Ground collapse caused by defective pipelines has become a global issue with the continuous advancement of urbanization. This study reproduced the internal erosion process of sand-fines mixtures around defective pipes through a series of model tests considering a relatively wide range of fines content and three hydraulic conditions. The erosion characteristics and the evolution of the cavity were analyzed to determine the triggering mechanisms of ground collapse. The results indicate that the formation and evolution of the cavity predominantly depend on fines content under hydraulic loading, which is replaced by ground settlement at lower fines content. Moreover, the scouring of groundwater amplifies the impact of internal erosion, which means the marked ground settlement at lower fines content or the expansion of the cavity even to ground collapse at higher fines content. To prevent sudden ground collapse, it is not recommended to use sand-fines mixtures with a fines content of more than 10% as embedment materials.