This study explores the interaction between non-extensive entropic FLRW cosmology and the power-law inflationary model, with a focus on the overlap between the scalar spectral index “[Formula: see text]” and the tensor-to-scalar ratio “r”. Based on a conjecture that non-extensive entropy alters the energy–momentum content of the cosmic fluid, the analysis examines how these overlaps shift with different model parameters and compares the findings to those from Bekenstein–Hawking (BH) entropic cosmology. The study highlights the impact of Tsallis, Rényi, and Sharma–Mittal entropies, uncovering a significant correlation between “[Formula: see text]” and “r” that suggests a deeper connection in power-law inflationary dynamics. The results demonstrate that non-extensive entropies not only enable viable inflation with a graceful exit but also address limitations inherent in the standard BH entropic framework, emphasizing the importance of precise parameter estimation. Specifically, Tsallis entropy allows for power-law inflation with [Formula: see text] to [Formula: see text] in alignment with Planck 2018 data. Moreover, the [Formula: see text] parameter in Rényi and Sharma–Mittal entropy models must be extremely small ([Formula: see text] in Planck mass units) to achieve successful power-law inflation with an e-folding number around 55–65, suggesting a unified thermodynamic perspective in cosmological studies.