Global Research Research Articles

A Collaborative Code Platform with Advanced AI Features and Real-Time Collaboration Tools

Abstract: Good collaboration and code management are crucial in today's software development environment. Our research has launched a new collaborative process that combines AI resources, including AI and global research, to improve products and enhance and facilitate collaboration. The platform features real-time collaboration tools such as dynamic text with multilanguage support, dialog functionality, and notepad functionality. With OAuth authentication, users can seamlessly perform CRUD operations on files and directories, share code repositories, and participate in live coding sessions. The platform supports compilation and execution of a code file and follows good design principles such as caching, microservices architecture, and containerization to ensure scalability and performance. The platform focuses on user experience by providing simple user interface design and easy interface navigation. Users can create workspaces, share them collaboratively, and seamlessly import repositories from Git. The platform's intelligent data manager helps manage files and directories, while the collaborative platform allows developers to collaborate on code libraries efficiently. The platform is modern web-based, using React on the frontend and Node.js on the backend; Supported with syntax highlighting and smart initialization along with Socket.io for runtime with SQL and NoSQL databases. Provides comprehensive language support. All progress is saved, providing users with peace of mind. While the basic design is for desktops, future iterations are expected to support mobile devices.

Abstracts of the papers presented in the international conference of Indian Virological Society, VIROCON 2023 on “Advancements in global virus research towards one health” held during 01–03 December, 2023 at ICAR-National Research Centre for Banana, Tiruchirappalli, Tamil Nadu, India

Abstracts of the papers presented in the international conference of Indian Virological Society, VIROCON 2023 on “Advancements in global virus research towards one health” held during 01–03 December, 2023 at ICAR-National Research Centre for Banana, Tiruchirappalli, Tamil Nadu, India

The Galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update.

Galaxy (https://galaxyproject.org) is deployed globally, predominantly through free-to-use services, supporting user-driven research that broadens in scope each year. Users are attracted to public Galaxy services by platform stability, tool and reference dataset diversity, training, supportand integration, which enables complex, reproducible, shareable data analysis. Applying the principles of user experience design (UXD), has driven improvements in accessibility, tool discoverability through Galaxy Labs/subdomains, and a redesigned Galaxy ToolShed. Galaxy tool capabilities are progressing in two strategic directions: integrating general purpose graphical processing units (GPGPU) access for cutting-edge methods, and licensed tool support. Engagement with global research consortia is being increased by developing more workflows in Galaxy and by resourcing the public Galaxy services to run them. The Galaxy Training Network (GTN) portfolio has grown in both size, and accessibility, through learning paths and direct integration with Galaxy tools that feature in training courses. Code development continues in line with the Galaxy Project roadmap, with improvements to job scheduling and the user interface. Environmental impact assessment is also helping engage users and developers, reminding them of their role in sustainability, by displaying estimated CO2 emissions generated by each Galaxy job.

Analysis and mapping of global research publications on point-of-care testing for infectious diseases.

This study presents the first comprehensive analysis and mapping of scientific research on point-of-care testing (POCT) in infectious diseases, filling a gap in understanding the evolving landscape of this field. The identification of research themes and global contributions offers valuable insights. This manuscript aims to analyse and map scientific research on POCT in the context of infectious diseases. The study employed a comprehensive search strategy using terms related to POCT and infectious diseases. The search was conducted on the Scopus database, refining results based on inclusion and exclusion criteria. The dataset of 1719 research articles was then subjected to descriptive analysis and mapping using VOSviewer. The research findings indicate an exponential growth in POCT-related publications, with 46.8% published post the COVID-19 pandemic. Plos One journal led in publication frequency, and Biosensors and Bioelectronics received the highest citations per article. North America and Western Europe dominated contributions, with notable participation from China, South Africa, and India. The research landscape revealed the following research themes: detection technologies, human immunodeficiency virus (HIV)/sexually transmitted infection (STI) diagnosis, antibiotic optimisation, and schistosomiasis. Clinical trials focused on antibiotic prescribing, HIV, STIs, and specific infections. The findings suggest a shifting landscape towards POCT, emphasising the need for future planning and investment in healthcare systems. The research identifies areas for future exploration, such as the impact of POCT on antibiotic prescribing and its role in combating infectious diseases in low- and middle-income countries. Implementation of POCT has the potential to revolutionise infectious disease management, improve patient outcomes, and reduce the global burden of diseases. Better public awareness, healthcare team management, and planning for POCT at entry points are crucial for societal benefit. Results demonstrated the evolving role of POCT in infectious disease management and prevention.

Impact of Climate Change on the Environment: A Synthesis Study

Climate change has a significant impact on both physical and social components of the environment. Every component of the environment has been suffering the impacts of climate change. All components of the environment are interrelated through the exchanging of energy and matter; hence they actively interact. Major components of the environment like the biosphere, lithosphere, atmosphere, and hydrosphere are open systems to impact climate change. This paper describes the major impacts of climate change on major components of the environment. This study investigated the current state, wide-range global research trends, and different concerns on the impacts of climate change on the sustainable tourism. Global climate change represents a grand challenge for society, one that is increasingly influencing tourism sector investment, planning, operations, and demand. This study synthesized a total of 36 studies on climate change by sourcing published material from the review that was performed in indexed databases namely Dimensions, Web Science, Elsevier Scopus, and Google Scholar. Therefore, the study found that human beings are the major contributors to climate change through anthropogenic greenhouse gas emissions that worsened during the Green Revolution. Climate change outcomes through the loss of valuable ecosystem goods and services, degrading the most of keystone species sites. In other ways, loss of biodiversity, changes in atmospheric composition, changes in chemical reactions in soil, changes in water quality, availability, and hydrologic cycles, and frequent occurrence of extreme weather conditions. Of course! The effects of climate change are wide-ranging and diverse, impacting many areas and facets of daily life. Therefore, this study recommends implementing carbon pricing mechanisms to internalize the costs of greenhouse gas emissions and enforcing stringent environmental regulations and standards to limit emissions and pollution. Support global efforts and agreements to combat climate change, such as the Paris Agreement.

Bibliometric analysis of hotspots and trends of global myopia research.

To gain insights into the global research hotspots and trends of myopia. Articles were downloaded from January 1, 2013 to December 31, 2022 from the Science Core Database website and were mainly statistically analyzed by bibliometrics software. A total of 444 institutions in 87 countries published 4124 articles. Between 2013 and 2022, China had the highest number of publications (n=1865) and the highest H-index (61). Sun Yat-sen University had the highest number of publications (n=229) and the highest H-index (33). Ophthalmology is the main category in related journals. Citations from 2020 to 2022 highlight keywords of options and reference, child health (pediatrics), myopic traction mechanism, public health, and machine learning, which represent research frontiers. Myopia has become a hot research field. China and Chinese institutions have the strongest academic influence in the field from 2013 to 2022. The main driver of myopic research is still medical or ophthalmologists. This study highlights the importance of public health in addressing the global rise in myopia, especially its impact on children's health. At present, a unified theoretical system is still needed. Accurate surgical and therapeutic solutions must be proposed for people with different characteristics to manage and intervene refractive errors. In addition, the benefits of artificial intelligence (AI) models are also reflected in disease monitoring and prediction.

The global relevance of locally grounded ethnobiology.

While ethnobiology is a discipline that focuses on the local, it has an outstanding, but not yet fully realized potential to address global issues. Part of this unrealized potential is that universalistic approaches often do not fully recognize culturally grounded perspectives and there are multiple challenges with scaling up place-based research. However, scalability is paramount to ensure that the intimate and context-specific diversity of human-environmental relationships and understandings are recognized in global-scale planning and policy development. Here, we identify four pathways to enable the scalability of place-based ethnobiological research from the ground up: local-to-global dialogues, aggregation of published data, multi-sited studies, and geospatial analyses. We also discuss some major challenges and consideration to encourage continuous reflexivity in these endeavours and to ensure that scalability does not contribute to unnecessarily decontextualizing, co-opting, or overwriting the epistemologies of Indigenous Peoples and local communities. As ethnobiology navigates multiple scales of time and space and seeks to increase its breadth, this study shows that the use of deliberately global approaches, when carefully nested within rich field-based and ecological and ethnographically grounded data, can contribute to: (1) upscaling case-specific insights to unveil global patterns and dynamics in the biocultural contexts of Indigenous Peoples and local communities; (2) bringing ethnobiological knowledge into resolutions that can influence global environmental research and policy agendas; and (3) enriching ethnobiology's field-based ethos with a deliberate global analytical focus.

Global health research abstracts: November ‘23

The African Journal of Emergency Medicine, in partnership with several other regional emergency medicine journals, publishes abstracts from each respective journal. Abstracts are not necessarily linked to open access papers however, all abstracts are accessible without subscription.

Evolution and global research trends of immunity in diabetic nephropathy: a bibliometric and visual analysis from 2004 to 2023.

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, with an increasing prevalence worldwide, but its pathomechanisms remain incompletely understood. Accumulatingevidence suggests that immunity plays an important role in the development of DN. Many papers have been published in the field over the last 20years, but there has been no bibliometric review of the research hotspots and trends in the field. This study aimed to assess the current research status and future trends of the link between immune and DN using bibliometric analysis. Publications on the association between immunity and DN from 2004 to 2023 were retrieved from the Web of Science Core Collection database and screened according to inclusion criteria. VOSviewer and CiteSpace software were employed to visualize research trends and hotspots in the field. Data including author, institution, country, journal, reference, and keyword were analyzed. Ultimately 1246 publications meeting the criteria were included in the bibliometric analysis, involving 838 articles (84.96%) and 408 reviews (15.04%). The literature covered 81 countries and regions, 1751 institutions, and 6584 authors. The top 2 countries in terms of the number of publications were China (435) and the United States (318), and they collaborated most frequently. The United States had the highest number of citations for published papers (18,161), far exceeding the other countries. England had 38 publications but had the highest average number of citations (92.32). The University of California system was the most prolific institution (25 papers, 1062 citations, 42.48 citations per paper). Frontiers in Immunology was the most prolific journal in the field (30 papers). The most cited journal was Kidney International (863 citations). The analysis of keywords and references showed that inflammation, ferroptosis, and lipid metabolism may be future research hotspots in this field. The number of publications related to immunity and DN has increased annually over the past 20years, with a significant increase in the last 3years especially. Our results identified research hotspots and trends in the field. These findings provide valuable perspectives for future research, enhancing our understanding of the immune-related mechanisms of DN and exploring potential therapeutic strategies.

Global research landscape and trends of cancer stem cells from 1997 to 2023: A bibliometric analysis.

Cancer stem cells (CSCs) are a subset of cells with self-renewal ability and tumor generating potential. Accumulated evidence has revealed that CSCs were shown to contribute to tumorigenesis, metastasis, recurrence and resistance to chemoradiotherapy. Therefore, CSCs were regarded as promising therapeutic targets in cancer. This study is the first to reveal the development process, research hotspots, and trends of entire CSCs research field through bibliometric methods. All relevant publications on CSCs with more than 100 citations (notable papers) and the 100 most cited papers (top papers) during 1997 to 2023 were extracted and analyzed. Cancer research published the largest number of papers (184 papers). The USA accounted for the most publications (1326 papers). Rich, JN was the author with the most publications (56 papers) and the highest M-index (3.111). The most contributive institution was the University of Texas System (164 papers). Before 2007, research mainly focused on the definition and recognition of CSCs. Between 2007 and 2016, with the emergence of the terms such as "sonic hedgehog," "metabolism," "oxidative phosphorylation," and "epithelial mesenchymal transition," research began to shift toward exploring the mechanisms of CSCs. In 2016, the focus transitioned to the tumor microenvironment and the ecological niches. The analysis of papers published in major journals since 2021 showed that "transcription," "inhibition," and "chemoresistance" emerged as new focused issues. In general, the research focus has gradually shifted from basic biology to clinical transformation. "Tumor microenvironment" and "chemo-resistance" should be given more attention in the future.

Embracing the hidden potential: The contribution of majority world research to developmental science.

Research on adolescence from the Majority World possesses major hidden potential in contributing to global adolescent research and developmental science more broadly. In this commentary, the authors (1) describe the background and the process through which this special issue came into fruition, (2) introduce the emic approaches to study the influences of macro-contextual variations on developmental science and provide several pertinent examples on the contributions of Majority World research, (3) elaborate on challenges and barriers that Majority World scholars often face in conducting and disseminating their research, and (4) a few actionable steps and recommendations in promoting the representation and inclusion of Majority World research into global developmental science. Only when our field fully integrates findings from all regions of the world will we be able to develop a fundamental scientific representation and understanding of what it means to be an adolescent, how adolescents develop over time, and what tasks or phenomena in adolescent development are truly universal or specific to particular groups, regions, or areas.

Promoting sustainable smallholder farming via multistakeholder collaboration

Transforming smallholder farms is critical to global food security and environmental sustainability. The science and technology backyard (STB) platform has proved to be a viable approach in China. However, STB has traditionally focused on empowering smallholder farmers by transferring knowledge, and wide-scale adoption of more sustainable practices and technologies remains a challenge. Here, we report on a long-term project focused on technology scale-up for smallholder farmers by expanding and upgrading the original STB platform (STB 2.0). We created a formalized and standardized process by which to engage and collaborate with farmers, including integrating their feedback via equal dialogues in the process of designing and promoting technologies. Based on 288 site-year of field trials in three regions in the North China Plain over 5 y, we find that technologies cocreated through this process were more easily accepted by farmers and increased their crop yields and nitrogen factor productivity by 7.2% and 28.1% in wheat production and by 11.4% and 27.0% in maize production, respectively. In promoting these technologies more broadly, we created a "one-stop" multistakeholder program involving local government agencies, enterprises, universities, and farmers. The program was shown to be much more effective than the traditional extension methods applied at the STB, yielding substantial environmental and economic benefits. Our study contributes an important case study for technology scale-up for smallholder agriculture. The STB 2.0 platform being explored emphasizes equal dialogue with farmers, multistakeholder collaboration, and long-term investment. These lessons may provide value for the global smallholder research and practitioners.

Degendering Menstruation: A Scoping Review Exploring the Experiences of Transgender and Non-Binary People

ABSTRACT Menstruation is a biological process experienced by up to 800 million people on any given day. Historically, menstruation has been studied from the female perspective. However, it should be considered that not all who menstruate are women. Therefore, the purpose of this research was to determine the status of evidence on transgender and non-binary individuals’ experiences with menstruation. Arksey and O’Malley’s (2005) framework for conducting a scoping study was used to guide this review. The authors used five steps of the six-step process to identify the research problem and search strategy, select studies based on defined inclusion and exclusion criteria, extract key information from five selected studies, and chart, summarize, and report the results as themes. The analysis resulted in the identification of four themes: (1) gender dysphoria and the influence on identity; (2) menstrual management and transformation as a turning point; (3) managing menstruation in precarious spaces; and (4) moving toward an open dialogue. Findings suggest a need for awareness of diverse and inclusive menstrual experiences. Inclusive advertising and menstrual products are needed to support transgender and non-binary people and reduce gender dysphoria. Policy initiatives should support the reconceptualization of infrastructure so that bathrooms are safe and comfortable places. Future opportunities for research exploring menstrual management within transgender and non-binary populations with emphasis on global research with diverse cultures and social structures is necessary to address gaps in the existing literature.

Global status and trends of metabolomics in diabetes: A literature visualization knowledge graph study.

Diabetes is a metabolic disease characterized by hyperglycemia, which has increased the global medical burden and is also the main cause of death in most countries. To understand the knowledge structure of global development status, research focus, and future trend of the relationship between diabetes and metabolomics in the past 20 years. The articles about the relationship between diabetes and metabolomics in the Web of Science Core Collection were retrieved from 2002 to October 23, 2023, and the relevant information was analyzed using CiteSpace6.2.2R (CiteSpace), VOSviewer6.1.18 (VOSviewer), and Bibliometrix software under R language. A total of 3123 publications were included from 2002 to 2022. In the past two decades, the number of publications and citations in this field has continued to increase. The United States, China, Germany, the United Kingdom, and other relevant funds, institutions, and authors have significantly contributed to this field. Scientific Reports and PLoS One are the journals with the most publications and the most citations. Through keyword co-occurrence and cluster analysis, the closely related keywords are "insulin resistance", "risk", "obesity", "oxidative stress", "metabolomics", "metabolites" and "biomarkers". Keyword clustering included cardiovascular disease, gut microbiota, metabonomics, diabetic nephropathy, molecular docking, gestational diabetes mellitus, oxidative stress, and insulin resistance. Burst detection analysis of keyword depicted that "Gene", "microbiota", "validation", "kidney disease", "antioxidant activity", "untargeted metabolomics", "management", and "accumulation" are knowledge frontiers in recent years. The relationship between metabolomics and diabetes is receiving extensive attention. Diabetic nephropathy, diabetic cardiovascular disease, and kidney disease are key diseases for future research in this field. Gut microbiota, molecular docking, and untargeted metabolomics are key research directions in the future. Antioxidant activity, gene, validation, mass spectrometry, management, and accumulation are at the forefront of knowledge frontiers in this field.

Global research trend and hotspot in the low FODMAP diet: a bibliometric analysis

HighlightsThe low FODMAP diet is the most recommended dietary intervention for the clinical management of IBS symptoms.Bibliometrics analysis provides a comprehensive perspective and direction on global research trend and hotspot in the low FODMAP diet research.The restriction stage of the low FODMAP diet is superior to other dietary therapies for IBS in terms of symptom response, but it has a negative impact on the abundance of gut Bifidobacteria and diet quality.Identification of biomarkers to predict response to the low FODMAP diet has become the current research hotspot.Large, well-designed clinical research studies are needed in the future to investigate the long-term efficacy and safety of the low FODMAP diet, including FODMAP reintroduction and personalization stages.

One index, two publishers and the global research economy

ABSTRACT The emergence of a global science system after the second world war was spurred by transformations in academic publishing and information science. Amidst Russian-American technological rivalries, funding for science expanded rapidly. Elsevier and Pergamon internationalised journal publishing, whilst tools such as the Science Citation Index changed the way research was measured and valued. This paper traces the connections between the post-war expansion of academic research, new commercial publishing models, the management of research information and Cold War geopolitics. Today, the analysis and use of research metadata continues to revolutionise science communication. The monetisation of citation data has led to the creation of rival publishing platforms and citation infrastructures. The value of this data is amplified by digitisation, computing power and financial investment. Corporate ownership and commercial competition reinforce geographical and resource inequalities in a global research economy, marginalising non-Anglophone knowledge ecosystems as well as long-established scholar-led serials and institutional journals. The immediate future for academic publishing will be shaped by a growing divide between commercial and ‘community-owned’ open science infrastructures.

Systematic Review of Global Research on Acculturation of International Students (2003-2023)

Aim: This paper presents a scientometric review of global articles regarding acculturation of international students (AoIS), published from 2003 to 2023 and indexed in the Web of Science Core Collection (WoSCC), to provide a quantifiable snapshot of the field. Methodology: Bibliographic information was extracted from WoSCC. Refined data were visualized using CiteSpace. Conclusion: Worldwide publications have been increasing continuously since 2013, with a staged development among relevant disciplines. Limited collaborations have been found among countries, institutions, and posting authors, however a gradual trend toward transnational teamwork has been emerging. Research foci mainly concentrate on macro factors of acculturation. Research gaps have also been revealed, as hotspots in recent pedagogical research field have not been adopted in studies of AoIS.

Trigger mechanism centralized but discursive frame fragmented: China as a case for studying populism at the grassroots level in the social media age

ABSTRACT While most research focuses on top-down populism practiced by political actors in democratic countries, we paid attention to populist phenomena at the grassroots level in an authoritarian context. Specifically, we proposed a perspective of investigating populist discourse embedded in public opinion and adopted a fine-grained discursive frame approach to study Chinese online populism. Using large-scale social media data around trending events and employing cutting-edge computational semantic analysis methods, we discovered that economic anxiety is central to the trigger mechanism of Chinese online populism, and the specific populist discourse is fragmented in terms of ideological resources, cultural toolboxes, and semantic structure. This study not only provides a more comprehensive understanding of contemporary Chinese populism phenomena, but it also contributes to global populism research by providing valuable empirical evidence in authoritarian contexts and broadening the theoretical perspective of studying populism at the grassroots level.

Global research trends in nursing leadership from 1985 to 2022: a bibliometric analysis.

Developing nursing leadership has become a key policy priority to achieve universal health coverage. This study aims to explore the current status, developing trends and research frontiers in the field of nursing leadership. In total, 1,137 articles and reviews on nursing leadership from 1985 to 2022 were retrieved from the Web of Science Core Collection database. Trends of publications, journals, countries/regions, institutions, documents and keywords were visualized and analyzed using Microsoft Excel and CiteSpace software. Nursing leadership research showed an overall increase in number despite slight fluctuations in annual publications. The USA was the leading country in nursing leadership research, and the University of Alberta was the most productive institution. The Journal of Nursing Management was the most widely published journal that focused on nursing leadership, followed by the Journal of Nursing Administration. Keyword analysis showed that the main research hotspots of nursing leadership are improvement, practice and impact of nursing leadership. This article summarizes the current state and frontiers of nursing leadership for researchers, managers and policy makers, as well as follow-up, development and implementation of nursing leadership. More research is needed that focuses on the improvement, practice and impact of nursing leadership, which are cyclical, complementary and mutually reinforcing. Longitudinal and intervention studies of nursing leadership, especially on patient prognosis, are also particularly needed.

Green and chemical syntheses of silver nanoparticles: Comparative and comprehensive study on characterization, therapeutic potential, and cytotoxicity

The emergence of metallic nanoparticles through green synthesis has garnered significant recognition, shaping global research efforts towards eco-friendly practices, often termed as the green revolution. Specifically, the green synthesis of silver nanoparticles (AgNPs) has made considerable strides in the past decade, becoming a prominent fixture in the realm of science and technology. The study explores the synthesis and characterization of silver nanoparticles (AgNPs) using Cassia fistula L. flowers extract through chemical co-precipitation (CM_AgNPs) and green methods (CFF_AgNPs). Characterization techniques, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), attenuated total reflectance fourier-transform infrared (FTIR), and X-ray diffraction (XRD), revealed irregular morphologies with agglomeration, polycrystalline nature, and intrinsic functional groups involved in capping AgNPs. Antioxidant assessment demonstrated superior antioxidative activity (84.48 %) in green-synthesized nanoparticles compared to chemically synthesized ones (75.87 %), and they exhibited dose-dependent anti-inflammatory effects with IC50 values CFF_AgNPs_30.19 μg/mL and CM_AgNPs _34.14 μg/mL respectively. The lower IC50 value of CFF_AgNPs_30.19 μg/mL signifies finer and better activity due to the presence of phytochemicals present in it. Whereas for CM_AgNPs the IC50 value is a 34.14 μg/mL which is solely due to AgNPs. To ensure the promising therapeutic aspects of AgNPs with a careful assessment of their safety profile, cytotoxicity of AgNPs on HEP3B cancer cells was evaluated through MTT assay, lactate dehydrogenase (LDH) release, and reactive oxygen species (ROS) level measurement. In the in vitro cytotoxicity evaluation, HEP3B demonstrated more pronounced dose-dependent adverse effects upon exposure to CFF_AgNPs compared to CM_AgNPs. This study underscores the bioactive potential of Cassia fistula L. mediated AgNPs, suggesting promising applications in biomedicine with environmental sustainability. The findings contribute to the growing interest in green synthesis methods for metallic nanoparticles and their potential benefits in various fields.