This study is focused on the effects of the new standard of the building design under seismic loading in Thailand (DPT 1302-52) on cost estimates and the seismic performance of nine-story reinforced concrete apartment buildings with various ductility in moderate seismic zone and a gravity load designed (GLD) building. Both the nonlinear static pushover and nonlinear dynamic analyses are applied. Comparisons of performance point (PF) evaluation of studied frames are investigated by three different methods, namely, capacity spectrum method (CSM), inelastic demand diagram method (IDDM), and nonlinear time history analysis (NTHA) method. Five selected ground motion records are investigated in the analyses. In order to examine the influence of design ductility classes, the seismic forces on moment resisting frame buildings are defined according to the new standard of the building design under seismic loading in Thailand with ductility from 8, 5, and 3, corresponding to special ductile frame (SDF), intermediate ductile frame (IDF), and ordinary ductile frames (ODF), respectively. For the cost estimates, ODF is the most expensive among ODF, IDF, and SDF. Costs of SDF and IDF in Chiang Mai are quite similar. The results show that SDF is more ductile than that of ODF, however, the strength of SDF is less than ODF. The results indicate that all frames including GLD are able to withstand a design earthquake. The study also found that the average ductilities at the failure state for SDF, IDF, ODF, and GLD are 1.45, 1.42, 1.28, and 1.17, respectively. The average PGAs at the failure state for SDF, IDF, ODF, and GLD are 0.85 g, 0.83 g, 0.63 g, and 0.35 g, respectively when these buildings have the volumetric ratio of horizontal confinement within joint panel greater than 0.003. Moreover, at the failure state of GLD with volumetric ratio of horizontal confinement within joint panel less than 0.003, the average PGA is only 0.17 g which is lower than the design earthquake of PGA of 0.39 g in the draft DPT. The SDF and IDF are the two best options in consideration of cost and seismic performance.