Abstract The Laser Interferometer Space Antenna (LISA) will observe gravitational-wave signals from a wide range of sources, including massive black hole binaries. Although numerous techniques have been developed to perform Bayesian inference for LISA, they are often computationally expensive; analyses often take at least $\sim 1$ month on a single CPU, even when using accelerated techniques. Not only does this make it difficult to concurrently analyse more than one gravitational-wave signal, it also makes it challenging to rapidly produce parameter estimates for possible electromagnetic follow-up campaigns. simple-pe was recently developed to produce rapid parameter estimates for gravitational-wave signals observed with ground-based gravitational-wave detectors. In this work, we extend simple-pe to produce rapid parameter estimates for LISA sources, including the effects of higher order multipole moments. We show that simple-pe infers the source properties of massive black hole binaries in zero-noise at least $\sim 100\times$ faster than existing techniques; $\sim 12$ hours on a single CPU. We further demonstrate that simple-pe can be applied before existing Bayesian techniques to mitigate biases in multi-modal parameter estimation analyses of MBHBs.