Heart disease is a critical issue that affects people, causes serious sickness, and is the main cause of mortality worldwide. Early diagnosis of disease plays a significant role in heart disease prediction and is attained by various automation techniques. The availability of automation techniques initiates the necessity for medical data and the storage of medical data becomes a research problem due to its high sensitivity. The emergence of IoT networks formed a promising solution for data storage through the cloud server and preventing the data from various threats is a challenging problem. A secure heart disease prediction system is developed by the utility of the ESVO-based Swish Bessel CNN classifier (Emperor Spheniscidae Vampire Optimization-based Swish Bessel Convolutional Neural Network), and the important significance of the research depends on the ESVO optimization that helps in gaining a deeper insight of the classifier as well as helps in preventing the threatening of data. The security of the cloud server is enhanced by the EDH-ECC (Entropy Diffie Hellman – Elliptic Curve Cryptography) which promotes the information exchange even in unsecured channels. Similarly, the authentication and authorization of the cloud server are carried out using the EAN-13 and salt-based digital signature that initiates strong credentials and enhance data security. Finally, the heart disease is diagnosed using the ESVO-based Swish Bessel CNN classifier. Assessing the accuracy, sensitivity, specificity, and F1-measure, which provided values of 94.877 %, 95.464 %, 93.293 %, and 95.14 % shows the effectiveness of the research.
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