Giant Condyloma Acuminata (Buschke and Lowenstein tumours) is a variation of condyloma caused by a sexually transmitted virus infection. Although it is a benign disease, it carries a risk of malignant transformation. Primary locations of giant condyloma are the perianal region and the external genitalia. We report an asymptomatic case of inguinal and perineal giant acuminata condyloma in a 46-year-old male of eight years evolution. After the surgical resection ultrasonic scalpel, the patient is free of recurrence twelve months later.