Health Of People In China Research Articles

Eruption and caries status of first permanent molars in children aged 6–7 years in Shijingshan District, Beijing, China

BackgroundDental caries is still a major disease that affect the oral health of people in China. First permanent molars (FPMs) are the most caries-susceptible teeth among school-aged children. The aim of this study was to investigate the eruption and caries status of first permanent molars in children aged 6–7 years in Shijingshan District, Beijing, China, to provide information for oral health promotion.Methods The study was a cross-sectional survey conducted in 6-7-year-old first grade children from public elementary schools in Shijingshan District, Beijing. Participants were invited to receive a clinical oral examination. The eruption status and caries experience of FPMs were recorded. Questionnaires assessing children’s sociodemographic information and oral health-related behaviors were completed by the children’s parents or guardians.ResultsA total of 3,176 children, including 1,644 boys (51.8%) and 1,532 girls (48.2%) were included in the oral examination and questionnaire. Eruption status of FPMs was as follows: 37.5% fully erupted, 28.3% partially erupted, 34.2% not erupted. Girls had more erupted FPMs than boys (70.1% VS 61.8%, P < 0.001). The prevalence of dental caries in FPMs was 5.5% (174/3,176) in studied children. The mean decayed missing filled teeth score of FPMs was 0.11 and the mean decayed missing filled surface score of FPMs was 0.19. Binary Logistic regression analysis demonstrated that girls had more tooth decay than boys and father’s educational background also associated with the caries experience of the studied children (P < 0.05).ConclusionsAround two-thirds of FPMs were fully erupted or partially erupted among children aged 6–7 years old in Shijingshan District, Beijing. Approximately 5% of the newly erupted FPM established dental caries. Effective intervention should be applied in this age group for oral health promotion.

Treatment of non-small cell lung cancer based on the theory of lungs as the blood organ

Lung cancer has become one of the most common types of cancer, with high incidence and mortality rates persistently high. Among them, non-small cell lung cancer (NSCLC) is particularly common, accounting for up to 85% of lung cancer cases. NSCLC seriously endangers the health of people in China and around the world, and its specific causes are related to various factors such as smoking, radiation exposure, air pollution, and genetic factors. In traditional Chinese medicine, NSCLC belongs to the category of lung consolidation. Professor Zhang Wei believes that the lungs not only govern the qi of the body, but also play an important role in the generation and circulation of blood throughout the body, and has extensively expounded the viewpoint of lungs as the blood organ. This viewpoint is reflected in various functions of the lungs, such as the lungs controlling the hundred vessels, governing the storage of fluids, and controlling the skin and hair. The propulsion of lung qi also provides impetus for the normal circulation of blood. As the lungs serve as the blood organ and are prone to stasis, they are susceptible to the occurrence of lung consolidation. Therefore, the occurrence of NSCLC may be related to blood stasis in the lungs. Blood stasis is not only the pathological product of lung consolidation, but also the main cause of lung consolidation. It can be inferred that in the treatment of NSCLC, methods such as promoting blood circulation, dredging collaterals, and resolving phlegm and stasis should be adopted.

Clinical evaluation of a multitarget fecal immunochemical test-sDNA test for colorectal cancer screening in a high-risk population: a prospective, multicenter clinical study.

Colorectal cancer (CRC) is a major malignancy threatening the health of people in China and screening could be effective for preventing the occurrence and reducing the mortality of CRC. We conducted a multicenter, prospective clinical study which recruited 4,245 high-risk CRC individuals defined as having positive risk-adapted scores or fecal immunochemical test (FIT) results, to evaluate the clinical performance of the multitarget fecal immunochemical and stool DNA (FIT-sDNA) test for CRC screening. Each participant was asked to provide a stool sample prior to bowel preparation, and FIT-sDNA test and FIT were performed independently of colonoscopy. We found that 186 (4.4%) were confirmed to have CRC, and 375 (8.8%) had advanced precancerous neoplasia among the high CRC risk individuals. The sensitivity of detecting CRC for FIT-sDNA test was 91.9% (95% CI, 86.8-95.3), compared with 62.4% (95% CI, 54.9-69.3) for FIT (P<0.001). The sensitivity for detecting advanced precancerous neoplasia was 63.5% (95% CI, 58.3-68.3) for FIT-sDNA test, compared with 30.9% (95% CI, 26.3-35.6) for FIT (P<0.001). Multitarget FIT-sDNA test detected more colorectal advanced neoplasia than FIT. Overall, these findings indicated that in areas with limited colonoscopy resources, FIT-sDNA test could be a promising further risk triaging modality to select patients for colonoscopy in CRC screening.

Seizing the window of opportunity to mitigate the impact of climate change on the health of people in China

Seizing the window of opportunity to mitigate the impact of climate change on the health of people in China

Mean generation function model in AIDS epidemic estimation

BackgroundSince the first case of HIV infection was reported in China in 1985, the incidence and mortality of AIDS have been increasing rapidly, which has caused serious damage to the life and health of people in China and all over the world. Therefore, it is of great significance to study the technique for predicting AIDS morbidity and mortality. The purpose of this research is to explore the applicability of the mean generation function model (MGFM) in the early warning of AIDS morbidity and mortality, to predict its prevalence trend, to enrich the prediction techniques and methods of AIDS research and to provide suggestions for AIDS transmission control.MethodsIn this research, the MGFM was applied to predict the incidence and mortality of AIDS in China. AIDS incidence and mortality data in China from 2008 to 2019 were used to construct the prediction model.ResultsThe MGFM can predict the annual incidence and mortality of AIDS. The model constructed in this research predicted that the incidence and mortality of AIDS in China will continue to increase from 2020 to 2023.ConclusionThe mean birth function model was an effective method to monitor and predict the changing trend of AIDS incidence and mortality in China.

Long-Term Trends in Unintentional Fall Mortality in China: A Population-Based Age-Period-Cohort Study.

Background: Unintentional falls seriously threaten the life and health of people in China. This study aimed to assess the long-term trends of mortality from unintentional falls in China and to examine the age-, period-, and cohort-specific effects behind them.Methods: This population-based multiyear cross-sectional study of Chinese people aged 0–84 years was a secondary analysis of the mortality data of fall injuries from 1990 to 2019, derived from the Global Burden of Disease Study 2019. Age-standardized mortality rates of unintentional falls by year, sex, and age group were used as the main outcomes and were analyzed within the age-period-cohort framework.Results: Although the crude mortality rates of unintentional falls for men and women showed a significant upward trend, the age-standardized mortality rates for both sexes only increased slightly. The net drift of unintentional fall mortality was 0.13% (95% CI, −0.04 to 0.3%) per year for men and −0.71% (95% CI, −0.96 to −0.46%) per year for women. The local drift values for both sexes increased with age group. Significant age, cohort, and period effects were found behind the mortality trends of the unintentional falls for both sexes in China.Conclusions: Unintentional falls are still a major public health problem that disproportionately threatens the lives of men and women in China. Efforts should be put in place urgently to prevent the growing number of fall-related mortality for men over 40 years old and women over 70 years old. Gains observed in the recent period, relative risks (RRs), and cohort RRs may be related to improved healthcare and better education.

Applications of chromatography in giant complex drug-organism system

色谱是一门以分离分析为主,旨在追求复杂事物纯而净的分析化学的重要分支学科。其经过百余年的发展,理论与技术日臻完善,集科学、技术与艺术于一体。近年来,色谱及其与质谱、核磁共振波谱、原子发射光谱等联用技术极大推动了环境、食品、石油化工、生物医药等领域中所涉及复杂体系的研究进展。作为我国传统文化的核心代表,中医药为中国乃至世界人民的健康服务逾千年,从古至今历经上千年临床考验,疗效经久不衰。近年来,中国政府强调继承与创新,加大推进中医药的现代化与国际化。然而中药自身的多成分协同起效复杂性及其与机体时刻新陈代谢变化的复杂性往往相互作用,由此形成了药物-机体复杂巨系统。该复杂巨系统的分析研究是中医药现代化进程的关键瓶颈。色谱的优势在于复杂成分的分离与分析,此恰能为上述复杂巨系统提供技术支撑,色谱及其联用技术已成为推动中医药分子化、数字化、信息化乃至现代化的主流技术。该文综述了色谱及其联用技术在中药复杂体系、复杂生命过程及药物-机体复杂巨系统中的应用进展,介绍了笔者研究团队对中医药现代化的认识、研究思路和研究工作,最后笔者结合对于百年色谱与千年中医药文化之现代化交织的感悟,对色谱技术在此领域的前景做出了展望。

China guideline for the screening, early detection and early treatment of colorectal cancer (2020, Beijing)

Colorectal cancer (CRC) is a major malignancy threatening the health of people in China, which also leads to heavy social burden. A large number of researches and practices have demonstrated that screening and early detection are effective in reducing the mortality of CRC. It is therefore imperative to design guidelines for the screening, early detection and early treatment of CRC that are in line with national conditions of China based on international guideline development standard. In 2020, under the leadership of the National Cancer Center of China, a multidisciplinary guideline development group was established. The development of the guideline followed the principles and methods recommended by the World Health Organization. The guideline provides detailed recommendations for thirteen key clinical questions to which the professionals who are involved in screening, early detection and early treatment of colorectal cancer paid close attention. The guideline is intended to serve as a tool for professionals providing best decision-making on screening, early detection and early treatment of CRC and to enhance the effectiveness of CRC prevention and control in China.

Protease Inhibitor Use in COVID-19.

The outbreak of a large plaque, novel coronavirus pneumonia (NCP), which also named Coronavirus Disease 2019 (COVID-19) by the WHO, has detrimentally affected the livelihood and health of people in China. During the spread of COVID-19, colleagues who have been working at the frontline have had to face many new challenges in the treatment and prevention of NCP. Therefore, we have provided suggestions for the diagnosis, treatment, and prevention of the novel coronavirus pneumonia in the current epidemic situation based on the latest reports and the experience of doctors treating COVID-19 in our hospital. We recommend lopinavir/ritonavir as the effective drugs for antiviral treatment according to our experience in administering lopinavir/ritonavir to COVID-19 patients and the successful cases of these drugs in treating MERS and SARS, but need more clinical data to prove their efficacy in treating COVID-19.

The effect of religious belief on Chinese elderly health

BackgroundWith the accelerated ageing of the population in China, the health problems of elderly people have attracted much attention. Although religious belief has been shown to be a key way to improve the health of elderly people in various studies, little is known about the causal relationship between these variables in China. This paper explores the effect of religious belief on the health of elderly people in China, which will provide an important reference for China to achieve healthy ageing.MethodsBalanced panel data collected between 2012 and 2016 from the China Family Panel Studies (CFPS) were used. Health was assessed using self-rated health, and religious belief was measured by whether the respondents believed in a religion. The DID+PSM method was employed to solve the endogeneity problem caused by self-selection and omitted variables. In addition, the CESD score (replacing self-rated health) and different matching methods (the method of PSM after DID method) were used to perform the robustness test.ResultsThe results show that religious belief has no significant effect on the health of elderly people. With the application of different matching methods (one-to-one matching, K-nearest neighbour matching, radius matching and kernel matching) and replacing the health indicator (the CESD score) with the above matching methods, the results are still robust.ConclusionIn China, religious belief plays a limited role in promoting “healthy ageing”, and it is difficult to improve the health of elderly people only via religious belief. Therefore, except for focusing on the guidance of religion with regard to healthy lifestyles, multiple measures need to be taken to improve the health of elderly people.

Analysis of influential factors on air quality from global and local perspectives in China

Regional haze pollution has frequently occurred in China over the past several years, and this haze has hindered the development of the economy and harmed the health of people in China. Currently, several studies have analyzed the impact of different influencing factors on haze. However, few studies have comprehensively analyzed the influential factors of haze from different perspectives. In this paper, we utilized global and local regression models to explore the main influential factors on air quality index (AQI) in China from global and local perspectives. The results are as follows: (1) the AQIs of Chinese cities have significant positive spatial correlation, and higher values of AQI were typically found in Beijing-Tianjin-Hebei, Shandong, Henan, Shanxi and Shaanxi Province; (2) from a global perspective, as there is one unit of increase in the average AQI of one city's neighbors, the city's AQI will increase by 0.827 unit. An increase in the industrial structures and the number of civilian vehicles will also lead to an increase in the AQI, but the impact of precipitation is reversed; and (3) from a local perspective, there are spatial differences in the effects of different factors on the AQI. In northern China, an appropriate temperature reduction and an appropriate increase in atmospheric pressure is helpful for reducing haze pollution; however, opposing conditions are found in southern China. Compared with China's coastal cities, the increase in precipitation is more effective at reducing the AQI in inland cities. Compared with other cities, reducing the industrial structure and the number of civilian vehicles was more effective for haze management in Beijing, Tianjin, Shandong, Henan, Shanxi, and Shaanxi provinces. These results of this paper are helpful for government departments to formulate regionally differentiated governance policies regarding haze.

Controlling Air Pollution from Straw Burning in China Calls for Efficient Recycling

ir pollution is one aspect of the broader topic ofenvironmental issues in China. In the past decade, it hasbeen of concern due to rapid economic development.According to Dr. Nanshan Zhong, the president of the ChinaMedical Association, air pollution could become the greatestthreat to health of people in China. At the end of 2011, adebate, focusing on PM

Household stove improvement and risk of lung cancer in Xuanwei, China.

Lung cancer rates in rural Xuanwei County, Yunnan Province, are among the highest in China. Residents traditionally burned "smoky" coal in unvented indoor firepits that generated very high levels of air pollution. Since the 1970s, most residents have changed from firepits to stoves with chimneys. This study assessed whether lung cancer incidence decreased after this stove improvement. A cohort of 21 232 farmers, born from 1917 through 1951, was followed retrospectively from 1976 through 1992. All subjects were users of smoky coal who had been born into homes with unvented firepits. During their lifetime, 17 184 subjects (80.9%) changed permanently to stoves with chimneys. A hospital record search detected 1384 cases of lung cancer (6.5%) during follow-up. Associations of stove improvement with lung cancer incidence were analyzed with product-limit plots and multivariable Cox models. In 1995, indoor concentrations of airborne particles and benzo[a]pyrene were compared in Xuanwei homes during smoky coal burning in stoves with chimneys and in unvented stoves or firepits. A long-term reduction in lung cancer incidence was noted after stove improvement. In Cox models, risk ratios (RRs) for lung cancer after stove improvement were 0.59 (95% confidence interval [CI] = 0.49 to 0.71) in men and 0.54 (95% CI = 0.44 to 0.65) in women (for both, P<.001). Incidence reduction became unequivocal about 10 years after stove improvement. Levels of indoor air pollution during burning with chimneys were less than 35% of levels during unvented burning. Changing from unvented to vented stoves appears to benefit the health of people in China and may do so in other developing countries as well.

Screening for schistosome eggs by digital image processing

Schistosomiasis is an epidemic disease that seriously endangers the health of people in China. Therefore, it is advantageous to screen for scFwistosome eggs automatically. This paper describes a screening method implemented on the Leitz TAS+ image analysis instrument for the presence of schistosome eggs in fecal samples.