Vegetation net primary productivity (NPP) represents the ability of plants to fix ecosystem carbon, which is a key indicator to determine the health status and sustainable development of ecosystems. Its spatial and temporal changes and driving factors play an important role in revealing the status of vegetation restoration and guiding ecological restoration. Based on MODIS17A3 NPP data, land use, and meteorological data from 2001 to 2020, the temporal and spatial variation characteristics and driving factors of vegetation NPP in the Ulansuhai Nur Basin of Inner Mongolia were explored by using the methods of coefficient of variation, Theil-Sen Median trend analysis, Mann-Kendall significance test, Hurst index, and Geodetector. The results showed that: ① From 2001 to 2020, the vegetation NPP in the Ulansuhai Nur Basin showed a fluctuating upward trend, with an average value (in terms of C) of 141.03 g·(m2·a)-1 and an average increase rate of 2.33 g·(m2·a)-1. The vegetation NPP had obvious spatial differentiation, which was characterized by high in the southwest and low in the northeast and high in Hetao Plain and low in sandy land and mountainous areas. ② NPP mainly showed an increasing trend, and the area proportions of increasing, decreasing, and unchanged areas were approximately 80%, 3%, and 17%, respectively. The average coefficient of variation of vegetation NPP was 0.149, which mainly showed low fluctuation change, and the area accounted for approximately 51%. The future change trend of NPP was mainly characterized by anti-persistence, with an area ratio of approximately 75%. ③ Land use, altitude, maximum temperature, and slope were the dominant driving factors of variation NPP change in the Ulansuhai Nur Basin, and the q values were all above 0.200. The interaction between altitude and relative humidity had the greatest explanatory power for the spatial differentiation of vegetation NPP in the Ulansuhai Nur Basin. There were significant differences in the explanatory power of land use and all factors except nighttime light to the spatial differentiation of vegetation NPP in the Ulansuhai Nur Basin. According to the research results, in the future, we should strengthen the ecosystem management of the Ulansuhai Nur Basin; continue to implement strict ecological protection and restoration policies; and comprehensively consider factors such as climate, topography, and human activities to carry out comprehensive ecological management according to local conditions to improve the quality of ecosystem services.
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