Age Gradient Research Articles

Research and prediction of early-age loads in double-block ballastless track structure

Considering the hydration reaction of cement, a finite element model(FEM) of the coupling of temperature and humidity field and chemical field in the early age of the double-block ballastless track structure was established, and a field monitoring test on the early age of track slab was carried out with the newly constructed Fuzhou-Xiamen high-speed railway line as a case to verify the correctness of the FEM. Based on the official meteorological data from China Meteorological Administration (CMA) and the FEM, the dataset of vertical temperature and humidity gradients in the early age of the track slab was constructed, and five machine learning training models, namely, machine learning (MLR), multivariate polynomial regression (MPR), support vector regression (SVR), random forest (RF), and gradient boosted regression (GBR), were adopted to train the temperature gradient model and humidity gradient model for the early age of the track slab. The research results show that: (1) under the combined effect of solar radiation, convective heat transfer, radiative heat exchange and the cement hydration reaction, the temperature loading leads to the susceptibility of the sleepers to diagonal cracking; the humidity loading leads to transverse cracking in the center region of the surface of the track slab; (2) the finite element model with a higher accuracy provided the training dataset for the machine learning model. According to the Spearman correlation coefficient, the input features of the temperature gradient model and the humidity gradient model are determined, respectively; (3) Five ML methods were used to train the temperature gradient model and humidity gradient model, both of which demonstrated good generalization ability with a coefficient of determination(R2) greater than 0.85. Among these methods, GBR and SVR exhibited the best performance; From the perspective of MAPE value, the prediction effect of the temperature gradient training model was better than that of the humidity gradient training model; (4) The curing method and the average value of the relative humidity were the important input features influencing the training models for the temperature and humidity gradient loads, respectively. This finding provided an important guideline for the construction of ballastless track structures.

Association between impaired left ventricular global longitudinal strain and B-type natriuretic peptide in obstructive hypertrophic cardiomyopathy

Abstract Background Left ventricular global longitudinal strain (LV-GLS) is considered valuable in explaining impaired left ventricular contractility in hypertrophic cardiomyopathy (HCM) with preserved ejection fraction and is associated with worse outcome. Elevated B-type natriuretic peptide (BNP) is a biomarker of increased LV wall stretch and a risk factor of heart failure, mortality, and other adverse cardiovascular events. However, relationship between GLS and BNP has not received sufficient attention in the obstructive variant of HCM. Purpose This study aimed to determine the association between echocardiographic LV-GLS and plasma BNP in patients with hypertrophic obstructive cardiomyopathy (HOCM). Methods A total of 145 consecutive patients (32% females) with symptomatic HOCM were enrolled in the retrospective study. HOCM was defined with a maximum end-diastolic wall thickness ≥15mm without other etiologies for LV hypertrophy, and peak LV outflow tract (LVOT) gradient ≥30mmHg. The echocardiographic parameters regarding LV geometry, loading conditions, and GLS were evaluated according to guidelines. Patients were divided into two groups according to absolute GLS values (greater or lower than median LV-GLS). Patient baseline clinical data, echocardiographic parameters, and BNP were compared. Univariate and multivariable regression analysis were applied to identify the independent determinator of LV-GLS. Results The median value of LV-GLS of this study cohort was -13.4%. Eighty-one patients (47.6±13.4 years-old) had a |GLS|≥13.4% and 64 individuals (48.7±12.6 years-old) had a |GLS|<13.4%. No differences were found in age, gender, physical examinations, LVEF, cardiovascular comorbidities, or active medications between the two groups, except for body mass index (BMI). Patients with |GLS|≥13.4% had statistically lower BMI (24.58±2.42 vs. 26.00±3.12kg/m², p=0.030). BNP was found significantly elevated in patients with |GLS|<13.4% when compared with individuals with |GLS|≥13.4% {median (IQR); 550.05 (214.50, 899.35) vs. 182.40 (78.90, 479.90)pg/mL, p=0.004}. In univariate regression analysis, decreased |GLS| was associated with male gender, maximum and mean LV wall thickness, peak LVOT gradient, reduced mitral annular e’ velocity, elevated BNP and cardiac troponin I. In multivariable regression analysis, GLS was found independently associated with mean LV wall thickness and BNP. Conclusions In patients with symptomatic HOCM with preserved ejection fraction, impaired LV-GLS was found to be associated with plasma BNP and mean LV wall thickness, independent of gender, age, loading conditions, LVEF, or LVOT gradient. Reduced GLS may be a more sensitive surrogate in assessing increased myocardial wall tension or stretch, rather than LV contractility in these patients. Therefore, the interpretation of GLS in HOCM should shift away from systolic interest toward emphasizing its potential value in risk stratification of diastolic heart failure with preserved LVEF.Figure 1

Quality of Life among the Sámi Population

Abstract Introduction The Sámi, indigenous to Northern Europe, maintain rich traditions like reindeer herding and unique languages. Continuous efforts are made to preserve their cultural identity and practices. Systemic barriers, including cultural marginalization and environmental challenges, exacerbate these inequalities, impacting their ability to preserve traditional lifestyles. It is not known, until now, how this impacts Quality of Life (QoL). Aims Describe QoL in the Sámi population in Norway Methods In 2019/20, the three northernmost Counties in Norway took part in the Norwegian Counties Public Health Surveys (NCPHS), which also has a comprehensive QoL module (comprises subjective and objective measures, Cantril scale). NCPHS is an internet-based survey. On average 25 % of the adult population was invited to participate in the NCPHS. Results Being Sámi was through self-identification, n = 3312. Satisfaction with Life was 7,34 versus 7,41 for the general population. For Loneliness, 15,9 % percent of the Sámi were characterized as lonely (score 6-10) versus 13,3 %, and for positive emotions, there was no difference, with a score of 6,69 for both groups. Sex, age and educational gradients are similar to the general population, for all measures. Minor differences were found according to if one lived in a Sámi-majority municipality or not. Conclusions Overall, being Sámi is associated with slightly lower QoL on several measures, but effect sizes are general small to insignificant. Due to lack of data on the Southern Sámi population, findings cannot be generalized to all Sámi. Key messages • Overall, being Sámi is associated with slightly lower QoL on several measures, but effect sizes are general small to insignificant. • Due to lack of data on the Southern Sámi population, findings cannot be generalized to all Sámi.

Scylla. III. The Outside-in Radial Age Gradient in the Small Magellanic Cloud and the Star Formation Histories of the Main Body, Wing, and Outer Regions

The proximity of the Large and Small Magellanic Clouds (LMC and SMC) provides the opportunity to study the impact of dwarf–dwarf interactions on their mass assembly with a unique level of detail. To this end, we analyze two-filter broadband imaging of 83 Hubble Space Telescope (HST) pointings covering 0.203 deg2 toward the SMC, extending out to ∼3.5 kpc in projection from its optical center. Lifetime star formation histories (SFHs) fit to each pointing independently reveal an outside-in age gradient such that fields in the SMC outskirts are older on average. We measure radial gradients of the look-back time to form 90%, 75%, and 50% of the cumulative stellar mass for the first time, finding δ(τ 90, τ 75, τ 50)/δ R = (0.61 −0.07+0.08 , 0.65−0.08+0.09 , 0.82−0.16+0.12 ) Gyr kpc−1 assuming PARSEC evolutionary models and a commonly used elliptical geometry of the SMC, although our results are robust to these assumptions. The wing of the SMC deviates from this trend, forming 25% of its cumulative mass over the most recent 3 Gyr owing to a best-fit star formation rate that remains approximately constant. Our results are consistent with chemodynamical evidence of a tidally stripped SMC component in the foreground and imply contributions to the observed SFH from multiple previous LMC–SMC interactions. We also compare our SMC SFH with results from a companion study of the LMC, finding that while the two galaxies present different internal, spatially resolved SFH trends, both the LMC and SMC have similar near-constant lifetime SFHs when viewed globally.

Scylla. II. The Spatially Resolved Star Formation History of the Large Magellanic Cloud Reveals an Inverted Radial Age Gradient

The proximity of the Magellanic Clouds provides the opportunity to study interacting dwarf galaxies near a massive host, and spatial trends in their stellar population properties in particular, with a unique level of detail. The Scylla pure parallel program has obtained deep (80% complete to >1 mag below the ancient main-sequence turnoff), homogeneous two-filter Hubble Space Telescope imaging sampling the inner star-forming disk of the Large Magellanic Cloud (LMC), the perfect complement to shallower, contiguous ground-based surveys. We harness this imaging together with extant archival data and fit lifetime star formation histories (SFHs) to resolved color–magnitude diagrams of 111 individual fields, using three different stellar evolutionary libraries. We validate per-field recovered distances and extinctions, as well as the combined global LMC age–metallicity relation and SFH against independent estimates. We find that the present-day radial age gradient reverses from an inside-out gradient in the inner disk to an outside-in gradient beyond ∼2 disk scale lengths, supported by ground-based measurements. The gradients become relatively flatter at earlier look-back times, while the location of the inversion remains constant over an order of magnitude in look-back time, from ∼1 to 10 Gyr. This suggests at least one mechanism that predates the recent intense LMC–Small Magellanic Cloud interaction. We compare observed radial age trends to other late-type galaxies at fixed stellar mass and discuss similarities and differences in the context of potential drivers, implying strong radial migration in the LMC.

Stellar Metallicities and Gradients in the Faint M31 Satellites Andromeda XVI and Andromeda XXVIII

We present ∼300 stellar metallicity measurements in two faint M31 dwarf galaxies, Andromeda XVI (M V = −7.5) and Andromeda XXVIII (M V = –8.8), derived using metallicity-sensitive calcium H and K narrowband Hubble Space Telescope imaging. These are the first individual stellar metallicities in And XVI (95 stars). Our And XXVIII sample (191 stars) is a factor of ∼15 increase over literature metallicities. For And XVI, we measure 〈[Fe/H]〉=−2.17−0.05+0.05 , σ[Fe/H]=0.33−0.07+0.07 , and ∇[Fe/H] = −0.23 ± 0.15 dex Re−1 . We find that And XVI is more metal-rich than Milky Way ultrafaint dwarf galaxies of similar luminosity, which may be a result of its unusually extended star formation history. For And XXVIII, we measure 〈[Fe/H]〉=−1.95−0.04+0.04 , σ[Fe/H]=0.34−0.05+0.05 , and ∇[Fe/H]= −0.46 ± 0.10 dex Re−1 , placing it on the dwarf galaxy mass–metallicity relation. Neither galaxy has a metallicity distribution function (MDF) with an abrupt metal-rich truncation, suggesting that star formation fell off gradually. The stellar metallicity gradient measurements are among the first for faint (L ≲ 106 L ⊙) galaxies outside the Milky Way halo. Both galaxies’ gradients are consistent with predictions from the FIRE simulations, where an age–gradient strength relationship is the observational consequence of stellar feedback that produces dark matter cores. We include a catalog for community spectroscopic follow-up, including 19 extremely metal-poor ([Fe/H] < –3.0) star candidates, which make up 7% of And XVI’s MDF and 6% of And XXVIII’s.

Gender and socioeconomic dimensions of relative age effects on ADHD prescriptions: Evidence from Denmark

This paper examines the impact of relative age on Attention Deficit Hyperactivity Disorder (ADHD) prescriptions among school-aged children. Using a regression discontinuity design, we leverage the quasi-experimental variation in school starting age. We use administrative data for all children aged 6–16 from 2010 to 2019 in Denmark. We find a significant decrease in ADHD prescription rates for girls who are relatively old compared to their class mates. We do not find any significant results for boys. We further test the social gradient in relative age on ADHD prescriptions and find that the effect is entirely driven by girls from low income families.

Spatially correlated stellar accretion in the Lupus star-forming region. Evidence for ongoing infall from the interstellar medium

Growing evidence suggests that protoplanetary discs may be influenced by late stage infall from the interstellar medium (ISM). It remains unclear the degree to which infall shapes disc populations at ages $ 1$ Myr. We explored possible spatial correlations between stellar accretion rates in the Lupus star-forming region, which would support the hypothesis that infall can regulate stellar accretion. We considered both the `clustered' stars towards the centre of Lupus 3, and the `distributed' stars that are more sparsely distributed across the Lupus complex. We took the observed accretion rates in the literature and explore spatial correlations. In particular, we tested whether the clustered stars exhibit a radial gradient in normalised accretion rates, and whether the distributed stars have spatially correlated accretion rates. We found statistically significant correlations for both the clustered and distributed samples. The clustered sample exhibits higher accretion rates in the central region, consistent with the expected Bondi-Hoyle-Lyttleton accretion rate. Stars that are spatially closer among the distributed population also exhibit more similar accretion rates. These results cannot be explained by the stellar mass distribution for either sample. Age gradients are disfavoured, though not discounted because normalised disc dust masses are not spatially correlated across the region. Spatially correlated stellar accretion rates within the Lupus star-forming region argue in favour of an environmental influence on stellar accretion, possibly combined with internal processes in the inner disc. Refined age measurements and searches for evidence of infalling material are potential ways to further test this finding.

ZTF SN Ia DR2: Impact of the galaxy cluster environment on the stretch distribution of Type Ia supernovae

Understanding the impact of the astrophysical environment on Type Ia supernova (SN Ia) properties is crucial to minimize systematic uncertainties in cosmological analyses based on this probe. We investigate the dependence of the SN Ia SALT2.4 light-curve stretch on the distance from their nearest galaxy cluster to study the potential effect of the intracluster medium (ICM) environment on the intrinsic properties of SN Ia. We used the largest SN Ia sample to date and cross-matched it with existing X-ray, Sunyaev-Zel'dovich, and optical cluster catalogs in order to study the relation between the stretch and the distance to the nearest detected cluster from each SN Ia. We modeled the underlying stretch distribution with a Gaussian mixture with relative amplitudes that depended on redshift and clustercentric distance. We find that the fit quality of the stretch distribution improves significantly when we included the distance-dependant term in the model with a variation of the Akaike information criterion $ AIC = -10.2$. Because of the known correlation between galaxy age and distance from the cluster center, this supports previous evidence that the age of the stellar population is the underlying driver of the bimodal shape of the SN Ia stretch distribution. We further computed the evolution of the fraction of quenched galaxies as a function of distance with respect to cluster center from our best-fit model of the SNe Ia stretch distribution and compared it to previous results obtained from $H line measurements, optical broadband photometry, and simulations. We find our estimate to be compatible with these results. The results of this work indicate that SNe Ia searches at high redshift targeted toward clusters to maximize detection probability should be considered with caution as the stretch distribution of the detected sample would be strongly biased toward the old subpopulation of SNe Ia. Furthermore, the effect of the ICM environment on the SN Ia properties appears to be significant from the center of the clusters up to their splashback radius. This is compatible with previous works based on observations and simulations of a galaxy age gradient with respect to clustercentric distance in massive cluster halos. The next generation of large-area surveys will provide an increase of an order of magnitude in the size of SN Ia and cluster catalogs. This will enable us to analyze the impact of cluster mass on the intrinsic properties of SNe Ia and of the fraction of quenched galaxies in the outskirts of clusters in more detail, where direct measurements are challenging.

Calibrating and Standardizing the Tip of the Red Giant Branch in the Small Magellanic Cloud Using Small-amplitude Red Giants

We investigate the absolute calibration of the tip of the red giant branch (TRGB) in the Small Magellanic Cloud (SMC) using small amplitude red giant stars (SARGs) classified by the Optical Gravitational Lensing Experiment (OGLE). We show that all stars near the SMC’s TRGB are SARGs. Distinguishing older and younger RGs near the tip according to two period–luminosity sequences labeled A and B, we show many similarities among SARG populations of the Large Magellanic Cloud (LMC) and the SMC, along with notable differences. In particular, SMC SARGs have shorter periods due to lower metallicity and smaller amplitudes due to younger ages than LMC SARGs. We discover two period–color relations near the TRGB that span all A-sequence and B-sequence stars in the OGLE-III footprints of the SMC and LMC, and we investigate using periods instead of color for TRGB standardization. Using variability-derived information only, we trace the SMC’s age and metallicity gradients and show the core to be populated by younger, more metal-rich RGs. The B-sequence yields the brightest and most accurate calibration (M F814W,syn = −4.057 ± 0.019(stat.) ± 0.029(syst.) mag), which we use to measure the distance modulus difference between the Clouds and investigate metallicity effects. Distance measurements not informed by variability should employ the SARG-based calibration based on all stars near the tip (M F814W,syn = −4.024 ± 0.041(stat.) ± 0.029(syst.) mag). Our work highlights the impact of RG population diversity on TRGB distance measurements. Further study is needed to unravel these effects and improve TRGB standardization.

Assessment of Five-Year Relative Survival of Patients With Endometrial Cancer: A Period Analysis.

Endometrial cancer is one of the most common female cancers globally and in China. Although timely assessment of 5-year relative survival is crucial for guiding secondary prevention and early screening programs for endometrial cancer patients, those kinds of data are scarce in China. We aimed to provide a timely and accurate assessment of 5-year relative survival for patients with endometrial cancer from eastern China. Overall, 945 patients diagnosed with endometrial cancer during 2004 - 2018 from four cancer registries with high-quality data from Taizhou, eastern China were included. Period analysis was used to calculate 5-year relative survival for overall and the stratification by age at diagnosis and region. Model-based period analysis was used to predict the 5-year relative survival for the upcoming period of 2019 - 2023. We found that 5-year relative survival during 2014 - 2018 reached 86.4% for overall, while urban areas had higher survival compared to rural areas (91.3% vs. 85.3%). Furthermore, there was a clear age gradient, decreasing from 89.3% for age < 55 years to 80.5% for age > 74 years. Predicted 5-year relative survival for the upcoming period 2019 - 2023 could reach 88.4%. We provide, a timely and accurate assessment of 5-year relative survival for patients with endometrial cancer from Taizhou, eastern China, reaching 86.4% for overall. Our finding has important implications for the overall evaluation of early detection and screening programs for patients with endometrial cancer in eastern China.

Increasing Ages of Inga punctata Tree Soils Facilitate Greater Fungal Community Abundance and Successional Development, and Efficiency of Microbial Organic Carbon Utilization

Leguminous Inga trees are thought to enhance soil carbon (C) accumulation following reforestation, through mostly unknown mechanisms. This study amplified soil DNA using the ITS1F and ITS4 primers for PCR and Illumina MiSeq methods to identify fungal taxa, and traditional C analysis methods to evaluate how planted 4-, 8-, and 11-year-old Inga punctata trees affected soil fungal community compositions and C utilization patterns compared to old-growth I. punctata trees and an adjacent unplanted pasture within the same reforestation zone in Monteverde, Costa Rica. Along the tree age gradient, the planted I. punctata trees enhanced the tree soil C capture capacity, as indicated by increased levels of soil biomass C, Respiration, and efficiency of organic C use (with lower qCO2 values), and development of increasingly more abundant, stable, and successionally developed fungal communities, including those associated with the decomposition of complex organic C compounds. The level and strength of differences coincided with differences in the time of separation between the pasture and tree age or between the different tree ages. Fungal taxa were also identified as potential indicators of the early and late stages of soil recovery. Thus, planting I. punctata should be part of future reforestation strategies used in this region of the Monteverde Cloud Forest in Costa Rica.

Recognition and Characterization of Nanoscale Phases: Modulus Mapping of Asphalt Film in Pavement Mixture Cores.

The objective of this study is to recognize and characterize the nanoscale phase modulus mapping of the asphalt film in pavement mixture cores using atomic force microscopy quantitative nanomechanical technology. The pavement core samples from the upper and middle layers of four highways and laboratory samples were taken as the research object. The phase modulus-macro property correlation of recovered asphalt was analyzed using mathematical statistics. The results showed that the pavement core samples had more significant multi-phase and diversified phase characteristics compared to lab samples. This indicated that the asphalt in the pavement core had an obvious phase separation phenomenon due to aging. The phase modulus of each sample was distributed across a relatively wide numerical range, and there were also many numerical points with large fluctuations. Especially for the mixture sample containing SBS (Styrene-Butadiene-Styrene)-modified asphalt, the phase modulus distribution mappings presented a multi-peak phenomenon. Hence, considering the distribution characteristics of the data, the box plot method was introduced. Compared with quantified results from laboratory samples, the phase modulus of SBS-modified asphalt increased by 0.96 times, 1.18 times and 1.15 times, and that of base asphalt increased by 0.59 times, 0.56 times, 0.42 times, 1.24 times and 0.39 times, respectively. This indicates that the aging degree of asphalt in the upper layer was generally greater than that of the asphalt in the middle layer and that there was an aging gradient in the direction of pavement depth. All points were within the 95% confidence band in terms of correlation fitting, indicating a better fitting effect between phase modulus and complex shear modulus, as well as between phase modulus and penetration. This research provides innovative ideas for future multi-scale numerical simulation and cross-scale performance model development of asphalt binders.

GA-NIFS: the interplay between merger, star formation and chemical enrichment in MACS1149-JD1 at z=9.11 with JWST/NIRSpec

Abstract We present JWST/NIRSpec integral-field spectroscopy observations of the z ∼ 9.11 lensed galaxy MACS1149-JD1, as part of the GA-NIFS programme. The data was obtained with both the G395H grating (R∼ 2700) and the prism (R∼ 100). This target shows a main elongated UV-bright clump and a secondary component detected in continuum emission at a projected distance of 2 kpc. The R2700 data trace the ionised-gas morpho-kinematics in between the two components, showing an elongated emission mainly traced by [O iii] λ5007. We spatially resolve [O ii] λλ3726,3729, [O iii] λλ4959,5007, and [O iii] λ4363, which enable us to map the electron density (ne ∼ 1.0 × 103 cm−3), temperature (Te ∼ 1.6 × 104 K), and direct-method gas-phase metallicity (-1.2 to -0.7 dex solar). A spatially resolved full-spectrum modelling of the prism indicates a north-south gas metallicity and stellar age gradient between the two components. We found 3-σ evidence of a spatially resolved anti-correlation of the gas-phase metallicity and the star formation rate density, which is likely driven by gas inflows, enhancing the star formation in JD1. We employ high-z sensitive diagnostic diagrams to rule out the presence of a strong AGN in the main component. These findings show the unambiguous presence of two distinct stellar populations, with the majority of the mass ascribed to an old star formation burst, as suggested by previous works. We disfavour the possibility of a rotating-disc nature for MACS1149-JD1; we favour a merger event that has led to a recent burst of star formation in two separate regions, as supported by high values of [O iii] λ5007/Hβ, ionised gas velocity dispersion, and gas-phase metallicity.

Modeling and control strategy optimization of battery pack thermal management system considering aging and temperature inconsistency for fast charging

Maintaining the battery pack’s temperature in the desired range is crucial for fulfilling the thermal management requirements of a battery pack during fast charging. Furthermore, the temperature difference, temperature gradient, aging loss and energy consumption of the battery pack should be balanced to optimize its performance. This paper establishes the liquid cooling thermal management system model for an electric vehicle’s battery pack, which accurately characterizes the temperature distribution and electrical and aging characteristics of the battery pack. The discrepancies between the experimental and simulated results of battery’s fast charging-cooling suggest that maximum absolute temperature error is 2 °C, and the maximum relative voltage error is 1.5 %. Based on the non-dominated sorting genetic algorithm II algorithm, an optimization model with aging and temperature gradient of cells as objective functions is established. Three different thermal management strategies are created according to the optimization results. The comparison of these thermal management methods with the constant temperature cooling strategy demonstrates that the minimum temperature gradient strategy enhances the temperature consistency of the battery pack and reduces the maximum temperature gradient by 27 %. The minimum aging thermal management strategy depicts an aging loss of 0.091 %, reducing the charging time by 272 s and the maximum temperature gradient by 2.0 °C. The balanced thermal management strategy enables the battery pack to balance the temperature gradient and aging loss by optimizing the charging time, battery pack temperature difference, energy consumption and other indicators. The weight of each indicator is determined by its information entropy, which can be replaced according to the diverse needs to achieve different balanced thermal management strategies, providing a reference for the actual application of thermal management strategies.

Age-Related Blood Pressure Gradients Are Associated With Blood Pressure Control and Global Population Outcomes.

The strong relationship between blood pressure (BP) and age is well known. Limited evidence suggests that a steeper age-BP slope may be associated with an increased risk of adverse outcomes. The May Measurement Month campaign enables an investigation of geographic, socioeconomic, and sex differences in age-related BP gradients and their association with public-health outcomes. Cross-sectional, annual global BP May Measurement Month screening data were analyzed. Average systolic BP and age-related BP slopes across different age groups were calculated to assess regional, socioeconomic, and sex-stratified variations. The association of BP slopes derived from adjusted linear regression models with country-level health metrics was investigated. Age-related systolic BP gradients differed distinctly across global geographic regions, income levels, and between sexes. The steepest age gradients of BP were observed in populations from Africa and Europe. Women had lower BP levels than men at younger ages (20s and 30s) but subsequently experienced more pronounced age-related BP gradients. Geographically divergent age-related BP gradients were significantly associated with major national public health indicators. Globally, steeper age-related BP slopes were associated with poor BP control, increased disability-adjusted life years, and death rates. A steeper population age-BP slope of 1 mm Hg per 10 years was associated with a decrease in life expectancy of 3.3 years in this population (95% CI, -5.1 to -1.4; P=0.0007). Age-related BP gradients vary considerably across global populations and are associated with variability in BP-related risks and adverse outcomes across regions. Effective public health strategies may require region-specific targeting of adverse BP gradients to improve health outcomes.

Mismatches in Health: A Global Analysis of Discrepancies Between Self-Reported and Tested Mobility and Cognition

The health of individuals is frequently assessed based on self-reported information derived from surveys. However, self-reports are often inconsistent with their tested equivalents, indicating measurement issues. While discrepancies between self-reported and tested health indicators have been investigated for high-income countries in Europe, little comparative research has been conducted involving other low-income regions. This paper analyses discrepancies between self-reported and tested health limitations across 25 countries from six world regions with different income-levels, cultural backgrounds, institutional settings, and epidemiological trajectories. Using harmonised data from the Gateway to Global Aging, we match self-reported mobility and cognition with their tested equivalent to assess discrepancies at the individual level. Our results suggest that the consistency between these measures is strongly correlated with the Human Development Index, with lower scores of development showing higher discrepancies. Examining patterns by age reveals that self-reports do not accurately reflect the deterioration of health associated with aging – tested health exhibits a pronounced age gradient, whereas self-reported health varies little over the life course, particularly self-reported memory. We find no persistent gender differences in consistency. These discrepancies cast doubt on the reliability of mobility and cognitive self-reports, especially when comparing health across nations with differing development levels. * This article belongs to a special issue on “Levels and Trends of Health Expectancy: Understanding its Measurement and Estimation Sensitivity”.

Variations in plant–microbe–soil C:N:P stoichiometry along a 900-year age gradient in Torreya grandis ‘Merrillii’ plantations in Southeast China

Researches on the ecological stoichiometry of forest vegetation at different growth stages under long-term human management activities and its driving factors will help to clarify how the limited nutrient resources are allocated at different growth stages of forests, providing a basis and suggestions for scientific cultivation of artificial forests. In subtropical China, the C:N:P stoichiometry of an ancient Torreya grandis ‘Merrillii’ community was measured in leaves, twigs, roots, soils, and soil microbes with age gradients of 0–50, 50–100, 100–300, 300–500, and more than 500 years. The results showed that the nutrient use varied with tree ages. The N and P concentrations in the leaves, twigs, and roots of T. grandis had the similar increasing trends with the increasing tree age, and the N concentrations in leaves in 0-50-year-old forests were significantly lower than those forests of other ages. Particularly, the N:P ratio of different organs was always below 10, reflecting limited N supply of plants. The soil C content increased with the increasing T. grandis forest ages while the soil microbe C showed a fluctuated trend. There was a higher correlation among the C, N and P contents and their ratios in leaves, twigs and roots of 0-50-year-old forests than that in soil microbes, but inversely at more than 500-year-old forests. The homeostasis analysis results showed that the roots and soil microbes are more indicative of soil nutrient availability. The results of redundancy analysis showed that acid phosphatase activity had the highest impact on soil microbes in 0–10 and 10–20 cm soil layers, confirming that the decomposition and transformation of P in soils is very active. Moreover, soil enzyme activity mediates the influence of soil microbes on soil N and P limitation. In summary, tree age can effect the plant–microbe–soil C:N:P stoichiometry of T. grandis forests. The growth of T. grandis is mainly restricted by N, and reasonable application of N fertilizer is needed to promote its growth.

Age and metal gradients in massive quiescent galaxies at 0.6 ≲ z ≲ 1.0: implications for quenching and assembly histories

ABSTRACT We present spatially resolved, simple stellar population equivalent ages, stellar metallicities, and abundance ratios for 456 massive ($10.3\lesssim \log (\mathrm{M}_*/\mathrm{M}_\odot)\lesssim 11.8$) quiescent galaxies at $0.6\lesssim z\lesssim 1.0$ from the Large Early Galaxy Astrophysics Census, derived using full-spectrum models. Typically, we find flat age and [Mg/Fe] gradients, and negative [Fe/H] gradients, implying iron-rich cores. We also estimate intrinsic [Fe/H] gradients via forward modelling. We examine the observed gradients in three age bins. Younger quiescent galaxies typically have negative [Fe/H] gradients and positive age gradients, possibly indicating a recent central starburst. Additionally, this finding suggests that photometrically measured flat colour gradients in young quiescent galaxies are the result of the positive age and negative metallicity gradients cancelling each other. For older quiescent galaxies, the age gradients become flat and [Fe/H] gradients weaken, though remain negative. Thus, negative colour gradients at older ages are likely driven by metallicity gradients. The diminishing age gradient may result from the starburst fading. Furthermore, the persistence of the [Fe/H] gradients may suggest that the outskirts are simultaneously built up by mergers with lower metallicity satellites. On the other hand, the gradients could be inherited from the star-forming phase, in which case mergers may not be needed to explain our findings. This work illustrates the need for resolved spectroscopy, instead of just photometry, to measure stellar population gradients. Extending these measurements to higher redshift is imperative for understanding how stellar populations in quiescent galaxies are assembled over cosmic time.

Starspots and Undetected Binary Stars Have Distinct Signatures in Young Stellar Associations

Young stars form in associations, meaning that young stellar associations provide an ideal environment to measure the age of a nominally coeval population. Isochrone fitting, which is the typical method for measuring the age of a coeval population, can be impacted by observational biases that obscure the physical properties of a population. One feature in isochrone fits of star-forming regions is an apparent mass-dependent age gradient, where lower-mass stars appear systematically younger than higher-mass stars. Starspots and stellar multiplicity are proposed mechanisms for producing the mass-dependent age gradient, but the relative importance of starspots versus multiplicity remains unclear. We performed a synthetic red optical low-resolution spectroscopic survey of a simulated analog to a 10 Myr stellar association including mass-dependent multiplicity statistics and age-dependent starspot coverage fractions. We found that undetected starspots alone do not produce an apparent mass-dependent age gradient, but instead uniformly reduce the average measured age of the population. We also found that binaries continue to produce an apparent mass-dependent age gradient and introduce more scatter in the age measurement than spots, but are easily removed from the population as long as there are good distance measurements to each target. We conclude that it is crucial to incorporate treatments of both starspots and undetected stellar multiplicity into isochrone fits of young stellar associations to attain reliable ages.