Hemodialysis Machine Research Articles

Automation and innovation in home hemodialysis machines.

In this review, we discuss the timeline of innovation and technologic development in home hemodialysis (HHD) in the United States and the legislative approvals that accompanied them. The most recently FDA-approved home hemodialysis devices provide features that include on-demand and batch dialysate generation, access disconnect for venous needle dislodgement, touchscreen interface with visual and auditory prompts and animations, drop-in sterilized cartridges with prestrung tubing, hot water disinfection of tubing allowing extended-use, dialysate flow rates as high as 500 ml/min, as well as remote treatment monitoring capabilities. Furthermore, wearable/portable dialysis devices are currently under development to simplify dialysis delivery to patients with end-stage kidney disease. Home hemodialysis devices providing longitudinal hemodialysis across different clinical settings, virtual reality headsets for more personalized training, automated patient support, as well as wearable device development and innovations give hope for a future where home hemodialysis is more accessible and seamless.

Connected Home Hemodialysis Machine Use and Transition to In-Center Hemodialysis

Connected Home Hemodialysis Machine Use and Transition to In-Center Hemodialysis

Design a Mobile Application for the Maintenance of Hemodialysis Machines using Flutter Framework

Design a Mobile Application for the Maintenance of Hemodialysis Machines using Flutter Framework

Scattering effect for relative blood volume monitoring during hemodialysis

The long-term survival rate of hemodialysis patients is limited by hemodialysis-related complications, which are attributed to the inappropriate level of relative blood volume (RBV) after treatment. For the conventional optical monitoring methods, the RBV is usually overestimated, especially when the RBV varies in a wide range. Here, we find that the scattering effect of blood on incident light is the dominant factor of nonlinear measurement errors according to the numerical simulation results. Then a computational model considering both the absorption and scattering effect of blood is proposed and applied to a relative blood volume monitoring system (RBVMS). Finally, the RBVMS is validated in a commercial hemodialysis machine, showing a relatively low measurement error of 6.9 %. This result indicates the potential of the system for RBV monitoring during hemodialysis.

The utilization of renal dialysis: a comprehensive study in Saudi Arabia

BackgroundUnderstanding the trend of utilization of renal dialysis in Saudi Arabia (SA) is fundamental as it provides a general overview of renal care. The practice of renal dialysis assists in identifying challenges, opportunities, and potential areas for improvement in the provision of the services.ObjectivesThis research investigated the utilization of renal dialysis services in SA by exploring the number of renal dialysis centers, hemodialysis machines (HD), and peritoneodialysis patients.MethodsThe dataset for this study was derived from a collaboration between the General Authority of Statistics (GaStat) and the Ministry of Health (MoH), focusing on indicators for renal dialysis centers and patients across health sectors in 2021. Analysis was conducted using MS Excel 365 and IBM SPSS Version 29, incorporating multiple regression techniques. The health sector was treated as the dependent variable. At the same time, the number of hemodialysis (HD) machines and the counts of HD and peritoneal dialysis patients were considered independent variables.ResultsAround 275 renal dialysis centers, over 8000 HD machines, 20,440 HD patients, and 1,861 peritoneal patients were tallied from two resources. The findings revealed a negative relationship between the health sector and several renal dialysis centers and peritoneodialysis patients, as demonstrated by p < 0.05 in multiple regression analysis.ConclusionThe number of renal dialysis centers influences the availability of HD machines, affecting the number of HD and peritoneodialysis patients. Most national patients preferred MoH over other semi-governmental and private sectors, and vice versa for non-Saudis.

Highly Biocompatible Graphite Electrodes by Using Interface‐Stable Coating and the Application to Hemodialysis

AbstractIn the treatment of kidney diseases such as chronic kidney disease (CKD) and acute tubular necrosis (ATN), prolonged contact between conductivity sensors and patients' bodily fluids is required, necessitating high biocompatibility for the electrodes. However, the widely used graphite electrodes exhibit limited biocompatibility, showing a cell survival rate of only 88% under indirect contact conditions, and &lt;56% under direct contact conditions. Here, the surface detachment of graphite electrodes in liquid environments leading to cell death upon contact is observed and a solution is proposed to enhance biocompatibility and ensure conductivity, by forming a layer of interface‐stable coating (ISC) as a conductive isolation membrane on their surface. For applications with contact requirements, graphite‐like carbon (GLC) coated graphite electrodes are investigated and developed, resulting in an exceptional cell survival rate exceeding 96% under indirect contact conditions, and a relatively high survival rate exceeding 91% under direct contact conditions, both accompanied by significant proliferation. GLC‐coated graphite electrodes are successfully to monitor the dialysate conductivity in a hemodialysis machine and achieve stable monitoring with temperature compensation. The results demonstrate ISC graphite electrodes' potential in biomedical fluid monitoring, with the developed process applicable to other fields.

Design and application of a hemodialysis machine suitable for transporting patients

Blood purification is one of the commonly used techniques for the rescue of critically ill patients, which is used for acute and chronic kidney injury caused by various causes and renal replacement therapy (RRT) for a variety of critical diseases. Its main working principle is to drain the human blood into a variety of dialyzers through the artificial tube, exchange substances through a variety of ways, and remove harmful substances and some metabolites from patients' body. Then the purified blood is transfused back to the body, so as to maintain the patient's internal environment relatively stable. At present, there are different models of hemodialysis machines in clinical practice, but they are bulky and unable to move, and the method of heat dissipation is single, which cannot meet the needs of hemodialysis treatment in transport patients. Therefore, the medical staff of the Second Affiliated Hospital of Zunyi Medical University designed and developed a hemodialysis machine, which is suitable for patients who demand hemodialysis treatment during transport, and obtained the National Invention Patent of China (ZL 2020 1 0864737.3). The hemodialysis machine comprises a main body of the hemodialysis machine and a mobile vehicle. The main body of the hemodialysis machine is placed in the bottom of the mobile vehicle, and a protective cylinder with fixed airbags is designed around the main body of the hemodialysis machine. The fixed airbag is connected to the air storage tank through the pipeline, the air storage tank is connected to the Venturi tube through the control valve, and the throat of the Venturi tube is connected to the disinfection tank and cooling water tank. The outlet end of the Venturi tube is connected with the cooling pipe inside the main part of the hemodialysis machine and the sprinkler head placed on the top of the main body. By adding a mobile vehicle and designing an airbag and protective cylinder, the hemodialysis machine can be applied to the hemodialysis treatment during the transportation of patients. By designing the heat dissipation pipe, the main body of the hemodialysis machine can be cooled, the temperature of the hemodialysis machine can be reduced, and the hemodialysis machine can still work when the fan is damaged. By designing the sprinkler head, it is convenient to automatically disinfect the main screen and control keys of the hemodialysis machine, reduce the risk of cross infection of medical staff in the operation, and increase the safety and practicability of the hemodialysis machine. The hemodialysis machine is convenient, safe and efficient, which can be widely used in the hemodialysis treatment during transported patient, and is worthy of clinical promotion.

Green Nephrology - What does this mean for dialysis procedures?

In times in which climate change is becoming increasingly noticeable in the everyday lives of the global population, a rethinking towards an environmentally friendly and climate-neutral way of life is essential in all areas of human activity (including medicine). In the field of nephrology, a reorientation of resource-intensive renal replacement therapy is therefore absolutely necessary, keyword "green nephrology". To this end, awareness of the CO2 emissions caused in the field of nephrology must first be raised so that CO2 savings can then be implemented efficiently. Initially using the current conventional dialysis procedures. In addition, further technical developments such as portable and wearable haemodialysis and peritoneal dialysis machines will enable significant savings in energy and water consumption in the future. Furthermore, innovative research approaches are introducing new alternatives to organ transplantation, such as xenotransplantation, stem cell research and "artificial" organ replacement.A wide variety of promising approaches is therefore available for the renal replacement therapy of the future. The aim of nephrology must now be to drive forward further development and implement it in such a way that environmentally friendly patient care in nephrology is possible in the near future in order to make our contribution to climate protection while at the same time ensuring the treatment and its quality.

THE RELATIONSHIP BETWEEN THE LONG TIME ON HEMODIALISIS AND THE LEVEL OF DEPRESSION IN CHRONIC KIDNEY FAILURE PATIENTS IN THE HEMODIALISIS ROOM SANTOSA HOSPITAL BANDUNG CENTRAL (SHBC)

Introduction. The prevalence of depression cases in the world is around 17% of all mental disorders in society. This figure is the largest compared to other mental disorders. This condition will increase under certain conditions, for example in patients with certain medical conditions who experience chronic illnesses such as stroke, diabetes, cancer and chronic kidney failure. Patients with chronic kidney failure who are required to undergo hemodialysis will increase the risk of depression, this is caused by stressors that arise such as dependence on hemodialysis machines for life, changes in lifestyle patterns related to long periods of undergoing hemodialysis, restrictions on food and drink patterns and adaptation to disease condition. The aim of this study was to determine the relationship between the length of time undergoing hemodialysis and the level of depression in chronic kidney failure patients in the SHBC hemodialysis room. Method. This research is a quantitative correlation research with a cross sectional approach or also called a point time approach . The sampling technique used in this research was Accidental Sampling of 92 respondents using the Beck Depression Inventory (BDI) questionnaire. Result &amp; Analysis. Based on the results of statistical tests, the p-value = 0.038 (p &lt;0.05). Discussion. In this study, it can be concluded that there is a relationship between the length of time undergoing hemodialysis and the level of depression in chronic kidney failure patients in the SHBC hemodialysis room in 2022. Patients with chronic kidney failure have many stressors that arise while undergoing hemodialysis, for this reason families and nurses can provide motivation to patients with chronic kidney failure so that they can reduce the level of depression.

The Effect of Intradialytic Aerobic Exercise on Dialysis Parameters and Fatigue in Hemodialysis Patients: A Non-randomized Interventional Study.

Introduction Hemodialysis is the standard treatment for end-stage renal disease. However, patients receiving hemodialysis can become less active as a result of treatment, resulting in the accumulation of waste products. Intradialytic exercise improves the clearance of urea and creatinine by opening up vascular beds. Materials and methods We conducted a non-randomized interventional study to evaluate the effect of intradialytic aerobic exercise on dialysis parameters and fatigue among 295 hemodialysis patients selected through consecutive sampling (control group, n=147; experimental group, n=148) from two tertiary care centers. Baseline data on background variables and pre-test dialysis parameters (e.g., blood urea, creatinine, potassium, and hemoglobin levels) were assessed in both groups. Following connection to the hemodialysis machine, participants in the experimental group engaged in 15 minutes of intradialytic aerobic exercise per two hours of dialysis for a total of eight weeks, besides receiving routine care, compared to those in the control group. Post-test dialysis parameters were assessed for both groups at the end of the eighth week. The collected data were analyzed and tabulated using SPSS (IRB Inc., Armonk, New York). Results Intradialytic exercise led to significant improvements in post-test blood urea, creatinine, and fatigue in the experimental group (p<0.001). However, post-test serum potassium and hemoglobin levels remained relatively unchanged. Conclusion This study demonstrates the benefits of intra-dialytic aerobic exercise as a safe complementary therapy for a large population of dialysis patients, leading to better patient outcomes.

#828 Non-invasive determination of uric acid in blood during hemodialysis with an optical spent dialysate sensor

Abstract Background and Aims Kt/V urea is conventionally used hemodialysis (HD) adequacy marker, whereas many other uremic toxins with differing removal kinetics affect the mortality of end stage kidney disease (ESKD) patients. Among them, uric acid (UA) has been shown to cause cardiovascular mortality of ESKD patients. Recently, determination of UA concentration in blood with optical sensors during HD has been attempted by Lin et al in 2021 and Żyłka et al in 2023, but the accuracy has been relatively low. Moreover, Żyłka et al measured light absorption of spent dialysate at 573 nm to determine UA concentration, whereas previous research has shown that dialysate and UA have negligible light absorption in that region. The aim of this observational study was to predict concentration of UA with higher accuracy in ESKD patients’ blood during HD with various treatment settings by monitoring spent dialysate noninvasively with an optical sensor. Method Twenty-two ESKD patients on chronic HD were included into the study. Each patient received four 4 h long midweek HD sessions: one standard HD and three haemodiafiltration (HDF) sessions with different settings. Median (interquartile range) settings of the 1 HD session were: effective blood flow (Qb) = 199 (198-199) mL/min, dialysate flow (Qd) = 297 (297-298) mL/min, ultrafiltration rate (UF) = 13 (8-16) mL/min, dialyzer area 1.5 m2 and for the 3 HDF sessions: Qb = 298 (296-356) mL/min, Qd = 788 (489-792) mL/min, substitution fluid flow (Qsubs) = 96 (66-106) mL/min, UF = 11 (8-15) mL/min, dialyzer areas 1.8 m2 and 2.2 m2. Blood samples were collected before the start and at the end of each HD session from the arterial blood line and spent dialysate samples were collected 7, 60, 120, 180 and 240 min after the start from the outlet of the HD machine. Concentration of UA in spent dialysate and serum samples were determined with HPLC. An optical sensor (Optofluid Technologies OÜ, Tallinn, Estonia) was connected to the spent dialysate outlet of the HD machine and ultraviolet (UV) light absorption of spent dialysate was measured online in real time for each HD session. A linear interactions regression model was created using light absorbance at four different UV wavelengths to predict UA concentrations in collected spent dialysate samples. A curve of UA concentration for the whole HD session was determined based on the model and UV absorbance data measured with the optical sensor. Thereafter, UA concentration in spent dialysate at the start and at the end of each session (UAsensor hereinafter) was found from the concentration curve. The data of 88 HD sessions were equally divided into calibration and validation sets. Linear regression model was created using data of calibration set to predict concentration of UA (UApredicted) in blood as follows: UApredicted = a • UAsensor • $\frac{{{\rm{Qd}} + {\rm{\ Qsubs}} + {\rm{UF\ }}}}{{{\rm{Qb}}}}$, where “a” is the slope, UAsensor is the UA concentration in spent dialysate found from the concentration curve of the optical sensor, Qb is effective blood flow and Qd+Qsubs+UF is the total flow of spent dialysate. Subsequently, the accuracy of the model was evaluated on the calibration and validation data using Bland Altman analysis. Results UA concentrations in spent dialysate determined with HPLC and estimated with the optical sensor were strongly correlated (R2 = 0.992) and with comparable accuracy (BIAS±SE) (0.1 ± 3.84) µmol/L. Coefficient of determination 0.951 with the accuracy of 0.00 ± 31.43 µmol/L was achieved for calibration group, and coefficient of determination 0.962 with the accuracy of −7.64 ± 32.06 µmol/L was achieved for validation group between the UA concentration in blood determined with HPLC and corresponding values predicted by the optical sensor, respectively (Fig. 1). Conclusion Concentration of UA in dialysate and blood can be estimated noninvasively and accurately with the optical sensor in real time. This can be used to estimate removal efficiency and levels of UA during HD. In future, removal of other uremic toxins could be additionally monitored leading to a more personalized HD treatment.

The Effect of Engine Specifications, Technician Quality, and Bmhp Prices On Hospital Preferences In Nipro Hemodialysis KSO Contracts In Eastern Indonesia

The number of people with kidney failure in Indonesia currently reaches 1.6 million people with a prevalence of 6 per mile. The high number of people with kidney failure is caused by 2 main triggers, namely diabetes and hypertension. One form of treatment / treatment for patients with kidney failure is hemodialysis / dialysis using dialyzer services. Hemodialysis treatment can now be done in various health facilities services and is covered by BPJS financing. Hospitals as service providers collaborate with vendors / partners to procure machines and BMHP (Medical Consumables). The high demand for hemodialysis machines makes this industry/business create fierce competition. The form of competition between service provider vendors is in terms of machine specifications, after-sales service, and prices offered by each vendor. The form of cooperation between hospitals and vendors consists of various patterns / schemes. However, a common pattern used in cooperation between hospitals and vendors is in the form of Operational Cooperation (KSO) Consumable Purchases. This study raised the topic of opportunities for extending existing KSO contracts between hospitals and KSO partners, based on the influence of machine specifications, technician quality, and BMHP prices. This study will examine whether or not there is an influence of the three variables mentioned above on the hospital's decision to extend or terminate the KSO contract. The study data used the population of hemodialysis installations in the working area of Eastern Indonesia.

Hepatitis C Infection in Hemodialysis Patients, Makkah, Saudi Arabia

Hepatitis C virus (HCV) infection is the most common cause of chronic liver disease in the world and evaluation of the epidemiology of HCV infection was made possible by the development of a serological assay to detect antibodies to epitopes of HCV. Hemodialysis (HD) is considered to be one of the main risk factors of HCV transmission. The prevalence of antibodies to HCV (anti-HCV) in patients undergoing maintenance dialysis therapy (MDT) was found to be one of the highest among different risk groups and there is wide variation in the prevalence of HCV infection among different dialysis units and countries. Therefore, the prevalence of anti-HCV was studied in patients undergoing MDT. The current study is a cross section one, where a sample of 361 HD patients were selected randomly from HD centres in three governmental hospitals in Makkah city and they were subjected to assessment for the prevalence of anti-HCV by using questionnaires in addition to clinical measurements. The overall prevalence of anti-HCV among HD patients was 49.9% according to clinical measurements and questionnaires. The overall prevalence of anti-HCV among HD patients in Makkah city (49.9%) was comparable to that reported from other parts of the Kingdom of Saudi Arabia (KSA) and it is almost similar to the already reported positivity rate of (43.2%) from the eastern region of KSA and southern regions of KSA (45.5%). However, Strict adherence to universal precautions as recommended by the Centre for Diseases Control (CDC), meticulous regular disinfection of HD machines, Strict isolation of HCV-positive patients, dedicated dialysis machines and nursing staff at new dialysis set-up could possibly be the reasons of relatively low anti-HCV positivity at the current study than that reported by Shaheen et al., from four centres in the western region of KSA, (72.3%) and that by Huraib et al., in their multi-centre study in KSA, (68%) as well as the mean national rate. On the other hand, the use of more sensitive third generation enzyme - linked immunosorbent assay (ELISA) technique, long duration on HD, multiple blood transfusions, patients with dialysis treatment in multi-centres, factors related to infrastructure, environment and operational system might be responsible for the high prevalence of anti-HCV found in this study than that reported by Saeed et al., from Riyadh and those observed in the central region of KSA. Although routes of transmission are still unclear, early detection of all infected patients is mandatory for HCV prophylaxis in HD patients. Furthermore, an intensive educational program for staff members, HD patients and proper evaluation of the HD situation are needed. Thus, observation of appropriate preventive measures by all HD-centres is paramount.

Reliability of the hemodialysis machine through Weibull distribution in the presence of uncertainties

Reliability of the hemodialysis machine through Weibull distribution in the presence of uncertainties

Technical requirements and devices available for long-term hemodialysis in children-mind the gap!

Children requiring long-term kidney replacement therapy are a "rare disease" cohort. While the basic technical requirements for hemodialysis (HD) are similar in children and adults, key aspects of the child's cardiovascular anatomy and hemodynamic specifications must be considered. In this article, we describe the technical requirements for long-term HD therapy for children and the devices that are currently available around the world. We highlight the characteristics and major technical shortcomings of permanent central venous catheters, dialyzers, dialysis machines, and software available to clinicians who care for children. We show that currently available HD machines are not equipped with appropriately small circuits and sensitive control mechanisms to perform safe and effective HD in the youngest patients. Manufacturers limit their liability, and health regulatory agencies permit the use of devices, only in children according to the manufacturers' pre-specified weight limitations. Although registries show that 6-23% of children starting long-term HD weigh less than 15 kg, currently, there is only one long-term HD device that is cleared for use in children weighing 10 to 15 kg and none is available and labelled for use in children weighing less than 10 kg anywhere in the world. Thus, many children are being treated "off-label" and are subject to interventions delivered by medical devices that lack pediatric safety and efficacy data. Moreover, recent improvements in dialysis technology offered to adult patients are denied to most children. We, in turn, advocate for concerted action by pediatric nephrologists, industry, and health regulatory agencies to increase the development of dedicated HD machines and equipment for children.

Carbon-permeated magnetically actuated self-assembled cilia for heavy metal adsorption

Heavy metal contamination resulting from industrialization has become a pressing issue, prompting research on effective adsorbents for heavy metal adsorption and recovery. One promising approach involves incorporating magnetic particles into the adsorbent to enhance adsorption efficiency through magnetic manipulation. Moreover, among fluid-generating structures, magnetically actuated artificial cilia that can induce fluid flow through ciliary motion are notable examples. This paper proposes the first known study of magnetically actuated self-assembled artificial cilia (MSC), which generates fluid flow through magnetic actuation, with carbon permeation for heavy metal adsorption and desorption. We perform various experiments focusing on lead ion adsorption and desorption using the carbon-permeated MSC. Among carbon materials, MSC integrated with multiwalled carbon nanotubes (MWCNT) exhibits superior adsorption performance and capacity. The lead-ion adsorption performance of MWCNT-permeated MSC (M-MSC) is evaluated under varying environmental conditions, showing an increase in adsorption capacity of 11 times and a higher adsorption rate constant when actuated. The reusability of M-MSC is confirmed through repeated experiments, and an in situ channel experiment is implemented. In the future, the proposed carbon-permeated MSC is expected to be applied to remove heavy metal contaminants from fluid systems and specialized medical devices like hemodialysis machines.

Development of Dialysis and Leakage Detection on Different Technology

Dialysis is the treatment for chronic kidney disease (CKD) patients, including acute or end-stage renal disease (ESRD), by performing the filtration of toxic or waste substances from the patient’s body. Haemodialysis (HD) and peritoneal dialysis (PD) are common treatments for dialysis patients with the use of extracorporeal dialysis machines such as haemodialysis machines or automated peritoneal dialysis (APD) for HD and PD, respectively. For HD, is required a dialyser act as a single-use consumable during the treatment of the patient. However, the major concern on the haemodialysis machine might be the issue on false sense during the treatment. The leakage detector of the dialysis machine is important to detect and sense the parameters when that is a leakage event, such as blood leakage at the dialyser or arteriovenous fistula (AVF) dysfunction. Thus, this study provides a review of leakage detection that has been developed with different methodologies of the sensing unit on a haemodialysis machine.

Efficiency of a Fully Integrated Hemodialysis (HD) Machine in the Acute Care Setting

Efficiency of a Fully Integrated Hemodialysis (HD) Machine in the Acute Care Setting

Fifty years of hemodialysis in Ghana—current status, utilization and cost of dialysis services

BackgroundKidney failure is common in Ghana. Haemodialysis (HD) is the most common treatment modality for survival. Although, HD has been available in Ghana for 50 years, the majority of patients who develop kidney failure cannot access it. We describe the state of HD, dialysis prevalence, its utilization and cost of HD after fifty years of dialysis initiation in Ghana.MethodsA situational assessment of HDs centres in Ghana was conducted by surveying nephrologists, doctors, nurses and other health care professionals in HD centres from August to October 2022. We assessed the density of HD centres, number of HD machines, prevalence of nephrologists, number of patients receiving HD treatment and the cost of dialysis in private and government facilities in Ghana.ResultsThere are 51 HD centres located in 9 of the 16 regions of Ghana. Of these, only 40 centres are functioning, as 11 had shut down or are yet to operate. Of the functioning centres most (n = 26, 65%) are in the Greater Accra region serving 17.7% of the population and 7(17.5%) in the Ashanti region serving 17.5% of the population in Ghana. The rest of the seven regions have one centre each. The private sector has twice as many HD centers (n = 27, 67.5%) as the public sector (n = 13,32.5%). There are 299 HD machines yielding 9.7 HD machines per million population (pmp) with a median of 6 (IQR 4–10) machines per centre. Ghana has 0.44 nephrologists pmp. Currently, 1195 patients receive HD, giving a prevalence of 38.8 patients pmp with 609(50.9%) in the private sector. The mean cost of HD session is US $53.9 ± 8.8 in Ghana.ConclusionThere are gross inequities in the regional distribution of HD centres in Ghana, with a low HD prevalence and nephrology workforce despite a high burden of CKD. The cost of haemodialysis remains prohibitive and mainly paid out-of-pocket limiting its utilization.

Pengaruh Benson Terhadap Nyeri Insersi pada Pasien yang Menjalani Hemodialisa di RSUD Kota Tanjungpinang

Insertion pain is pain caused by the action of inserting a needle into the AV fistula as a link between blood vessel circulation and the hemodialysis machine during the hemodialysis process. In Brazil it was found that 70% of patients undergoing hemodialysis experienced mild to moderate pain at the time of AV fistula insertion. The phenomenon found in the hemodialysis unit at Tanjungpinang City Regional Hospital in 2020 was 33 patients experiencing moderate pain. This research was conducted to determine the effect of the Benson relaxation technique on pain during insertion in patients undergoing hemodialysis. The research method is a quasi experimental design, with a pre test – post test design approach without control group. The sample consisted of 30 respondents in the intervention and control groups who were routine hemodialysis patients at the Tanjungpinang City Regional Hospital in 2023. Using a non-probability sampling technique, consecutive sampling. Data were processed using the Wilcoxon signed rank test. Univariate analysis of results before the Benson technique, 73.3% experienced moderate pain and after the Benson technique, 80% did not feel pain in the intervention group. It was concluded that there was an influence of the Benson technique on insertion pain in patients undergoing hemodialysis. It is hoped that the Benson relaxation technique will be applied by nurses as non-pharmacological pain management to reduce AV-fistula insertion pain in hemodialysis patients.