increases, mobile phone use decreases as well. A deeper understanding of the relationship between contextual factors and phone use while driving may aid in the design of more efficient driver support systems and the development of distraction-sensitive road design guides. This understanding can also assist in the identification of mobile phone use hotspots and the improvement of law enforcement and educational strategies to prevent the behaviour.

The Mixed Role of Sleep and Time of Day in Working Memory Performance of Older Adults with Mild Cognitive Impairment.

The importance of night sleep for maintaining good physical and cognitive health is well documented as well as its negative changes during aging. Since Mild Cognitive Impairment (MCI) patients bear additional disturbances in their sleep, this study aimed at examining whether there are potential mixed effects of sleep and afternoon time of day (ToD) on the storage, processing, and updating components of working memory (WM) capacity in older adults with MCI. In particular, the study compared patients' performance in the three working memory components, in two-time conditions: "early in the morning and after night sleep", and "in the afternoon and after many hours since night sleep". The Working Memory Capacity & Updating Task from the R4Alz battery was administered twice to 50 older adults diagnosed with MCI. The repeated measures analysis showed statistically significant higher performance in the morning condition for the working memory updating component (p < 0.001). Based on the findings, it seems that the afternoon ToD condition negatively affects tasks with high cognitive demands such as the WM updating task in MCI patients. These findings could determine the optimal timing for cognitive rehabilitation programs for MCI patients and the necessary sleep duration when they are engaged in cognitively demanding daily activities.

Patterns of neural activity in prelimbic cortex neurons correlate with attentional behavior in the rodent continuous performance test.

Sustained attention, the ability to focus on a stimulus or task over extended periods, is crucial for higher level cognition, and is impaired in individuals diagnosed with neuropsychiatric and neurodevelopmental disorders, including attention-deficit/hyperactivity disorder, schizophrenia, and depression. Translational tasks like the rodent continuous performance test (rCPT) can be used to study the cellular mechanisms underlying sustained attention. Accumulating evidence points to a role for the prelimbic cortex (PrL) in sustained attention, as electrophysiological single unit and local field (LFPs) recordings reflect changes in neural activity in the PrL in mice performing sustained attention tasks. While the evidence correlating PrL electrical activity with sustained attention is compelling, limitations inherent to electrophysiological recording techniques, including low sampling in single unit recordings and source ambivalence for LFPs, impede the ability to fully resolve the cellular mechanisms in the PrL that contribute to sustained attention. In vivo endoscopic calcium imaging using genetically encoded calcium sensors in behaving animals can address these questions by simultaneously recording up to hundreds of neurons at single cell resolution. Here, we used in vivo endoscopic calcium imaging to record patterns of neuronal activity in PrL neurons using the genetically encoded calcium sensor GCaMP6f in mice performing the rCPT at three timepoints requiring differing levels of cognitive demand and task proficiency. A higher proportion of PrL neurons were recruited during correct responses in sessions requiring high cognitive demand and task proficiency, and mice intercalated non-responsive-disengaged periods with responsive-engaged periods that resemble attention lapses. During disengaged periods, the correlation of calcium activity between PrL neurons was higher compared to engaged periods, suggesting a neuronal network state change during attention lapses in the PrL. Overall, these findings illustrate that cognitive demand, task proficiency, and task engagement differentially recruit activity in a subset of PrL neurons during sustained attention.

Flexible adaptation of task-positive brain networks predicts efficiency of evidence accumulation

Efficiency of evidence accumulation (EEA), an individual’s ability to selectively gather goal-relevant information to make adaptive choices, is thought to be a key neurocomputational mechanism associated with cognitive functioning and transdiagnostic risk for psychopathology. However, the neural basis of individual differences in EEA is poorly understood, especially regarding the role of largescale brain network dynamics. We leverage data from 5198 participants from the Human Connectome Project and Adolescent Brain Cognitive Development Study to demonstrate a strong association between EEA and flexible adaptation to cognitive demand in the “task-positive” frontoparietal and dorsal attention networks. Notably, individuals with higher EEA displayed divergent task-positive network activation across n-back task conditions: higher activation under high cognitive demand (2-back) and lower activation under low demand (0-back). These findings suggest that brain networks’ flexible adaptation to cognitive demands is a key neural underpinning of EEA.

Enhancing Return to Alpine Skiing: Integrating Perceptual-Motor-Cognitive Considerations in Testing and Progressions: A Clinical Commentary.

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Delving Into the Influence of Visual Input on the Load-Related Silent Pauses During SI: What About Gestures?

This research delves into the realm of simultaneous interpreting (SI) with a focus on the Portuguese-Chinese language pair, examining the interplay between visual inputs and cognitive load. This study posits that visual cues such as hand gestures may influence the cognitive load during SI, a topic that remains controversial in interpreting studies. To address this, we conducted an empirical study involving 18 trainee interpreters divided into two groups: a control group receiving only audio input and an experimental group with additional video input. Utilizing ELAN 6.3 software, we analyzed silent pauses exceeding 300ms to gauge the cognitive load. The research focused on how audio and video inputs impact these silent pauses, with a special emphasis on segments accompanied by semantically related hand gestures. The results revealed that the average duration of silent pauses was marginally shorter for interpreters with video input, although the differences between the two groups were not statistically significant. Intriguingly, for both groups, the duration of pauses significantly increased during segments with semantically related gestures, underscoring the inherent high cognitive demand of these segments, irrespective of visual input. A notable discovery was the marked increase in fluency for participants with visual access when interpreting segments accompanied by gestures, which suggests that semantically related gestures provide cognitive benefits. Overall, this study contributes to the ongoing discourse on the role of visual inputs in SI, highlighting the potential of gesture input to alleviate cognitive load and improve interpreter performance.

Ego depletion does not negatively impact novice sprinters’ start performance during a timed 20m all-out sprint

Temporary reductions in self-control due to previous cognitive effort, also known as ‘ego depletion’, have been shown to negatively impact performance in subsequent tasks requiring self-control. Various theoretical accounts suggest that high levels of task motivation may prevent negative behavioural effects of ego depletion. Against this background, the current study performed a conceptual replication of a previous study examining the effects of ego depletion on sprint start performance (i.e., Englert et al., 2015) and implemented additional monetary incentives to manipulate task motivation. Using a pretest-intervention-posttest design, ninety-six novice sprinters performed a sprinting task that required them to complete a series of 20-m sprints. In between pretest and posttest, participants performed a letter writing task either under high cognitive demand (depletion group) or low cognitive demand (non-depletion control group). Subsequently, and prior to starting the posttest, participants were presented either with a monetary incentive or no incentive. Manipulation checks confirmed that the letter writing task successfully manipulated perceived regulatory demand and that task motivation at the posttest was higher for participants who were offered a monetary incentive. The number of false starts decreased significantly with ego depletion, while sprint start reaction times and sprint finish times remained unaffected. Regardless of ego depletion, sprint finish times significantly improved with monetary incentives. These results suggest that brief engagement in a demanding cognitive task is unlikely to impair novice sprinters’ ability to self-regulate during the start of a subsequent, maximal sprinting effort for which they are highly motivated.

Emotional Experiences During Completion of Daily Occupations in Individuals With Anxiety

The present study examined the frequency with which individuals with anxiety experienced positive and negative emotions during the completion of daily occupations. Participants were 89 individuals with a self-reported diagnosis of anxiety who completed the Emotional Experiences in Activities of Daily Living Scale (EEADLs) and State-Trait Inventory for Cognitive and Somatic Anxiety (STICSA). Individuals with high anxiety demonstrated more negative emotions but no differences in positive emotions during completion of personal care and household tasks with high physical and cognitive demands. Assessing emotions experienced during occupations can help inform recommendations to improve occupational balance and engagement in individuals with anxiety.

HD-tDCS mitigates the executive vigilance decrement only under high cognitive demands

Maintaining vigilance is essential for many everyday tasks, but over time, our ability to sustain it inevitably decreases, potentially entailing severe consequences. High-definition transcranial direct current stimulation (HD-tDCS) has proven to be useful for studying and improving vigilance. This study explores if/how cognitive load affects the mitigatory effects of HD-tDCS on the vigilance decrement. Participants (N = 120) completed a modified ANTI-Vea task (single or dual load) while receiving either sham or anodal HD-tDCS over the right posterior parietal cortex (rPPC). This data was compared with data from prior studies (N = 120), where participants completed the standard ANTI-Vea task (triple load task), combined with the same HD-tDCS protocol. Against our hypotheses, both the single and dual load conditions showed a significant executive vigilance (EV) decrement, which was not affected by the application of rPPC HD-tDCS. On the contrary, the most cognitively demanding task (triple task) showed the greatest EV decrement; importantly, it was also with the triple task that a significant mitigatory effect of the HD-tDCS intervention was observed. The present study contributes to a more nuanced understanding of the specific effects of HD-tDCS on the vigilance decrement considering cognitive demands. This can ultimately contribute to reconciling heterogeneous effects observed in past research and fine-tuning its future clinical application.

Are schematic diagrams valid visual representations of concepts? Evidence from mental imagery in online processing of English prepositions

Abstract Embodied imagery hypothesis proposes the activation of perceptual-motor systems during language processing. Previous studies primarily used concrete visual stimuli to investigate mental imagery in language processing by native speakers (NSs) and second language (L2) learners, but few studies employed schematic diagrams. The study aims to investigate mental imagery in processing prepositional phrases by English NSs and L2 learners. Using image-schematic diagrams as primes, we examine whether any mental imagery effect is modulated by target preposition (over, in), the abstractness of meaning (spatial, extended), and stimulus onset asynchrony (SOA; 1,040 ms, 2,040 ms). A total of 79 adult L2 learners and 100 NSs of English completed diagram–picture matching and semantic priming phrasal decision tasks. Results revealed interference effects on L2 processing of over phrases and under 2,040 ms SOA, but no such effects were observed in the NS group. The selective interference effects in L2 suggest different mental imagery patterns between L1 and L2 processing, and processing schematic diagram primes requires high cognitive demands, potentially leading to difficulties in integrating visual and linguistic information and making grammaticality judgments. The findings partially validate schematic diagrams as visual representations of concepts and suggest the need for further examination of schematic diagrams with varying degrees of complexity.