Ghost imaging (GI) is capable of reconstructing images under low-light conditions by single-pixel measurements. However, improving image resolution often requires extensive single-pixel sampling, limiting practical applications. Here we propose a super-resolution algorithm of GI using Convolutional neural network with Grouped orthonormalization algorithm Constraint (GICGC), which aims to reconstruct images at super-resolution with strong local regularities and self-similarity. The proposed algorithm, a versatile approach, has been demonstrated to outperform several other widely used GI algorithms in terms of spatial resolution and sampling rate. Our findings are supported by rigorous benchmark tests and experimental validations in challenging environments, including multimode fibers. The imaging experimental results demonstrate that GICGC achieves superior performance in reconstructing image linewidth and contrast, effectively doubling resolution capability by approximately 2.1 times, indicating significant potential in biomedical imaging and other fields. We believe this study represents a novel breakthrough in universal super-resolution ghost imaging and paves the way for its practical applications.
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