Landslides are a rare but hazardous geological phenomenon in Egypt, with the El Mokattam plateau situated in the eastern part of Cairo covering approximately 64 km2 and ranging in elevation from 50–205 m. This study aims to identify and monitor landslides in the area using various geophysical methods. Twelve Electrical resistivity tomography (ERT) profiles ,twenty-two P-wave Seismic Refraction profiles, twenty-two Refraction microtremors profiles, three ground penetrating radar (GPR) profiles and borehole data were utilized to analyze the occurrence of landslides in the El Mokattam Plateau. Additionally, we employed a relatively new geophysical method, studying high-frequency microtremor sounds emitted from landslide collapses at 22 stations. Our analysis identified steep slopes, jointed or fractured rocks, and irrigation water as primary factors contributing to landslides, with irrigation water acting as a lubricant for clays and promoting ground sliding. Examination of high-frequency microtremor sounds revealed a potential correlation between vertical high-frequency spectra at 100 Hz and landslide collapses, which aids in the identification of landslide-prone zones. Therefore, we conclude that seismological studies, particularly spectral analysis of high-frequency and low-amplitude sounds (microtremors) emitted from soil, offer a promising approach for investigating landslides.