Healthy Levels Of Physical Activity Research Articles

The Impact of the COVID-19 Pandemic on Physical Activity and Quality of Life Among Ukrainian Students

The COVID-19 pandemic continues to pose serious challenges to society. Strategies such as social distancing are employed to reduce its spread; however, this can lead to a sedentary lifestyle. Many people report difficulties in maintaining a healthy level of physical activity during the pandemic. The aim of this study was to examine the levels of physical activity and quality of life among Ukrainian university students during the COVID-19 pandemic. A diagnostic questionnaire was used, and the International Physical Activity Questionnaires (IPAQ) were employed to assess participants' physical activity levels. The study involved 662 students from three Ukrainian universities. A significant decrease in physical activity and an increase in sleep duration were observed during the COVID-19 pandemic. One of the main advantages of this study was the use of both cross-sectional and longitudinal analyses. The study also allowed for the evaluation of two types of behavior: physical activity and sleep. The conclusions. After the onset of the COVID-19 pandemic, physical activity was low in 90% of students, amounting to 791±7.3 MET, with a significant amount of time (8.6±1.2 hours) spent on sleep, while less than half of the participants (40.2%) met the recommended physical activity guidelines.

Exploring 24-Hour Movement Behaviors in Early Years: Findings From the SUNRISE Pilot Study in Tunisia.

The International Study of Movement Behaviors in the Early Years(SUNRISE) was conducted in Tunisia to assess the proportion of preschoolers who met the World Health Organization guidelines for physical activity, sedentary behavior, and sleep. The study also evaluated the feasibility of the methods for the SUNRISE study. Five kindergartens were recruited from urban and rural areas in Tunisia. Physical activity and sleep duration were assessed using a waist-worn ActiGraph. Screen time and sleep quality were assessed via an interview-administered parent questionnaire. The NIH Toolbox was used. A total of 112 preschoolers were assessed (50 boys, age = 4.1 [0.58]). Only 18% of children met all recommendations of the World Health Organization guidelines, while 53% met the sedentary screen time (in minutes per day), and 41% met physical activity recommendation (in minutes per day). Eighty-one percent of children met the sleep duration recommendation (in minutes per day). There was good compliance with the ActiGraph protocol. This pilot study provided important insights into the feasibility of the study and the movement behaviors of Tunisian preschool children. The results suggest there is a need to promote healthy levels of physical activity and sedentary screen time in children, which should be a priority in public health initiatives, including preschool curricula, in Tunisia.

Are gastrointestinal signals the principal guides to human appetite and energy balance?

In view of the exponential rise of global obesity in the past three quarters of the century, it is useful to examine what is driving this change and what approaches can curb it. The chief drivers of weight gain are, on one hand our misunderstanding of the mechanisms controlling energy balance, and, on the other, reliance on current, potentially misleading conflicting scientific opinions and government policies regarding the controls of human appetite. This review outlines the evidence that: (1) there is no direct bioenergetic feedback from energy metabolism or energy stores to the brain mechanisms guiding feeding and energy expenditure, (2) human appetite is controlled by signals originating from an empty or full stomach, food palatability and opportunities to eat as well by the rate of food absorption, that (3) humans bear a genetic burden of having high ability and capacity to store fat and mechanisms that curb body- mass and fat loss, (4) humans are motivated to overconsume while maintaining low energy expenditure, and (5) commercial interests of food businesses marketing highly palatable foods, and wide-spread mechanization of living tasks and urban design reduce the need for physical work and movement. The non-pharmacological and non-surgical solutions to obesity involve an understanding of human genetic impediments and environmental obstacles to maintaining healthy weight, coupled with deliberate corrective or preventive behaviors, such as understanding and using gastrointestinal tract signals that provide sufficient, albeit subtle, cues for sensible food intake, and using daily weight monitoring and activity tracking devices to record and motivate healthy levels of physical activity.

The use of sports facilities for physical activity: a public health and equity perspective

Background: despite multimillion-dollar investments in sports facilities, there is little information on their contribution to energy expenditure of the population. In this study, participation in 71 physical activities (PAs) and 31 different types of spaces was examined. Objectives: to evaluate which types of spaces are more effective from a public health perspective. Methods: a cross-sectional sample was designed, stratified and proportional to the adult population of Gran Canaria (n = 3,000, ≥ 18 years). PA was evaluated using a validated questionnaire. The spaces used were grouped into two categories: public open spaces and sport facilities. Descriptive statistics and multiple logistic regression were used to analyze the data. Results: the open public spaces accumulated a volume of hours for PA between 1.6 and 28.4 times higher than the sport facilities depending on the socio-demographic group analyzed. The indoor sport facilities were the ones that expressed the greatest associative strength with the achievement of PA recommendations (OR = 5.45, 95 % CI: 4.01; 7.40). Conclusion: a dilemma was posed from a public health perspective because the urban open public spaces reached more population and supported most of the population's energy expenditure, particularly in the groups with the highest health risk, but the indoor sport facilities were the ones that best contributed to achieving a healthy level of physical activity. This study suggests changes in the polices of construction and management of sport facilities and open public spaces to increase PA in groups at higher health risk.

HOW DO NUTRITIONAL STATUS AND EXERCISE AFFECT DYSMENORRHEA IN JUNIOR HIGH SCHOOL STUDENTS

Children in junior high school benefit significantly from participating in various sports, particularly those geared toward female students. Many people achieve a healthy level of physical activity, which is affected by multiple factors, including nutritional status and those connected to dietary factors. Because the body relies on certain foods as sources of energy, the construction of body cells, the production of biocatalysts, and the metabolism of food are all required to follow the body. This study focused on the experiences of female students at SMP Kepulauan Meranti Regency when they were engaged in the process of acquiring sports-related knowledge. Through the use of the correlational research approach, this study aims to establish whether there is a connection between two or more variables. According to the findings, it was determined that the level of physical activity engaged by some of the female students at this institution is still inadequate or not very excellent. This can be seen mainly from their appearance and attitude, particularly in following and doing the learning materials of the health assessor, where it seems that female students are lazy in doing sports activities, get tired quickly, and lack enthusiasm. Some of them have pale faces, indicating that they are unhealthy.

Effectiveness of activity-monitoring devices in patients with cardiovascular disease participating in cardiac rehabilitation programs: an umbrella review protocol.

The objective of the review is to investigate the effect of activity-monitoring devices and mobile applications on physical activity and health outcomes of patients with cardiovascular disease who are participating in cardiac rehabilitation programs. Supporting patients with cardiovascular conditions to achieve and maintain healthy physical activity levels is the cornerstone of cardiac rehabilitation programs. The effectiveness of activity-monitoring devices and mobile applications (such as physical activity interventions) utilizing consumer-grade monitoring devices and applications to support patients to improve exercise levels during and after program completion has been investigated. Several systematic reviews evaluating the effectiveness of monitoring devices and applications have indicated varying clinical impact, depending on patient characteristics, stage of rehabilitation, and type of intervention. This review will consider systematic reviews and/or meta-analyses of randomized controlled trials of patients who participated in cardiac rehabilitation programs that included a physical activity intervention that incorporated activity monitoring using electronic devices and/or mobile applications and reported activity and patient health outcomes. MEDLINE, Embase, Sport Discus, the Cochrane Database of Systematic Reviews, Scopus, CINAHL, the International Network of Agencies for Health Technology Assessment database, Epistemonikos, and Web of Science will be searched from inception to the present. PROSPERO will be searched for unpublished reviews. Articles will be screened by two independent reviewers for inclusion, and methodological quality will be assessed using a JBI critical appraisal tool. Data will be extracted from systematic reviews and a data synthesis of findings will be presented. The certainty will be assessed using the Grading of Recommendations Assessment, Development and Evaluation approach. PROSPERO CRD42022298877.

S02-4 Physical activity and screen time during the COVID-19 lockdown in Europe: repeated cross-sectional study in 10 countries

BackgroundTo date, few multi-country data on how the COVID-19 pandemic and restrictions affected children’s physical activity have been published, and most reports originate outside Europe. This repeated cross-sectional study investigated the prevalence and correlates of physical activity (PA) and screen time (ST) in a large sample of European children during the COVID-19 pandemic in January-February 2021, and compared the data to the first lockdown in May-June 2020.MethodsData from two online survey rounds were analysed. A total of 8,395 children aged 6-18 years were included in Round 1 (May-June 2020) and 24,302 in Round 2 (Jan-Feb 2021). PA and ST were assessed by 7-day recall measure.ResultsOverall, 9.3% of children (95%CI, 6.9-11.7) met the WHO PA recommendation, which is half of what was observed in Spring 2020 (19.0% [18.2-19.9]). Exceeding ST recommendations was also prevalent in both data collection rounds. Playing outdoors more than 2 hours/day, following a daily routine and being active in online P.E. increased the odds of healthy levels of physical activity and screen time. We also observed a large variability in curriculum time allocated for P.E. In many countries this was lower than the compulsory requirements.ConclusionsFindings suggest that lockdown in winter has greater negative impact than in spring. Promoting safe and responsible outdoor activities, safeguarding P.E. lessons during distance learning and setting pre-planned, consistent daily routines are important in helping children maintain healthy active lifestyle in pandemic situation. These factors should be prioritised by policymakers, schools and parents.

24-Hour movement behaviours and COVID-19 among children in the Kingdom of Saudi Arabia: A repeat cross-sectional study

This study investigated how children's 24-hour (24-h) movement behaviours were affected by SARS-CoV-2 (COVID-19) in the Kingdom of Saudi Arabia. Previous research examined 24-h movement behaviours in Saudi Arabia seven months after the World Health Organization (WHO) declared COVID-19 a global pandemic. This repeat cross-sectional study examined changes in 24-h movement behaviours 12 months after the WHO declaration. The Time 2 survey repeated five months (1 March – 15 May 2021) after Time 1 survey (1 October – 11 November 2020). The survey was distributed to parents of children aged 6–12 years across Saudi Arabia via an online survey. Children were classified as meeting 24-h movement guidelines if they reported uninterrupted sleep for 9–11 ​h per night, ≤ 2 ​h of recreational sedentary screen time (RST) per day and ≥ 60 ​min of moderate-to vigorous-intensity physical activity (MVPA) per day. A total of 1 045 parents from all regions of Saudi Arabia responded (42.4%). Only 1.8% of children met all components of the guidelines, compared to 3.4% in Time 1. In the present study, girls spent more days per week in MVPA ≥ 60 ​min duration than boys (3.0 vs 2.6; p ​= ​0.025), while boys had spent more days per week engaged in activities that strengthened muscle and bone than girls (3.0 vs 2.8; p ​= ​0.019). Healthy levels of physical activity (PA), sedentary behaviour (SB) and sleep further declined in Saudi children five months after the Time 1 survey. These challenges require urgent intervention to ensure children's movement behaviours improve as Saudi Arabia moves out of the COVID-19 pandemic.

Patterns of Physical Activity Among University Students and Their Perceptions About the Curricular Content Concerned With Health: Cross-sectional Study.

University students are at risk of losing their focus on maintaining healthy levels of physical activity because of their engagements with curricular and cocurricular activities. In India, the physical activity levels of the adult population have been reported to be declining in the recent years. However, studies focusing on university students pertaining to their physical activity are lacking in the Indian context. Moreover, a question that has not been properly addressed is the following: "do the curricula in higher education promote physical activity?" Our paper aims at describing the physical activity levels of the students in a large public-funded central university located in northern India. The study also aims at capturing the student perceptions about the emphasis they receive on leading a physically active lifestyle during their routine curricular activities. This is a cross-sectional descriptive study and uses International Physical Activity Questionnaire-Long Form to record physical activity among 4586 students. Stratified sampling method was used to enroll the students from each stream (faculty). Out of 30,667 students, about 15% were included from each faculty. The study was conducted between 2016 and 2019. To capture the student perceptions, we used a newly developed 5-item scale. From a total of 4586 participants in the study, 2828 (61.7%) were male and 1758 (38.3%) were female students. The mean age of our sample was 22.34 (SD 3.12) years. Our results indicate that about 14.5% (n=666) of all students in the study fall under the "Inactive" category. Furthermore, the perception about the curricular content pertaining to physical activity varied widely between the students of different streams. Our sample reported a better physical activity pattern in comparison to the reported overall physical activity levels of the adult population of India. Our results also suggest that health-related topics are inadequately represented in many of the streams of higher education in the university.

Cross-sectional study of physical activity among long-term melanoma survivors and population controls.

Physical activity has been associated with improved outcomes among cancer survivors of various malignancies; however, this topic is understudied among melanoma survivors. Our objective was to determine whether long-term melanoma survivors are less likely to meet American Cancer Society physical activity guidelines than non-melanoma population controls. We conducted a cross-sectional survey in 2015 to follow up participants from a case-control study of melanoma and population controls in Minnesota. The primary outcome was meeting American Cancer Society recommendations for healthy physical activity levels. Physical activity, sun protection practices and time spent outside were compared between survivors and controls using generalized linear regression models. Melanoma survivors (N = 724) and controls (N = 639) were similar with the exceptions of daily hours spent outside, sun protection scores, skin tone, and smoking status. Half (50.8%) of melanoma survivors reported meeting the physical activity guidelines, compared to 39.7% of controls (p < 0.0001), with an 11% (95% CI 0.05-0.17) difference after adjusting for potential confounders. While long-term melanoma survivors were more likely to meet American Cancer Society physical activity guidelines than population controls, nearly 50% did not meet recommendations. This finding is concerning given the known improvements in quality of life and survival among physically active cancer survivors. Opportunities remain to promote physical activity among melanoma survivors. Health communications that promote outdoor exercise, in particular, should include advice about sun protection.

Treatment resistant depression (TRD) service outpatient’s experience of sleep, activity, and using a Fitbit wearable activity and sleep tracker

PurposeDepression, physical health, well-being, sleep and physical activity are interlinked. Healthy levels of physical activity and effective night-time sleep can reduce depressive symptoms. In the context of their lives and symptoms of depression, this paper aims to understand participants’ experiences of using a Fitbit, physical activity and sleep and the barriers and facilitators for healthy sleep and physical activity.Design/methodology/approachQualitative methods were used to conduct interviews with 19 patients (4 male; 15 female) diagnosed with treatment-resistant depression undergoing transcranial magnetic stimulation (TMS) treatment for depression. Reflexive thematic analysis was used.FindingsHealthy sleep and physical activity levels are interlinked and reduce depressive symptoms as well as improving well-being and physical health. A Fitbit is useful to enhance physical activity, self-awareness, motivation, healthier lifestyles and effective sleep. Barriers to healthy sleep and physical activity levels included depressive symptoms, environmental factors and anxieties. Facilitators for healthy sleep and physical activity levels included knowledge of the benefits, support from family and friends and applying sleep hygiene.Practical implicationsThere is a need to provide interventions using wearable activity trackers that build on the links between increased physical activity, improved sleep, enhanced well-being, better physical health and lower depressive symptoms.Originality/valueTo the best of the authors’ knowledge, this is the first time that patients undergoing TMS have had their experiences of sleep, activity and using a Fitbit investigated and reported.

Step It Up: Increasing Physical Activity for Adults With Autism Spectrum Disorder and Intellectual Disability Using Supported Self-Management and Fitbit Technology

Adults with autism spectrum disorder and intellectual disability often do not engage in healthy levels of physical activity despite its many benefits. We conducted a randomized control trial to evaluate the effectiveness and feasibility of the Step It Up program, which used supported self-management strategies, on daily step counts, health measures, and perceived quality of life for adults with autism spectrum disorder and intellectual disability. Forty participants, ages 18 to 57, were randomly assigned to a control or intervention group. Males accounted for 70.6% of participant gender. Both groups received Fitbits and Fitbit training, and they participated in pre- and post-assessments. The intervention group participated in the Step It Up program. Participants in the intervention group had significantly higher step counts and lost more weight. Feasibility and acceptability were also high. This study provides valuable data on using a supported self-managed exercise program as well as insight into its feasibility in home settings.

Coping with the COVID-19 pandemic: the role of physical activity. An international position statement

Since its appearance at the end of 2019 and the beginning of 2020 in Wuhan (China), the coronavirus disease 2019 (COVID-19) has spread rapidly worldwide. The outbreak was declared a pandemic in March 2020. Home confinement, travel restrictions, the closing of venues for exercise and recreation, and the cancellation of indoor and outdoor events including sport have been characteristic features of the public health responses around the world. The result has been a reduction in the levels of physical activity experienced by large numbers of the world population of all ages. This has caused considerable alarm for physical activity professionals around the world. In response, this position statement makes a case for the importance of continuing to embrace regular physical activity alongside the existing public health strategies that are being implemented in the management of the effects of the virus internationally. To be consistent with these policies this activity should always be away from others (application of social distancing) and preferably outdoors. Some potential benefits specific to the current situation, are suggested by reference to existing knowledge about the significance of exercise in the maintenance of a healthy immune system. However, these recommendations need to be viewed primarily within an unchanging context of the long-term value of healthy levels of physical activity for population well-being and quality of life. This has been made the more important on account of the potential harmful effects of the current reduced levels. Some recommendations for appropriate dosage and types of PA for those with different conditions are provided.

Physical activity, screen time and the COVID-19 school closures in Europe – An observational study in 10 countries

ABSTRACT To date, few data on how the COVID-19 pandemic and restrictions affected children’s physical activity in Europe have been published. This study examined the prevalence and correlates of physical activity and screen time from a large sample of European children during the COVID-19 pandemic to inform strategies and provide adequate mitigation measures. An online survey was conducted using convenience sampling from 15 May to 22 June, 2020. Parents were eligible if they resided in one of the survey countries and their children aged 6–18 years. 8395 children were included (median age [IQR], 13 [10–15] years; 47% boys; 57.6% urban residents; 15.5% in self-isolation). Approximately two-thirds followed structured routines (66.4% [95%CI, 65.4–67.4]), and more than half were active during online P.E. (56.6% [95%CI, 55.5–57.6]). 19.0% (95%CI, 18.2–19.9) met the WHO Global physical activity recommendation. Total screen time in excess of 2 h/day was highly prevalent (weekdays: 69.5% [95%CI, 68.5–70.5]; weekend: 63.8% [95%CI, 62.7–64.8]). Playing outdoors more than 2 h/day, following a daily routine and being active in online P.E. increased the odds of healthy levels of physical activity and screen time, particularly in mildly affected countries. In severely affected countries, online P.E. contributed most to meet screen time recommendation, whereas outdoor play was most important for adequate physical activity. Promoting safe and responsible outdoor activities, safeguarding P.E. lessons during distance learning and setting pre-planned, consistent daily routines are important in helping children maintain healthy active lifestyle in pandemic situation. These factors should be prioritised by policymakers, schools and parents. Highlights To our knowledge, our data provide the first multi-national estimates on physical activity and total screen time in European children roughly two months after COVID-19 was declared a global pandemic. Only 1 in 5 children met the WHO Global physical activity recommendations. Under pandemic conditions, parents should set pre-planned, consistent daily routines and integrate at least 2-hours outdoor activities into the daily schedule, preferable on each day. Schools should make P.E. lessons a priority. Decision makers should mandate online P.E. be delivered by schools during distance learning. Closing outdoor facilities for PA should be considered only as the last resort during lockdowns.

“I sit all of the time”: Health-related time-use among adults with intellectual disabilities

BackgroundAdults diagnosed with intellectual disabilities (ID) are more likely to have cardiometabolic risk factors, including low physical activity (PA), high sedentary behavior (SB), and poor sleep. While these behaviors have typically been studied in isolation, emerging frameworks propose a more integrated approach to the study of these behaviors, asserting that the relative proportion of time spent in each of the health-related time-use behaviors (i.e. PA, SB and sleep) across the 24 -h period is a more powerful determinant of the incidence and progression of disease. This approach has yet to be considered for adults with ID. The purpose of this study was to explore how adults with ID and their formal caregivers (i.e. employed caregivers) perceived their health-related time-use, including the factors that influence their time-use. MethodFive focus groups were conducted with twelve adults with ID and ten formal-caregivers. Consistent with an interpretive paradigm, this study employed an interpretative phenomenological analysis (IPA) methodology. ResultsThree interrelated themes were identified: (1) Caregivers as gatekeepers to healthy time-use; (2) Places to move; and (3) Daily movement. The themes captured the participants’ perspectives of interpersonal and environmental factors that influence health-related time-use, and how these factors were common to engagement in at least on health-related time-use behavior. ConclusionsInterpersonal factors, including caregivers support and modeling-behaviors, and community factors, in the form of local, accessible, affordable spaces to be active, were identified as the most pertinent factors in determining PA, SB and sleep behaviors. Moreover, adults with ID and caregivers perceived health-related time-use behaviors to be interrelated. Further investigation in this area will ultimately inform the development of pilot interventions that support caregivers as gatekeepers and provide access to health-promoting environments to engage adults with ID in healthy levels of PA, SB, and sleep.

Benefits and promotion of physical activity in rheumatoid arthritis.

The aim of this article is to describe the benefits of physical activity and exercise on rheumatoid arthritis disease activity, functioning, and symptoms; and offer recommendations for promotion of physical activity and exercise among people with rheumatoid arthritis. In addition to well-known benefits of exercise such as improving cardiovascular health and metabolic syndrome and reducing obesity, exercise has consistently shown rheumatoid arthritis-specific benefits. Exercise and increases in physical activity improve clinically measured disease activity, reduce symptoms such as fatigue and pain, and improve function and mental health. In spite of these benefits, most people with rheumatoid arthritis are inactive. Patient barriers to engaging in physical activity may include fears of joint damage, rheumatoid arthritis symptoms, and lack of understanding that physical activity improves the symptoms that may be barriers. However, the greatest barrier to healthy levels of physical activity among individuals with rheumatoid arthritis appears to be the lack of direction from healthcare providers. Exercise is safe and highly beneficial for people with rheumatoid arthritis. Because receiving recommendations from healthcare providers may be the factor most strongly associated with engaging in physical activity or exercise, providers are encouraged to give patients positive messages about the benefits of physical activity and the extremely low risks of harm.

Mexico's 2018 Report Card on Physical Activity for Children and Youth: Full report.

ABSTRACTObjectives.Mexico’s 2018 Report Card evaluates the opportunities available for Mexican children and youth to reach healthy levels of physical activity, sleep, and sedentary behavior.Methods.The Report Card is a surveillance system that gathers data from national surveys, censuses, government documents, websites, grey literature, and published studies to evaluate 16 indicators in four categories: Daily Behaviors; Physical Fitness; Settings and Sources of Influence; and Strategies and Investments. Data were compared to established benchmarks. Each indicator was assigned a grade from 1 – 10 (< 6 is a failing grade) or “incomplete” if data was insufficient/unavailable.Results.Daily Behavior grades were: Overall Physical Activity, 4; Organized Sport Participation, 5; Active Play, 3; Active Transportation, 5; Sleep, 7; and Sedentary Behavior, 3. Physical Fitness, received a 7. Settings and Sources of Influence grades were: Family and Peers, incomplete; School, 3; and Community and Environment, 4. Strategies and Investments were: Government Strategies, 6; and Non-Government Organizations, 2.Conclusion.Low grades in 11 of the 16 indicators indicate that schools, families, communities, and government need to work together to improve physical activity opportunities for children and youth in Mexico.

The Effect of Physical Activity on Academic Performance and Mental Health: Systematic Review

Examining the association between participation in physical activities and academic achievement is important for many reasons. Understanding the relationship between participation in sport activities, academic achievement and cognitive development is very important for teachers, school psychologists and other stakeholders. The relationship among physical activity, academic achievement and mental health has long been theorized to be of profound importance in understanding human behavior and development. This review article aims specifically to highlight the state of existing research pertaining to the relationship between physical activity and the state of mental health. Different studies, summarized here, have found that healthy levels of physical activity generally correlate with mental health and academic achievement. This review result has showed that there was a significant relationship between physical fitness level and academic achievement and higher academic achievement was associated with higher levels of physical fitness. Increased physical activity levels and fitness can improve bone and musculoskeletal function and help alleviate or relieve depression, anxiety and stress. Generally, the previous research findings from large-scale observational studies indicate that participation in physical activity has a small to moderate effect in prevention and management of the risk of depression and anxiety which in turn have effect on academic achievement and mental health. Physical activity is a relatively cheap and non-harmful lifestyle intervention that can easily be implemented into school settings.

Walking the boundaries: using the 6-min walk test for accurate assessment of the level of fitness in breast clinic outpatients.

Healthy levels of physical activity and improved fitness have shown better quality of life outcomes and improved survival in women with breast cancer. There is a lack of baseline data for fitness levels in breast cancer outpatients in Australia. A single centre cross-sectional study was performed to provide a snapshot of the fitness levels of women attending the Surgical and Oncology Breast Outpatient Clinic at Western Health, Melbourne. A total of 200 women (aged 18-85 years) were surveyed and the 6-min walk test (6MWT) was performed. Single and multiple linear regression analyses were performed. The mean 6-min walk distance (6MWD) was 486.6 m (95% CI ±12.8 m), which was comparable with reference ranges. The mean age of participants was 47.5 years. Ninety-seven (48.5%) participants had diagnosis of breast cancer. Breast cancer diagnosis had a negative effect on 6MWD of -33.6 m walked (P = 0.010). However, multiple regression analysis showed that only age (-2.6 m walked per year older; P < 0.001), body mass index (-4.2 m walked per unit of body mass index increase; P < 0.001) and presence of comorbidities (-56.9 m walked; P < 0.001) had statistically significant negative effects on 6MWD. Self-reported exercise tolerance correlated significantly with 6MWD (walking: P < 0.001 and stairs: P = 0.014). The 6MWT was easily performed within outpatient environment to accurately assess baseline level of fitness in breast cancer clinic outpatients. This indicates that 6MWT can be used as a valuable adjunctive tool to assess the level of fitness in breast cancer patients to make therapeutic recommendations in improving breast cancer outcomes.

SEX DIFFERENCES IN QUADRICEPS STRENGTH AMONG ADOLESCENTS WITHIN 1 YEAR OF ACL RECONSTRUCTION

Background Female patients with ACLR are 40% less likely to return to preinjury levels of sport after subsequent ACLR when compared to their male counterparts. Additionally, 24-30% of young female athletes who do return to sport will go on to experience a second ACL injury to the ipsilateral or contralateral knee within 2 years of ACLR. Despite these findings, sex-based differences in clinical outcomes following ACLR are not currently well understood within the adolescent population. Involved limb knee extension weakness, contralateral limb knee extension weakness, and between limb strength asymmetry persist months to years following ACLR among adolescent patients. Improvements in unilateral and symmetry-based measures of knee extension strength during and after the rehabilitation process have been linked to improved patient-reported knee related function, lower extremity functional performance, and decreased risk of subsequent ACL injury among individuals with recent ACLR. Currently, there is a lack of evidence describing the role that sex plays in persistent quadriceps weakness. Therefore, the purpose of this study was to investigate the effects of patient sex on unilateral and symmetry-based measures of knee extension strength, and patient-reported knee function among adolescent individuals with ACL reconstruction (ACLR) within the first year after surgery. Methods: Fifty-two male participants (age = 16.8±1.3 years, BMI = 25.6±5.6 kg/m2, time since surgery = 6.3±1.4 months) and 66 female participants (age = 16.7±1.4 years, BMI = 23.9±3.9kg/m2, time since surgery = 6.8±1.7 months) with unilateral ACLR, 4-12 months prior to enrollment were recruited for this multi-site cross-sectional study. Participants completed bilateral knee extension maximal voluntary isometric contraction (MVIC) torque assessments using a multimodal dynamometer with continuous verbal encouragement from the tester and visual feedback on a nearby monitor. Peak knee extension MVIC torque was identified for each of 3 trials and was normalized to body mass (Nm/kg). Limb symmetry indices were also calculated by dividing the MVIC torque obtained for the involved limb by the MVIC torque obtained for the contralateral limb. Participants also completed the International Knee Documentation Committee (IKDC) Subjective Knee Form to assess patient-reported knee function. Sex-based comparisons of quadriceps strength outcomes and IKDC score were made using separate ANCOVAs where time since surgery was utilized as a covariate. Cohen’s d effect sizes and 95% confidence intervals (CI95) were calculated to assess the magnitude of sex difference for all outcome measures. Odds ratios and CI95 were also calculated to assess the odds of an adolescent female achieving clinical threshold for acceptable involved limb quadriceps strength (MVIC = 3.0 Nm/kg), quadriceps limb symmetry (LSI = 90.0%), and patient-reported knee function (IKDC = 90.0). Results: The involved limb (male = 2.08±0.95 Nm/kg, female = 1.69±0.63 Nm/kg, p = 0.01, d = -0.50, CI95 = -0.13 to -0.87) and contralateral limbs (male = 2.75±0.75 Nm/kg, female = 2.31±0.64 Nm/kg, p = 0.001, d = -0.64, CI95 = -0.26 to -1.01) of male participants were stronger when compared to female participants but limb symmetry (male = 74.7±22.6%, female = 74.7±24.6%, p = 0.95, d = 0.00, CI95 = 0.36 to -0.36) and IKDC score (male = 84.4±16.1, female = 79.4±13.7, p = 0.08, d = -0.34, CI95 = 0.03 to -0.71) was not significantly different between the sexes. Male participants were 5.66 times (CI95 = 1.46 to 21.87) more likely to meet the clinical threshold for acceptable involved limb quadriceps strength and 3.52 times (CI95 = 1.54 to 8.05) more likely to report acceptable knee related function. The likelihood of achieving clinically acceptable limb symmetry was not significantly different between the sexes (OR = 1.17, CI95 = 0.48 to 2.83). Conclusion/Significance: Adolescent female patients may experience significantly worse involved limb and contralateral quadriceps weakness when compared to adolescent male patients despite displaying equally poor limb symmetry and patient-reported knee function during the first 12 month following surgery. Given the importance of involved limb quadriceps strength as a predictor of patient-reported function and movement quality, clinicians should incorporate patient education regarding the importance of quadriceps function and recommend progressive lower extremity loading when implementing patient-centered rehabilitation plans that promote safe return to healthy levels of physical activity following ACLR.