ABSTRACT Detailed analysis of over 1,000 subsurface Silurian palynology samples from 34 wells has allowed the development of a robust biostratigraphy based on acritarchs, chitinozoans and cryptospores for the Qusaiba Member of the Qalibah Formation, central Saudi Arabia. The new index fossils described herein augment the Arabian Plate Silurian chitinozoan zonation. The high-resolution biostratigraphic zonation consists of nine First Downhole Occurrences (FDOs) from the lower Telychian through Aeronian. In particular, three regionally recognizable palynologic horizons were identified within the lower part of the informally designated Mid-Qusaiba Sandstone (Angochitina hemeri Interval Zone), and above the FDO of Sphaerochitina solutidina. This high level of biostratigraphic resolution provides a framework for the integration of the sedimentology and calibration with global sea level curves, leading to a detailed understanding of the sequence stratigraphic evolution of this part of the Silurian in Saudi Arabia. Sedimentological core studies identify three Depositional Facies Associations (DFAs) within the Mid-Qusaiba Sandstone interval, including: (1) shelfal deposits (DFA-I) characterized by interbedded hummocky cross-stratified sandstones, graded siltstones and bioturbated mudstones; (2) turbiditic deposits (DFA-II); and (3) an association of heavily contorted and re-sedimented sandstones, siltstones and mudstones (DFA-III) that is considered representative of oversteepened slopes upon the Qusaiba shelf. Integration of the newly recognized palynostratigraphic horizons and the sedimentological data facilitates an understanding of the sequence stratigraphic evolution of the Mid-Qusaiba Sandstone interval and its immediate precursors. Thus a Maximum Flooding Surface (MFS) is identified from significant palynostratigraphic, as well as sedimentological evidence, and concurs with the MFS identified regionally with the Monograptus convolutus Graptolite Zone. Several mud-prone cyclothems downlap onto the MFS. Each of these is identified by its own palynostratigraphic marker: these mud-prone cyclothems represent the distal parts of a Highstand Systems Tract (HST). The end of the HST is marked by evidence of a major, episodic drop in relative sea level. Thus, a relationship is identified wherein successive palynostratigraphic marker horizons, newly identified in this study, are partially eroded by the introduction of sandy turbidites (DFA-II). These turbidites arise from storm-induced erosion of gully complexes in the upper submarine slopes that are present as topography upon the Qusaiba shelf. Each of the successive drops in sea level is separated from the next by a minor, subsequent sea level rise, which precludes further submarine erosion and turbidite deposition, and is instead evident in the widespread occurrence of shallow marine (shelfal) muds and sandy tempestites (DFA-I). The lowstand per se is considered to be represented by the most widespread distribution of the DFA-II turbidite deposits, and is associated with the youngest Mid-Qusaiba Sandstone marker horizon identified in this study, namely Rugosphaera agglomerata n.sp. The youngest unit of DFA-II lowstand turbidites is limited in its occurrence to the more proximal parts of the study area, and thus is considered to represent the onset of the succeeding Transgressive Systems Tract (TST). Of the biostratigraphic indices used for correlation within the Qusaiba Member, Rugosphaera agglomerata and Eupoikilofusa curvata are formally described and two additional important species, Fractoricoronula n.sp. and ?Oppilatala n.sp., are retained in open nomenclature.