Amid escalating global energy demands and environmental concerns, the transition to renewable sources like solar power is imperative. Despite the advancements in photovoltaic (PV) technology promising increased efficiency, soiling on PV panels—composed of dust, bird droppings, and contaminants—poses a significant challenge, obstructing sunlight and reducing energy conversion efficiency. Building upon existing research on titanium dioxide (TiO2) nanoparticle coatings, our study investigates their super-hydrophilic and anti-soiling characteristics to enhance self-cleaning capabilities in solar applications. Furthermore, our research investigates the application of (3-aminopropyl)trimethoxy silane as an interlayer to reinforce the adherence of the TiO2 coating to PV panel glass, thereby enhancing its durability. Preliminary results highlight the coating’s exceptional super-hydrophilic properties, with water contact angle measurements less than 10°, indicative of TiO2’s strong water affinity. Spectrophotometer measurements show that the developed coating maintains high optical transmittances for the wavelength range from 350 to 800 nm, which is the most crucial factor for energy conversion in solar panels. Our contributions aim to advance solar energy technologies and support the shift towards more sustainable energy solutions, highlighting the role of innovative materials science in addressing solar power’s operational challenges.