Good Mobility Research Articles

Correction of Severe Pterygium Colli with a Staged, Double, Posterior and Lateral Approach: A Case Report

AbstractPterygium colli is a rare congenital disorder characterized by excessive skin in the lateral and posterior neck, often associated with genetic syndromes such as Turner's syndrome or Klippel–Feil syndrome. Severe presentations present special challenges for surgeons since its diagnosis is not always evident and its treatment often results in important scaring. Surgical correction of the typical cases mostly involves a lateral approach, but in this “special” case, we used a double, posterior and lateral approach. A 15-month-old girl with prenatal diagnosis of a cystic lesion in the posterior neck presented with massive neck webbing at birth. Genetic studies ruled out chromosomal disorders and RASA 1 mutations. Surgical correction involved a modified posterior approach combined with a lateral approach 1 year later. The cervical tissue redundancy was successfully reduced achieving a good aesthetic outcome with very acceptable scars. At 1 year of follow-up, the patient continues with good neck appearance and mobility. The goal of surgical treatment of pterygium colli is achieving a harmonious neck contour with good function and minimal scarring while minimizing complications and sequelae. No consensus exists on the optimal approach for its correction, emphasizing the need for individualized treatment considering patient-specific characteristics, particularly in the severe cases.

Synthesis and carbon monoxide purification performance of ZSM-5 molecular sieve Co-doped Mn/V catalytic material

Trackless, rubber-tired, diesel-powered vehicles are widely used in the mining industry. In recent years, the use of high-performance catalysts to remove carbon monoxide (CO) from diesel vehicle exhaust has attracted much attention. In this paper, a series of manganese-vanadium doped ZSM-5 molecular sieve catalysts were prepared by an impregnation method. The structures of the catalysts were characterized and experiments were conducted to evaluate their performance. The CO catalytic oxidation performance experiments revealed that Mn0.6-V0.4-ZSM-5 had the best performance, with a conversion rate of 97.5 % at 300 °C. The catalyst was also tested for water resistance and stability. Kinetic measurements were performed and the fitted activation energy was 22.68 kJ/mol. Characterization studies revealed that the surface defects formed by Mn and V doping provided a large number of active sites and oxygen vacancies for CO oxidation, increased the number of adsorbed oxygen species on the surface, and enhanced the redox capacity through the interaction of Mn4+ and V5+ to improve the catalytic oxidation performance of the catalyst. The adsorption configurations, adsorption energy (Ebin), and formation energy of oxygen vacancies of CO at different adsorption sites and different active fractions were calculated with density functional theory. The Ebin of CO on Mn2V2O7, the active fraction of Mn0.6-V0.4-ZSM-5, was −1.29 eV, which was the most stable adsorption configuration. This configuration had good oxygen mobility, and was conducive to CO catalysis, confirming the characterization and performance experiments.

Clinical efficacy of arthroscopic single-bundle versus double-bundle reconstruction of the posterior cruciate ligament: a retrospective study.

To compare the functional and clinical outcomes of knee joints in patients over a 10-year period following posterior cruciate ligament (PCL) reconstruction with single-bundle versus double-bundle. Patients who underwent PCL reconstruction were retrospectively analyzed. Based on the surgical approach, they were divided into the single-bundle reconstruction group and the double-bundle reconstruction group. Preoperative and postoperative Lysholm score, International Knee Documentation Committee (IKCD) score, and Tegner activity score were evaluated, and the stability of the joints was assessed using KT-2000 arthrometer. Radiographs were taken at the final follow-up to evaluate the progression of osteoarthritis. A total of 61 patients were included in the analysis: 26 in the double-bundle group and 35 in the single-bundle group. Baseline data were comparable between the two groups (P > 0.05). There were no significant differences between the two groups in preoperative Lysholm, IKDC score, and Tegner activity score. Postoperatively, these scores were significantly higher at two and ten years follow-up (P < 0.05), with no significant difference between the groups (P > 0.05). There was no significant difference in side-to-side differences (SSD) at 30° and 90° of knee flexion preoperatively between the groups (P > 0.05). Postoperatively, SSD decreased significantly at the two year and ten year follow-up (P < 0.05), with no significant difference between the groups (P > 0.05). For osteoarthritis progression, there were four cases of Kellgren-Lawrence grade ≥ II in the single-bundle group and three cases in the double-bundle group, with no significant difference in the progression of osteoarthritis between the groups (P > 0.05). Both single-bundle and double-bundle reconstructions for PCL result in good joint stability and mobility, with similar progression of osteoarthritis in long-term follow-up. Level III.

Understanding the Factors Influencing Adoption of mHealth in Rural Patients: A Case of Embu, Kenya

Background and Purpose: Kenya and other low-income countries face healthcare challenges such as affordability, access, and health worker shortages. Digital technologies have disrupted traditional service delivery in industries such as banking and retail. Significant changes have not yet affected healthcare. Technological advancements in healthcare may help to leapfrog barriers such as the cost of physical infrastructure. The study examined the influence of technical, social, and individual factors in adopting mHealth products in Embu, Kenya. Methods: A cross-sectional quantitative study using a structured close-ended questionnaire was conducted in Embu, Kenya, between August and December 2019. Correlation and regression analysis were used to determine the effect of the influential factors on adopting mHealth products. Results: 207 (75%) randomly selected respondents over 18 years completed the survey, with the largest group (39.4%) aged between 35-44 years and 43% holding a post-secondary school diploma. Correlation analysis showed that social factors positively and significantly correlate to mHealth products' adoption (r (207) = .793, P &lt; .05), reflecting a generally favourable view towards using mobile phones for seeking healthcare. Similarly, technical factors showed a significant correlation with mHealth adoption (r (207) = .931, P &lt; .05), supported by widespread smartphone ownership and access to high-speed internet. Individual factors, including perceptions of the time-saving benefits of seeking healthcare services using a mobile phone, also demonstrated a positive correlation with the adoption of mHealth (r (207) = .708, P &lt; .05). Conclusions: Our study underscores the significant relationship of social, technical, and individual factors in adopting mHealth products. Digital health implementers should leverage increasing access to technical factors such as the Internet, smartphones, good mobile network coverage, and high utilization of social media to facilitate the positive adoption of mHealth. Our research provided insights from Embu; however, expansive studies encompassing rural and urban demographics are required to enhance generalizability

Primary and revision myringoplasty in children: Long-term outcome and analysis of the factors influencing the results

ObjectiveAssess the long-term outcome of pediatric myringoplasty. MethodsTympanoplasty type I, myringoplasty, was performed on 85 children (91 consecutive operations, 74 primary and 17 revisions) under 16 years of age. The perforations were sequela either to acute or chronic inflammatory middle ear disease. Medial grafting technique was employed with temporalis fascia. Adenoidectomy was performed earlier on all but five children. The preoperative observation period exceeded one year for all patients. The mean follow-up was 5.4 (SD 3.6) years. ResultsThe long-term graft take rate was 84% for primary myringoplasty, and 53% for revision operations. The re-perforations were associated with postoperative discharge, subtotal or total perforation and revision surgery. In the cohort, sixty ears (66%) were completely healthy (intact tympanic membrane in normal position without adhesions and with good mobility) after follow-up. Spontaneous healing took place in 37% after re-perforation. The preoperative ventilation tube treatment did not affect the outcome and there were no differences between age groups. Preoperative sonotubometry or Valsalva test results did not correlate with outcome. Four ears needed a ventilation tube during the follow-up due to poor ventilation. The mean pure tone thresholds improved significantly after operation. ConclusionsMyringoplasty in children is a reliable procedure without age restrictions. One year of preoperative observation excludes most unstable ears, and high tendency of spontaneous healing after re-perforation suggests the need for a lengthy follow-up before revision surgery.

A study on the high mobility and improved reliability of pr-doped indium zinc oxide thin film transistors

Abstract It is generally accepted that there is a trade-off relationship between mobility and stability for oxide thin film transistor (TFT) devices. Different doping ratios of Ln praseodymium (Pr) into indium (In) zinc (Zn) oxide have been employed as the active layer to get 1# and 2# amorphous oxide semiconductor (AOS) TFTs in this work. The 1#-based TFTs exhibited a high mobility of 49.84 cm2 V−1 s−1 due to the increased concentration of In. By further elevating the Pr doping ratio and adjusting In/Zn ratio of the film, the 2#-based TFT obtained both a good mobility of 26.65 cm2 V−1 s−1, and a promising stability, showing a positive-bias temperature stress stability of ΔV TH = 1.56 V and a negative-bias temperature illumination stress stability of ΔV TH = −1.47 V. It was revealed that the low energy charge transfer state of Pr in 2# film absorbs the visible light, leading to suppressed photo-induced carriers and thus a good illumination reliability of the 2#-based TFTs. In practice, the LCD panel based 2# ACT TFT shows a well stable performance even under 10 000-nit illumination. The result indicates a promising strategy to accelerate the commercialization of AOS TFTs to large-panel display production.

A case of early-onset congenital syphilitic osteomyelitis of the calcaneus and literature review

BackgroundCongenital syphilis (CS) is a sexually transmitted disease caused by Treponema pallidum (TP). When the skeletal system is involved, it often results in multiple, symmetrical bone destruction at the epiphyses of long tubular bones such as the humerus and radius, rarely involving the calcaneus. This article reports a case of calcaneal osteomyelitis caused by TP in a child with no other bone damage and subtle clinical manifestations, No similar cases have been reported.Case presentationA 4-month-old male infant presented with right foot swelling without any obvious cause and no history of trauma. X-ray and CT scans showed bone loss in the calcaneus and surrounding soft tissue swelling. Review of past medical records revealed that the infant had been diagnosed with CS infection during a hospital stay for “pneumonia” at one month old. The parents refused surgery, opting for conservative treatment at an external hospital for three weeks, during which the symptoms of the affected foot showed no significant improvement. Subsequently, the child was treated at our hospital with surgery, including lesion removal and cast fixation, followed by oral antibiotic treatment. The last follow-up showed no swelling or tenderness in the affected foot, with good mobility, and X-rays indicated that the bone had essentially returned to normal.ConclusionsEarly CS rarely involves the calcaneus. When diagnosing unexplained calcaneal osteomyelitis in infants, this rare cause should be considered. A thorough medical history should be taken and a careful physical examination conducted. Once diagnosed, timely surgical debridement and appropriate antibiotic therapy targeting TP infection are required. Early identification and intervention can result in a good prognosis without related complications.

Batik Scan: Empowering Cultural Heritage Knowledge Through Mobile Innovation

Batik Malaysia, a type of textile art known as Batik originated in Malaysia, especially in the east coast states; Kelantan, Terengganu, and Pahang. The Batik mostly uses features flower motifs and designs instead of living creatures, such as humans and animals. Even though Malaysian wear it every day, they do not have sufficient knowledge about Batik. Besides, there is a limited number of platforms where Malaysian can get access to the information of Batik in the easiest and fastest way. Hence, this study aims to design and develop a mobile app for batik identification by only capturing the motifs and designs using a camera feature. The app, called as batik scanner, provides quick information related to Batik Malaysia. This app is especially suitable for adults, batik lovers, and new learners. The advances in digital technology play an important role in helping people to identify the type of Batik Malaysia. It also can reduce the effort of new learners and Batik lovers to find out information of Batik. To ensure that users will have a good mobile user experience, an understanding of the importance and limitation of the mobile app features and behaviour is necessary. Therefore, the design thinking approach was applied as the development methodology as it provides a solution-based approach to solving problems. User requirements were gathered through interviews followed by defining the core problems. Next, innovative solutions were identified using the brainstorm technique and mind mapping. Once the batik scanner prototype was completed, user testing was carried out with the targeted respondents to refine the solution. An online form also was distributed to evaluate the usability of the prototype. The results of the evaluation indicate that the Batik Scanner need to improve some of the interface designs. The respondents were also satisfied with the functions of managing the information in the Batik Scanner. The study contributes toward understanding users’ needs in creating the solution to the identified problems. It may serve as a guideline for other developers and researchers to develop similar apps or to enhance the features of Batik Scanner to become better and easier for users.

Unveiling Strong Thin Film Confinement Effects on Semirigid Conjugated Polymers.

Nanoconfinement has been recognized to induce significant changes in the physical properties of polymeric films when their thickness is less than 100 nm. Despite extensive research on the effect of nanoconfinement on nonconjugated polymers, studies focusing on the confinement effects on dynamics and associated electronic and mechanical properties for semiconductive and semirigid conjugated polymers remain limited. In this study, we conducted a comprehensive investigation into the nanoconfinement effects on both p- and n-type conjugated polymers having varying chain rigidity under different degrees of confinement. Using the flash differential scanning calorimetry technique, it was found that the increased molecular mobility with decreasing film thickness, as indicated by the depression of glass transition temperature (T g) from its bulk values, was directly proportional to chain rigidity. This relationship between chain rigidity and enhanced segmental mobility was further corroborated through molecular dynamics simulations. Thinner films exhibited a higher degree of crystallinity for all conjugated polymers, and a significant reduction of more than 50% in elastic modulus was observed for films with approximately 20 nm thickness compared to those of 105 nm thickness, particularly for highly rigid conjugated polymers. Interestingly, we found that the charge mobility remained independent of film thickness, with all samples demonstrating good charge mobility regardless of the different film thicknesses for devices measured here. Nanoconfined conjugated polymer thin films exhibited a combination of mechanical compliance and good charge carrier mobility properties, making them promising candidates for the next generation of flexible and portable organic electronics. From an engineering standpoint, confinement could be an effective strategy to tailor the dynamics and mechanical properties without significant loss of electronic property.

Flame aerosol deposition Y3Al5O12:Yb 3+ , Er 3+ nanoparticles on monolayer MoS2 for broadening near-infrared photoelectroresponse

Monolayer molybdenum disulfide (MoS2) is a two-dimensional material with a direct bandgap widely used in photoelectric detection. It exhibits excellent characteristics such as an ultra- high specific surface area, strong light interaction, and good carrier mobility. However, due to the bandgap limitation, monolayer MoS2 can only efficiently detect visible wavelengths less than 680 Combining lanthanide-doped upconversion nanoparticles with monolayer MoS2 to realize near- infrared (NIR) photodetection is a feasible strategy. Thus, Y3Al5O12:Yb 3+ , Er3+ up-conversion nanoparticles are deposited on the surface of a monolayer MoS2 by flame aerosol deposition (FAD), significantly extending their photoelectric response range to the near-infrared 980 nm. The Y3Al5O12:Yb 3+ , Er3+ nanoparticles synthesized by flame can achieve efficient up-conversion from near-infrared (~980 nm) to visible light (~450, ~550, ~650 nm). Therefore, the visible light can be subsequently absorbed by monolayer MoS2. The carefully designed Y3Al5O12:Yb 3+ , Er3+ /MoS2 photodetector shows strong responsivity and highly specific detectivity in the near-infrared spectrum. Under the bias voltage of 3 V and laser irradiation of 980 nm at 2.8 μW, the newly designed MoS2 device achieves a responsivity of 16.82 A/W and a specific detectivity of 1.47×10 12 Jones, as the traditional monolayer MoS2 usually responds to zero. This work can further expand the application of two-dimensional materials and their composites in near-infrared photoelectric detection

Preemptive Approach to Plerixafor Use Is Optimal in Patients With Relapsed/Refractory Germ Cell Tumors Undergoing Peripheral Blood Hematopoietic Stem Cell Collection: Effect on Collection Days, Yields, and Cost.

Evidence describing the use of plerixafor in the off-label population of relapsed/refractory germ cell tumors (GCT) is limited. Weaim to describe the effect of rescue versus preemptive plerixafor use on apheresis collection days, collection yields, and cost. We retrospectively collected data on 77 consecutive patients (at least 15 years of age) with GCT who underwent peripheral blood stem cell (PBSC) collection for autologous stem cell transplant between January 1, 2020 and May 1, 2022. Depending on insurance approval, plerixafor was given either as "rescue" (after a first apheresis collection of < 5 × 106 CD34+ cells/kg) or as "preemptive" on Day 4 of granulocyte-colony stimulating factor (G-CSF) prior to the first apheresis collection, if the Day 4 peripheral blood CD34+ count was < 40 cells/μL. A total of 66% of patients who received preemptive plerixafor completed collection in 1 day, similar to good mobilizers who only needed G-CSF (71%, p = 0.366). In contrast, all poor mobilizers in the rescue group required at least 2 days of collection and had lower CD34+ cell yields than the preemptive group (7.15 vs. 9.81 × 106/kg, p = 0.0055). A cost analysis revealed that preemptive plerixafor may save approximately $7000 per patient compared with a rescue approach. Preemptive plerixafor in GCT patients undergoing PBSC collection allows relatively poor mobilizers to collect in fewer days and with lower overall cost. Fewer apheresis procedures result in less risk to the patient, increased patient satisfaction, and the ability to schedule more patients within the constraints of staffing.

Digital Health: The Critical Value of Mobile Technology for the Health Sector, Different Application Examples from the World and Current Trends

The internet technology, which began to integrate into our lives rapidly by the end of the 1990s, underwent significant transformations with the advent of mobile technology in the 2000s. Initially accessible through desktop or notebook computers, the internet has evolved to become an integral part of virtually every aspect of our lives as mobile technology advanced throughout the 2000s. The purpose of this study is to examine the role of mobile technologies within current health technologies, investigate the necessary competencies, evaluate mobile technology developments both in Türkiye and globally, and assess the information technology infrastructure, competencies, and skills required by the sector. Our research details various and specific mobile applications from numerous countries. Findings indicate that mobile technology has established itself much more rapidly and effectively in countries with strong internet infrastructure. Mobile health services are perceived as highly valuable by citizens. The real quality and effectiveness of mobile technology depend on its acceptance and swift implementation by users. Gamification is an important tool in the adoption of mobile health applications. These applications can enhance motivation by enabling both doctors to monitor patient care services and patients to track their own health. A good mobile health system should be accepted by both patients and doctors. In countries like Türkiye, where the health system is largely supported by the state, it is seen as necessary for the Ministry of Health to prioritize mobile services to establish a robust mobile health system. Furthermore, to effectively structure mobile services, it is essential to focus on the right problems and identify issues in order of priority. Literature review reveals that various mobile applications have been implemented in fields such as dermatology, orthopedics, ophthalmology, neurosurgery, and clinical pathology. Mobile technologies offer significant cost advantages in the delivery of health services. As the population ages in European Union countries, national governments are seeking ways to reduce healthcare costs. Mobile health is considered a solution to transform the delivery of health services and reduce costs through viable new care models for both industrialized and developing countries. Moreover, it has been observed that mobile applications provide significant benefits for the elderly, particularly in developed countries such as Germany and Sweden. Our study provides a comprehensive assessment of mobile technology in the healthcare sector, highlights prominent applications from Türkiye and around the world, and offers an extensive evaluation for field readers.

Unveiling the optoelectronic features and physical stability of novel Cs2HgPdI6: Computational insights

In recent years, researchers have been devoted to search for novel stable halide perovskite materials with outstanding photovoltaic performance. Herein, through density functional theory (DFT) calculations, we uncover for the first time the crystal stability, structural parameters, optoelectronic features, and photovolatic performance of Cs2HgPdI6. The Jahn−Teller-distorted Cs2HgPdI6 is detected by its structural feature. The stability of novel Cs2HgPdI6 is completely ensured by means of the DFT calculations. Accurate electronic structure calculations show that Cs2HgPdI6 exhibits an appropriate fundamental gap (1.278 eV). This band gap is mainly determined by the interaction between the I-5p and Pd-4d orbitals. Additionally, Cs2HgPdI6 has good carrier mobility and an ultra-low exciton binding energy. Meanwhile, it also exhibits relatively weak anisotropic optical properties and strong visible-light absorption. The large theoretical conversion efficiency of 31.7 % is illustrated for Cs2HgPdI6. Overall, our research highlights the great potential of this novel compound for photovoltaic applications.

805. BOCHDALEK HERNIA - CASE REPORT

Abstract Introduction Bochdalek hernia is a rare type of diaphragmatic hernia congenital and is quite uncommon in adulthood, representing only 0.17-6% of all diaphragmatic hernias. The objective of the present study is to report the technique surgery performed on a patient with a bochdalek hernia. Methods The information was obtained through medical record review, interview with the patient and literature review. Results/Discussion A 49-year-old female patient was admitted to a hospital in Natal (RN- Brazil) with vomiting for seven months, average of 3-4 vomits daily after meals, associated with dysphagia, epigastric pain and weight loss of 26 kg during this period. The physical examination, she was dehydrated, emaciated and with a flaccid abdomen and painless. Laboratory exams, she presented high levels of ureia and hypokalemia. CT scan of the chest and abdomen with contrast showed a hernia right posterolateral diaphragm with insinuation of the transverse colon and portion distal part of the stomach, in addition to significant gastric stasis, without signs of ischemia. Vigorous hydration was carried out and fasting was maintained, in addition, was inserted nasogastric tube and began parenteral nutrition. After ten days of parenteral nutrition and correction of hydro electrolyte disorders, there was an improvement in symptoms with laboratory normalization. So, she undergo a surgical intervention by videolaparoscopy. Surgical intervention took place with the pneumoperitoneum with Veress needle and trocars inserted (2 10-inch trocars). mm and 3 of 5 mm). Introduction of 30° optics. Cavity inventory identified massive right posterolateral diaphragmatic hernia, containing transverse colon and part of the stomach. Hepatic retractor was positioned to retracted the right hepatic lobe. Completely reduced the hernia through the Bochdalek foramen, after undoing content adhesions with the diaphragm. Afterwards, the closing of the defect with 2-0 Ethibond thread and a biocompatible mesh placed over the suture (Phasix) 10x10 cm and fixed with the same thread in separate stitches. Left drain blake type number 24 Fr, was left in the right hemithorax. The procedure was done uneventful. Conclusions Bochdalek hernia is a structural defect in the diaphragm, which can cause the passage of practically any intra-abdominal organ to the chest. Surgical repair of the defect is the only existing treatment option. In this case, we have a late presentation and in a complicated form. We opted for clinical stabilization of the patient, with nutrition and timely videolaparoscopy on the tenth day of hospitalization. The correction of hernia laparoscopically allows wide access to the workplace and with good mobility for dissection of the hernial sac, in addition to unquestionable acceleration of postoperative recovery and reduction of surgical trauma and size of the incisions. This way, we have a shorter hospitalization time with early return to the patient's daily activities.

Visa-on-arrival, ECOWAS-free Mobility and the Securitisation of the Intra-African Migration in Nigeria

Over the years, Nigeria’s regional hegemonic leadership in (West) Africa, especially within the Economic Community of West African States (ECOWAS) region, has been debated within academic and foreign relations circles. A major component of this regional leadership aspiration was its quest for a ‘borderless Africa’. As an important arrowhead of its pro-African foreign policy, the Nigerian government proactively crafted a benign national border policy to give practical expression to the free mobility of persons and goods within the West African subregion. Despite a demonstrable commitment to free mobility within Africa over the years, Abuja suddenly imposed a restrictive border policy shortly after it signed the African Continental Free Trade Area (AfCFTA) agreement and approved the contentious visa-on-arrival for African migrants. Considering this context, this study makes three arguments: First, it interrogates the rationale behind the liberal border diplomacy of the Nigerian government. Secondly, the paper contends that the inability to ‘silence the guns’ in Africa despite all efforts has seriously militated against the aspiration for intra-African mobility and borderless Community in West Africa. Lastly, the study examines the dire implications of Nigerian nationalistic border diplomacy and its declining soft power for the future of ‘borderless West Africa’.

All-2D CVD-grown semiconductor field-effect transistors with van der Waals graphene contacts

Two-dimensional (2D) semiconductors and van der Waals (vdW) heterostructures with graphene have generated enormous interest for future electronic, optoelectronic, and energy-harvesting applications. The electronic transport properties and correlations of such hybrid devices strongly depend on the quality of the materials via chemical vapor deposition (CVD) process, their interfaces and contact properties. However, detailed electronic transport and correlation properties of the 2D semiconductor field-effect transistor (FET) with vdW graphene contacts for understanding mobility limiting factors and metal-insulator transition properties are not explored. Here, we investigate electronic transport in scalable all-2D CVD-grown molybdenum disulfide (MoS2) FET with graphene contacts. The Fermi level of graphene can be readily tuned by a gate voltage to enable a nearly perfect band alignment and, hence, a reduced and tunable Schottky barrier at the contact with good field-effect channel mobility. Detailed temperature-dependent transport measurements show dominant phonon/impurity scattering as a mobility limiting mechanisms and a gate-and bias-induced metal-insulator transition in different temperature ranges, which is explained in light of the variable-range hopping transport. These studies in such scalable all-2D semiconductor heterostructure FETs will be useful for future electronic and optoelectronic devices for a broad range of applications.

Assessment of Health-Related Quality of Life and Its Determinants in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study.

Background Type 2 diabetes mellitus is a complex metabolic disorder associated with several complications that determine the quality of life of the patients. Health-related quality of life (HRQoL) is a measurable outcome of the self-perception of a patient's health which is affected due to age, lifestyle changes, medication, and treatment modalities. This study was undertaken to understand the impact of individual parameters of age, medication type and duration, diabetes-associated complications, and levels of glycated hemoglobin (HbA1c) on the quality of life (QoL) of the patient. Methodology This single-center prospective, cross-sectional study was conducted at the Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, Bihar, India. Participants were recruited from the Outpatient Department of General Medicine, IGIMS.HRQoL was measured using a validated and reliable EuroQol 5-dimensions 5-levels (EQ-5D-5L) questionnaire developed by the EuroQol Research Foundation, along with the EuroQol-Visual Analogue Scale (EQ-VAS). The eligibility criteria included adult diabetic patients above 18 years of age with complete medical records, who had been treated at the outpatient department for a minimum of three months and could be interviewed. Results The results from this study show that 46% of the patients belonged to the age group of 45-65 years. The quality of health index scores and EQ-VAS scores significantly correlated withage (p-values: 1.11 e-4 and 3.09 e-5; <0.05). Of the subjects,66.4%, 6.7%, and 26.8% were under oral hypoglycaemic agents (OHA), insulin, and both insulin with OHA medications respectively. HbA1C levels werestatistically significantly correlated with mobility, self-care, usual activities, pain or discomfort, and anxiety or depression (p-value 0.032; <0.05), along with self-perception of the patient's health (p-value 0.00026; <0.05).Also, the perception of having slight problems in mobility, self-care, usual activities, pain or discomfort, and anxiety or depression was similar irrespective of gender (EQ-5D-5L score for males: 9.47 and females: 9.3). Despite suffering from diabetes-associated chronic complications, 60.5% of the subjects perceived their overall health to be good as indicated by the scores. Conclusion The self-perception of HRQoL concerning mobility, self-care, usual activities, pain or discomfort, and anxiety or depression was correlated with age, duration of anti-diabetic medication, and HbA1C level. Good mobility, self-care, and performing usual activities reduce anxiety or depression as opposed to age, pain, and discomfort. However, the subjects in this study cohort perceived overall good health in themselves in terms of EQ-VAS and 5D-5L scores, indicating effective diabetic care and management options available to them.

PERAN PROFITABILITAS DALAM MEMODERASI PENGARUH FIRM SIZE DAN LEVERAGE TERHADAP NILAI PERUSAHAAN PADA PERUSAHAAN TRANSPORTASI DAN LOGISTIK YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2019-2022

Indonesia has entered the era of the industrial revolution 4.0 which is clearly visible with an increase in connectivity, interactivity, and boundaries between humans, machines, and resources on information technology and other communications. Judging from the current business world on the aspect of competition, the Indonesian economy is increasingly experiencing major developments. The transportation and logistics sector has an important role in people's lives driven by the increasing needs of the community for mobility and transportation of goods to all regions. Despite the ongoing economic crisis, transportation services will continue to operate smoothly because people will continue to use them to send goods from producers to consumers, regardless of the conditions in which they work. The purpose of this study was to analyze and test the role of Profitability in Moderating the effect of Firm size and Leverage on Firm value. The population in this study were transportation and logistics companies with 37 companies listed consecutively on the Indonesia Stock Exchange during 2019-2022. The sampling technique was determined by purposive sampling. Data analysis and hypothesis testing using Structural Equation Analysis - Partial Least Square (PLS-SEM). The results of research hypothesis testing using the Smart PLS 3.0 application, show that Firm size has a significant negative effect on firm value, Leverage has a significant positive effect on firm value, Profitability does not significantly moderate the effect of Firm size on firm value, Profitability does not significantly moderate the effect of Leverage on firm value.

Conjugation-Broken Dimer Acceptors Enable High-Efficiency, Stable, and Flexibility-Robust Organic Solar Cells.

Dimer acceptors in organic solar cells (OSCs) offer distinct advantages, including a well-defined molecular structure and excellent batch-to-batch reproducibility. Their high glass transition temperature (Tg) aids in achieving an optimal kinetic morphology, thereby enhancing device stability. Currently, most of dimer acceptor materials are linked with conjugated units in order to obtain high power conversion efficiencies (PCEs). In this study, different from previous works on conjugation-linked dimer acceptors, a novel series of dimer acceptors are synthesized (named T1, T4, T6, and T12), each linked with different flexible alkyl linkers, and investigated their PCEs, device stability, and flexibility robustness. When blended with PM6, the T6-based device achieves a PCE of 17.09%, comparable to the fully conjugated T0-based device's PCE of 17.12%. The molecular dynamics simulations anddensity functional theorycalculations suggested that flexible conjugation-broken linkers (FCBLs) promote intermolecular electronic couplings, thereby maintaining good electron mobilities of dimer acceptors. Notably, the T6-based device exhibits impressive long-term stability with a T80 lifetime of 1427h, while in the T0-based device, T80 is only 350h. The present work has thus established the relationship between the length of flexible alkyl linkers in such dimer acceptors and the performance and stability of OSCs, which is important to further designing new materials for the fabrication of efficient and stable OSCs.

Electronic, Transport, and Optical Properties of Potential Transparent Conductive Material Rb2Pb2O3

To better verify the potential of Rb2Pb2O3 as p‐type transparent conductive oxides (TCOs), the structural, electronic, mechanical, transport, and optical properties of Rb2Pb2O3 are calculated in detail under the framework of density functional theory. Significantly, Rb2Pb2O3 is a p‐type semiconductor with an indirect 2.82 eV bandgap. Herein, the Pb‐6p and O‐2p orbits hybridized to form ionic PbO bonds, which determines the degree of localization of electrons in valence band maximum. Interestingly, the RbO bond is extremely weak, and the Rb atom is rarely involved in bonding interactions. This contributes to isotropy, ductility, and good mobility of Rb2Pb2O3, making it soft and suitable for application in flexible electronics. More importantly, as a transparent conductive material, Rb2Pb2O3 not only shows good transparency in the visible region but also has good electrical conductivity. Therefore, Rb2Pb2O3 as an intrinsic p‐TCO with good performance is preliminarily identified. The theoretical finding provides a new candidate for p‐TCOs and paves the way for further performance improvement of Rb2Pb2O3.