Globular Profiles Research Articles

Una vasija decorada ibérica de función ceremonial: un espacio singular en el Coll del Moro (Gandesa, Tarragona).

Se presenta un vaso ibérico del siglo III ane excepcionalmente decorado procedente del ámbito 8 del poblado del Coll del Moro de Gandesa (Tarragona). Se trata de una marmita cerámica de cierre hermético, elaborada a mano, de perfil globular, con dos asas horizontales torsionadas y profusa decoración geométrica y zoomorfa. Presenta un asa de pomo, maciza, subcuadrangular, que está decorada en cada uno de sus cuatro ángulos superiores con motivos plásticos, sendas cabezas de carnero estilizadas. El fondo interno de la vasija está decorado con una cruz esvástica en altorrelieve. Tanto el carnero como la cruz, los dos elementos decorativos más sobresalientes de la pieza, tienen un arraigado simbolismo relacionado con el culto al hogar y a los antepasados. La función de la vasija es, sin lugar a dudas, ritual. Entronca con cultos al hogar y a los antepasados ya atestiguados en la protohistoria de la Península Ibérica y pone de manifiesto que en el ámbito en el que se hallaba se desarrollaban ceremonias de culto. Dicho ámbito se ubica en lo que podemos llamar un barrio productivo o industrial del asentamiento donde se ha exhumado un conjunto arquitectónico dedicado al enriado del lino y a otras actividades textiles y otro dedicado a lagar y almacenaje de vino. El hallazgo aporta nuevas perspectivas sobre las actividades ceremoniales y el mobiliario de culto en el nordeste peninsular, tan avaro respecto a este tipo de información.

Fine structure of the monkey epididymis: A correlated thin-section and freeze-cleave study

The epithelium of the monkey epididymis was studied by means of freeze-fracture techniques and conventional electron microscopy. For the study of transepithelial permeability lanthanum hydroxide was used as an intercellular tracer. The epididymal epithelium consists mainly of tall columnar cells. The long stereocilia at the apical surface, similarly to microvilli, exhibit after freeze-fracture, two distinct faces: the E face, concave and with fewer membrane-associated particles, and the complementary convex P face. In the lumen unusual groups of smooth-surfaced vacuoles are present. A tight junctional network, which shows some permeability to the lanthanum tracer, is located at the apical end of the cells. Supranuclear cross-fractures clearly show the well developed Golgi cisternae and numerous vacuole profiles. The highly infolded, centrally located nucleus exhibits, after freeze-fracture, an even distribution of nuclear pores. In the perinuclear region the rough endoplasmic reticulum, which also presents pores, displays a sheet-like organization. The basal cytoplasm is filled by numerous globular profiles of membrane-bounded granules. Freeze-cleave exposes large cytoplasmic areas where the types and amount of organelles indicate an intense metabolic activity.

A study of light and scanning electron microscopy of the lining epithelium of the guinea pig bladder following artificial ulceration.

Following artificial ulceration of the guinea pig bladder epithelium, study by light microscopy showed that mitotic activity occurs within 24 hours in the basal layer of the remaining epithelium; which leads to thickening, disorganization and cell shedding. At the ulcer margin, the epithelium forms a rolled edge, from the extremity of which a two-layered sheet of flat cells grows over the edematous ulcer bed, and the ulcer site is protected during dilation of the bladder by localized muscle spasm. Healing is effected within about one week, as the mitotic activity declines. Organization of the new epithelium commences at the periphery and the cells acquire glycogen and alkaline phosphatase. Study by SEM, which included normal bladders, confirmed that new epithelium spreads from a rolled epithelial edge, and also showed that cells undergoing rejection have globular profiles with surface microvilli. The immature epithelial cells are markedly distorted from mutual pressure during migration and their surfaces show only short microvilli. Ulcers heal after four to seven days, depending on size, and the new cells rapidly assume the pentagonal and hexagonal outlines and the reticular pattern of surface ridges, characteristic of mature surface cells. The ridges apparently develop by fusion of rows of microvilli. By the tenth day it is difficult to identify the original ulcer site.

PATHOLOGICAL STUDY ON AMYLOIDOSIS – THE FINE STRUCTURE OF AMYLOID‐LADEN LIVER AS REVEALED BY FREEZE‐ETCHING

Amyloid in freeze-etched specimen of liver of mice receiving subcutaneous in sodium caseinate was studied morphologically. The convex surface and cross surface of amyloid nodule were noted. The three dimentional structure of the amyloid fibrils which showed felt-like structure, globular profiles among amyloid fibrils and amyloid bundles were clearly visible. Amyloid bundles enveloped by the cytoplasmic membrane of the Kupffer cell projected from the deeply concave surface of the cytoplasmic membrane into the Disse's space and showed the appearance of ston-column-like structure. The amyloid bundles projecting from the invaginated cytoplasmic membrane were closely in contact with the cytoplasmic membrane and deeply rooted in the cytoplasm of the Kupffer cell.