Head Of Inferior Turbinate Research Articles

Редкие причины назальной обструкции

Nasal obstruction can be influenced by numerous anatomical and physiological factors. For rhinosurgeons, it is important to know about the existence of such muscular and vascular components of the internal nasal valve (INV) region as the nasal septal swell body (NSB) and the nasal vestibular body (NVB) that – like other components of the INV – can take part in the development of the nasal obstruction. The body of the nasal septum is a glandular structure consisting of seromucous glands and venous sinusoids. It is associated with the area of the internal nasal valve and provides additional resistance to nasal airflow. The nasal vestibular body is an unstable dynamic vascular structure of the internal nasal valve, which is located on the inferolateral border of the area of the internal nasal valve, immediately in front of the head of inferior turbinate. There is currently no consensus regarding the surgery of these muscular and vascular components of the internal nasal valve for the treatment of nasal obstruction. However, the studies described in this review may indicate the effectiveness of surgical reduction of NSB and NVB. At the same time, other anatomical causes of nasal obstruction, such as hypertrophy of the inferior turbinate or deformation of the nasal septum, may interfere with the analysis of the described structures of the INV region, which may compromise the results of standard surgical interventions for nasal obstruction.

Correlation between acoustic rhinometry, computed rhinomanometry and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency

IntroductionTo provide clinical information and diagnosis in mouth breathers with transverse maxillary deficiency with posterior crossbite, numerous exams can be performed; however, the correlation among these exams remains unclear. ObjectiveTo evaluate the correlation between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency. MethodsA cross-sectional study was conducted in 30 mouth breathers with transverse maxillary deficiency (7–13 y.o.) patients with posterior crossbite. The examinations assessed: (i) acoustic rhinometry: nasal volumes (0–5cm and 2–5cm) and minimum cross-sectional areas 1 and 2 of nasal cavity; (ii) computed rhinomanometry: flow and average inspiratory and expiratory resistance; (iii) cone-beam computed tomography: coronal section on the head of inferior turbinate (Widths 1 and 2), middle turbinate (Widths 3 and 4) and maxilla levels (Width 5). Acoustic rhinometry and computed rhinomanometry were evaluated before and after administration of vasoconstrictor. Results were compared by Spearman's correlation and Mann–Whitney tests (α=0.05). ResultsPositive correlations were observed between: (i) flow evaluated before administration of vasoconstrictor and Width 4 (Rho=0.380) and Width 5 (Rho=0.371); (ii) Width 2 and minimum cross-sectional areas 1 evaluated before administration of vasoconstrictor (Rho=0.380); (iii) flow evaluated before administration of vasoconstrictor and nasal volumes of 0–5cm (Rho=0.421), nasal volumes of 2–5cm (Rho=0.393) and minimum cross-sectional areas 1 (Rho=0.375); (iv) Width 4 and nasal volumes of 0–5cm evaluated before administration of vasoconstrictor (Rho=0.376), nasal volumes of 2–5cm evaluated before administration of vasoconstrictor (Rho=0.376), minimum cross-sectional areas 1 evaluated before administration of vasoconstrictor (Rho=0.410) and minimum cross-sectional areas 1 after administration of vasoconstrictor (Rho=0.426); (v) Width 5 and Width 1 (Rho=0.542), Width 2 (Rho=0.411), and Width 4 (Rho=0.429). Negative correlations were observed between: (i) Width 4 and average inspiratory resistance (Rho=−0.385); (ii) average inspiratory resistance evaluated before administration of vasoconstrictor and nasal volumes of 0–5cm (Rho=−0.382), and average expiratory resistance evaluated before administration of vasoconstrictor and minimum cross-sectional areas 1 (Rho=−0.362). ConclusionThere were correlations between acoustic rhinometry, computed rhinomanometry, and cone-beam computed tomography in mouth breathers with transverse maxillary deficiency.

The effects of pregnancy on nasal physiology.

Nasal congestion that is not present before pregnancy represents a distinct clinical entity called pregnancy rhinitis. The aim of this study is to evaluate the clinical characteristics of nasal physiology over the course of pregnancy. The study was conducted with 85 pregnant women and 26 nonpregnant controls. We measured nasal airway patency objectively via acoustic rhinometry (ARM) and anterior rhinomanometry (RMM) and subjectively via the Nasal Obstruction Symptom Evaluation (NOSE) scale in each trimester and compared the results to those of the controls. The NOSE scores of control and pregnant women showed no difference (p = 0.866). Minimal cross-sectional area (MCA1; minimal cross sectional area at nasal valve and MCA2; minimal cross sectional area at the level where the head of inferior turbinate is placed) decreased significantly between the first and third trimesters: first trimester 0.37 cm(2), third trimester 0.31 cm(2). There was no difference between each trimester with regard to total nasal resistance. The correlation analysis between the NOSE score and both total volume and MCA1 in all patients showed no significance (r = -0.10, p = 0.318; r = -0.04, p = 0.654, respectively). Pregnancy affects nasal physiology adversely and impairs nasal breathing in some women. However, based on the findings of this study, we concluded that this clinical entity may not be considered as a disease without complementary symptoms despite the presence of objective changes in nasal parameters.

What is normal nasal airflow? A computational study of 22 healthy adults.

Nasal airflow is essential for the functioning of the human nose. Given individual variation in nasal anatomy, there is yet no consensus what constitutes normal nasal airflow patterns. We attempt to obtain such information that is essential to differentiate disease-related conditions. Computational fluid dynamics (CFD) simulated nasal airflow in 22 healthy subjects during resting breathing. Streamline patterns, airflow distributions, velocity profiles, pressure, wall stress, turbulence, and vortical flow characteristics under quasi-steady state were analyzed. Patency ratings, acoustically measured minimum cross-sectional area (MCA), and rhinomanometric nasal resistance (NR) were examined for potential correlations with morphological and airflow-related variables. Common features across subjects included: >50% total pressure drop reached near the inferior turbinate head; wall shear stress, NR, turbulence energy, and vorticity were lower in the turbinate than in the nasal valve region. However, location of the major flow path and coronal velocity distributions varied greatly across individuals. Surprisingly, on average, more flow passed through the middle than the inferior meatus and correlated with better patency ratings (r = -0.65, p < 0.01). This middle flow percentage combined with peak postvestibule nasal heat loss and MCA accounted for >70% of the variance in subjective patency ratings and predicted patency categories with 86% success. Nasal index correlated with forming of the anterior dorsal vortex. Expected for resting breathing, the functional impact for local and total turbulence, vorticity, and helicity was limited. As validation, rhinomanometric NR significantly correlated with CFD simulations (r = 0.53, p < 0.01). Significant variations of nasal airflow found among healthy subjects; Key features may have clinically relevant applications.

Measurements of normal nasal airway assessed by 3-dimensional computed tomography in Chinese children and adolescents

ObjectiveTo establish normative data of nasal airway dimensions in Chinese children and adolescents by age and sex. MethodsCT images of 281 Chinese children and adolescents (140 girls and 141 boys) aged from 6 to 18 years (yr) were selected among the patients who visited in Shanghai Ninth People's Hospital from September 2009 to August 2010. Subjects were divided into four age groups as group 1 (6–9yr), group 2 (10–12yr), group 3 (13–15yr), and group 4 (16–18yr). Child was defined as 6–12yr, and adolescent as 13–18yr. Nasal parameters were as follow: nasal volume (NV), length of nasal airway (NL), minimal cross-section area (CSA 1) and its location (D 1), inferior turbinate head's location (D 2) and its airway cross-section area (CSA 2), and cross-sectional area of choanal (CSA 3). ResultsThere was no significant sex dimorphism in nasal parameters in children (group 1 and group 2). In adolescents, male's nasal dimension were larger than female's. CSA 1, D 1, CSA 2, CSA 3, NL and NV correlated with age in male and female respectively. ConclusionsVolume, length and cross-section area of nasal airway were correlated with age in Chinese children and adolescents aged from 6 to 18yr. In children, nasal conformations of male and female are similar. In adolescents, sex dimorphisms in nasal parameters were significant.

Does nasal obstruction affect the articulation of plosive consonants?

In this study, we investigated the impact of chronic nasal obstruction on articulation of the Turkish voiceless plosive (stop) consonants and examined the effect of the nose- and mouth-breathing on the articulatory characteristics of the specific speech sounds. Twenty-one controls with nose-breathing and 20 patients with mouth breathing were included in this study. The nasal obstruction history of the patients was 10 to 22 years. In the mouth-breather group, intranasal pathologies except septal deviation and turbinate hypertrophy were excluded. The nose-breather subjects without nasal pathologies served as the control group. The subjects graded nasal obstruction through visual analog scale (VAS) from 0 to 10. The minimal cross-sectional area (MCA) and minimal cross-sectional volume (MCV) at the level of septal tubercle and the head of inferior turbinate were established to be 1 and 2 by acoustic rhinometry. Minimal cross-sectional volume was defined as the volume below the curve. The syllables [pa], [ta], [ka] uttered by the subjects were recorded for the spectrographic analysis. Voice onset time (VOT) was measured on wide-band spectrogram. The VOT value of /p/ was found lower and the VOT values for /t/ and /k/ were found higher in mouth-breathers compared to nose-breathers, while the difference was not statistically significant. The right and left-sided VAS values of the nasal obstruction group were significantly higher compared to controls (p=0.001). The right and left-sided MCA1, MCA2, MCV1 and MCV2 were found statistically different between the two groups. It was concluded that the articulation features of plosive consonants were not significantly affected by nasal obstruction.

Influence of uncinate process on aerodynamic characteristics of nasal cavity and maxillary sinus

This study aimed to investigate the influence of uncinate process on air flow velocity, trace, distribution, air pressure, as well as the air flow exchange of nasal cavity and paranasal sinuses. Fluent software was used to simulate two nasal cavity and paranasal sinus structures following CT scanning, one had normal nasal cavity, the another had the nasal cavity with uncinate process removed. Air flow velocity, pressure, distribution and trace lines were calculated and compared by Navier-Stokes equation and numerically visualized between two models. Air flow of two models in the common and middle meatus accounted for more than 50% and 30% of total nasal cavity flow. Flow velocity of two models were maximal in the common meatus, followed by the middle meatus. The maximal velocity existed on the left nasal district between limen nasi and head of inferior turbinate. The flow traces of two models were similar. In the normal model, the air flow velocity of the district around uncinate process was almost the same in inhale and exhale. In the model with the uncinate process removed, the air flow velocity of the district around uncinate process was faster, the air flow velocity in expiratory phase was quicker. Compared with the normal nasal cavity, there was more exchange of maxillary sinus in the model with cut uncinate process. In the view of flow dynamics, the uncinate process effects the air flow velocity of the district around uncinate process and the exchange of maxillary sinus, the contribution of nasal flow is connected with the morphosis of the uncinate process.

Comparative Study on the Long‐Term Effectiveness Between Coblation‐ and Microdebrider‐Assisted Partial Turbinoplasty

Various surgical methods have been tried to relieve the symptoms of nasal obstruction in patients with inferior turbinate hypertrophy. Recently, coblation that uses the radiofrequency and microdebrider is being increasingly used in turbinate surgery. The aim of this study was to compare the long-term postoperative outcome between the coblation- and microdebrider-assisted partial turbinoplasty. We selected 60 patients for this prospective study who had nasal obstruction and hypertrophied turbinate mucosa that was refractory to medical treatment. Thirty patients were treated with coblation (group 1) and 30 patients were treated with microdebrider (group 2). Postoperative changes in degree of nasal obstruction were evaluated prospectively at 3, 6, and 12 months after the procedure. A cross-sectional area of second notch and volume of nasal cavity were compared at 12 months after operation. Operation time, duration of crust formation, postnasal drip, and postoperative bleeding were also compared. Nasal obstruction was improved significantly in both groups at 3, 6, and 12 months after the procedure. However, when compared between two groups, symptom improvement was statistically significant in group 2 at 12 months after surgery. Acoustic rhinometry performed at 12 months demonstrated a significant increase of cross-sectional area of second notch and volume of nasal cavity in group 2 in comparison with group 1. There were no significant differences in degree of postnasal drip, operation time, or duration of crust formation between the two groups. This study suggests that microdebrider-assisted partial turbinoplasty is more effective and satisfactory in long-term relief of nasal obstruction and reduction in mucosal volume of anterior head of inferior turbinate.

Epstein-barr virus induced cellular changes in nasal mucosa

A 21-year-old man presented with nasal obstruction of the right nasal fossa of 1 year duration. Nasal endoscopy revealed in the right inferior turbinate head a rounded neoplasm about 1 cm in diameter.Cytologic study of a nasal scraping specimen disclosed numerous clusters containing columnar cells with cytomegaly, prominent multinucleation, markedly sparse shortened cilia; the cytoplasm contained an acidophil area and a small round area that stained poorly; cells with a large intracytoplasmic vacuole that was acidophil and PAS+. Serology tests using the nested polymer chain reaction (PCR) technique on serum, nasal and pharyngeal smears revealed an Epstein-Barr virus (EBV) infection that was confirmed at electron microscopy. The clinical and cytological features resolved 19 months after the initial evaluation.ConclusionThe authors advise carrying out clinical (endoscopy, serology, etc.) evaluation of all endonasal neoplasms and to routinely perform cytological study on nasal scraping specimens. When samples test positive for EBV, nasal and nasopharyngeal endoscopy should be performed regularly to detect possible evidence for nasopharyngeal carcinoma (NPC).

Study and application of a mathematical model for the provisional assessment of areas and nasal resistance, obtained using acoustic rhinometry and active anterior rhinomanometry.

Nasal resistance (NR) depends on the geometrical features and tortuosity of the nasal airway and on the air flow. Knowing the longitudinal distribution of cross-sectional areas (CSAs) in the nasal cavity (which can be obtained using acoustic rhinometry) and the laminar nasal resistance (obtainable by processing the rhinomanometric results), it is possible to calculate, utilizing a mathematical model elaborated on the basis of fluid dynamics, the differential nasal resistance (NRdiff) and the cumulative nasal resistance (NRcum), thus localizing the position at which the highest resistance is concentrated and the related longitudinal distribution. Using a mathematical model, we integrated the sigmoid curves DeltaP/Q of rhinomanometry with the cross-sectional areas obtained using acoustic rhinometry, thus obtaining the normal distribution of differential and cumulative nasal resistances. Afterwards, we empirically reduced the cross-sectional areas corresponding to the head, body, tail and the whole inferior turbinate, recalculating the differential and cumulative nasal resistance distribution curves. The results show that reduction of up to 50% of cross-sectional areas does not substantially affect the resistivity role of the nasal valve, while greater reductions move the highest resistivity point to an area at the junction of the body and the head of the inferior turbinate. The study of the differential nasal resistance trend curves as a function of the reduction of cross-sectional areas shows that the resistance variation of the body and the whole inferior turbinate prevail with reductions of up to 40%, while the variation of cross-sectional areas of the body bordering the inferior turbinate head is predominant with higher reductions. The cross-sectional areas of the nasal airway cavity with highest resistivity are mainly located in an anterior position, where the differential nasal resistances are higher, but there are substantial variations produced by reducing the cross-sectional area of the posterior nasal airway. A similar model can produce provisional values for the results obtainable with functional nasal surgery.