In this research project, a versatile procedure has been designed for the preparation of supported copper@curcumin on magnetic graphene oxide nanoparticles (GO@Fe3O4@Cur–Cu). The structure of prepared nanocatalyst was characterized by several techniques including; Fourier transform infrared, powder X-ray diffraction, thermal gravimetric analysis, energy dispersive X-ray analysis, inductively coupled plasma optical emission spectroscopy, vibrating sample magnetometer, transmission electron microscopy, and scanning electron microscopy analyses. The catalytic properties of GO@Fe3O4@Cur–Cu were examined for the efficient synthesis of polyhydroquinolines as well as the preparation of sulfoxides through selective oxidation of sulfides in the presence of hydrogen peroxide.