Undesirable hydrodynamic properties are inevitable in the traditional grinding process, which often provides a harsher lubrication environment. This paper introduces combinatorial bionics to optimize the hydrodynamic properties of grinding tools innovatively. Two bionic prototypes (phyllotaxis arrangement and fish scale) with special hydrodynamic properties are organically integrated to help design a combinatorial bionic grinding wheel (CBGW). The CBGW can more effectively inhibit the adverse effects of air turbulence on the grinding process and maintain a higher useful flow rate with a maximum improvement rate of 290.47%. This study enhances the effectiveness of grinding fluids from the perspective of grinding wheel structure and provides an excellent tribological basis for green and high-efficiency grinding.