To satisfy rising data capacity and bandwidth demands, Pulse Amplitude Modulation with 4 levels (PAM4) has become a popular signaling system in high-speed digital communication. As contemporary hardware designs restrict Non-Return-to-Zero (NRZ) signaling, PAM4 offers an appealing alternative by doubling data flow within the same bandwidth. Using PAM4 signaling provides distinct characterisation and validation problems that must be addressed to assure dependable performance in modern hardware systems. Modern hardware designs' PAM4 signaling characterisation and validation are covered in this research report. PAM4 signaling fundamentals, including modulation technique, signal integrity, and high-speed data transfer, are examined in the research. PAM4's higher data rates and spectrum efficiency are highlighted in the article, along with its implementation issues. Much of the study characterizes PAM4 signaling. This involves developing reliable signal measuring methods, analyzing signal loss owing to ISI and jitter, and assessing PAM4 performance based on hardware components. PAM4 signal behavior under diverse settings is characterized using advanced methods as eye diagram analysis, constellation diagram evaluation, and error vector magnitude (EVM) measurement. The paper tests and simulates PAM4 signaling to validate it. A thorough approach for testing PAM4 performance in lab and real-world conditions is provided. PAM4 signaling resilience in different hardware contexts is tested using specialist test equipment and simulation tools. The validation method includes BER, SNR, and industry standard compliance.The study also examines how new hardware design affects PAM4 signaling. Advanced circuit design, packaging, and material qualities affect signal integrity and performance. High-speed data interface designers and engineers may learn from the paper's ideas for reducing signal degradation and improving PAM4 signaling in complicated hardware systems.