The thermal hydraulic characteristics and heat transfer of two-phase fluid in helical coil once-through steam generator under ocean conditions like rolling and heaving motions are studied numerically. A CFD model is established to analyze the effects of motion parameters like amplitude, period and rolling radius and the heat flux distribution are discussed. The analysis shows that the overall heat transfer decreases under ocean conditions, but the overall deterioration is limited, indicting the helical coil pipe has the stability for ocean conditions. The additional forces like Coriolis, centrifugal and inertial forces introduced by rolling motion are analyzed theoretically and the result shows it detorts the original two main vortexes responsible for high heat transfer due to its spiral geometry, making heat transfer fluctuates up and down periodically near the steady state value. As rolling height increases, the heat transfer is nonlinear due to the competition between Coriolis force and centrifugal and inertial forces. As rolling amplitude increases, the heat transfer variation increases and the local heat transfer deterioration is severely aggravated, indicating high rolling amplitude should be avoided as possible. Increasing rolling period makes heat transfer behavior more approximate to static case as gravity and centrifugal force due to spiral geometry is dominate. Under heaving motion, the overall heat transfer decreases, and increasing heaving amplitude and decreasing period make the fluctuation more severe.