We investigate the possibility to obtain higly multipartite-entangled states as non-degenerate eigenstates of Hamiltonians that involve only short-range and few-body interactions. We study small-size systems (with a number of qubits ranging from three to five) and search for Hamiltonians with a maximally multipartite entangled state (MMES) as a non-degenerate eigenstate. We then find conditions, including bounds on the number of coupled qubits, to build a Hamiltonian with a Greenberger–Horne–Zeilinger (GHZ) state as a non-degenerate eigenstate. We finally comment on possible applications.