BackgroundSepsis is a life-threatening condition requiring urgent hospital treatment. The rates of recognition and doctors delay in primary care are currently unknown.AimTo explore the role of GP cooperatives in the pre-hospital care for sepsis patients.MethodA retrospective patient record study was conducted of sepsis patients admitted to an intensive care unit (ICU) in Ede, the Netherlands. Adult ICU patients admitted for community-onset sepsis between 2011 and 2015 were identified. Subsequently, all contacts with the co-located GP cooperative in the 72 hours before hospital admission were retrieved. Differences in mortality rates between subgroups were analysed using logistic regression analysis.ResultsOf 263 patients admitted to the ICU, 127 (48.3%) had prior GP cooperative contacts. These contacts concerned home visits (59.1%), clinic consultations (18.1%), direct ambulance deployment (12.6%) or telephone advice (10.2%). Patients assessed by a GP were referred in 64% after the first contact. The median delay to hospital arrival was 1.8 hours. In 43%, the GP had not suspected an infection. In this group the in-hospital mortality rate was significantly higher compared with patients with suspected infections (41.9% versus 17.6%). Mortality difference remained significant after correction for confounders.ConclusionGP cooperatives play an important role in pre-hospital management of sepsis and recognition of sepsis in this setting proved difficult. Efforts to improve management of sepsis in out-of-hours primary care should not be limited to patients with a suspected infection, but also include severely ill patients without clear signs of infection.
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