The education process is based on leading the choice of profession in line with the interests and abilities of the individual and helping them with their career plans in these professions. The aim of this study is to investigate the effect of the occupational interest levels of the Health Management Department students on their career commitment. In the study, descriptive findings were included by using a quantitative research design. In the research, data were collected from 282 students studying Department of Health Management. SPSS 26.0 package program was used for statistical analysis of research data. Parametric tests (t-test, analysis of variance, Pearson correlation analysis, normal linear regression analysis) were utilized since the data fit the normal distribution. 57.1% of the individuals participating in the research are female, 47.8% have the age range of 21 to 22. There is a positive, moderate (r = 0.677 p < 0.01) significant relationship between professional interest and career commitment scales. The level of professional interest and career dedication varies according to gender, age, income status and the class of the student. It is very important that health management students have an interest in their profession. Because this interest will guide them in what kind of a career they should make in their business life after graduation.