<h3>Research Objectives</h3> To investigate the validity and reliability of the PostureRite system as a dynamic postural instability measurement device in children with CP, as well as the link between the PostureRite and traditional clinical measures, including the GMFM, PBS, and FES. <h3>Design</h3> Randomized Controlled Trial. <h3>Setting</h3> The first study was performed in the motion analysis laboratory to determine the concurrent validity of new accelerometers compared to the Vernier. The second study was in a local community rehabilitation center to determine the reliability and sensitivity of the PostureRite for healthy adults and children with CP. <h3>Participants</h3> 11 healthy young adults and 10 children with CP were recruited from a major university and local community rehabilitation center. <h3>Interventions</h3> The DPI measurement was the body sway with an accelerometer device (X, Y, and Z-axis), performed in the highest GMFM level possible. All participants had familiarizing period with the crawling and gait movement before actual data collection. For performing the standardized gait movement consistently, all participants were instructed to walk 7m back and forth three times at the preferred speed. <h3>Main Outcome Measures</h3> 3-axis body sway measures were recorded by the PostureRite and Vernier, as well as GMFM, PBS, and FES to identify the connection between the accelerometer and the traditional clinical measure score. <h3>Results</h3> The concurrent validity analysis showed a relationship between the Vernier and PostureRite, P<0.05. The test-retest reliability demonstrated a good relationship across the three repeated measures of the DPI data, P<0.05. The PostureRite sensitivity analysis revealed a significant discriminability in DPI data between the healthy and individuals with CP (P<0.05). GMFM and PBS scores were inversely correlated with the X-axis (P<0.05). The correlation of FES scores and the X-axis was moderate (P<0.05). <h3>Conclusions</h3> This study shows promise as a robust and reliable technique for assessing a wide variety of gait parameters in children with cerebral palsy. In a variety of situations, including outcome and screening studies, this device can be utilized in conjunction with clinical balance and mobility assessments. <h3>Author(s) Disclosures</h3> The authors report no conflict of interest.