This study aims to develop an integrated design strategy for an office building in Tehran, optimizing energy efficiency and minimizing virus infection risk, addressing global challenges such as energy conservation and virus transmission. A multi-objective optimization model is developed to identify optimal design parameters for energy performance and infection risk reduction. Environmentally sustainable materials and energy-efficient equipment, such as solar panels, high-efficiency heat pump systems, and advanced air filtration techniques, are employed. The modified Wells-Riley Risk Model calculates infection risk, while energy efficiency is formulated based on the technologies used. Results showcase a significant 14% increase in energy efficiency and a 46% decrease in infection risk compared to traditional building designs, demonstrating the effectiveness of the proposed integrated approach. The optimal design parameters include ventilation rate, the number of solar panels, hot water pipe diameter, and heat pump condenser temperature. This study presents a practical, sustainable solution for designing office buildings that actively address pressing global concerns while fostering healthier, energy-efficient environments. The novelty of this research lies in the development of a multi-objective optimization model that synergizes infection control and energy efficiency, accounting for real equipment parameters and providing a new paradigm for HVAC design. This integrated strategy optimizes decision variables like ventilation rate, filtration level, solar panels, and heat pump operating conditions, offering a comprehensive approach to co-optimize infection control and energy performance.
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