Herbal Toothpaste Research Articles

Formulation and Evaluation of Herbal Toothpaste

This study focuses on the formulation and evaluation of a herbal toothpaste, designed to offer an alternative to conventional chemical-based dental care products. The toothpaste was formulated using natural ingredients known for their antimicrobial, anti-inflammatory, and oral health-promoting properties, such as neem, clove, and tea tree oil. Various parameters, including pH, abrasive properties, and microbial efficacy, were assessed to ensure safety and effectiveness. The formulation was tested for its ability to reduce plaque formation, fight bacteria, and promote gum health. Results indicated that the herbal toothpaste exhibited comparable or superior performance in terms of antimicrobial activity and oral hygiene benefits, while being gentle on tooth enamel. The findings suggest that this herbal toothpaste could serve as a viable, eco-friendly alternative to traditional products in oral care

Herbal tooth gel formulations: A comprehensive review and comparative analysis for contemporary oral health practices

The shift towards natural healthcare has sparked renewed interest in herbal tooth gel formulations as alternatives to conventional oral care products. This comprehensive review explores the historical evolution, therapeutic properties, and contemporary significance of herbal tooth gels in oral health practices. Emphasizing the global trend towards natural remedies, the review delves into the efficacy of diverse herbal ingredients such as turmeric, camphor, and clove in managing oral health concerns, particularly periodontal diseases like gingivitis. Drawing from traditional practices and modern scientific research, the review highlights the advantages of herbal toothpaste formulations, including their gentle impact on teeth, absence of harmful chemicals, and diverse therapeutic properties. Moreover, the review discusses the sensory, physical, and antimicrobial properties of herbal tooth gels, examining their potential in plaque control and gingival health. By conducting a comparative analysis and evaluation of herbal elements such as neem, aloe vera, and triphala, the review highlights the increasing popularity and therapeutic possibilities of herbal toothpaste formulations in enhancing overall oral health. Amidst the prevalence of fast-paced lifestyles and common oral health issues, it's imperative to explore the extensive benefits provided by herbal tooth gels in contemporary oral healthcare. This becomes especially crucial given the rising global fascination with herbal remedies. Delving into the potential of herbal ingredients such as neem, aloe vera, triphala, guvava etc is particularly vital for addressing the challenges posed by poor oral health. Such exploration could hold promising solutions for enhancing overall oral hygiene and tackling oral health issues effectively.

Evaluation of the antimicrobial activity of chemical and herbal toothpastes on selected clinical microbial oral flora

Background: Microbes are most commonly found associated with oral diseases. Globally, researchers along with the world Health Organization (WHO) suggested that this could be due to poor oral health and encourage all individuals to practice good oral hygiene using daily oral health products. The study aimed to determine the antimicrobial effects of toothpastes, as acclaimed by the manufacturers, to selected microbial flora involved in oral infections. Methodology: The antimicrobial activity of 6 toothpastes (3 herbal and 3 chemical) was tested against 3 clinical microbial isolates; Staphylococcus aureus, Escherichia coli and Candida albicans, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of each toothpaste determined for each microbial isolate using the broth dilution method. Results: Colgate exhibited the highest inhibitory activity against S. aureus with respective MIC and MBC of 125mg/ml and 125mg/ml, followed by Oral-B with MIC and MBC of 125mg/ml and 500mg/ml, Dabur herbal with MIC and MBC of 250mg/ml and 500mg/ml, and Longrich with MIC of 500mg/ml and MBC of 1000mg/ml. Colgate and CloseUp exhibited highest inhibitory activity against E. coli with respective MIC and MBC of 125mg/ml and 500mg/ml, followed by Dabur herbal with MIC of 500mg/ml but no MBC. Colgate exhibited the highest inhibitory activity against C. albicans with respective MIC and MBC of 125mg/ml and 500mg/ml, followed by CloseUp with MIC of 500mg/ml, Longrich with MIC of 500mg/ml and MBC of 1000mg/ml, and oral-B with MIC of 500mg/ml but no MBC. Longrich and Oral-B exhibited no MIC/MBC against E. coli while Gavia charcoal exhibited no MIC/MBC against all the 3 microbial isolates at the concentrations used in the assay.Conclusion: The results obtained showed that chemically formulated toothpastes (Colgate, CloseUp and Oral-B) had higher inhibitory activity on microbial isolates than herbal toothpastes (Longrich, Dabur herbal and Gavia charcoal). This supports the manufacturers claim for the chemical toothpastes used, however, the herbal toothpastes showed little or no inhibitory effects on the microbial flora.

FORMULATION AND EVALUATION OF HERBAL TOOTHPASTE

The present study is concerned with the formulation and evaluation of herbal toothpaste, which contains various properties like tooth abrasives, tooth whitening, anti-caring, antibacterial, anti-inflammatory, desensitivity, etc. The herbal toothpaste was prepared using mango leaf extract and guava leaf extract as active ingredients, along with various excipients, which include calcium carbonate, sodium chloride, sodium lauryl sulphate, sodium benzoate, glycerine, camphor, honey and distilled water. The toothpaste was prepared by homogeneous mixing of all the excipients and the herbal extract. Four formulations were prepared using mango leaf extract as an active ingredient along with varying excipient concentrations, four formulations were prepared using guava leaf extract as an active ingredient along with varying excipient concentrations, and a polyherbal formulation consisting of four formulations containing both mango leaf extract and guava leaves extract as active ingredients along with varying excipient concentrations. The formulations were tested for various parameters such as homogeneity, abrasiveness, foamability, moisture content, Spreadability, extrudability, colour, PH, and antibacterial activity. The study concluded that polyherbal formulation showed best results and was found to be best among all batches. The polyherbal formulation, F4 showed was found to be best among all other formulations.

Evaluation of the Remineralization Potential of an Herbal Non-fluoridated Dentifrice on Carious Lesions: An In Vitro Study

Background: This in vitro study compared the remineralization potential of Dabur red (DR), a non-fluoridated herbal toothpaste, with Colgate Strong Teeth (CST), a fluoride-based toothpaste, on permanent teeth with artificially created white spot lesions. Vickers microhardness (VMH), quantitative light-induced fluorescence system (QLF), and scanning electron microscopy (SEM) were used for data analysis. Methods: Enamel samples were prepared from the buccal surface of forty-five extracted maxillary premolars and subjected to demineralization to achieve adequate fluorescence loss (ΔF). The samples were divided into DR, CST, and control groups (n=15) and underwent 21 days of pH cycling. VMH was measured at baseline and after 21 days. QLF imaging was performed on days 7, 14, and 21. One randomly selected sample from each group underwent SEM examination to compare morphological variations. The statistical analysis was conducted using SPSS 22.0. Intra-group comparisons were made with repeated measures of analysis of variance (ANOVA), and one-way ANOVA with Tukey’s post-hoc test was utilized for inter-group comparisons (P<0.05). Results: Mean VHN increased significantly in all three groups from baseline (DR=40.47, CST=41.91, control=36.42) to the 21st day (DR=119.47, CST=120.36, control=74.36) (P=0.00). Significant differences were found between the control and test groups, but not between DR and CST. No statistically significant difference was observed in ΔF at baseline and 7 days, but there were significant differences among the groups at 14 and 21 days. SEM images revealed dense mineralization for both DR and CST. Conclusion: After 21 days of in vitro remineralization, both DR and Colgate toothpaste demonstrated similar remineralizing potential as evaluated by surface MH and QLF.

Effect of medicated toothpastes and Tooth Mousse on cariogenic microbes of the oral cavity: An in vitro study.

Dental caries, commonly known as tooth decay is a widespread oral health problem mainly attributed to the activity of cariogenic bacteria, such as Streptococcus mutans and Lactobacillus species. Tooth Mousse, containing remineralizing agents, herbal and fluoride containing toothpaste with antimicrobial agents have been developed to target cariogenic bacteria. Herbal, fluoride toothpaste, and Tooth Mousse are commonly prescribed to prevent, reduce, and control dental caries. This study aims to analyze the effect of Tooth Mousse and medicated toothpastes on S. mutans and Lactobacillus acidophilus using direct contact test. L. acidophilus and S. mutans were cultured on Mueller-Hinton agar (MHA-Hi media) using sterile cotton swabs and plates were dried for 15 min. Toothpastes (Dabur Red, Pepsodent) and Tooth Mousse were used at 1:1 dilution using sterile pyrogen-free distilled water. Fifty microliter of toothpastes and Tooth Mousse were introduced into each well. The plates were incubated at 37°C for 24 h. The antimicrobial activity was evaluated by measuring the diameter of zones of inhibition (mm). The toothpaste containing fluoride (A) showed greater zone of inhibition compared to herbal toothpaste (B) whereas Tooth Mousse (C) did not show any zone of inhibition. Among herbal and fluoride toothpaste, fluoride containing toothpaste showed more zone of inhibition thereby attributing to its increased antimicrobial property on S. mutans and L. acidophilus.

Comparison of efficacy of commercially available desensitizing Toothpastes in reducing Dentin Hypersensitivity

Dentine hypersensitivity is characterized by a short sharp pain arising from exposed dentine in response to thermal, evaporative, tactile, osmotic or chemical stimuli that cannot be ascribed to any other form of dental defect. Today, multiple desensitizing toothpastes that claim superiority over each other in reducing dentin hypersensitivity are commercially available. The present study was undertaken to evaluate and compare the efficacy of three commercially available desensitizing toothpastes in reducing dentine hypersensitivity (herbal desensitizing toothpaste, desensitizing toothpaste and desensitizing toothpaste containing 8% arginine). After ethical clearance and informed consent, a total of 45 participants were recruited equally into 3 groups (Group 1: Herbal desensitizing toothpaste; Group 2: Desensitizing paste containing potassium salt; Group 3: Desensitizing toothpaste containing 8% Arginine) by a simple random sampling method. Dentine hypersensitivity was evaluated at the baseline, immediately, at 4th week and 8th week after using the assigned toothpaste. Dentine hypersensitivity was evaluated using the Schiff sensitivity score. In this study, the comparison of the efficacy of desensitizing toothpaste within group 1 at different time intervals was found to be statistically significant (p=0.004). Comparison of the efficacy of desensitizing toothpaste within group 2 and group 3 at different time intervals was found to be statistically highly significant (p=0.000). However, the comparison of the efficacy of desensitizing toothpaste between 3 groups at baseline (p=0.659), immediately (p=0.366), at the 4th week (p=0.388) and the 8th week (p=0.583) was found to be statistically nonsignificant. The present study can be useful, as it is important to assess the efficacy of various commercially available desensitizing toothpastes, since the use of desensitizing toothpastes is considered to be the primary strategy in the management of non-carious dentinal exposure causing dentinal hypersensitivity. Key Words - Dentine hypersensitivity, Herbal toothpaste, Sensitivity, Stimuli

Formulation and Evaluation of Toothpaste Combining Clove Flower Extract (Syzygium aromaticum L.) and Chamomile Flower Essential Oil (Matricaria chamomilla)

Introduction: Herbal remedies like clove and chamomile have been traditionally used for their potential oral health benefits. This study aimed to formulate and evaluate a toothpaste combining clove flower extract (Syzygium aromaticum L.) and chamomile flower essential oil (Matricaria chamomilla) for its efficacy in promoting oral hygiene. Methods: Clove flower extract was obtained through ethanol extraction, while chamomile essential oil was procured commercially. Various toothpaste formulations (F1-F3) were prepared with varying concentrations of the herbal extracts, alongside a control formulation (F0) without the extracts. The formulations underwent comprehensive evaluation, including organoleptic assessment, pH determination, homogeneity testing, and foam height analysis. Additionally, antimicrobial activity against common oral pathogens (Streptococcus mutans and Staphylococcus aureus) was assessed using the agar well diffusion method. Results: All formulations (F0-F3) exhibited acceptable organoleptic properties, pH levels within the safe range for oral use, and homogeneity. However, foam height varied among formulations, with F1-F3 showing lower foam compared to the control (F0). Notably, F2 and F3 demonstrated significant antimicrobial activity against both S. mutans and S. aureus, suggesting their potential in combating oral pathogens. Conclusion: The combination of clove flower extract and chamomile essential oil in toothpaste formulations holds promise for enhancing oral hygiene due to their antimicrobial properties. Further research is warranted to optimize foam height and explore the long-term clinical effects of this herbal toothpaste.

Physico-chemical and microbiological characterizations of an herbal toothpaste formulated with extracts of some selected medicinal plant harvested in Benin Republic

Physico-chemical and microbiological characterizations of an herbal toothpaste formulated with extracts of some selected medicinal plant harvested in Benin Republic

Comparative Evaluation of Herbal Versus Non-herbal Dentifrice in Maintaining Oral Health of Young Adults.

Dental plaque may be attributed as a precursor to various oral health problems like dental caries, periodontal disease, halitosis, etc. With an ever-increasing awareness about the adverse effects of chemical formulations, emphasis is now being laid on the usage of herbal ingredients, as they are safer for long-term use in addition to their medicinal benefits. The present study aims to assess the anti-plaque and anti-inflammatory efficacy of herbal toothpaste compared to synthetic toothpaste among 20-40-year-old patients in Bareilly, Uttar Pradesh. In this study, 130 subjects aged between 20 and 40 years with poor oral hygiene status and signs of gingival inflammation corresponding with chronic marginal gingivitis were selected. Subjects in Group 1 were prescribed herbal toothpaste (KUDOS Ayurveda), whereas patients in Group 2 were administered non-herbal toothpaste. Clinical parameters of gingival health specifically gingival index (GI), patient hygiene performance (PHP), and approximate plaque index (API) were recorded at baseline, 14 days, 28 days, and 42 days. Chi-square test, student-independent t-test, and paired t-test were performed to find significant differences in various variables between the two groups at different follow-up visits. At the end of the study, a significant reduction in GI and API scores was obtained, along with increased PHP scores.The p-value was set at 0.05, and the power of the study was set at 0.95. There was a statistically significant reduction (p < 0.05) in GI and API and an improvement in PHP scores at various time intervals in Group 1 as compared to Group 2. Conclusion: Regular application of herbal extract dentifrices for 42 days provided a significant reduction of dental plaque and improvement in overall gingival health without any adverse effects. This instilled motivation in the patients to uphold proper oral hygiene. Hence, herbal dentifrices could be prescribed as an adjunct to periodontal therapy in the maintenance phase.

Formulation, Evaluation and Comparison of Lab made Toothpaste with Marketed Brand of Toothpaste

Toothpaste is a paste or gel useful to maintain dental health and preventing dental disease like cavities and promote oral hygiene it is an abrasive that aids in removing dental plaque and food from the teeth, assists in suppressing halitosis. It contains surfactants and active ingredients (most commonly fluoride) to help prevent tooth decay (dental caries) and gum disease (gingivitis). Large amounts of swallowed toothpaste can be toxic. The aimed of current research to formulate herbal toothpaste utilizing plant extract like Neem leaves, Guava leaves. The plant extract ingredient posses the anti-bacterial and antiseptic properties. The herbal toothpaste formulated which can satisfy all the required condition to keep the mouth fresh and prevent tooth decay by bacteria. The formulated herbal toothpaste compared with marketed preparation. The formulated herbal toothpaste compared with marketed preparation. Physical examination: Colour-greenish green, smooth in nature, ph-8.2, spreadability- Good and stable formulation. The outcome of this research herbal toothpaste shows equal patronizing and engrossing passion over the marketed preparation it was consider after the comparing the marketed preparation(Colgate, Dabur Red, Dantkanti) with formulated herbal toothpaste. It has been good scope in future dental research and dental health of public.

Formulation and evaluation of toothpaste for sensitivity

Toothpastes are complex mixtures of abrasives and surfactants; anticaries agents, such as fluoride; tartar control ingredients; pH buffers; humectants (to prevent dry-out and increase the pleasant mouth feel); and binders, to provide consistency an shape. Binders keep the solid phase properly suspended in the liquid phase to prevent to the separation of the liquid phase out of the toothpaste. The dental paste preparations of clove oil tooth paste are designed using different bases for treatment of gingivitis and properties and other dental plaque. During our physicochemical evaluation studies, all the formulations were found to have PH, good tube extrudability, good spread ability and viscosity characteristics. In the current context of oral dental care, the use of toothpaste containing natural ingredients are more widely accepted in public belief than chemical-based formulations for safety and efficacy in reducing tooth decay, and preventing other dental problems that this generation is prone to. It's usually a toothpaste-used product used by all people. Toothpaste is usually used to clean tooth enamel and mouth It is also used to solve many email problems. Many dentists recommend applying toothpaste to treat diseases such as sensitivity, chronic gingivitis, etc toothpastes are used in the treatment of gum disease, bad breath, dry mouth, periodontal damage, tartar, and dental caries. To develop a stable and functionally effective toothpaste, eliminating all synthetic additives that are usually included in such Formulation is an important task. Herbal toothpastes have received a lot of attention for reducing gingivitis.Studies show mixed results about the effectiveness of these toothpastes.

Review on Herbal Toothpaste

Herbal toothpaste is also one of the products which are available in the market &amp; we can used in our daily life. People are either stick to old brands and keep trying it or buying without knowing the real effect of product. Herbal toothpaste is a paste or gel dentifrice used to clean and maintain the aesthetic and health of teeth. Toothpaste is designed to target specific issues inside the mouth, like whitening teeth, eliminating food debris, prevent from caries &amp; reducing sensitivity. Toothpaste is a part of our daily oral hygiene routine. Many dentists recommend to use herbal toothpaste to treat disorders like sensitivity and chronic gingivitis etc. In recent year dental caries is the most common health problem in the world. Azadirachta Indica also known as neem is being used in India from ancient as a toothbrush in oral hygiene. Herbal toothpaste is containing numerous herbs like Ginger, Amala, Clove, Neem, &amp; Peppermint which have the ability to remove the plaque, freshen our breath and also prevent various gum diseases. Herbal toothpaste gives the significant action like fluorinated chemical toothpaste. Fluorinated toothpaste leads to fluorosis which weaken the bone for this purpose herbal toothpaste is the best choice for adults and children. There are numerous products available in the market as anticaries and antiplaque effect. Toothpaste protects, cleans and polishes teeth. It makes oral hygiene more efficient. Review says that the herbal toothpaste contain herbs also gives same effect like chemical toothpaste

Formulation and Evaluation of Herbal Toothpaste

Dentifrices are the products which are used for oral hygiene such as freshness of mouth and to avoid tooth decay. The oral hygiene can be maintained throughout the day by using various dentifrices prepared by herbal and synthetic ingredients. In present study the toothpaste was prepared by using various herbal ingredients which possess antibacterial, antiseptic and cooling properties.

FORMULATION AND ANTIBACTERIAL ACTIVITY OF HERBAL TOOTHPASTE BASED ON ACEH TRADITIONAL MEDICINE

This research is based on Acehnese traditional medicine containing betel leaf, areca nut, kencur rhizome, gambier sap, and clove buds. Traditionally, all parts of the plant are wrapped in betel leaf folds and chewed to maintain oral health. This study aimed to incorporate these ingredients into an herbal toothpaste and test its efficacy against bacteria that cause tooth decay, such as S. mutans and E. faecalis. Extracts from betel leaf, areca nut, aromatic ginger, gambier sap, and clove buds were used in this study. Based on variations in extract concentrations, three formulations were developed: F1, F2, and F3. In addition, F0 was the toothpaste base. The herbal toothpaste was light brown in color, homogeneous, semisolid, and had a characteristic betel leaf aroma, according to the evaluation results. The final product had a pH of 7.52–8.59, viscosity of 238.9–242.3 cP, and a foam height of 20 mm (F0), 11 mm (F1), 9 mm (F2), and 6 mm (F3). These values meet the toothpaste quality standard (SNI 112-3524-1995). While F1 showed moderate inhibition against S. mutans and E. faecalis in the antibacterial test, F2 and F3, showed high inhibition against S. mutans and moderate inhibition against E. faecalis. Based on these results, the optimal formula is F3 which has a larger inhibition diameter of 12.23 mm for S. mutans and 9.10 mm for E. faecalis. This herbal toothpaste can be developed to prevent oral candidiasis and gingivitis. Keywords: herbal toothpaste, antibacterial activity, Streptococcus mutans, Enterococcus faecalis

Plants as Regular Phytochemical Sources of Dentistry - Formulation and Evaluation of Polyherbal Tooth Paste

Different plant components have been used in medicinal preparations in indigenous systems of medicine to clean teeth or treat oral diseases such as periodontal disease. Herbal toothpaste is equally as good at controlling plaque and gingivitis as dentifrices made according to standard formulas. Streptococcus mutants, out of all the examined bacteria, were shown towards the most susceptible to the created dentifrice, as evidenced by a zone inhibition (7-8 mm), followed by Escherichia coli (7 mm), as well as oral micro-biota (8mm). The created Poly-herbal dentifrice was successfully tested using a variety of industry-recognized standards to verify its high quality and physio-chemical qualities. According to the findings, the created Poly-herbal dentifrice shows promise for having antibacterial properties on both gramme-positive and gramme-negative organisms. Compared to completely synthetic dentifrice, it must be safer. For the development of Poly-herbal dentifrice to be proven safe and effective, more research is required. According to the study’s findings, herbal toothpaste is safer and has fewer side effects than synthetic preparations. It is also more commonly used in dentistry research. The toothpaste that is designed for oral hygiene and teeth shows antimicrobial activity against pathogens. The market preparation was contrasted with the formulation. Therefore, it demonstrates an equal amount of patronizing and engrossing passion for the promoted formulations. The development of herbal toothpaste has a promising future in the research of natural cures and general dental health.

Antibacterial Effects of Herbal Toothpastes and Methods of Determining These Effects

Antibacterial Effects of Herbal Toothpastes and Methods of Determining These Effects

Formulation and Physicochemical Evaluation of a Herbal Dentifrice Formulated with Myristica fragrans (Nutmeg): An In Vitro Study

Aim: Dental plaque is the primary etiological factor of two of the most commonly encountered global oral health problems; dental caries and periodontal disease. The toothbrush-dentifrice combination is an essential aid in preventing them. There are several commercial chemical toothpastes available, but as of late herbal toothpastes have become more popular amongst people. Thus, the aim of this study was to formulate a novel herbal dentifrice with Myristica fragrans (Houtt.) (nutmeg), and compare its physicochemical properties with a commercially available herbal dentifrice without nutmeg. Material and method: A pilot study was conducted wherein the toothpaste was formulated under sterile conditions using various concentrations of nutmeg, tulsi leaves powder and clove powder as the main herbal ingredients. All herbal ingredients were 100% organic and certified by the Food Safety and Standard Authority of India (FSSAI). Its properties were compared and evaluated with a commercial herbal toothpaste and the most optimum formulation was then selected to be a part of the study. The properties evaluated were organoleptic parameters (colour, texture, appearance, taste, odour), pH, foamability, abrasiveness, gritty matter, homogeneity, stability and spreadability. Results: The results revealed that in comparison to the commercial herbal toothpaste, the formulated herbal toothpaste with nutmeg exhibited improved foaming ability, abrasivity, spreadability; and comparable texture, consistency, colour, gritty matter, homogeneity and stability properties. However, it had less favourable odour and taste. Conclusion: The overall results of the research provide convincing evidence of the satisfactory physicochemical properties of the nutmeg toothpaste. However, further research is warranted to test other significant properties of the toothpaste.

Effects of Propolis-Based Herbal Toothpaste on Dentine Hypersensitivity

IntroductionThe objective of this in vitro study was to compare the effectiveness of a propolis-based herbal toothpaste with 5% sodium fluoride varnishin obstructing human dentinal tubules; Scanning electron microscopy was utilised to obtain quantitative and qulitative data on tubular obstruction. MethodsThirty-nine extracted human premolar teeth were collected. The cementum layer was removed using a water-cooled diamond bur and the smear layer using ethylenediaminetetraacetic acid (EDTA) 17%. Then, the samples were randomly divided into 3 groups (n = 13 each), as follows: group 1: dentin discs exposed to the propolis-based herbal toothpaste (Herbex); group 2: dentin discs exposed to 5% sodium fluoride varnish; and group 3: control. Then, all discs were observed and imaged in 4 non-overlapping fields by an electron microscope at 2000× magnification. The topography and number of open, closed, and semi-closed tubules were counted in all images. The data were analysed using Kruskal–Wallis test, Mann–Whitney U test, and Friedman test. The statistical analysis was performed with SPSS statistic 22.0 software, with a significance level of α = 0.05. ResultsIn pairwise comparisons of the groups considering the percentage of open, closed, and semi-closed tubules, the difference was not statistically significant between the 5% sodium fluoride varnish and propolis groups in the closed and semi-closed tubules, but it was statistically significant with the control group. Additionally, the percentage of open tubules in the propolis-based herbal toothpaste group was significantly lower than in the 5% sodium fluoride varnish and control group. ConclusionsBoth propolis-based herbal toothpaste and 5% sodium fluoride varnish is effective in blocking human dentin tubules to various extents.

Little Ironweed and Java Tea in Herbal Toothpaste Reduced Dentine Permeability: An In Vitro Study.

To determine the effect of an herbal toothpaste containing Little Ironweed and Java Tea, on reducing dentine permeability in vitro. Dentine discs from human mandibular third molars were divided into three groups and brushed with herbal toothpaste, nonherbal toothpaste, or deionized water. Each group was immersed in artificial saliva (AS) or 6% citric acid. The permeability of each dentine disc was evaluated before and after saliva or acid challenge using a fluid filtration system. The morphology of dentine discs after treatment was observed using scanning electron microscopy (SEM). The mean permeabilities were statistically analyzed using analysis of variance and Tukey's test. The nonherbal and herbal toothpaste groups demonstrated reduced dentine permeability. AS immersion decreased dentine permeability in both toothpaste groups with values lower than the control group. Dentine permeability values increased after acid immersion in the toothpaste groups and were similar to each other. SEM revealed small granular crystal-like and round particles on the dentine surface and opening of dentinal tubules of both toothpaste groups. More dentinal tubules were opened after brushing with deionized water. The reduction of dentine permeability caused by the herbal toothpaste was similar to that of the nonherbal toothpaste after brushing and the simulated oral conditions. Both herbal plants have the possibility to alleviate clinical hypersensitivity by reducing dentine permeability. Little Ironweed and Java Tea in the toothpaste composition is a potential choice for treating hypersensitive dentine.