A field experiment was conducted in a Typic Haplaquept soil of West Bengal, India to study the influence of combined application of inorganic and organic fertilizers on yield and quality parameters of Rapeseed (Brassica Campestris L. Var. Yellow Sarson). Recommended doses of N, P and K were applied to all the treated plots (5m X 4m). FYM was applied at 5 ton ha-1 to all the plots except control. Two doses of S (20 and 40kgha-1) and two doses of B (0.5 and 1.0 kgha-1) were included in the treatment combinations. Rhizosphere soil and plant samples were collected at branching, pod formation and harvesting stages of rapeseed. Rhizosphere soil were analyzed for available S and B content. Plant samples were also analyzed for S and B uptake following standard methods. Results of the present investigation revealed that in general, the amount of S and B in soil decreased with increase in the period of crop growth. Comparatively higher uptake of S and B were recorded by rapeseed crop which received recommended doses of N, P and K (RDF) along with organic matter as well as higher doses of S and B (T9). Highest seed yield (13.79%) as well as oil (42.57%) and protein contents (21.76%) over control were recorded in rapeseed which received RDF along with organic matter as well as higher doses of S and B (T9). Furthermore, it is noteworthy to mention that the application of organic matter along with S and B increased oil and protein content in rapeseed significantly.